-
1
-
-
0036305274
-
Clinical management of gastrointestinal stromal tumors: Before and after STI-571
-
Dematteo RP, Heinrich MC, El-Rifai WM, Demetri G. Clinical management of gastrointestinal stromal tumors: before and after STI-571. Hum Pathol. 2002; 33(5):466-477.
-
(2002)
Hum Pathol.
, vol.33
, Issue.5
, pp. 466-477
-
-
Dematteo, R.P.1
Heinrich, M.C.2
El-Rifai, W.M.3
Demetri, G.4
-
2
-
-
15644363454
-
Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors
-
Hirota S, Isozaki K, Moriyama Y, et al. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science. 1998;279(5350): 577-580.
-
(1998)
Science.
, vol.279
, Issue.5350
, pp. 577-580
-
-
Hirota, S.1
Isozaki, K.2
Moriyama, Y.3
-
3
-
-
0029947186
-
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
-
Druker BJ, Tamura S, Buchdunger E, et al. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat Med. 1996; 2(5):561-566.
-
(1996)
Nat Med.
, vol.2
, Issue.5
, pp. 561-566
-
-
Druker, B.J.1
Tamura, S.2
Buchdunger, E.3
-
4
-
-
0035810148
-
Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor
-
Joensuu H, Roberts PJ, Sarlomo-Rikala M, et al. Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor. N Engl J Med. 2001;344(14):1052-1056.
-
(2001)
N Engl J Med.
, vol.344
, Issue.14
, pp. 1052-1056
-
-
Joensuu, H.1
Roberts, P.J.2
Sarlomo-Rikala, M.3
-
5
-
-
0037103424
-
Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors
-
Demetri GD, von Mehren M, Blanke CD, et al. Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. N Engl J Med. 2002;347(7):472-480.
-
(2002)
N Engl J Med.
, vol.347
, Issue.7
, pp. 472-480
-
-
Demetri, G.D.1
Von Mehren, M.2
Blanke, C.D.3
-
6
-
-
0036795899
-
Approval summary: Imatinib mesylate in the treatment of metastatic and/or unresectable malignant gastrointestinal stromal tumors
-
Dagher R, Cohen M, Williams G, et al. Approval summary: imatinib mesylate in the treatment of metastatic and/or unresectable malignant gastrointestinal stromal tumors. Clin Cancer Res. 2002;8(10):3034-3038.
-
(2002)
Clin Cancer Res.
, vol.8
, Issue.10
, pp. 3034-3038
-
-
Dagher, R.1
Cohen, M.2
Williams, G.3
-
7
-
-
39149123549
-
Long-term results from a randomized phase II trial of standard-versus higher-dose imatinib mesylate for patients with unresectable or metastatic gastrointestinal stromal tumors expressing KIT
-
Blanke CD, Demetri GD, von Mehren M, et al. Long-term results from a randomized phase II trial of standard-versus higher-dose imatinib mesylate for patients with unresectable or metastatic gastrointestinal stromal tumors expressing KIT. J Clin Oncol. 2008;26(4):620-625.
-
(2008)
J Clin Oncol.
, vol.26
, Issue.4
, pp. 620-625
-
-
Blanke, C.D.1
Demetri, G.D.2
Von Mehren, M.3
-
8
-
-
39149127634
-
Phase III randomized, intergroup trial assessing imatinib mesylate at two dose levels in patients with unresectable or metastatic gastrointestinal stromal tumors expressing the kit receptor tyrosine kinase: S0033
-
Blanke CD, Rankin C, Demetri GD, et al. Phase III randomized, intergroup trial assessing imatinib mesylate at two dose levels in patients with unresectable or metastatic gastrointestinal stromal tumors expressing the kit receptor tyrosine kinase: S0033. J Clin Oncol. 2008;26(4):626-632.
-
(2008)
J Clin Oncol.
, vol.26
, Issue.4
, pp. 626-632
-
-
Blanke, C.D.1
Rankin, C.2
Demetri, G.D.3
-
9
-
-
20844433223
-
Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: Randomised trial
-
Verweij J, Casali PG, Zalcberg J, et al. Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: randomised trial. Lancet. 2004;364(9440):1127-1134.
-
(2004)
Lancet.
