Effects of emodin on gene expression profile in small cell lung cancer NCI-H446 cells

Chinese Medical Journal

Volumn 120, Issue 19, 2007, Pages 1710-1715

  Fu, Zhong Yan ^a,b   Han, Jin Xiang ^a,b   Huang, Hai Yan ^a  

^a BEIJING HOSPITAL   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

Emodin; Gene expression profile; Small cell lung cancer

Indexed keywords

CASPASE 3; COMPLEMENTARY DNA; EMODIN;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL ADHESION; CELL CYCLE REGULATION; CELL FUNCTION; CELL VIABILITY; CONTROLLED STUDY; CYTOSKELETON; DNA MICROARRAY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME ASSAY; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LUNG SMALL CELL CANCER; METABOLIC PARAMETERS; METASTASIS; NITROBLUE TETRAZOLIUM TEST; NUCLEOTIDE SEQUENCE; PROTEIN SYNTHESIS; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA PROCESSING; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION; VALIDATION PROCESS;

EID: 35348962760     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00029330-200710010-00014     Document Type: Article

References (26)

1. Rosti G, Carminati O, Monti M, Tamberi S, Marangolo M. Chemotherapy advances in small cell lung cancer. Ann Oncol 2006; Suppl 5: v99-v102.
2. Wang HH, Chung JG. Emodin-induced inhibition of growth and DNA damage in the Helicobacter pylori. Curr Microbiol 1997; 35: 262-266.
3. Chang CH, Lin CC, Yang JJ, Namba T, Hattori M. Anti-inflammatory effects of emodin from ventilago leiocarpa. Am J Chin Med 1996; 24: 139-142.
4. Huang HC, Chang JH, Tung SF, Wu RT, Foegh ML, Chu SH. Immunosuppressive effect of emodin, a free radical generator. Eur J Pharmacol 1992; 211: 359-364.
5. Jing X, Ueki N, Cheng J, Imanishi H, Hada T. Induction of apoptosis in hepatocellular carcinoma cell lines by emodin. Jpn J Cancer Res 2002; 93: 874-882.
6. Srinivas G, Anto RJ, Srinivas P, Vidhyalakshmi S, Senan VP, Karunagaran D. Emodin induces apoptosis of human cervical cancer cells through poly (ADP-ribose) polymerase cleavage and activation of caspase-9. Eur J Pharmacol 2003; 473: 117-125.
7. Huang Q, Shen HM, Ong CN. Emodin inhibits tumor cell migration through suppression of the phosphatidylinositol 3-kinase-Cdc42/Rac1 pathway. Cell Mol Life Sci 2005; 62: 1167-1175.
8. Gao XQ, Han JX, Huang HY, Yan S, Song CZ, Huang HN. Effects of aspirin on metastasis-associated gene expression detected by cDNA microarray. Acta Pharmacol Sin 2004; 25: 1327-1333.
9. Vasseur S, Hoffmeister A, Garcia-Montero A, Mallo GV, Feil R, Kuhbandner S, et al. p8-deficient fibroblasts grow more rapidly and are more resistant to adriamycin-induced apoptosis. Oncogene 2002; 21: 1685-1694.
10. Waragai M, Lammers CH, Takeuchi S, Imafuku I, Udagawa Y, Kanazawa I. PQBP-1, a novel polyglutamine tract-binding protein, inhibits transcription activation by Brn-2 and affects cell survival. Hum Mol Genet 1999; 8: 977-987.
11. Ziebold U, Lee EY, Bronson RT, Lees JA. E2F3 loss has opposing effects on different pRB-deficient tumors, resulting in suppression of pituitary tumors but metastasis of medullary thyroid carcinomas. Mol Cell Biol 2003; 28: 6542-6552.
12. Orlic M, Spencer CE, Wang L, Gallie BL. Expression analysis of 6p22 genomic gain in retinoblastoma. Genes Chromosomes Cancer 2006; 45: 72-82.
13. Oeggerli M, Tomovska, S, Schraml P, Calvano-Forte D, Schafroth S, Simon R, et al. E2F3 amplification and overexpression is associated with invasive tumor growth and rapid tumor cell proliferation in urinary bladder cancer. Oncogene 2004; 23: 5616-5623.
14. Sasaki H, Moriyama S, Nakashima Y, Kobayashi Y, Kiriyama M, Fukai I, et al. Histone deacetylase 1 mRNA expression in lung cancer. Lung Cancer 2004; 46: 171-178.
15. Dutta R, Sens DA, Somji S, Sens MA, Garrett SH. Metallothionein isoform 3 expression inhibits cell growth and increases drug resistance of PC-3 prostate cancer cells. Prostate 2002; 52: 89-97.
16. Sunaga N, Miyajima K, Suzuki M, Sato M, White MA, Ramirez RD, et al. Different roles for caveolin-1 in the development of non-small cell lung cancer versus small cell lung cancer. Cancer Res 2004; 64: 4277-4285.
17. Scheffer GL, de Jong MC, Monks A, Flens MJ, Hose CD, Izquierdo MA, et al. Increased expression of beta 2-microglobulin in multidrug-resistant tumour cells. Br J Cancer 2002; 86: 1943-1950.
18. Dutta N, Majumder D, Gupta A, Mazumder DN, Banerjee S. Analysis of human lymphocyte antigen class I expression in gastric cancer by reverse transcriptase-polymerase chain reaction. Hum Immunol 2005; 66: 164-169.
19. Hirankarn N, Kimkong I, Mutirangura A. HLA-E polymorphism in patients with nasopharyngeal carcinoma. Tissue Antigens 2004; 64: 588-592.
20. Fais F, Tenca C, Cimino G, Coletti V, Zanardi S, Bagnara D, et al. CD1d expression on B-precursor acute lymphoblastic leukemia subsets with poor prognosis. Leukemia 2005; 19: 551-556.
21. Sakamoto M, Kondo A, Kawasaki Y, Goto T, Sakamoto H, Miyake K, et al. Analysis of gene expression profiles associated with cisplatin resistance in human ovarian cancer cell lines and tissues using cDNA microarray. Hum Cell 2001; 14: 305-315.
22. Kondo M, Ji L, Kamibayashi C, Tomizawa Y, Randle D, Sekido Y, et al. Overexpression of candidate tumor suppressor gene FUS1 isolated from the 3p21.3 homozygous deletion region leads to G1 arrest and growth inhibition of lung cancer cells. Oncogene 2001; 20: 6258-6262.
23. Gysin S, Rickert P, Kastury K, McMahon M. Analysis of genomic DNA alterations and mRNA expression patterns in a panel of human pancreatic cancer cell lines. Genes Chromosomes Cancer 2005; 44: 37-51.
24. Kasahara K, Fujimura M, Bando T, Shibata K, Shirasaki H, Matsuda T. Modulation of sensitivity to cis-diamminedichloroplatinum (II) by thromboxane A2 receptor antagonists in non-small-cell lung cancer cell lines. Br J Cancer 1996; 74: 1553-1558.
25. Zhu X, Jiang J, Shen H, Wang H, Zong H, Li Z, et al. Elevated beta1,4-galactosyltransferase I in highly metastatic human lung cancer cells. Identification of E1AF as important transcription activator. J Biol Chem 2005; 280: 12503-12516.
26. Bister VO, Salmela MT, Kaijalainen-Lindsberg ML, Uria J, Lohi J, Puolakkainen P, et al. Differential expression of three matrix metalloproteinases, MMP-19, MMP-26, and MMP-28, in normal and inflamed intestine and colon cancer. Dig Dis Sci 2004; 49: 653-661.