-
1
-
-
0027232953
-
Modulation of alpha 1-adrenoceptors in rat left ventricle by ischaemia and acyl carnitines: Protection by ranolazine
-
Allely, M.C., Brown, C.M., Kenny, B.A., Kilpatrick, A.T., Martin, A., Spedding, M., 1993. Modulation of alpha 1-adrenoceptors in rat left ventricle by ischaemia and acyl carnitines: protection by ranolazine. J. Cardiovasc. Pharmacol. 21, 869-873.
-
(1993)
J. Cardiovasc. Pharmacol.
, vol.21
, pp. 869-873
-
-
Allely, M.C.1
Brown, C.M.2
Kenny, B.A.3
Kilpatrick, A.T.4
Martin, A.5
Spedding, M.6
-
2
-
-
4944257316
-
Electrophysiologic properties and antiarrhythmic actions of a novel antianginal agent
-
Antzelevitch, C., Belardinelli, L., Wu, L., Fraser, H., Zygmunt, A.C., Burashnikov, A., Di Diego, J.M., Fish, J.M., Cordeiro, J.M., Goodrow Jr., R.J., Scornik, F., Perez, G., 2004a. Electrophysiologic properties and antiarrhythmic actions of a novel antianginal agent. J. Cardiovasc. Pharmacol. Ther. 9 (Suppl. 1), S65-S83.
-
(2004)
J. Cardiovasc. Pharmacol. Ther.
, vol.9
, Issue.SUPPL. 1
-
-
Antzelevitch, C.1
Belardinelli, L.2
Wu, L.3
Fraser, H.4
Zygmunt, A.C.5
Burashnikov, A.6
Di Diego, J.M.7
Fish, J.M.8
Cordeiro, J.M.9
Goodrow Jr., R.J.10
Scornik, F.11
Perez, G.12
-
3
-
-
4344577023
-
Electrophysiological effects of ranolazine, a novel antianginal agent with antiarrhythmic properties
-
Antzelevitch, C., Belardinelli, L., Zygmunt, A.C., Burashnikov, A., Di Diego, J.M., Fish, J.M., Cordeiro, J.M., Thomas, G., 2004b. Electrophysiological effects of ranolazine, a novel antianginal agent with antiarrhythmic properties. Circulation 110, 904-910.
-
(2004)
Circulation
, vol.110
, pp. 904-910
-
-
Antzelevitch, C.1
Belardinelli, L.2
Zygmunt, A.C.3
Burashnikov, A.4
Di Diego, J.M.5
Fish, J.M.6
Cordeiro, J.M.7
Thomas, G.8
-
4
-
-
33745368556
-
Inhibition of the late sodium current as a potential cardioprotective principle: Effects of the late sodium current inhibitor ranolazine
-
Belardinelli, L., Shryock, J.C., Fraser, H., 2006. Inhibition of the late sodium current as a potential cardioprotective principle: effects of the late sodium current inhibitor ranolazine. Heart 92 (Suppl. 4), iv6-iv14.
-
(2006)
Heart
, vol.92
, Issue.SUPPL. 4
-
-
Belardinelli, L.1
Shryock, J.C.2
Fraser, H.3
-
5
-
-
0036885781
-
Measuring antianginal drug efficacy using exercise testing for chronic angina: Improved exercise performance with ranolazine, a pFOX inhibitor
-
Chaitman, B.R., 2002. Measuring antianginal drug efficacy using exercise testing for chronic angina: improved exercise performance with ranolazine, a pFOX inhibitor. Curr. Probl. Cardiol. 27, 527-555.
-
(2002)
Curr. Probl. Cardiol.
, vol.27
, pp. 527-555
-
-
Chaitman, B.R.1
-
6
-
-
0348129532
-
Effects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina: A randomized controlled trial
-
Chaitman, B.R., Pepine, C.J., Parker, J.O., Skopal, J., Chumakova, G., Kuch, J., Wang, W., Skettino, S.L., Wolff, A.A., 2004a. Effects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina: a randomized controlled trial. JAMA 291, 309-316.