, vol.364
, Issue.9440
, pp. 1127-1134
-
-
Verweij, J.1
Casali, P.G.2
Zalcberg, J.3
-
10
-
-
0032862462
-
Gastrointestinal stromal tumors/smooth muscle tumors (GISTs) primary in the omentum and mesentery: Clinicopathologic and immunohistochemical study of 26 cases
-
Miettinen M, Monihan JM, Sarlomo-Rikala M, et al. Gastrointestinal stromal tumors/smooth muscle tumors (GISTs) primary in the omentum and mesentery: clinicopathologic and immunohistochemical study of 26 cases. Am J Surg Pathol. 1999;23(9):1109-1118.
-
(1999)
Am J Surg Pathol.
, vol.23
, Issue.9
, pp. 1109-1118
-
-
Miettinen, M.1
Monihan, J.M.2
Sarlomo-Rikala, M.3
-
11
-
-
70249089412
-
Gastrointestinal stromal tumors presenting as omental masses-A clinicopathologic analysis of 95 cases
-
Miettinen M, Sobin LH, Lasota J. Gastrointestinal stromal tumors presenting as omental masses-a clinicopathologic analysis of 95 cases. Am J Surg Pathol. 2009;33(9):1267-1275.
-
(2009)
Am J Surg Pathol.
, vol.33
, Issue.9
, pp. 1267-1275
-
-
Miettinen, M.1
Sobin, L.H.2
Lasota, J.3
-
12
-
-
77953079312
-
Primary extragastrointestinal stromal tumor of the pleura: Report of a unique case with genetic confirmation
-
Long KB, Butrynski JE, Blank SD, et al. Primary extragastrointestinal stromal tumor of the pleura: report of a unique case with genetic confirmation. Am J Surg Pathol. 2010;34(6):907-912.
-
(2010)
Am J Surg Pathol.
, vol.34
, Issue.6
, pp. 907-912
-
-
Long, K.B.1
Butrynski, J.E.2
Blank, S.D.3
-
14
-
-
3042646931
-
A great majority of GISTs with PDGFRA mutations represent gastric tumors of low or no malignant potential
-
Lasota J, Dansonka-Mieszkowska A, Sobin LH, Miettinen M. A great majority of GISTs with PDGFRA mutations represent gastric tumors of low or no malignant potential. Lab Invest. 2004;84(7):874-883.
-
(2004)
Lab Invest.
, vol.84
, Issue.7
, pp. 874-883
-
-
Lasota, J.1
Dansonka-Mieszkowska, A.2
Sobin, L.H.3
Miettinen, M.4
-
15
-
-
2142747025
-
KIT-negative gastrointestinal stromal tumors: Proof of concept and therapeutic implications
-
Medeiros F, Corless CL, Duensing A, et al. KIT-negative gastrointestinal stromal tumors: proof of concept and therapeutic implications. Am J Surg Pathol. 2004;28(7):889-894.
-
(2004)
Am J Surg Pathol.
, vol.28
, Issue.7
, pp. 889-894
-
-
Medeiros, F.1
Corless, C.L.2
Duensing, A.3
-
16
-
-
1842426806
-
Gastrointestinal stromal tumours (GISTs) negative for KIT (CD117 antigen) immunoreactivity
-
Debiec-Rychter M, Wasag B, Stul M, et al. Gastrointestinal stromal tumours (GISTs) negative for KIT (CD117 antigen) immunoreactivity. J Pathol. 2004;202(4):430-438.
-
(2004)
J Pathol.
, vol.202
, Issue.4
, pp. 430-438
-
-
Debiec-Rychter, M.1
Wasag, B.2
Stul, M.3
-
17
-
-
3042594995
-
The novel marker, DOG1, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of KIT or PDGFRA mutation status
-
West RB, Corless CL, Chen X, et al. The novel marker, DOG1, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of KIT or PDGFRA mutation status. Am J Pathol. 2004;165(1):107-113.
-
(2004)
Am J Pathol.
, vol.165
, Issue.1
, pp. 107-113
-
-
West, R.B.1
Corless, C.L.2
Chen, X.3
-
18
-
-
62849083680
-
Monoclonal antibody DOG1.1 shows higher sensitivity than KIT in the diagnosis of gastrointestinal stromal tumors, including unusual subtypes
-
Liegl B, Hornick JL, Corless CL, Fletcher CD. Monoclonal antibody DOG1.1 shows higher sensitivity than KIT in the diagnosis of gastrointestinal stromal tumors, including unusual subtypes. Am J Surg Pathol. 2009;33(3): 437-446.
-
(2009)
Am J Surg Pathol.
