Engineering a hyper-catalytic enzyme by photoactivated conformation modulation

Journal of Physical Chemistry Letters

Volumn 3, Issue 9, 2012, Pages 1142-1146

  Agarwal, Pratul K ^a   Schultz, Christopher ^b   Kalivretenos, Aristotle ^c   Ghosh, Brahma ^d   Broedel, Sheldon E ^b  

^a OAK RIDGE NATIONAL LABORATORY   (United States)

^b AthenaES   (United States)

^c Aurora Analytics   (United States)

^d PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; AZOBENZENE MOIETY; CANDIDA ANTARCTICA LIPASE B; CATALYTIC MECHANISMS; COMPUTATIONAL MODEL; COMPUTATIONAL MODELING; CONFORMATIONAL FLUCTUATIONS; DYNAMICAL COUPLING; ENZYME CONFORMATIONS; ENZYME ENGINEERING; MECHANICAL ENERGIES; PHOTO-ACTIVATED; PHOTOACTIVATION; SURFACE LOOPS; TRANS CONFORMATIONS; TWO SOURCES;

CATALYSIS; CHEMICAL MODIFICATION; ENZYME ACTIVITY; LIGHT SOURCES; MODULATION; QUANTUM CHEMISTRY;

CONFORMATIONS;

EID: 84860543983     PISSN: None     EISSN: 19487185     Source Type: Journal    
DOI: 10.1021/jz201675m     Document Type: Article

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