Ordered self-assembly mechanism of a spherical oncoprotein oligomer triggered by zinc removal and stabilized by an intrinsically disordered domain

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  Smal, Clara ^a   Alonso, Leonardo G ^b   Wetzler, Diana E ^c   Heer, Angeles ^a   de Prat Gay, Gonzalo ^a  

^a FUNDACIÓN INSTITUTO LELOIR   (Argentina)

^b XBio Inc   (Argentina)

^c UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; AMYLOID PROTEIN; CHAPERONE; OLIGOMER; PROTEIN E7; ZINC; ONCOGENE PROTEIN E7, HUMAN PAPILLOMAVIRUS TYPE 16;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CIRCULAR DICHROISM; CONCENTRATION (PARAMETERS); DRUG RESEARCH; IMMUNOGENICITY; KINETICS; NANOTECHNOLOGY; OLIGOMERIZATION; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN POLYMERIZATION; PROTEIN QUATERNARY STRUCTURE; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; PROTEIN TERTIARY STRUCTURE; WART VIRUS; CHEMISTRY; GENETICS; HUMAN; HUMAN PAPILLOMAVIRUS TYPE 16; METABOLISM; PROTEIN MULTIMERIZATION;

HUMAN PAPILLOMAVIRUS;

HUMAN PAPILLOMAVIRUS 16; HUMANS; PAPILLOMAVIRUS E7 PROTEINS; PROTEIN MULTIMERIZATION; PROTEIN STABILITY; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; ZINC;

EID: 84860755706     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0036457     Document Type: Article

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