The effect of DISC1 on regional gray matter density of schizophrenia in Han Chinese population

Neuroscience Letters

Volumn 517, Issue 1, 2012, Pages 21-24

  Wei, Qinling ^a,b   Diao, Feici ^a   Kang, Zhuang ^a   Gan, Zhaoyu ^a   Han, Zili ^a   Zheng, Liangrong ^a   Li, Leijun ^a   Guo, Xiaofeng ^b   Shan, Baoci ^c   Liu, Chunlei ^d   Zhao, Jingping ^b   Zhang, Jinbei ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

^c INSTITUTE OF HIGH ENERGY PHYSICS   (China)

^d DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

DISC1; Gray matter; Magnetic resonance imaging; Schizophrenia

Indexed keywords

DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN;

ADULT; ALLELE; ARTICLE; BRAIN REGION; CHINESE; CONTROLLED STUDY; DENSITY; FEMALE; GENETIC VARIABILITY; GENOTYPE; GRAY MATTER; HETEROZYGOTE; HOMOZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; ORBITAL CORTEX; PARAHIPPOCAMPAL GYRUS; PRIORITY JOURNAL; RISK FACTOR; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; BRAIN; BRAIN MAPPING; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; NERVE TISSUE PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; SCHIZOPHRENIA; YOUNG ADULT;

EID: 84860567082     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2012.03.098     Document Type: Article

References (41)

