New advances in juvenile spondyloarthritis

Nature Reviews Rheumatology

Volumn 8, Issue 5, 2012, Pages 269-279

  Tse, Shirley M L ^a   Laxer, Ronald M ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADALIMUMAB; CORTICOSTEROID; ETANERCEPT; INFLIXIMAB; METHOTREXATE; NONSTEROID ANTIINFLAMMATORY AGENT; PLACEBO; SALAZOSULFAPYRIDINE; STEROID;

ABSENCE OF SIDE EFFECTS; CLINICAL FEATURE; DISEASE ACTIVITY; DISEASE ASSOCIATION; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; ERAP1 GENE; GENE; GENETIC ASSOCIATION; HUMAN; IMAGE ANALYSIS; INTERLEUKIN 23 RECEPTOR GENE; JUVENILE SPONDYLOARTHRITIS; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROGNOSIS; QUALITY OF LIFE; RECEPTOR GENE; REVIEW; SPONDYLARTHRITIS; SYNDROME DELINEATION; TREATMENT PLANNING; UNSPECIFIED SIDE EFFECT;

ADOLESCENT; ADULT; AGE FACTORS; AGE OF ONSET; BIOLOGICAL AGENTS; CHILD; COMBINED MODALITY THERAPY; DIAGNOSTIC IMAGING; DISEASE PROGRESSION; EARLY DIAGNOSIS; FEMALE; FORECASTING; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MONITORING, PHYSIOLOGIC; PRACTICE GUIDELINES AS TOPIC; PROGNOSIS; RADIOGRAPHIC IMAGE ENHANCEMENT; RECURRENCE; RISK ASSESSMENT; SACROILIAC JOINT; SPONDYLARTHRITIS; SPONDYLITIS, ANKYLOSING; TUMOR NECROSIS FACTOR-ALPHA; ULTRASONOGRAPHY, DOPPLER; WHOLE BODY IMAGING; YOUNG ADULT;

EID: 84860565967     PISSN: 17594790     EISSN: 17594804     Source Type: Journal    
DOI: 10.1038/nrrheum.2012.37     Document Type: Review

References (87)

1. Burgos-Vargas, R. The juvenile-onset spondyloarthritides. Rheum. Dis. Clin. North Am. 28, 531-560 (2002)
2. van Tubergen, A. & Weber, U. Diagnosis and classification in spondyloarthritis: Identifying a chameleon. Nat. Rev. Rheumatol. 8, 253-261 (2012)
3. Lin, Y. C., Liang, T. H., Chen, W. S. & Lin, H. Y. Differences between juvenile-onset ankylosing spondylitis and adult-onset ankylosing spondylitis. J. Chin. Med. Assoc. 72, 573-580 (2009)
4. O'Shea, F. D. et al. Comparison of clinical and radiographic severity of juvenile-onset versus adult-onset ankylosing spondylitis. Ann. Rheum. Dis. 68, 1407-1412 (2009)
5. Baek, H. J. et al. Juvenile onset ankylosing spondylitis (JAS) has less severe spinal disease course than adult onset ankylosing spondylitis (AAS): Clinical comparison between JAS and AAS in Korea. J. Rheumatol. 29, 1780-1785 (2002)
6. van Der Linden, S., Valkenburg, H. A. & Cats, A. Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria. Arthritis Rheum. 27, 361-368 (1984)
7. Rudwaleit, M. et al. The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part II): Validation and final selection. Ann. Rheum. Dis. 68, 777-783 (2009)
8. Kleinman, P., Rivelis, M., Schneider, R. & Kaye, J. J. Juvenile ankylosing spondylitis. Radiology 125, 775-780 (1977)
9. Amor, B., Dougados, M. & Mijiyawa, M. Criteria of the classification of spondylarthropathies [French]. Rev. Rhum. Mal. Osteoartic. 57, 85-89 (1990)
10. Amor, B. et al. Evaluation of the Amor criteria for spondylarthropathies and European Spondylarthropathy Study Group (ESSG). A cross-sectional analysis of 2,228 patients [French]. Ann. Med. Interne (Paris) 142, 85-89 (1991)
11. Amor, B. In 50 ans De Rhumatologie et l'avenir 29-31 (Expanscience, Courbevoie, 2005)
12. Dougados, M. et al. The European Spondylarthropathy Study Group preliminary criteria for the classification of spondylarthropathy. Arthritis Rheum. 34, 1218-1227 (1991)
