Influence of survivin and Bcl-2 expression on the biological behavior of non-small cell lung cancer

Molecular Medicine Reports

Volumn 5, Issue 6, 2012, Pages 1409-1414

  Gao, Qin ^a   Yang, Sheng ^a   Kang, Ming Qiang ^a  

^a FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

Bcl 2; Biological behavior; Immunohistochemistry; Non small cell lung cancer; Prognosis; Survivin

Indexed keywords

PROTEIN BCL 2; SURVIVIN;

ADULT; AGED; ARTICLE; CANCER INVASION; CANCER PROGNOSIS; CANCER STAGING; CANCER SURVIVAL; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE MARKER; FEMALE; FOLLOW UP; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG NON SMALL CELL CANCER; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE PERIOD; PROTEIN EXPRESSION; SURVIVAL TIME; TUMOR DIFFERENTIATION;

AGED; CARCINOMA, NON-SMALL-CELL LUNG; FEMALE; FOLLOW-UP STUDIES; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; INHIBITOR OF APOPTOSIS PROTEINS; KAPLAN-MEIER ESTIMATE; LUNG NEOPLASMS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM STAGING; PROGNOSIS; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 84860724888     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2012.840     Document Type: Article

References (30)

1. Ferlay J, Shin HR, Bray F, Forman D, Mathers C and Parkin DM: Estimates of worldwide burden of cancer in 2008. GLOBOCAN 2008. Int J Cancer 127: 2893-2917, 2010.
2. Sato M, Shames DS, Gazdar AF and Minna JD: A translational view of the molecular pathogenesis of lung cancer. J Thorac Oncol 2: 327-343, 2007. (Pubitemid 47181718)
3. Yang Y, Zhu J, Gou H, Cao D, Jiang M and Hou M: Clinical significance of Cox-2, survivin and Bcl-2 expression in hepatocellular carcinoma (HCC). Med Oncol 28: 796-803, 2011.
4. Athanassiadou AM, Patsouris E, Tsipis A, Gonidi M and Athanassiadou P: The significance of survivin and Nectin-4 expression in the prognosis of breast carcinoma. Folia Histochem Cytobiol 49: 26-33, 2011.
5. Gan XL, Li JK, Yu TH, Zhang Y and Hu LN: High expressions of bcl-2 and survivin, and decreased apoptosis in uterine cervical carcinosarcoma compared to cervical squamous cell carcinoma. Arch Gynecol Obstet 284: 175-181, 2011.
6. Naruke T: Results of resected lung cancer based on the new UICC TNM classification, 5th edition. Gan To Kagaku Ryoho 24: 2289-2295, 1997.
7. Travis WD, Brambilla E, Muller-Hermelink HK and Harris CC (eds.): World Health Organization Classification of Tumours Pathology and Genetics of Tumours of the Lung, Pleura and Heart. IARC Press, Lyon, 2004.
8. Sinicrope FA, Ruan SB, Cleary KR, Stephens LC, Lee JJ and Levin B: bcl-2 and p53 oncoprotein expression during colorectal tumorigenesis. Cancer Res 55: 237-241, 1995.
9. Shivapurkar N, Reddy J, Chaudhary PM and Gazdar AF: Apoptosis and lung cancer: a review. J Cell Biochem 88: 885-898, 2003. (Pubitemid 36337033)
10. Xu CX, Jin H and Cho MH: Apoptosis and apoptosis-based therapy in lung cancer. Anticancer Agents Med Chem 9: 952-957, 2009.
11. Hengartner MO: The biochemistry of apoptosis. Nature 407: 770-776, 2000.
12. Ambrosini G, Adida C and Altieri DC: A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat Med 3: 917-921, 1997. (Pubitemid 27353455)
13. Youssef NS, Hewedi IH and Abd Raboh NM: Immunohistochemical expression of survivin in breast carcinoma relationship with clinicopathological parameters, proliferation and molecular classification. J Egypt Natl Canc Inst 20: 348-357, 2008.