1. Agarwal N., Port J.D., Bazzocchi M., Renshaw P.F. Update on the use of MR for assessment and diagnosis of psychiatric diseases. Radiology 2010, 255:23-41.
2. Ayhan Y., Abazyan B., Nomura J., Kim R., Ladenheim B., Krasnova I.N., Sawa A., Margolis R.L., Cadet J.L., Mori S., Vogel M.W., Ross C.A., Pletnikov M.V. Differential effects of prenatal and postnatal expressions of mutant human DISC1 on neurobehavioral phenotypes in transgenic mice: evidence for neurodevelopmental origin of major psychiatric disorders. Molecular Psychiatry 2011, 16:293-306.
3. Boos H.B., Aleman A., Cahn W., Hulshoff P.H., Kahn R.S. Brain volumes in relatives of patients with schizophrenia: a meta-analysis. Archives of General Psychiatry 2007, 64:297-304.
4. Boos H.B., Cahn W., van Haren N.E., Derks E.M., Brouwer R.M., Schnack H.G., Hulshoff P.H., Kahn R.S. Focal and global brain measurements in siblings of patients with schizophrenia. Schizophrenia Bulletin 2011.
5. Bradshaw N.J., Porteous D.J. DISC1-binding proteins in neural development, signalling and schizophrenia. Neuropharmacology 2010.
6. Brauns S., Gollub R.L., Roffman J.L., Yendiki A., Ho B.C., Wassink T.H., Heinz A., Ehrlich S. DISC1 is associated with cortical thickness and neural efficiency. Neuroimage 2011, 57:1591-1600.
7. Callicott J.H., Straub R.E., Pezawas L., Egan M.F., Mattay V.S., Hariri A.R., Verchinski B.A., Meyer-Lindenberg A., Balkissoon R., Kolachana B., Goldberg T.E., Weinberger D.R. Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia. Proceedings of the National Academy of Sciences of the United States of America 2005, 102:8627-8632.
8. Carless M.A., Glahn D.C., Johnson M.P., Curran J.E., Bozaoglu K., Dyer T.D., Winkler A.M., Cole S.A., Almasy L., Maccluer J.W., Duggirala R., Moses E.K., Goring H.H., Blangero J. Impact of DISC1 variation on neuroanatomical and neurocognitive phenotypes. Molecular Psychiatry 2011, 16:1096-1104.
9. Chakirova G., Welch K.A., Moorhead T.W., Stanfield A.C., Hall J., Skehel P., Brown V.J., Johnstone E.C., Owens D.G., Lawrie S.M., McIntosh A.M. Orbitofrontal morphology in people at high risk of developing schizophrenia. European Psychiatry 2010, 25:366-372.
10. Di Giorgio A., Blasi G., Sambataro F., Rampino A., Papazacharias A., Gambi F., Romano R., Caforio G., Rizzo M., Latorre V., Popolizio T., Kolachana B., Callicott J.H., Nardini M., Weinberger D.R., Bertolino A. Association of the SerCys DISC1 polymorphism with human hippocampal formation gray matter and function during memory encoding. European Journal of Neuroscience 2008, 28:2129-2136.
11. Ekelund J., Hovatta I., Parker A., Paunio T., Varilo T., Martin R., Suhonen J., Ellonen P., Chan G., Sinsheimer J.S., Sobel E., Juvonen H., Arajarvi R., Partonen T., Suvisaari J., Lonnqvist J., Meyer J., Peltonen L. Chromosome 1 loci in Finnish schizophrenia families. Human Molecular Genetics 2001, 10:1611-1617.
12. Glahn D.C., Laird A.R., Ellison-Wright I., Thelen S.M., Robinson J.L., Lancaster J.L., Bullmore E., Fox P.T. Meta-analysis of gray matter anomalies in schizophrenia: application of anatomic likelihood estimation and network analysis. Biological Psychiatry 2008, 64:774-781.
13. Hashimoto R., Numakawa T., Ohnishi T., Kumamaru E., Yagasaki Y., Ishimoto T., Mori T., Nemoto K., Adachi N., Izumi A., Chiba S., Noguchi H., Suzuki T., Iwata N., Ozaki N., Taguchi T., Kamiya A., Kosuga A., Tatsumi M., Kamijima K., Weinberger D.R., Sawa A., Kunugi H. Impact of the DISC1 Ser704Cys polymorphism on risk for major depression, brain morphology and ERK signaling. Human Molecular Genetics 2006, 15:3024-3033.
14. Hodgkinson C.A., Goldman D., Jaeger J., Persaud S., Kane J.M., Lipsky R.H., Malhotra A.K. Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder. American Journal of Human Biology 2004, 75:862-872.
15. Insel T.R. Rethinking schizophrenia. Nature 2010, 468:187-193.
16. Ishizuka K., Kamiya A., Oh E.C., Kanki H., Seshadri S., Robinson J.F., Murdoch H., Dunlop A.J., Kubo K., Furukori K., Huang B., Zeledon M., Hayashi-Takagi A., Okano H., Nakajima K., Houslay M.D., Katsanis N., Sawa A. DISC1-dependent switch from progenitor proliferation to migration in the developing cortex. Nature 2011, 473:92-96.
17. Jaaro-Peled H., Hayashi-Takagi A., Seshadri S., Kamiya A., Brandon N.J., Sawa A. Neurodevelopmental mechanisms of schizophrenia: understanding disturbed postnatal brain maturation through neuregulin-1-ErbB4 and DISC1. Trends in Neurosciences 2009, 32:485-495.
18. Johnstone M., Thomson P.A., Hall J., McIntosh A.M., Lawrie S.M., Porteous D.J. DISC1 in schizophrenia: genetic mouse models and human genomic imaging. Schizophrenia Bulletin 2011, 37:14-20.
19. Jung Y.C., Park H.J., Kim J.J., Chun J.W., Kim H.S., Kim N.W., Son S.J., Oh M.G., Lee J.D. Reciprocal activation of the orbitofrontal cortex and the ventrolateral prefrontal cortex in processing ambivalent stimuli. Brain Research 2008, 1246:136-143.
20. Kringelbach M.L The human orbitofrontal cortex: linking reward to hedonic experience. Nature Reviews Neuroscience 2005, 6:691-702.