, vol.33
, Issue.3
, pp. 437-446
-
-
Liegl, B.1
Hornick, J.L.2
Corless, C.L.3
Fletcher, C.D.4
-
19
-
-
52149094786
-
Protein kinase Ctheta regulates KIT expression and proliferation in gastrointestinal stromal tumors
-
Ou WB, Zhu MJ, Demetri GD, Fletcher CD, Fletcher JA. Protein kinase Ctheta regulates KIT expression and proliferation in gastrointestinal stromal tumors. Oncogene. 2008;27(42):5624-5634.
-
(2008)
Oncogene.
, vol.27
, Issue.42
, pp. 5624-5634
-
-
Ou, W.B.1
Zhu, M.J.2
Demetri, G.D.3
Fletcher, C.D.4
Fletcher, J.A.5
-
20
-
-
0035890740
-
KIT activation is a ubiquitous feature of gastrointestinal stromal tumors
-
Rubin BP, Singer S, Tsao C, et al. KIT activation is a ubiquitous feature of gastrointestinal stromal tumors. Cancer Res. 2001;61(22):8118-8121.
-
(2001)
Cancer Res.
, vol.61
, Issue.22
, pp. 8118-8121
-
-
Rubin, B.P.1
Singer, S.2
Tsao, C.3
-
22
-
-
41149170835
-
Clinicopathologic profile of gastrointestinal stromal tumors (GISTs) with primary KIT exon 13 or exon 17 mutations: A multicenter study on 54 cases
-
Lasota J, Corless CL, Heinrich MC, et al. Clinicopathologic profile of gastrointestinal stromal tumors (GISTs) with primary KIT exon 13 or exon 17 mutations: a multicenter study on 54 cases. Mod Pathol. 2008;21(4):476-484.
-
(2008)
Mod Pathol.
, vol.21
, Issue.4
, pp. 476-484
-
-
Lasota, J.1
Corless, C.L.2
Heinrich, M.C.3
-
23
-
-
0242670019
-
PDGFRA activating mutations in gastrointestinal stromal tumors
-
Heinrich MC, Corless CL, Duensing A, et al. PDGFRA activating mutations in gastrointestinal stromal tumors. Science. 2003;299(5607):708-710.
-
(2003)
Science.
, vol.299
, Issue.5607
, pp. 708-710
-
-
Heinrich, M.C.1
Corless, C.L.2
Duensing, A.3
-
24
-
-
50249152932
-
Novel V600E BRAF mutations in imatinib-naive and imatinib-resistant gastrointestinal stromal tumors
-
Agaram NP, Wong GC, Guo T, et al. Novel V600E BRAF mutations in imatinib-naive and imatinib-resistant gastrointestinal stromal tumors. Genes Chromosomes Cancer. 2008;47(10):853-859.
-
(2008)
Genes Chromosomes Cancer.
, vol.47
, Issue.10
, pp. 853-859
-
-
Agaram, N.P.1
Wong, G.C.2
Guo, T.3
-
25
-
-
77956030786
-
Inhibition of mutated, activated BRAF in metastatic melanoma
-
Flaherty KT, Puzanov I, Kim KB, et al. Inhibition of mutated, activated BRAF in metastatic melanoma. N Engl J Med. 2010;363(9):809-819.
-
(2010)
N Engl J Med.
, vol.363
, Issue.9
, pp. 809-819
-
-
Flaherty, K.T.1
Puzanov, I.2
Kim, K.B.3
-
26
-
-
24144477000
-
NF1-associated gastrointestinal stromal tumors have unique clinical, phenotypic, and genotypic characteristics
-
Andersson J, Sihto H, Meis-Kindblom JM, Joensuu H, Nupponen N, Kindblom LG. NF1-associated gastrointestinal stromal tumors have unique clinical, phenotypic, and genotypic characteristics. Am J Surg Pathol. 2005; 29(9):1170-1176.
-
(2005)
Am J Surg Pathol.
, vol.29
, Issue.9
, pp. 1170-1176
-
-
Andersson, J.1
Sihto, H.2
Meis-Kindblom, J.M.3
Joensuu, H.4
Nupponen, N.5
Kindblom, L.G.6
-
27
-
-
33644752349
-
Gastrointestinal stromal tumors in patients with neurofibromatosis 1: A clinicopathologic and molecular genetic study of 45 cases
-
Miettinen M, Fetsch JF, Sobin LH, Lasota J. Gastrointestinal stromal tumors in patients with neurofibromatosis 1: a clinicopathologic and molecular genetic study of 45 cases. Am J Surg Pathol. 2006;30(1):90-96.
