Detoxification of H2S by differentiated colonic epithelial cells: Implication of the sulfide oxidizing unit and of the cell respiratory capacity

Antioxidants and Redox Signaling

Volumn 17, Issue 1, 2012, Pages 1-10

  Mimoun, Sabria ^a   Andriamihaja, Mireille ^a   Chaumontet, Catherine ^a   Atanasiu, Calina ^b   Benamouzig, Robert ^a,b   Blouin, Jean Marc ^a   Tomé, Daniel ^a   Bouillaud, Frédéric ^c   Blachier, François ^a  

^a INRA Institut National de la Recherche Agronomique   (France)

^b AVICENNE HOSPITAL   (France)

^c INSTITUT COCHIN   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BUTYRIC ACID; CALCIUM; DIOXYGENASE; HYDROGEN SULFIDE; IRON; OXIDOREDUCTASE; SULFIDE; SULFIDE QUINONE REDUCTASE; SULFURTRANSFERASE; THIOSULFATE SULFUR TRANSFERASE; UNCLASSIFIED DRUG; ZINC;

ADULT; AGED; BRAIN DISEASE; CELL DIFFERENTIATION; CELL RESPIRATION; CLINICAL ARTICLE; COLON BIOPSY; COLON MUCOSA; CONTROLLED STUDY; DETOXIFICATION; EPITHELIUM CELL; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; LARGE INTESTINE; MALE; MICROFLORA; MITOCHONDRIAL RESPIRATION; OXIDATION; OXYGEN CONSUMPTION; PRIORITY JOURNAL; REVIEW;

CELL RESPIRATION; COLON; EPITHELIAL CELLS; HT29 CELLS; HUMANS; HYDROGEN SULFIDE; QUINONE REDUCTASES; SULFIDES; THIOSULFATE SULFURTRANSFERASE;

EID: 84860735776     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2011.4186     Document Type: Review

References (37)