13. Rudwaleit, M. et al. The Assessment of SpondyloArthritis International Society classification criteria for peripheral spondyloarthritis and for spondyloarthritis in general. Ann. Rheum. Dis. 70, 25-31 (2011)
14. Rosenberg, A, M. & Petty, R. E. A syndrome of seronegatvie enthesopathy and arthropathy in children. Arthritis Rheum. 25, 1041-1047 (1982)
15. Hafner, R. Juvenile spondarthritis. Retrospective study of 71 patients [German]. Monatsschr. Kinderheilkd. 135, 41-46 (1987)
16. Hussein, A., Abdul-Khaliq, H. & von Der Hardt, H. Atypical spondyloarthritis in children: Proposed diagnostic criteria. 148, 513-517 (1989)
17. Petty, R. E. et al. Revision of the proposed classification criteria for juvenile idiopathic arthritis: Durban, 1997. J. Rheumatol. 25, 1991-1994 (1998)
18. Petty, R. E. et al. International League of Associations for Rheumatology classification of juvenile idiopathic arthritis: Second revision, Edmonton, 2001. J. Rheumatol. 31, 390-392 (2004)
19. Prieur, A. M. Spondyloarthropathies in childhood. Baillieres Clin. Rheumatol. 12, 287-307 (1998)
20. Prieur, A. M. Spondylarthropathies in children. Ann. Med. Interne (Paris) 149, 156-158 (1998)
21. Kasapcopur, O. et al. Evaluation of classification criteria for juvenile-onset spondyloarthropathies. Rheumatol. Int. 25, 414-418 (2005)
22. Joos, R. et al. Sensitivity and specificity of criteria for spondyloarthritis in children with late onset pauciarticular juvenile chronic arthritis as well as their characteristics. Clin. Exp. Rheumatol. 27, 870-876 (2009)
23. Burgos-Vargas, R., Pacheco-Tena, C. & Vazquez-Mellado, J. Juvenile-onset spondyloarthropathies. Rheum. Dis. Clin. North Am. 23, 569-598 (1997)
24. Alvarez-Madrid, C., Merino, R., De Inocencio, J. & Garcia-Consuegra, J. Tarsitis as an initial manifestation of juvenile spondyloarthropathy. Clin. Exp. Rheumatol. 27, 691-694 (2009)
25. Petty, R., Cassidy, J. T. in Textbook of Pediatric Rheumatology (eds Cassidy, J. T., Petty, R, Laxer, R. & Lindsley, C.) 272-286 (Elsevier, Amsterdam, 2011)
26. Burgos-Vargas, R. & Vazquez-Mellado, J. The early clinical recognition of juvenile-onset ankylosing spondylitis and its differentiation from juvenile rheumatoid arthritis. Arthritis Rheum. 38, 835-844 (1995)
27. Burgos-Vargas, R. & Clark, P. Axial involvement in the seronegative enthesopathy and arthropathy syndrome and its progression to ankylosing spondylitis. J. Rheumatol. 16, 192-197 (1989)
28. Cabral, D. A., Oen, K. G. & Petty, R. E. SEA syndrome revisited: A longterm followup of children with a syndrome of seronegative enthesopathy and arthropathy. J. Rheumatol. 19, 1282-1285 (1992)
29. Flato, B. et al. Long-term outcome and prognostic factors in enthesitis-related arthritis: A case-control study. Arthritis Rheum. 54, 3573-3582 (2006)
30. Minden, K. et al. Long-term outcome in patients with juvenile idiopathic arthritis. Arthritis Rheum. 46, 2392-2401 (2002)
31. Burgos-Vargas, R. et al. Genuine ankylosing spondylitis in children: A case-control study of patients with early definite disease according to adult onset criteria. J. Rheumatol. 23, 2140-2147 (1996)
32. Burgos-Vargas, R., Lardizabal-Sanabria, J. & Katona, G. Anterior spinal flexion in healthy Mexican children. J. Rheumatol. 12, 123-125 (1985)
33. Weiss, P. F. et al. Enthesitis in an inception cohort of enthesitis-related arthritis. Arthritis Care Res. (Hoboken) 63, 1307-1312 (2011)