-
(2006)
Am J Surg Pathol.
, vol.30
, Issue.1
, pp. 90-96
-
-
Miettinen, M.1
Fetsch, J.F.2
Sobin, L.H.3
Lasota, J.4
-
28
-
-
51649112019
-
Therapeutic consequences from molecular biology for gastrointestinal stromal tumor patients affected by neurofibromatosis type 1
-
Mussi C, Schildhaus HU, Gronchi A, Wardelmann E, Hohenberger P. Therapeutic consequences from molecular biology for gastrointestinal stromal tumor patients affected by neurofibromatosis type 1. Clin Cancer Res. 2008; 14(14):4550-4555.
-
(2008)
Clin Cancer Res.
, vol.14
, Issue.14
, pp. 4550-4555
-
-
Mussi, C.1
Schildhaus, H.U.2
Gronchi, A.3
Wardelmann, E.4
Hohenberger, P.5
-
29
-
-
73949152219
-
Gastric stromal tumors in Carney triad are different clinically, pathologically, and behaviorally from sporadic gastric gastrointestinal stromal tumors: Findings in 104 cases
-
Zhang L, Smyrk TC, Young WF Jr, Stratakis CA, Carney JA. Gastric stromal tumors in Carney triad are different clinically, pathologically, and behaviorally from sporadic gastric gastrointestinal stromal tumors: findings in 104 cases. Am J Surg Pathol. 2010;34(1):53-64.
-
(2010)
Am J Surg Pathol.
, vol.34
, Issue.1
, pp. 53-64
-
-
Zhang, L.1
Smyrk, T.C.2
Young Jr., W.F.3
Stratakis, C.A.4
Carney, J.A.5
-
30
-
-
37349074531
-
Clinical and molecular genetics of patients with the Carney-Stratakis syndrome and germline mutations of the genes coding for the succinate dehydrogenase subunits SDHB, SDHC, and SDHD
-
Pasini B, McWhinney SR, Bei T, et al. Clinical and molecular genetics of patients with the Carney-Stratakis syndrome and germline mutations of the genes coding for the succinate dehydrogenase subunits SDHB, SDHC, and SDHD. Eur J Hum Genet. 2008;16(1):79-88.
-
(2008)
Eur J Hum Genet.
, vol.16
, Issue.1
, pp. 79-88
-
-
Pasini, B.1
McWhinney, S.R.2
Bei, T.3
-
31
-
-
78650866382
-
SDHB immunohistochemistry: A useful tool in the diagnosis of Carney-Stratakis and Carney triad gastrointestinal stromal tumors
-
Gaal J, Stratakis CA, Carney JA, et al. SDHB immunohistochemistry: a useful tool in the diagnosis of Carney-Stratakis and Carney triad gastrointestinal stromal tumors. Mod Pathol. 2011;24(1):147-151.
-
(2011)
Mod Pathol.
, vol.24
, Issue.1
, pp. 147-151
-
-
Gaal, J.1
Stratakis, C.A.2
Carney, J.A.3
-
32
-
-
77951809464
-
Immunohistochemistry for SDHB divides gastrointestinal stromal tumors (GISTs) into 2 distinct types
-
Gill AJ, Chou A, Vilain R, et al. Immunohistochemistry for SDHB divides gastrointestinal stromal tumors (GISTs) into 2 distinct types. Am J Surg Pathol. 2010;34(5):636-644.
-
(2010)
Am J Surg Pathol.
, vol.34
, Issue.5
, pp. 636-644
-
-
Gill, A.J.1
Chou, A.2
Vilain, R.3
-
33
-
-
20944442418
-
Gastrointestinal stromal tumors in children and young adults: A clinicopathologic, molecular, and genomic study of 15 cases and review of the literature
-
Prakash S, Sarran L, Socci N, et al. Gastrointestinal stromal tumors in children and young adults: a clinicopathologic, molecular, and genomic study of 15 cases and review of the literature. J Pediatr Hematol Oncol. 2005;27(4): 179-187.
-
(2005)
J Pediatr Hematol Oncol.
