Composition of peripheral blood lymphocyte populations during different stages of chronic infection with hepatitis B virus

Journal of Viral Hepatitis

Volumn 5, Issue 2, 1998, Pages 83-93

  Sing, G ^a   Butterworth, L ^a   Chen, X ^a   Bryant, A ^a   Cooksley, G ^a  

^a Royal Brisbane and Womens Hospital Research Foundation   (Australia)

Author keywords

Chronic infection; Flow cytometry; Hepatitis B virus; T cell subsets

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD57 ANTIGEN; CD8 ANTIGEN; HLA DR ANTIGEN; T LYMPHOCYTE RECEPTOR;

ADULT; ARTICLE; CHRONIC HEPATITIS; CLINICAL ARTICLE; FEMALE; FLOW CYTOMETRY; HELPER CELL; HEPATITIS B; HUMAN; IMMUNOPHENOTYPING; LYMPHOCYTE COUNT; MALE; PRIORITY JOURNAL; SEROCONVERSION; T LYMPHOCYTE SUBPOPULATION;

ADOLESCENT; ADULT; AGED; BIOLOGICAL MARKERS; CELL SEPARATION; FEMALE; FLOW CYTOMETRY; HEPATITIS B, CHRONIC; HUMANS; MALE; MIDDLE AGED; PHENOTYPE; T-LYMPHOCYTE SUBSETS;

EID: 0031876242     PISSN: 13520504     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2893.1998.00088.x     Document Type: Article

References (31)

