Reversal of P-glycoprotein-mediated multidrug resistance in human hepatoma cells by hedyotiscone A, a compound isolated from Hedyotis corymbosa

Xenobiotica

Volumn 42, Issue 6, 2012, Pages 562-570

  Yue, Grace Gar Lee ^a,b   Lee, Julia Kin Ming ^a,b   Cheng, Ling ^a,b   Chan, Ben Chung Lap ^a,b   Jiang, Lei ^a,b   Fung, Kwok Pui ^a,b   Leung, Ping Chung ^a,b   Lau, Clara Bik San ^a,b  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b State Key Laboratory of Phytochemistry and Plant Resources in West China   (Hong Kong)

Author keywords

antitumor; apoptosis; Hedyotis corymbosa; Hedyotiscone A; multidrug resistance; P glycoprotein; R HepG2

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CASPASE 3; CASPASE 7; CASPASE 9; DNA; GLYCOPROTEIN P; HEDYOTISCONE A; MESSENGER RNA; PLANT MEDICINAL PRODUCT; THYMIDINE; UNCLASSIFIED DRUG;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CARCINOMA CELL; CELL PROLIFERATION; CONTROLLED STUDY; DNA FRAGMENTATION; ENZYME ACTIVATION; HEDYOTIS CORYMBOSA; HEPATOMA CELL; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; MEDICINAL PLANT; MULTIDRUG RESISTANCE; PROTEIN CLEAVAGE; PROTEIN EXPRESSION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL PROLIFERATION; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; HEDYOTIS; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; P-GLYCOPROTEIN; PHYTOTHERAPY; PSORALENS;

HEDYOTIS DIFFUSA; OLDENLANDIA CORYMBOSA; RUBIACEAE;

EID: 84860583029     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.3109/00498254.2011.645516     Document Type: Article

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