, vol.27
, Issue.4
, pp. 179-187
-
-
Prakash, S.1
Sarran, L.2
Socci, N.3
-
34
-
-
49649119001
-
Molecular characterization of pediatric gastrointestinal stromal tumors
-
Agaram NP, Laquaglia MP, Ustun B, et al. Molecular characterization of pediatric gastrointestinal stromal tumors. Clin Cancer Res. 2008;14(10):3204- 3215.
-
(2008)
Clin Cancer Res.
, vol.14
, Issue.10
, pp. 3204-3215
-
-
Agaram, N.P.1
Laquaglia, M.P.2
Ustun, B.3
-
36
-
-
78651082042
-
Defects in succinate dehydrogenase in gastrointestinal stromal tumors lacking KIT and PDGFRA mutations
-
Janeway KA, Kim SY, Lodish M, et al. Defects in succinate dehydrogenase in gastrointestinal stromal tumors lacking KIT and PDGFRA mutations. Proc Natl Acad Sci USA. 2011;108(1):314-318.
-
(2011)
Proc Natl Acad Sci USA.
, vol.108
, Issue.1
, pp. 314-318
-
-
Janeway, K.A.1
Kim, S.Y.2
Lodish, M.3
-
37
-
-
79953183996
-
Pediatrictype" gastrointestinal stromal tumors in adults: Distinctive histology predicts genotype and clinical behavior
-
Rege TA, Wagner AJ, Corless CL, Heinrich MC, Hornick JL. "Pediatrictype" gastrointestinal stromal tumors in adults: distinctive histology predicts genotype and clinical behavior. Am J Surg Pathol. 2011;35(4):495-504.
-
(2011)
Am J Surg Pathol.
, vol.35
, Issue.4
, pp. 495-504
-
-
Rege, T.A.1
Wagner, A.J.2
Corless, C.L.3
Heinrich, M.C.4
Hornick, J.L.5
-
38
-
-
67650472798
-
Sunitinib treatment in pediatric patients with advanced GIST following failure of imatinib
-
Janeway KA, Albritton KH, Van Den Abbeele AD, et al. Sunitinib treatment in pediatric patients with advanced GIST following failure of imatinib. Pediatr Blood Cancer. 2009;52(7):767-771.
-
(2009)
Pediatr Blood Cancer.
, vol.52
, Issue.7
, pp. 767-771
-
-
Janeway, K.A.1
Albritton, K.H.2
Van Den Abbeele, A.D.3
-
39
-
-
0031848146
-
Familial gastrointestinal stromal tumours with germline mutation of the KIT gene
-
Nishida T, Hirota S, Taniguchi M, et al. Familial gastrointestinal stromal tumours with germline mutation of the KIT gene. Nat Genet. 1998;19(4):323-324.
-
(1998)
Nat Genet.
, vol.19
, Issue.4
, pp. 323-324
-
-
Nishida, T.1
Hirota, S.2
Taniguchi, M.3
-
40
-
-
0347361543
-
PDGFRA germline mutation in a family with multiple cases of gastrointestinal stromal tumor
-
Chompret A, Kannengiesser C, Barrois M, et al. PDGFRA germline mutation in a family with multiple cases of gastrointestinal stromal tumor. Gastroenterology. 2004;126(1):318-321.
-
(2004)
Gastroenterology.
, vol.126
, Issue.1
, pp. 318-321
-
-
Chompret, A.1
Kannengiesser, C.2
Barrois, M.3
-
41
-
-
37349043267
-
Clinical, histopathologic, molecular and therapeutic findings in a large kindred with gastrointestinal stromal tumor
-
Kleinbaum EP, Lazar AJ, Tamborini E, et al. Clinical, histopathologic, molecular and therapeutic findings in a large kindred with gastrointestinal stromal tumor. Int J Cancer. 2008;122(3):711-718.
-
(2008)
Int J Cancer.
, vol.122
, Issue.3
, pp. 711-718
-
-
Kleinbaum, E.P.1
Lazar, A.J.2
Tamborini, E.3
-
42
-
-
12144286747
-
Pleomorphic characteristics of a germ-line KIT mutation in a large kindred with gastrointestinal stromal tumors, hyperpigmentation, and dysphagia
-
Robson ME, Glogowski E, Sommer G, et al. Pleomorphic characteristics of a germ-line KIT mutation in a large kindred with gastrointestinal stromal tumors, hyperpigmentation, and dysphagia. Clin Cancer Res. 2004;10(4):1250-1254.
-
(2004)
Clin Cancer Res.
