Diffuse in-stent restenosis of CYPHER® stent due to hypersensitivity reaction confirmed by pathohistological findings

Heart and Vessels

Volumn 27, Issue 1, 2012, Pages 110-113

  Otsuka, Yoritaka ^a   Nakamura, Masanori ^b   Kokubu, Nobuaki ^b   Tonooka, Akiko ^b   Inoue, Katsumi ^c   Higami, Tetsuya ^b  

^a FUKUOKA WAJIRO HOSPITAL   (Japan)

^b SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c KOKURA MEMORIAL HOSPITAL   (Japan)

Author keywords

Drug eluting stent; Hypersensitivity; In stent restenosis

Indexed keywords

ACETYLSALICYLIC ACID; CYPHER; RAPAMYCIN; TICLOPIDINE; UNCLASSIFIED DRUG;

ADULT; ANGINA PECTORIS; ANGIOCARDIOGRAPHY; ANTERIOR MYOCARDIAL INFARCTION; ARTERY ANASTOMOSIS; ARTERY OCCLUSION; ARTICLE; BLOOD CELL COUNT; CASE REPORT; CHRONIC INFLAMMATION; CORONARY ARTERY BYPASS GRAFT; CORONARY ARTERY CIRCUMFLEX BRANCH; DISEASE SEVERITY; DRUG ELUTING STENT; DRUG HYPERSENSITIVITY; ENDARTERECTOMY; EOSINOPHIL COUNT; HEART FAILURE; HEART INFARCTION; HISTOPATHOLOGY; HOSPITAL ADMISSION; HUMAN; HYPERLIPIDEMIA; HYPERSENSITIVITY REACTION; IN-STENT RESTENOSIS; INTERNAL MAMMARY ARTERY; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; MEDICAL HISTORY; PERCUTANEOUS CORONARY INTERVENTION; PRIORITY JOURNAL; RECURRENT DISEASE; HYPERSENSITIVITY; INFLAMMATION; INSTRUMENTATION; MIDDLE AGED; PATHOLOGY; PROSTHESIS; RADIOGRAPHY; RESTENOSIS; TRANSLUMINAL CORONARY ANGIOPLASTY; TREATMENT OUTCOME;

ANGIOPLASTY, BALLOON, CORONARY; CORONARY ANGIOGRAPHY; CORONARY OCCLUSION; CORONARY RESTENOSIS; DRUG-ELUTING STENTS; ENDARTERECTOMY; HUMANS; HYPERSENSITIVITY; INFLAMMATION; MALE; MIDDLE AGED; PROSTHESIS DESIGN; TREATMENT OUTCOME;

EID: 84860487005     PISSN: 09108327     EISSN: 16152573     Source Type: Journal    
DOI: 10.1007/s00380-011-0145-1     Document Type: Article

References (15)

1. Kirtane AJ, Gupta A, Iyengar S, Moses JW, Leon MB, Applegate R, Brodie B, Hannan E, Harjai K, Jensen LO, Park SJ, Perry R, Racz M, Saia F, Tu JV, Waksman R, Lansky AJ, Mehran R, Stone GW (2009) Safety and efficacy of drug-eluting and bare metal stents: comprehensive meta-analysis of randomized trials and observational studies. Circulation 119: 3198-3206
2. Otsuka Y, Yamanaka F, Yamane T, Adachi T, Tada E, Yagi N, Kataoka Y, Kasahara Y, Nonogi H (2011) A rare connection by newly formed conduit vessels between the left internal mammalian artery and radial artery bypass grafts after failure of grafts. Heart Vessels 26: 226-230
3. Joner M, Finn AV, Farb A, Mont EK, Kolodgie FD, Ladich E, Kutys R, Skorija K, Gold HK, Virmani R (2006) Pathology of drug-eluting stents in humans: delayed healing and late thrombotic risk. J Am Coll Cardiol 48: 193-202
4. Virmani R, Guagliumi G, Farb A, Musumeci G, Grieco N, Motta T, Mihalcsik L, Tespili M, Valsecchi O, Kolodgie FD (2004) Localized hypersensitivity and late coronary thrombosis secondary to a sirolimus-eluting stent: should we be cautious? Circulation 109: 701-705
5. Kon H, Sakai H, Otsubo M, Takano H, Okamoto K, Sato T, Kimura T, Inoue K (2011) Contrast staining outside the sirolimus-eluting stent leading to coronary aneurysm formation: a case of very late stent thrombosis associated with hypersensitivity reaction. Circ Cardiovasc Interv 4: e1-3
6. Cook S, Ladich E, Nakazawa G, Eshtehardi P, Neidhart M, Vogel R, Togni M, Wenaweser P, Billinger M, Seiler C, Gay S, Meier B, Pichler WJ, Jüni P, Virmani R, Windecker S (2009) Correlation of intravascular ultrasound findings with histopathological analysis of thrombus aspirates in patients with very late drugeluting stent thrombosis. Circulation 120: 391-399
7. Posadas SJ, Pichler WJ (2007) Delayed drug hypersensitivity reactions-new concepts. Clin Exp Allergy 37: 989-999
8. Pichler WJ (2003) Delayed drug hypersensitivity reactions. Ann Intern Med 139: 683-693
9. Nebeker JR, Virmani R, Bennett CL, Hoffman JM, Samore MH, Alvarez J, Davidson CJ, McKoy JM, Raisch DW, Whisenant BK, Yarnold PR, Belknap SM, West DP, Gage JE, Morse RE, Gligoric G, Davidson L, Feldman MD (2006) Hypersensitivity cases associated with drug-eluting coronary stents: a review of available cases from the Research on Adverse Drug Events and Reports (RADAR) project. J Am Coll Cardiol 47: 175-181
10. Goto K, Shiode N, Shirota K, Fukuda Y, Kitamura F, Tominaga K, Kato Y, Miura H, Inoue K, Nobuyoshi M (2009) Pathological finding of sirolimus-eluting stent (SES) restenosis lesion with black hole appearance on intravascular ultrasound. Circ J 73: 1969-1971
11. Fukumoto Y, Shimokawa H, Ito A, Kadokami T, Yonemitsu Y, Aikawa M, Owada MK, Egashira K, Sueishi K, Nagai R, Yazaki Y, Takeshita A (1997) Inflammatory cytokines cause coronary arteriosclerosis-like changes and alterations in the smooth-muscle phenotypes in pigs. J Cardiovasc Pharmacol 29: 222-231
12. Costa MA, Simon DI (2005) Molecular basis of restenosis and drug-eluting stents. Circulation 111: 2257-2273
13. Inoue T, Node K (2009) Molecular basis of restenosis and novel issues of drug-eluting stents. Circ J 73: 615-621
14. Ari H, Ari S, Erdoǧan E, Tiryakioǧlu O, Ustündaǧ Y, Huysal K, Koca V, Bozat T (2010) A novel predictor of restenosis and adverse cardiac events: asymmetric dimethylarginine. Heart Vessels 25: 19-26
15. Alfonso F, Pérez-Vizcayno MJ, Ruiz M, Suárez A, Cazares M, Hernández R, Escaned J, Bañuelos C, Jiménez-Quevedo P, Macaya C (2009) Coronary aneurysms after drug-eluting stent implantation: clinical, angiographic, and intravascular ultrasound findings. J Am Coll Cardiol 53: 2053-2060