1. Andriamihaja M, Chaumontet C, Tome D, and Blachier F. Butyrate metabolism in human colon carcinoma cells: implications concerning its growth-inhibitory effect. J Cell Physiol 218: 58-65, 2009.
2. Andriamihaja M, Davila AM, Eklou-Lawson M, Petit N, Delpal S, Allek F, Blais A, Delteil C, Tome D, and Blachier F. Colon luminal content and epithelial cell morphology are markedly modified in rats fed with a high-protein diet. Am J Physiol 299: G1030-G1037, 2010.
3. Attene-Ramos MS, Nava GM, Muellner MG, Wagner ED, PlewaMJ, and Gaskins HR. DNA damage and toxicogenomic analyses of hydrogen sulfide in human intestinal epithelial FHs 74 Int cells. Environ Mol Mutagen 51: 304-314, 2010.
4. Attene-Ramos MS, Wagner ED, Gaskins HR, and Plewa MJ. Hydrogen sulfide induces direct radical-associated DNA damage. Mol Cancer Res 5: 455-459, 2007.
5. Attene-Ramos MS, Wagner ED, Plewa MJ, and Gaskins HR. Evidence that hydrogen sulfide is a genotoxic agent. Mol Cancer Res 4: 9-14, 2006.
6. Blachier F, Davila AM, Mimoun S, Benetti PH, Atanasiu C, Andriamihaja M, Benamouzig R, Bouillaud F, and Tome D. Luminal sulfide and large intestine mucosa: friend or foe? Amino acids 39: 335-347, 2010.
7. Bouillaud F and Blachier F. Mitochondria and sulfide: a very old story of poisoning, feeding, and signaling? Antioxid Redox Signal 15: 379-391, 2011.
8. Caliendo G, Cirino G, Santagada V, and Wallace JL. Synthesis and biological effects of hydrogen sulfide (H2S): development of H2S-releasing drugs as pharmaceuticals. J Med Chem 53: 6275-6286, 2010.
9. Flannigan KL, McCoy KD, and Wallace JL. Eukaryotic and Prokaryotic Contributions to Colonic Hydrogen Sulfide Synthesis. Am J Physiol Gastrointest Liver Physiol 301: G188-G193, 2011.
10. Florin T, Neale G, Gibson GR, Christl SU, and Cummings JH. Metabolism of dietary sulphate: absorption and excretion in humans. Gut 32: 766-773, 1991.
11. Furne J, Springfield J, Koenig T, DeMaster E, and Levitt MD. Oxidation of hydrogen sulfide and methanethiol to thiosulfate by rat tissues: a specialized function of the colonic mucosa. Biochem Pharmacol 62: 255-259, 2001.
12. Gibson GR, Cummings JH, and Macfarlane GT. Use of a three-stage continuous culture system to study the effect of mucin on dissimilatory sulfate reduction and methanogenesis by mixed populations of human gut bacteria. Appl Environ Microbiol 54: 2750-2755, 1988.
13. Goubern M, Andriamihaja M, Nubel T, Blachier F, and Bouillaud F. Sulfide, the first inorganic substrate for human cells. Faseb J 21: 1699-1706, 2007.
14. Hambidge KM, Miller LV, Westcott JE, Sheng X, and Krebs NF. Zinc bioavailability and homeostasis. Am J Clin Nutr 91: 1478S-1483S, 2010.
15. Hara H, Konishi A, and Kasai T. Contribution of the cecum and colon to zinc absorption in rats. J Nutr 130: 83-89, 2000.
16. Hildebrandt TM and Grieshaber MK. Three enzymatic activities catalyze the oxidation of sulfide to thiosulfate in mammalian and invertebrate mitochondria. FEBS J 275: 3352-3361, 2008.
17. Hill BC, Woon TC, Nicholls P, Peterson J, Greenwood C, and Thomson AJ. Interactions of sulphide and other ligands with cytochrome c oxidase. An electron-paramagnetic-resonance study. Biochem J 224: 591-600, 1984.
18. Jorgensen J and Mortensen PB. Hydrogen sulfide and colonic epithelial metabolism: implications for ulcerative colitis. Dig Dis Sci 46: 1722-1732, 2001.
19. Jorgensen J and Mortensen PB. Substrate utilization by intestinal mucosal tissue strips from patients with inflammatory bowel disease. Am J Physiol 281: G405-G411, 2001.
20. Kristensen MB, Hels O, Morberg CM, Marving J, Bugel S, and Tetens I. Total zinc absorption in young women, but not fractional zinc absorption, differs between vegetarian and meat-based diets with equal phytic acid content. Br J Nutr 95: 963-967, 2006.
21. Lagoutte E, Mimoun S, Andriamihaja M, Chaumontet C, Blachier F, and Bouillaud F. Oxidation of hydrogen sulfide remains a priority in mammalian cells and causes reverse electron transfer in colonocytes. Biochim Biophys Acta 1797: 1500-1511, 2010.
22. Leschelle X, Delpal S, Goubern M, Blottiere HM, and Blachier F. Butyrate metabolism upstream and downstream acetyl-CoA synthesis and growth control of human colon carcinoma cells. Eur J Biochem/FEBS 267: 6435-6442, 2000.
23. Leschelle X, Goubern M, Andriamihaja M, Blottiere HM, Couplan E, Gonzalez-Barroso MD, Petit C, Pagniez A, Chaumontet C, Mignotte B, Bouillaud F, and Blachier F. Adaptative metabolic response of human colonic epithelial cells to the adverse effects of the luminal compound sulfide. Biochim Biophys Acta 1725: 201-212, 2005.
24. Levitt MD, Furne J, Springfield J, Suarez F, and DeMaster E. Detoxification of hydrogen sulfide and methanethiol in the cecal mucosa. J Clin Invest 104: 1107-1114, 1999.
25. Lin H. Stem cells: to be and not to be. Nature 425: 353-355, 2003.
26. Lowry OH, Rosebrough NJ, Farr AL, and Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265-275, 1951.
27. Macfarlane GT, Gibson GR, and Cummings JH. Comparison of fermentation reactions in different regions of the human colon. J Appl Bacteriol 72: 57-64, 1992.
28. Moore KA and Lemischka IR. Stem cells and their niches. Science 311: 1880-1885, 2006.
29. Nagatsu T, Hino M, Fuyamada H, Hayakawa T, and Sakakibara S. New chromogenic substrates for X-prolyl dipeptidyl-aminopeptidase. Anal Biochem 74: 466-476, 1976.
30. Nicholls P. Inhibition of cytochrome c oxidase by sulphide. Biochem Soc Trans 3: 316-319, 1975.
31. Ramasamy S, Singh S, Taniere P, Langman MJ, and Eggo MC. Sulfide-detoxifying enzymes in the human colon are decreased in cancer and upregulated in differentiation. Am J Physiol 291: G288-G296, 2006.
32. Reiffenstein RJ, Hulbert WC, and Roth SH. Toxicology of hydrogen sulfide. Annu Rev Pharmacol Toxicol 32: 109-134, 1992.
33. Suarez F, Furne J, Springfield J, and Levitt M. Production and elimination of sulfur-containing gases in the rat colon. Am J Physiol 274: G727-G733, 1998.
34. Szabo C. Hydrogen sulphide and its therapeutic potential. Nat Rev 6: 917-935, 2007.
35. Tiranti V, Viscomi C, Hildebrandt T, Di Meo I, Mineri R, Tiveron C, Levitt MD, Prelle A, Fagiolari G, Rimoldi M, and Zeviani M. Loss of ETHE1, a mitochondrial dioxygenase, causes fatal sulfide toxicity in ethylmalonic encephalopathy. Nat Med 15: 200-205, 2009.
36. Yoshikawa S. X-ray structure and reaction mechanism of bovine heart cytochrome c oxidase. Biochem Soc Trans 27: 351-362, 1999.
37. Zweibaum A, Pinto M, Chevalier G, Dussaulx E, Triadou N, Lacroix B, Haffen K, Brun JL, and Rousset M. Enterocytic differentiation of a subpopulation of the human colon tumor cell line HT-29 selected for growth in sugarfree medium and its inhibition by glucose. J Cell Physiol 122: 21-29, 1985.