, vol.10
, Issue.4
, pp. 1250-1254
-
-
Robson, M.E.1
Glogowski, E.2
Sommer, G.3
-
43
-
-
0033984319
-
Two hundred gastrointestinal stromal tumors: Recurrence patterns and prognostic factors for survival
-
DeMatteo RP, Lewis JJ, Leung D, Mudan SS, Woodruff JM, Brennan MF. Two hundred gastrointestinal stromal tumors: recurrence patterns and prognostic factors for survival. Ann Surg. 2000;231(1):51-58.
-
(2000)
Ann Surg.
, vol.231
, Issue.1
, pp. 51-58
-
-
Dematteo, R.P.1
Lewis, J.J.2
Leung, D.3
Mudan, S.S.4
Woodruff, J.M.5
Brennan, M.F.6
-
44
-
-
0036301722
-
Diagnosis of gastrointestinal stromal tumors: A consensus approach
-
Fletcher CD, Berman JJ, Corless C, et al. Diagnosis of gastrointestinal stromal tumors: a consensus approach. Hum Pathol. 2002;33(5):459-465.
-
(2002)
Hum Pathol.
, vol.33
, Issue.5
, pp. 459-465
-
-
Fletcher, C.D.1
Berman, J.J.2
Corless, C.3
-
45
-
-
33750618188
-
Gastrointestinal stromal tumors: Pathology and prognosis at different sites
-
Miettinen M, Lasota J. Gastrointestinal stromal tumors: pathology and prognosis at different sites. Semin Diagn Pathol. 2006;23(2):70-83.
-
(2006)
Semin Diagn Pathol.
, vol.23
, Issue.2
, pp. 70-83
-
-
Miettinen, M.1
Lasota, J.2
-
46
-
-
33646381326
-
Gastrointestinal stromal tumors with KIT exon 11 deletions are associated with poor prognosis
-
Andersson J, Bümming P, Meis-Kindblom JM, et al. Gastrointestinal stromal tumors with KIT exon 11 deletions are associated with poor prognosis. Gastroenterology. 2006;130(6):1573-1581.
-
(2006)
Gastroenterology.
, vol.130
, Issue.6
, pp. 1573-1581
-
-
Andersson, J.1
Bümming, P.2
Meis-Kindblom, J.M.3
-
47
-
-
77949898532
-
Gastrointestinal Stromal Tumor Meta-Analysis Group (MetaGIST). Comparison of two doses of imatinib for the treatment of unresectable or metastatic gastrointestinal stromal tumors: A meta-analysis of 1, 640 patients
-
Gastrointestinal Stromal Tumor Meta-Analysis Group (MetaGIST). Comparison of two doses of imatinib for the treatment of unresectable or metastatic gastrointestinal stromal tumors: a meta-analysis of 1, 640 patients. J Clin Oncol. 2010;28(7):1247-1253.
-
(2010)
J Clin Oncol.
, vol.28
, Issue.7
, pp. 1247-1253
-
-
-
48
-
-
56749156604
-
Correlation of kinase genotype and clinical outcome in the North American Intergroup Phase III Trial of imatinib mesylate for treatment of advanced gastrointestinal stromal tumor: CALGB 150105 Study by Cancer and Leukemia Group B and Southwest Oncology Group
-
Heinrich MC, Owzar K, Corless CL, et al. Correlation of kinase genotype and clinical outcome in the North American Intergroup Phase III Trial of imatinib mesylate for treatment of advanced gastrointestinal stromal tumor: CALGB 150105 Study by Cancer and Leukemia Group B and Southwest Oncology Group. J Clin Oncol. 2008;26(33):5360-5367.
-
(2008)
J Clin Oncol.
, vol.26
, Issue.33
, pp. 5360-5367
-
-
Heinrich, M.C.1
Owzar, K.2
Corless, C.L.3
-
49
-
-
33746401591
-
KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours
-
Debiec-Rychter M, Sciot R, Le Cesne A, et al. KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours. Eur J Cancer. 2006;42(8):1093-1103.
-
(2006)
Eur J Cancer.
, vol.42
, Issue.8
, pp. 1093-1103
-
-
Debiec-Rychter, M.1
Sciot, R.2
Le Cesne, A.3
-
50
-
-
0642368571
-
Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor
-
Heinrich MC, Corless CL, Demetri GD, et al. Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor. J Clin Oncol. 2003;21(23):4342-4349.
-
(2003)
J Clin Oncol.