14. Kalliakmanis JG, Kouvidou Ch, Latoufis C, et al: survivin expression in colorectal carcinomas: correlations with clinicopathological parameters and survival. Dig Dis Sci 55: 2958-2964, 2010.
15. Monzó M, Rosell R, Felip E, et al: A novel anti-apoptosis gene: Re-expression of survivin messenger RNA as a prognosis marker in non-small-cell lung cancers. J Clin Oncol 17: 2100-2104, 1999. (Pubitemid 29318841)
16. Hofmann HS, Simm A, Hammer A, Silber RE and Bartling B: Expression of inhibitors of apoptosis (IAP) proteins in non-small cell human lung cancer. J Cancer Res Clin Oncol 128: 554-560, 2002. (Pubitemid 35244931)
17. Ikehara M, Oshita F, Kameda Y, et al: Expression of survivin correlated with vessel invasion is a marker of poor prognosis in small adenocarcinoma of the lung. Oncol Rep 9: 835-838, 2002.
18. Tsujimoto Y, Gorham J, Cossman J, Jaffe E and Croce CM: The t(14;18)chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining. Science 229: 1390-1393, 1985. (Pubitemid 16222379)
19. Llambi F and Green DR: Apoptosis and oncogenesis: give and take in the BCL-2 family. Curr Opin Genet Dev 21: 12-20, 2011.
20. Brambilla E and Gazdar A: Pathogenesis of lung cancer signalling pathways: roadmap for therapies. Eur Respir J 33: 1485-1497, 2009.
21. Wang DF, Zeng CG, Lin YB, Hou JH and Zhu ZH: Expression and clinical significance of apoptosis-related oncogenes in stage I-II non-small cell lung cancer. Ai Zheng 25: 359-362, 2006.
22. Shibata Y, Hidaka S, Tagawa Y and Nagayasu T: Bcl-2 protein expression correlates with better prognosis in patients with advanced non-small cell lung cancer. Anticancer Res 24: 1925-1928, 2004. (Pubitemid 38954611)
23. Al-Joudi FS, Iskandar ZA and Imran AK: Correlations in survivin expression with the expression of p53 and bcl-2 in invasive ductal carcinoma of the breast. Southeast Asian J Trop Med Public Health 38: 904-910, 2007.
24. Han PH, Li XJ, Qin H, Yao J, DU N and Ren H: Upregulation of survivin in non-small cell lung cancer and its clinicopathological correlation with p53 and Bcl-2. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 25: 710-713, 2009.
25. Chen ZX and Pervaiz S: Involvement of cytochrome c oxidase subunits Va and Vb in the regulation of cancer cell metabolism by Bcl-2. Cell Death Differ 17: 408-420, 2010.
26. Altieri DC: New wirings in the survivin networks. Oncogene 27: 6276-6284, 2008.
27. Kaur P, Kallakury BS, Sheehan CE, Fisher HA, Kaufman RP Jr and Ross JS: survivin and Bcl-2 expression in prostatic adenocarcinomas. Arch Pathol Lab Med 128: 39-43, 2004. (Pubitemid 38049564)
28. Jeong IG, Kim SH, Jeon HG, Kim BH, Moon KC, Lee SE and Lee E: Prognostic value of apoptosis-related markers in urothelial cancer of the upper urinary tract. Hum Pathol 40: 666-677, 2009.
29. Zhu H, Hu Y, Shuai CX, Shi ZZ and Zhang HX: Expression of survivin, bcl-2 in cervical carcinoma and its association with HPV16/18 infection. Zhonghua Yi Xue Za Zhi 90: 469-473, 2010.
30. Kren L, Brazdil J, Hermanova M, Goncharuk VN, Kallakury BV, Kaur P and Ross JS: Prognostic significance of anti-apoptosis proteins survivin and bcl-2 in non-small cell lung carcinomas: a clinicopathologic study of 102 cases. Appl Immunohistochem Mol Morphol 12: 44-49, 2004. (Pubitemid 38332319)