Na+/h+ exchange inhibitor SM-20220 attenuates leukocyte adhesion induced by ischemia-reperfusion

Journal of Cardiovascular Pharmacology

Volumn 37, Issue 6, 2001, Pages 668-677

  Horikawa, Naotsugu ^a   Kuribayashi, Yoshikazu ^a   Matsui, Kazuki ^a,b   Kawamura, Nobuko ^a   Ohashi, Naohito ^a  

^a Pharmaceutical Research Division   (Japan)

^b DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

Author keywords

Brain damage; Leukocyte adhesion; Myeloperoxidase; Na+ H+ exchanger; SM 20220

Indexed keywords

ANTIPORTER; SM 20220; SODIUM PROTON EXCHANGE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL INTERACTION; CONTROLLED STUDY; ENDOTHELIUM CELL; HEART MUSCLE REPERFUSION; LEUKOCYTE ADHERENCE; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; PRIORITY JOURNAL; PROTON SODIUM EXCHANGE; RAT; REPERFUSION INJURY;

AMIDES; ANIMALS; CELL ADHESION; ENDOTHELIUM, VASCULAR; INDOLES; INFARCTION, MIDDLE CEREBRAL ARTERY; LEUKOCYTES; MALE; MESENTERY; PEROXIDASE; RATS; RATS, WISTAR; REPERFUSION INJURY; SODIUM-HYDROGEN ANTIPORTER;

EID: 0035012340     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200106000-00004     Document Type: Article

References (2)

1. + exchangers of mammalian cells. J Biol Chem 1997;272:22373-6.
2. Levitsky J, Gurell D, Frishman WH. Sodium ion/hydrogen ion exchange inhibition: a new pharmacologic approach to myocardial ischemia and reperfusion injury. J Clin Pharmacol 1998;38:887-97.