, vol.21
, Issue.23
, pp. 4342-4349
-
-
Heinrich, M.C.1
Corless, C.L.2
Demetri, G.D.3
-
51
-
-
77951875556
-
NCCN Task Force report: Update on the management of patients with gastrointestinal stromal tumors
-
Demetri GD, von Mehren M, Antonescu CR, et al. NCCN Task Force report: update on the management of patients with gastrointestinal stromal tumors. J Natl Compr Canc Netw. 2010;8 (suppl 2):S1-S41.
-
(2010)
J Natl Compr Canc Netw.
, vol.8
, Issue.SUPPL. 2
-
-
Demetri, G.D.1
Von Mehren, M.2
Antonescu, C.R.3
-
52
-
-
66549113366
-
ESMO Guidelines Working Group. Gastrointestinal stromal tumours: ESMO clinical recommendations for diagnosis, treatment and follow-up
-
Casali PG, Jost L, Reichardt P, Schlemmer M, Blay JY; ESMO Guidelines Working Group. Gastrointestinal stromal tumours: ESMO clinical recommendations for diagnosis, treatment and follow-up. Ann Oncol. 2009;20(suppl 4): 64-67.
-
(2009)
Ann Oncol.
, vol.20
, Issue.SUPPL. 4
, pp. 64-67
-
-
Casali, P.G.1
Jost, L.2
Reichardt, P.3
Schlemmer, M.4
Blay, J.Y.5
-
53
-
-
67650306170
-
Imatinib plasma levels are correlated with clinical benefit in patients with unresectable/metastatic gastrointestinal stromal tumors
-
Demetri GD, Wang Y, Wehrle E, et al. Imatinib plasma levels are correlated with clinical benefit in patients with unresectable/metastatic gastrointestinal stromal tumors. J Clin Oncol. 2009;27(19):3141-3147.
-
(2009)
J Clin Oncol.
, vol.27
, Issue.19
, pp. 3141-3147
-
-
Demetri, G.D.1
Wang, Y.2
Wehrle, E.3
-
54
-
-
77951922479
-
Cross-sectional study of imatinib plasma trough levels in patients with advanced gastrointestinal stromal tumors: Impact of gastrointestinal resection on exposure to imatinib
-
Yoo C, Ryu MH, Kang BW, et al. Cross-sectional study of imatinib plasma trough levels in patients with advanced gastrointestinal stromal tumors: impact of gastrointestinal resection on exposure to imatinib. J Clin Oncol. 2010;28(9): 1554-1559.
-
(2010)
J Clin Oncol.
, vol.28
, Issue.9
, pp. 1554-1559
-
-
Yoo, C.1
Ryu, M.H.2
Kang, B.W.3
-
55
-
-
24944529613
-
Initial and late resistance to imatinib in advanced gastrointestinal stromal tumors are predicted by different prognostic factors: A European Organisation for Research and Treatment of Cancer-Italian Sarcoma Group-Australasian Gastrointestinal Trials Group study
-
Van Glabbeke M, Verweij J, Casali PG, et al. Initial and late resistance to imatinib in advanced gastrointestinal stromal tumors are predicted by different prognostic factors: a European Organisation for Research and Treatment of Cancer-Italian Sarcoma Group-Australasian Gastrointestinal Trials Group study. J Clin Oncol. 2005;23(24):5795-5804.
-
(2005)
J Clin Oncol.
, vol.23
, Issue.24
, pp. 5795-5804
-
-
Van Glabbeke, M.1
Verweij, J.2
Casali, P.G.3
-
56
-
-
50249092801
-
Heterogeneity of kinase inhibitor resistance mechanisms in GIST
-
Liegl B, Kepten I, Le C, et al. Heterogeneity of kinase inhibitor resistance mechanisms in GIST. J Pathol. 2008;216(1):64-74.
-
(2008)
J Pathol.
, vol.216
, Issue.1
, pp. 64-74
-
-
Liegl, B.1
Kepten Le, I.C.2
-
57
-
-
33749505836
-
Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: A randomised controlled trial
-
Demetri GD, van Oosterom AT, Garrett CR, et al. Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial. Lancet. 2006;368(9544):1329- 1338.
-
(2006)
Lancet.
, vol.368
, Issue.9544
, pp. 1329-1338
-
-
Demetri, G.D.1
Van Oosterom, A.T.2
Garrett, C.R.3
-
58
-
-
33947504730
-
Sunitinib: From rational design to clinical efficacy
-
Chow LQ, Eckhardt SG. Sunitinib: from rational design to clinical efficacy. J Clin Oncol. 2007;25(7):884-896.
