Changes in peripheral T-lymphocyte subsets in acute-on-chronic liver failure patients with artificial liver support system

Hepato-Gastroenterology

Volumn 59, Issue 115, 2012, Pages 814-817

  Lou, Yu Feng ^a   Dong, Wei ^b   Ye, Bo ^a   Lin, Sha ^a   Mao, Wei Lin ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Department of Clinical Laboratory   (China)

Author keywords

Acute on chronic liver failure; Artificial liver support system; CD4 CD8 ratio; T lymphocyte subsets

Indexed keywords

ACUTE ON CHRONIC LIVER FAILURE; ADULT; ARTICLE; ARTIFICIAL LIVER; CD4 CD8 RATIO; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; HOSPITALIZATION; HUMAN; IMMUNOLOGICAL PARAMETERS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; SURVIVAL; THERAPY EFFECT; TREATMENT OUTCOME;

ADULT; CASE-CONTROL STUDIES; CD4 LYMPHOCYTE COUNT; CD4-CD8 RATIO; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CHI-SQUARE DISTRIBUTION; CHINA; END STAGE LIVER DISEASE; FEMALE; FLOW CYTOMETRY; HEPATITIS B; HUMANS; LIVER FAILURE, ACUTE; LIVER, ARTIFICIAL; MALE; MIDDLE AGED; TIME FACTORS; TREATMENT OUTCOME;

EID: 84860539085     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: 10.5754/hge10064     Document Type: Article

References (20)

1. Thimme R, Wieland S, Steiger C, et al.: CD8 +T cells mediate viral clearance and disease pathogenesis during acute hepatitis B virus infection. J Virol 2003; 77:68-76. (Pubitemid 36004947)
2. Bertoletti A, Maini M, Williams R: Role of hepatitis B virus specific cytotoxic T cells in liver damage and viral control. Antivir Res 2003; 60:61-66. (Pubitemid 37452447)
3. + T cells associated with the control of infection. Gastroenterology 1999; 117:1386-1396.
4. Eyigün CP, Avci IY, Sengül A, Hacibektasoglu A, Van Thiel DH: Immune status of individuals with differing clinical courses of HBV infection. Hepato-gastroenterol 1999; 46:1890-1894. (Pubitemid 29366366)
5. Sing G, Butterworth L, Chen X, Bryant A, Cooksley G: Composition of peripheral blood lymphocyte populations during different stages of chronic infection with hepatitis B virus. J Viral Hepat 1998; 5:83-93. (Pubitemid 28383572)
6. Maini MK, Bertoletti A: How can the cellular immune response control hepatitis B virus replication? J Viral Hepat 2000; 7:321-326.
7. Fei GZ, Sylvan SP, Yao GB, Hellström UB: Quantitative monitoring of serum hepatitis B virus DNA and blood lymphocyte subsets during combined prednisolone and interferon-alpha therapy in patients with chronic hepatitis B. J Viral Hepat 1999; 6:219-227. (Pubitemid 29260105)
8. Im EH, Lee BS, Sung JK, et al.: T cell subsets in chronic hepatitis B and the effect of prednisolone withdrawal and interferon alpha 2b. Korean J Intern Med 1999; 14:1-8.
9. Scully LJ, Brown D, Lloyd C, Shein R, Thomas HC: Immunological studies before and during interferon therapy in chronic HBV infection: identification of factors predicting response. Hepatology 1990; 5:1111-1117.
10. Tsuji H, Murai K, Akagi K, Fujishima M: Effects of recombinant leukocyte interferon on serum immunoglobulin concentrations and lymphocyte subpopulations in chronic hepatitis B. J Clin Immunol 1990; 10:38-44. (Pubitemid 20085857)
11. Kjaergard LL, Liu J, Als-Nielsen B, Gluud C: Artificial and bio-artificial support systems for acute and acute-on-chronic live failure. A systemic review. JAMA 2003; 289:217-222. (Pubitemid 36068710)
12. Mitzner SR, Stange J, Klammt S, et al.: Improvement of hepatorenal syndrome with extracorporeal albumin dialysis MARS: results of a prospective, randomized, controlled, clinical trial. Liver Transplant 2000; 6:277-286. (Pubitemid 30317221)
13. Chiu A, Chan LMY, Fan ST: Molecular adsorbent re-circulating system treatment for patients with liver failure: the Hong Kong experience. Liver Int 2004; 26:695-702.
14. Everhart JE, Lombardero M, Detre KM, Zetterman RK, Wiesner RH, Lake JR: Increased waiting time for liver transplantation results in higher mortality. Transplantation 1997; 64:1300-1306. (Pubitemid 27495964)
15. Chen S, Zhang L, Shi Y, Yang X, Wang M: Molecular adsorbent re-circulating system: clinical experience in patients with liver failure based on hepatitis B in China. Liver 2002; 22:48-51.
16. Iwai H, Nagaki M, Naito T, et al.: Removal of endotoxin and cytokines by plasma exchange in patients with acute hepatic failure. Crit Care Med 1998; 26:873-876. (Pubitemid 28211398)
17. Catalina MV, Barrio J, Anaya F, et al.: Hepatic and systemic hemodynamic changes after MARS in patients with acute on chronic liver failure. Liver Int 2003; 23:39-43. (Pubitemid 37264917)
18. Stange J, Mitzner SR, Klammt S, et al.: Liver support by extra-corporeal blood purification: a clinical observation. Liver Transplant 2000; 6:603-613.
19. Genel F, Unal F, Ozgenc F, Aksu G, Aydogdu S, Kutukculer N, Yagci RV: Decreased ratio of CD4/CD8 lymphocytes might be predictive for successful interferon alpha and lamivudine combined therapy in childhood chronic hepatitis B infection: A preliminary study. J Gastroenterol Hepatol 2003; 18:645-650. (Pubitemid 36791701)
20. Scully LJ, Brown D, Lloyd C, Shein R, Thomas HC: Immunological studies before and during Interferon therapy in Chronic HBV Infection: Identification of factors predicting response. Hepatology 1990; 12:1111-1117.