The intracellular Ig fold: A robust protein scaffold for the engineering of molecular recognition

Protein Engineering, Design and Selection

Volumn 25, Issue 5, 2012, Pages 205-212

  Bruning, Marc ^a,b   Barsukov, Igor ^a   Franke, Barbara ^a   Barbieri, Sonia ^a,b   Volk, Martin ^a   Leopoldseder, Sonja ^b   Ucurum, Zhre ^b   Mayans, Olga ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b UNIVERSITY OF BASEL   (Switzerland)

Author keywords

differential scanning fluorimetry; infrared spectroscopy; intracellular Ig domain; NMR spectroscopy; protein scaffold engineering for peptide display

Indexed keywords

BINDING EFFICIENCY; CD LOOPS; DISPLAY SYSTEM; EXOGENOUS PEPTIDES; FLUORIMETRY; FUNCTIONALIZATIONS; INTRACELLULAR IG DOMAIN; ISOTHERMAL TITRATION CALORIMETRY; MODULAR COMPONENTS; MULTIPLE APPLICATIONS; SCAFFOLD ENGINEERING; STRUCTURAL CORE; SURFACE LOOPS;

CYTOLOGY; DISPLAY DEVICES; ESCHERICHIA COLI; FOURIER TRANSFORM INFRARED SPECTROSCOPY; GRAFTING (CHEMICAL); INFRARED SPECTROSCOPY; MOLECULAR RECOGNITION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PEPTIDES;

SCAFFOLDS (BIOLOGY);

CONNECTIN; IMMUNOGLOBULIN;

AMINO ACID SEQUENCE; ARTICLE; CHIMERA; CONTROLLED STUDY; ESCHERICHIA COLI; FLUOROMETRY; INFRARED SPECTROSCOPY; ISOTHERMAL TITRATION CALORIMETRY; MOLECULAR RECOGNITION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN ENGINEERING; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STABILITY; PROTEIN STRUCTURE;

EPITOPES; ESCHERICHIA COLI; IMMUNOGLOBULINS; MUSCLE PROTEINS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDES; PROTEIN ENGINEERING; PROTEIN FOLDING; PROTEIN KINASES; PROTEIN STRUCTURE, TERTIARY; PROTEINS; RECOMBINANT PROTEINS;

ESCHERICHIA COLI;

EID: 84860492711     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzs007     Document Type: Article

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