1. Gerlich WH, Lu X. Interaction of hepatitis B virus with hepatocytes. In: Mahy BJ, Compans RW, eds. Immunobiology and Pathogenesis of Persistent Virus Infections. Amsterdam: OPA, 1996: 195-208.
2. Bertoletti A, Ferrari C, Fiaccadori F et al. HLA class I-restricted human cytotoxic T cells recognize endogenously synthesized hepatitis B virus nucleocapsid antigen. Proc Natl Acad Sci USA 1991; 88: 10445-10449.
3. Nayersina R, Fowler P, Guilhot S et al. HLA A2 restricted cytotoxic T lymphocyte responses to multiple hepatitis B surface antigen epitopes during hepatitis B virus infection. J Immunol 1993; 150: 4659-4671.
4. Rehermann B, Person J, Redeker A et al. The cytotoxic T lymphocyte response to multiple hepatitis B virus polymerase epitopes during and after acute viral hepatitis. J Exp Med 1995; 181: 1047-1058.
5. Tsai SL, Chen PJ, Lai MY et al. Acute exacerbations of chronic hepatitis are accompanied by increased T cell responses to hepatitis B core and e antigens. J Clin Invest 1992; 89: 87-96.
6. Marinos G, Torre F, Choksi S et al. Induction of T-helper cell response to hepatitis B core antigen in chronic hepatitis B: a major factor in activation of the host immune response to hepatitis B virus. Hepatology 1995; 22: 1040-1049.
7. Rehermann B, Lau D, Hoofnagle JH, Chisari FV. Cytotoxic T lymphocyte responsiveness after resolution of chronic hepatitis B virus infection. J Clin Invest 1996; 97: 1655-1665.
8. Van Hecke E, Paradijs J, Molitor C et al. Hepatitis B virus-specific cytotoxic T lymphocyte responses in patients with acute and chronic hepatitis B virus infection. J Hepatol 1994; 20: 514-523.
9. Chu C-M, Lliaw Y-F. Peripheral T-cell subsets in asymptomatic hepatitis B-virus carriers. Cell Immunol 1986; 98: 533-537.
10. Dienstag JL. Immunologic mechanisms in chronic viral hepatitis. In: Vyas GN, Dienstag JL, Hoofnagle JH, eds. Viral Hepatitis and Liver Disease. New York: Grune & Stratton, 1984: 135-166.
11. Thomas HC, Brown D, Routhier G et al. Inducer and suppressor T cells in hepatitis B virus induced liver disease. Hepatology 1982; 2: 202-204.
12. Carella G, Chatenoud L, Degos F, Bach MA. Regulatory T cell subset imbalance in chronic active hepatitis. J Clin Immunol 1982; 2: 93-100.
13. Alexander GLM, Mondelli M, Naumov NV et al. Functional characterization of peripheral blood lymphocytes in chronic HBsAg carriers. Clin Exp Immunol 1986; 63: 498-507.
14. Regenstein FG, Roodman ST, Perrillo RP. Immunoregulatory T cell subsets in chronic hepatitis B virus infection: the influence of homosexuality. Hepatology 1983; 3: 951-954.
15. Robayes G, De Groote J, Vandeputte M. Suppressor cell function in liver disease. Lancet 1983; 2: 342.
16. + cells in normal, healthy individuals: correlations with HCMV carrier status, phenotypic and functional analyses. Clin Exp Immunol 1993; 94: 297-305.
17. Yamamoto T, Osaki T, Yoneda K, Ueta E. Immunological investigation of adult patients with primary herpes simplex virus-1 infection. J Oral Pathol Med 1993; 22: 263-267.
18. - populations suggest regulatory responses linked to loss of CD4 lymphocytes. The Multicenter AIDS Cohort Study. J AIDS 1993; 6: 153-161.
19. Levacher M, Hulstaert F, Tallet S, Ullery S, Pocidalo JJ, Bach BA. The significance of activation markers on CD8 lymphocytes in human immunodeficiency syndrome: staging and prognostic value. Clin Exp Immunol 1992; 90: 376-382.
20. Barnaba V, Tamburrini E, Laghi V et al. Peripheral blood mononuclear cells and regulatory T cells in acute viral hepatitis. Gut 1985; 26: 739-744.
21. + cells in patients with chronic viral hepatitis. FEMS Immunol Med Microbiol 1995; 10: 115-118.
22. Kabelitz D. Function and specificity of human gamma/ delta-positive T cells. Crit Rev Immunol 1992; 11: 281-303.
23. Sturm E, Braakman E, Fisch P, Vreugdenhil RJ, Sondel P, Bolhuis RL. Human Vγ9Vδ2 T cell receptor-Vγδ lymphocytes show specificity to Daudi Burkitt lymphoma cells. J Immunol 1990; 145: 3203-3208.
24. Bukowski JF, Monta CT, Brenner MB. Recognition and destruction of virus-infected cells by human γδ CTL. J Immunol 1994; 153: 5133-5140.
25. Janeway CA Jr, Jones B, Hayday A. Specificity and function of T cells bearing γδ receptors. Immunol Today 1988; 9: 73-76.
26. Carding SR, Allan W, Kyes S, Hayday A, Bottomly K, Doherty PC. Late dominance of the inflammatory process in murine influenza by gamma/delta + T cells. J Exp Med 1990; 172: 1225-1231.
27. Hou S, Katz JM, Doherty PC, Carding SR. Extent of γδ T cell involvement in the pneumonia caused by Sendai virus. Cell Immunol 1992; 143: 183-193.
28. + memory T lymphocytes in acute hepatitis B virus infection. J Hepatol 1993; 18: 295-300.
29. + lymphocyte population in the blood of SIV-infected macaques is not reflected in lymph nodes. AIDS Res Human Retrovir 1993; 9: 639-645.
30. Pham B-N, Mosnier JF, Walker F et al. Flow cytometry CD4+/CD8+ ratio of liver-derived lymphocytes correlates with viral replication in chronic hepatitis B. Clin Exp Immunol 1994; 97: 403-410.
31. Echaniz P, Arrizbalaga J, Irabarren JA, Cuadrado E. CD8+CD38+ and CD8+DR+ peripheral blood lymphoid subsets of HIV-infected intravenous drug abusers correlate with CD4+ cell counts and proliferation to mitogens. Cell Immunol 1993; 150: 72-80.