21. Lang U.E., Puls I., Muller D.J., Strutz-Seebohm N., Gallinat J. Molecular mechanisms of schizophrenia. Cellular Physiology and Biochemistry 2007, 20:687-702.
22. Lencz T., Szeszko P.R., DeRosse P., Burdick K.E., Bromet E.J., Bilder R.M., Malhotra A.K. A schizophrenia risk gene ZNF804A, influences neuroanatomical and neurocognitive phenotypes. Neuropsychopharmacol 2010, 35:2284-2291.
23. Ming G.L., Song H. DISC1 partners with GSK3beta in neurogenesis. Cell 2009, 136:990-992.
24. Moens L.N., De Rijk P., Reumers J., Van den Bossche M.J., Glassee W., De Zutter S., Lenaerts A.S., Nordin A., Nilsson L.G., Medina C.I., Norrback K.F., Goossens D., Van Steen K., Adolfsson R., Del-Favero J. Sequencing of DISC1 pathway genes reveals increased burden of rare missense variants in schizophrenia patients from a northern Swedish population. PLoS One 2011, 6:e23450.
25. Muir W.J., Pickard B.S., Blackwood D.H. Disrupted-in-schizophrenia-1. Current Psychiatry Reports 2008, 10:140-147.
26. Ohnishi T., Hashimoto R., Mori T., Nemoto K., Moriguchi Y., Iida H., Noguchi H., Nakabayashi T., Hori H., Ohmori M., Tsukue R., Anami K., Hirabayashi N., Harada S., Arima K., Saitoh O., Kunugi H. The association between the Val158Met polymorphism of the catechol-O-methyl transferase gene and morphological abnormalities of the brain in chronic schizophrenia. Brain 2006, 129:399-410.
27. Oldfield R.C The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia 1971, 9:97-113.
28. Ongur D., Price J.L. The organization of networks within the orbital and medial prefrontal cortex of rats, monkeys and humans. Cerebral Cortex 2000, 10:206-219.
29. Qu M., Tang F., Yue W., Ruan Y., Lu T., Liu Z., Zhang H., Han Y., Zhang D., Wang F., Zhang D. Positive association of the disrupted-in-schizophrenia-1 gene (DISC1) with schizophrenia in the Chinese Han population. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics 2007, 144B:266-270.
30. Raznahan A., Lee Y., Long R., Greenstein D., Clasen L., Addington A., Rapoport J.L., Giedd J.N. Common functional polymorphisms of DISC1 and cortical maturation in typically developing children and adolescents. Molecular Psychiatry 2011, 16:917-926.
31. Sawamura N., Sawamura-Yamamoto T., Ozeki Y., Ross C.A., Sawa A. A form of DISC1 enriched in nucleus: altered subcellular distribution in orbitofrontal cortex in psychosis and substance/alcohol abuse. Proceedings of the National Academy of Sciences of the United States of America 2005, 102:1187-1192.
32. Schultz C.C., Koch K., Wagner G., Roebel M., Nenadic I., Gaser C., Schachtzabel C., Reichenbach J.R., Sauer H., Schlosser R.G. Increased parahippocampal and lingual gyrification in first-episode schizophrenia. Schizophrenia Research 2010, 123:137-144.
33. St C.D., Blackwood D., Muir W., Carothers A., Walker M., Spowart G., Gosden C., Evans H.J. Association within a family of a balanced autosomal translocation with major mental illness. Lancet 1990, 336:13-16.
34. Szeszko P.R., Hodgkinson C.A., Robinson D.G., Derosse P., Bilder R.M., Lencz T., Burdick K.E., Napolitano B., Betensky J.D., Kane J.M., Goldman D., Malhotra A.K. DISC1 is associated with prefrontal cortical gray matter and positive symptoms in schizophrenia. Biological Psychiatry 2008, 79:103-110.
35. Takahashi T., Suzuki M., Tsunoda M., Maeno N., Kawasaki Y., Zhou S.Y., Hagino H., Niu L., Tsuneki H., Kobayashi S., Sasaoka T., Seto H., Kurachi M., Ozaki N. The disrupted-in-schizophrenia-1 Ser704Cys polymorphism and brain morphology in schizophrenia. Psychiatry Research 2009, 172:128-135.
36. Takayanagi Y., Takahashi T., Orikabe L., Masuda N., Mozue Y., Nakamura K., Kawasaki Y., Itokawa M., Sato Y., Yamasue H., Kasai K., Okazaki Y., Suzuki M. Volume reduction and altered sulco-gyral pattern of the orbitofrontal cortex in first-episode schizophrenia. Schizophrenia Research 2010, 121:55-65.
37. van Haren N.E., Schnack H.G., Cahn W., van den Heuvel M.P., Lepage C., Collins L., Evans A.C., Hulshoff P.H., Kahn R.S. Changes in cortical thickness during the course of illness in schizophrenia. Archives of General Psychiatry 2011, 68:871-880.
38. Walton M.E., Devlin J.T., Rushworth M.F. Interactions between decision making and performance monitoring within prefrontal cortex. Nature Neuroscience 2004, 7:1259-1265.
39. Wang Q., Brandon N.J. Regulation of the cytoskeleton by disrupted-in-schizophrenia 1 (DISC1). Molecular and Cellular Neuroscience 2011, 48:359-364.
40. Wei Q., Kang Z., Diao F., Shan B., Li L., Zheng L., Guo X., Liu C., Zhang J., Zhao J. Association of the ZNF804A gene polymorphism rs1344706 with white matter density changes in Chinese schizophrenia. Progress in Neuropsychopharmacol Biological Psychiatry 2012, 36:122-127.
41. Yang Y., Nuechterlein K.H., Phillips O., Hamilton L.S., Subotnik K.L., Asarnow R.F., Toga A.W., Narr K.L. The contributions of disease and genetic factors towards regional cortical thinning in schizophrenia: the UCLA family study. Schizophrenia Research 2010, 123:116-125.