34. Mielants, H. et al. The evolution of spondyloarthropathies in relation to gut histology. II. Histological aspects. J. Rheumatol. 22, 2273-2278 (1995)
35. Mielants, H. et al. Gut inflammation in children with late onset pauciarticular juvenile chronic arthritis and evolution to adult spondyloarthropathy-A prospective study. J. Rheumatol. 20, 1567-1572 (1993)
36. Stoll, M. L. et al. Patients with juvenile psoriatic arthritis comprise two distinct populations. Arthritis Rheum. 54, 3564-3572 (2006)
37. Stamato, T. et al. Prevalence of cardiac manifestations of juvenile ankylosing spondylitis. Am. J. Cardiol. 75, 744-746 (1995)
38. Bollow, M. et al. Use of dynamic magnetic resonance imaging to detect sacroiliitis in HLA B27 positive and negative children with juvenile arthritides. J. Rheumatol. 25, 556-564 (1998)
39. Bollow, M. et al. Use of contrast-enhanced MR imaging to detect sacroiliitis in children. Skeletal Radiol. 27, 606-616 (1998)
40. Yilmaz, M. H., Ozbayrak, M., Kasapcopur, O., Kurugoglu, S. & Kanberoglu, K. Pelvic MRI findings of juvenile-onset ankylosing spondylitis. Clin. Rheumatol. 29, 1007-1013 (2010)
41. Rachlis, A. C. et al. Whole body MR imaging in juvenile spondyloarthritis: Will it provide vital information compared to clinical exam alone? [abstract]. Arthritis Rheum. 63, S292 (2011)
42. Jousse-Joulin, S. et al. Ultrasonography for detecting enthesitis in juvenile idiopathic arthritis. Arthritis Care Res. (Hoboken) 63, 849-855 (2011)
43. van Der Linden, S. M., Valkenburg, H. A., De Jongh, B. M. & Cats, A. The risk of developing ankylosing spondylitis in HLA B27 positive individuals. A comparison of relatives of spondylitis patients with the general population. Arthritis Rheum. 27, 241-249 (1984)
44. Reveille, J. D. Genetic basis of spondyloarthritis-beyond the MHC. Nat. Rev. Rheumatol. 8, 296-304 (2012)
45. Stanevicha, V. et al. HLA B27 allele types in homogeneous groups of juvenile idiopathic arthritis patients in Latvia. Pediatr. Rheumatol. Online J. 8, 26 (2010)
46. Hinks, A. et al. Subtype specific genetic associations for juvenile idiopathic arthritis: ERAP1 with the enthesitis related arthritis subtype and IL23R with juvenile psoriatic arthritis. Arthritis. Res. Ther. 13, R12 (2011)
47. Wanders, A. et al. Nonsteroidal antiinflammatory drugs reduce radiographic progression in patients with ankylosing spondylitis: A randomized clinical trial. Arthritis Rheum. 52, 1756-1765 (2005)
48. Jarrett, S. J. et al. MRI and clinical findings in patients with ankylosing spondylitis eligible for anti-tumour necrosis factor therapy after a short course of etoricoxib. Ann. Rheum. Dis. 68, 1466-1469 (2009)
49. Burgos-Vargas, R., Vazquez-Mellado, J., Pacheco-Tena, C., Hernandez-Garduno, A. & Goycochea-Robles, M. V. A 26 week randomised, double blind, placebo controlled exploratory study of sulfasalazine in juvenile onset spondyloarthropathies. Ann. Rheum. Dis. 61, 941-942 (2002)
50. van Rossum, M. A. et al. Sulfasalazine in the treatment of juvenile chronic arthritis: A randomized, double-blind, placebo-controlled, multicenter study. Dutch Juvenile Chronic Arthritis Study Group. Arthritis Rheum. 41, 808-816 (1998)
51. Imundo, L. F. & Jacobs, J. C. Sulfasalazine therapy for juvenile rheumatoid arthritis. J. Rheumatol. 23, 360-366 (1996)
52. Suschke, H. J. Treatment of juvenile spondylarthritis and reactive arthritis with sulfasalazine [German]. Monatsschr. Kinderheilkd. 140, 658-660 (1992)