-
(2007)
J Clin Oncol.
, vol.25
, Issue.7
, pp. 884-896
-
-
Chow, L.Q.1
Eckhardt, S.G.2
-
59
-
-
23844531811
-
Results from a continuation trial of SU11248 in patients (pts) with imatinib (IM)-resistant gastrointestinal stromal tumor (GIST) [2005 ASCO Annual Meeting Proceedings]
-
Maki RG, Fletcher JA, Heinrich MC, et al. Results from a continuation trial of SU11248 in patients (pts) with imatinib (IM)-resistant gastrointestinal stromal tumor (GIST) [2005 ASCO Annual Meeting Proceedings]. J Clin Oncol. 2005; 23(16S, part I of II) (suppl): 9011.
-
(2005)
J Clin Oncol.
, vol.23
, Issue.16
, pp. 9011
-
-
Maki, R.G.1
Fletcher, J.A.2
Heinrich, M.C.3
-
60
-
-
56749098278
-
Primary and secondary kinase genotypes correlate with the biological and clinical activity of sunitinib in imatinib-resistant gastrointestinal stromal tumor
-
Heinrich MC, Maki RG, Corless CL, et al. Primary and secondary kinase genotypes correlate with the biological and clinical activity of sunitinib in imatinib-resistant gastrointestinal stromal tumor. J Clin Oncol. 2008;26(33): 5352-5359.
-
(2008)
J Clin Oncol.
, vol.26
, Issue.33
, pp. 5352-5359
-
-
Heinrich, M.C.1
Maki, R.G.2
Corless, C.L.3
-
61
-
-
33749461709
-
Heat shock protein 90 inhibition in imatinib-resistant gastrointestinal stromal tumor
-
Bauer S, Yu LK, Demetri GD, Fletcher JA. Heat shock protein 90 inhibition in imatinib-resistant gastrointestinal stromal tumor. Cancer Res. 2006;66(18): 9153-9161.
-
(2006)
Cancer Res.
, vol.66
, Issue.18
, pp. 9153-9161
-
-
Bauer, S.1
Yu, L.K.2
Demetri, G.D.3
Fletcher, J.A.4
-
62
-
-
51449118446
-
Inhibition of heat shock protein 90 (Hsp90) with the novel agent IPI-504 in metastatic GIST following failure of tyrosine kinase inhibitors (TKIs) or other sarcomas: Clinical results from phase i trial
-
Abstract 10503
-
Wagner AJ, Morgan JA, Chugh R, et al. Inhibition of heat shock protein 90 (Hsp90) with the novel agent IPI-504 in metastatic GIST following failure of tyrosine kinase inhibitors (TKIs) or other sarcomas: clinical results from phase I trial. J Clin Oncol. 2008;26 (suppl). Abstract 10503.
-
(2008)
J Clin Oncol.
, vol.26
, Issue.SUPPL.
-
-
Wagner, A.J.1
Morgan, J.A.2
Chugh, R.3
-
63
-
-
36749030022
-
KIT oncogenic signaling mechanisms in imatinib-resistant gastrointestinal stromal tumor: PI3-kinase/AKT is a crucial survival pathway
-
Bauer S, Duensing A, Demetri GD, Fletcher JA. KIT oncogenic signaling mechanisms in imatinib-resistant gastrointestinal stromal tumor: PI3-kinase/AKT is a crucial survival pathway. Oncogene. 2007;26(54):7560-7568.
-
(2007)
Oncogene.
, vol.26
, Issue.54
, pp. 7560-7568
-
-
Bauer, S.1
Duensing, A.2
Demetri, G.D.3
Fletcher, J.A.4
-
64
-
-
77957171405
-
A phase I-II study of everolimus (RAD001) in combination with imatinib in patients with imatinib-resistant gastrointestinal stromal tumors
-
Schöffski P, Reichardt P, Blay JY, et al. A phase I-II study of everolimus (RAD001) in combination with imatinib in patients with imatinib-resistant gastrointestinal stromal tumors. Ann Oncol. 2010;21(10):1990-1998.
-
(2010)
Ann Oncol.
, vol.21
, Issue.10
, pp. 1990-1998
-
-
Schöffski, P.1
Reichardt, P.2
Blay, J.Y.3
|