Sirolimus-associated testicular toxicity: Detrimental but reversible

Transplantation

Volumn 93, Issue 9, 2012, Pages 874-879

  Rovira, Jordi ^a   Diekmann, Fritz ^a   Ramírez Bajo, María José ^a   Bañón Maneus, Elisenda ^a   Moya Rull, Daniel ^a   Campistol, Josep M ^a  

^a HOSPITAL CLÍNIC   (Spain)

Author keywords

Gonadal function; Rapamycin; Spermatogenesis; Testosterone

Indexed keywords

FOLLITROPIN; LUTEINIZING HORMONE; RAPAMYCIN; STEROIDOGENIC ACUTE REGULATORY PROTEIN; TESTOSTERONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BODY WEIGHT; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFICACY; FOLLITROPIN BLOOD LEVEL; GONAD FUNCTION; LUTEINIZING HORMONE BLOOD LEVEL; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SEMINIFEROUS TUBULE; SPERMATID; SPERMATOCYTE; SPERMATOGENESIS; SPERMATOGONIUM; SPERMATOZOON COUNT; TESTIS DISEASE; TESTIS WEIGHT; TESTOSTERONE BLOOD LEVEL; TESTOSTERONE SYNTHESIS; TREATMENT DURATION;

ANIMALS; APOPTOSIS; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; FOLLOW-UP STUDIES; IMMUNOSUPPRESSIVE AGENTS; INJECTIONS, INTRAPERITONEAL; MALE; ORGAN SIZE; PHOSPHOPROTEINS; RATS; RATS, WISTAR; SIROLIMUS; SPERMATOGENESIS; TESTICULAR DISEASES; TESTIS; TESTOSTERONE; TOR SERINE-THREONINE KINASES;

EID: 84860743864     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0b013e31824bf1f0     Document Type: Article

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