53. Job-Deslandre, C. & Menkes, C. J. Treatment of juvenile spondyloarthropathies with sulfasalazine [French]. Rev. Rhum. Ed. Fr. 60, 489-491 (1993)
54. Huang, J. L. & Chen, L. C. Sulphasalazine in the treatment of children with chronic arthritis. Clin. Rheumatol. 17, 359-363 (1998)
55. Woo, P. et al. Randomized, placebo-controlled, crossover trial of low-dose oral methotrexate in children with extended oligoarticular or systemic arthritis. Arthritis Rheum. 43, 1849-1857 (2000)
56. Ruperto, N. et al. A randomized trial of parenteral methotrexate comparing an intermediate dose with a higher dose in children with juvenile idiopathic arthritis who failed to respond to standard doses of methotrexate. Arthritis Rheum. 50, 2191-2201 (2004)
57. Giannini, E. H. et al. Methotrexate in resistant juvenile rheumatoid arthritis. Results of the USA USSR double-blind, placebo-controlled trial. The Pediatric Rheumatology Collaborative Study Group and The Cooperative Children's Study Group. N. Engl. J. Med. 326, 1043-1049 (1992)
58. Burgos-Vargas, R. Efficacy, safety, and tolerability of Infliximab in Juvenile-onset Spondyloarthropathies (JO-SpA): Results of the three-month, randomized, double-blind, placebo-controlled trial phase [abstract]. Arthritis Rheum. 56, S319 (2007)
59. Burgos-Vargas, R., Casasola Vargas, J. & Gutierrez-Suarez, R. A 3 month, double-blind, placebo-controlled, randomized trial of infliximab in juvenile-onset spondyloarthritis (SpA) and a 52-week open extension. Clin. Exp. Rheumatol. 26, 745 (2008)
60. Henrickson, M. & Reiff, A. Prolonged efficacy of etanercept in refractory enthesitis-related arthritis. J. Rheumatol. 31, 2055-2061 (2004)
61. Tse, S. M., Burgos-Vargas, R. & Laxer, R. M. Anti-tumor necrosis factor alpha blockade in the treatment of juvenile spondylarthropathy. Arthritis Rheum. 52, 2103-2108 (2005)
62. Tse, S. M. L, Burgos Vargas, R., O'Shea F, Inman, R. & Laxer, R. Long term outcome of anti-TNF therapy in juvenile spondyloarthropathy. Arthritis Rheum. 56, 898 (2007)
63. Tse, S. M., Laxer, R. M., Babyn, P. S. & Doria, A. S. Radiologic Improvement of juvenile idiopathic arthritis enthesitis related arthritis following anti-tumor necrosis factor-Alpha blockade with etanercept. J. Rheumatol. 33, 1186-1188 (2006)
64. Sulpice, M., Deslandre, C. J. & Quartier, P. Efficacy and safety of TNFalpha antagonist therapy in patients with juvenile spondyloarthropathies. Joint Bone Spine 76, 24-27 (2009)
65. Schmeling, H. & Horneff, G. Infliximab in two patients with juvenile ankylosing spondylitis. Rheumatol. Int. 24, 173-176 (2004)
66. Otten, M. H. et al. Tumor necrosis factor-blocking agents for children with enthesitis-related arthritis data from the Dutch Arthritis and Biologicals in Children Register, 1999-2010. J. Rheumatol. 38, 2258-2263 (2011)
67. Beukelman, T. et al. 2011 American College of Rheumatology recommendations for the treatment of juvenile idiopathic arthritis: Initiation and safety monitoring of therapeutic agents for the treatment of arthritis and systemic features. Arthritis Care Res. (Hoboken) 63, 465-482 (2011)
68. Flato, B. et al. The influence of patient characteristics, disease variables, and HLA alleles on the development of radiographically evident sacroiliitis in juvenile idiopathic arthritis. Arthritis Rheum. 46, 986-994 (2002)
69. Bennett, A. N. et al. Severity of baseline magnetic resonance imaging-evident sacroiliitis and HLA B27 status in early inflammatory back pain predict radiographically evident ankylosing spondylitis at eight years. Arthritis Rheum. 58, 3413-3418 (2008)
70. Braun, J. et al. 2010 update of the ASAS/EULAR recommendations for the management of ankylosing spondylitis. Ann. Rheum. Dis. 70, 896-904 (2011)
71. van Der Heijde, D. et al. 2010 Update of the international ASAS recommendations for the use of anti-TNF agents in patients with axial spondyloarthritis. Ann. Rheum. Dis. 70, 905-908 (2011)
72. Sieper, J. Developments in therapies for spondyloarthritis. Nat. Rev. Rheumatol. 8, 280-287 (2012)
73. Batthish, M. R. A. et al. Intra-rater Reliability of the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and the Bath Ankylosing Spondylitis Functional Index (BASFI) in Children with Spondyloarthritis [abstract]. Arthritis Rheum. 62, S95 (2010)
74. Maksymowych, W. P. et al. The Canadian Rheumatology Association/ Spondyloarthritis Research Consortium of Canada treatment recommendations for the management of spondyloarthritis: A national multidisciplinary stakeholder project. J. Rheumatol. 34, 2273-2284 (2007)
75. Minden, K. et al. Prognosis of patients with juvenile chronic arthritis and juvenile spondyloarthropathy. J. Rheumatol. 27, 2256-2263 (2000)
76. Flato, B., Aasland, A., Vinje, O. & Forre, O. Outcome and predictive factors in juvenile rheumatoid arthritis and juvenile spondyloarthropathy. J. Rheumatol. 25, 366-375 (1998)
77. Selvaag, A. M. et al. Early disease course and predictors of disability in juvenile rheumatoid arthritis and juvenile spondyloarthropathy: A 3 year prospective study. J. Rheumatol. 32, 1122-1130 (2005)
78. Sarma, P. K., Misra, R. & Aggarwal, A. Outcome in patients with enthesitis related arthritis (ERA): juvenile arthritis damage index (JADI) and functional status. Pediatr. Rheumatol. Online J. 6, 18 (2008)
79. Oen, K. et al. Early outcomes and improvement of patients with juvenile idiopathic arthritis enrolled in a Canadian multicenter inception cohort. Arthritis Care Res (Hoboken) 62, 527-536 (2010)
80. Oen, K. et al. Predictors of early inactive disease in a juvenile idiopathic arthritis cohort: Results of a Canadian multicenter, prospective inception cohort study. Arthritis Rheum. 61, 1077-1086 (2009)
81. Sieper, J., Braun, J., Rudwaleit, M., Boonen, A. & Zink, A. Ankylosing spondylitis: An overview. Ann. Rheum. Dis. 61 (Suppl. 3), iii8-iii18 (2002)
82. Calin, A. & Elswood, J. The natural history of juvenile-onset ankylosing spondylitis: A 24-year retrospective case-control study. Br. J. Rheumatol. 27, 91-93 (1988)
83. Stone, M. et al. Juvenile-onset ankylosing spondylitis is associated with worse functional outcomes than adult-onset ankylosing spondylitis. Arthritis Rheum. 53, 445-451 (2005)
84. Giannini, E. H. et al. Preliminary definition of improvement in juvenile arthritis. Arthritis Rheum. 40, 1202-1209 (1997)
85. Wallace, C. A., Ruperto, N. & Giannini, E. Preliminary criteria for clinical remission for select categories of juvenile idiopathic arthritis. J. Rheumatol. 31, 2290-2294 (2004)
86. Sieper, J. et al. The Assessment of SpondyloArthritis international Society (ASAS) handbook: A guide to assess spondyloarthritis. Ann. Rheum. Dis. 68 (Suppl. 2), ii1-ii44 (2009)
87. Thornton, J. et al. Costing juvenile idiopathic arthritis: Examining patient-based costs during the first year after diagnosis. Rh