-
(2004)
JAMA
, vol.291
, pp. 309-316
-
-
Chaitman, B.R.1
Pepine, C.J.2
Parker, J.O.3
Skopal, J.4
Chumakova, G.5
Kuch, J.6
Wang, W.7
Skettino, S.L.8
Wolff, A.A.9
-
7
-
-
11144356285
-
Anti-ischemic effects and long-term survival during ranolazine monotherapy in patients with chronic severe angina
-
Chaitman, B.R., Skettino, S.L., Parker, J.O., Hanley, P., Meluzin, J., Kuch, J., Pepine, C.J., Wang, W., Nelson, J.J., Hebert, D.A., Wolff, A.A., 2004b. Anti-ischemic effects and long-term survival during ranolazine monotherapy in patients with chronic severe angina. J. Am. Coll. Cardiol. 43, 1375-1382.
-
(2004)
J. Am. Coll. Cardiol.
, vol.43
, pp. 1375-1382
-
-
Chaitman, B.R.1
Skettino, S.L.2
Parker, J.O.3
Hanley, P.4
Meluzin, J.5
Kuch, J.6
Pepine, C.J.7
Wang, W.8
Nelson, J.J.9
Hebert, D.A.10
Wolff, A.A.11
-
8
-
-
0037382775
-
Partial fatty acid oxidation (pFOX) inhibition: A new therapy for chronic stable angina
-
Conti, C.R., 2003. Partial fatty acid oxidation (pFOX) inhibition: a new therapy for chronic stable angina. Clin. Cardiol. 26, 161-162.
-
(2003)
Clin. Cardiol.
, vol.26
, pp. 161-162
-
-
Conti, C.R.1
-
9
-
-
44949100421
-
Is ranolazine an antiarrhythmic drug?
-
Eckhardt, L.L., Teelin, T.C., January, C.T., 2008. Is ranolazine an antiarrhythmic drug? Am. J. Physiol. Heart Circ. Physiol. 294, H1989-H1991.
-
(2008)
Am. J. Physiol. Heart Circ. Physiol.
, vol.294
-
-
Eckhardt, L.L.1
Teelin, T.C.2
January, C.T.3
-
10
-
-
0035080560
-
Evidence that ranolazine behaves as a weak beta1- and beta2-adrenoceptor antagonist in the cat cardiovascular system
-
Letienne, R., Vie, B., Puech, A., Vieu, S., Le Grand, B., John, G.W., 2001. Evidence that ranolazine behaves as a weak beta1- and beta2-adrenoceptor antagonist in the cat cardiovascular system. Naunyn Schmiedebergs Arch. Pharmacol. 363, 464-471.
-
(2001)
Naunyn Schmiedebergs Arch. Pharmacol.
, vol.363
, pp. 464-471
-
-
Letienne, R.1
Vie, B.2
Puech, A.3
Vieu, S.4
Le Grand, B.5
John, G.W.6
-
11
-
-
20844460476
-
Raloxifene relaxes rat intrarenal arteries by inhibiting Ca2+ influx
-
Leung, F.P., Yao, X., Lau, C.W., Ko, W.H., Lu, L., Huang, Y., 2005. Raloxifene relaxes rat intrarenal arteries by inhibiting Ca2+ influx. Am. J. Physiol. Renal Physiol. 289, F137-F144.
-
(2005)
Am. J. Physiol. Renal Physiol.
, vol.289
-
-
Leung, F.P.1
Yao, X.2
Lau, C.W.3
Ko, W.H.4
Lu, L.5
Huang, Y.6
-
12
-
-
0036152190
-
-
Clinical trials update: The Heart Protection Study, IONA, CARISA, ENRICHD, ACUTE, ALIVE,MADIT II and REMATCH. Impact of Nicorandil on Angina. Combination Assessment of Ranolazine in Stable Angina. ENhancing Recovery in Coronary Heart Disease patients. Assessment of Cardioversion Using Transoesophageal Echocardiography. AzimiLide post-Infarct surVival Evaluation. Randomised Evaluation of Mechanical Assistance for Treatment of Chronic Heart failure
-
Louis, A.A., Manousos, I.R., Coletta, A.P., Clark, A.L., Cleland, J.G., 2002. Clinical trials update: The Heart Protection Study, IONA, CARISA, ENRICHD, ACUTE, ALIVE,MADIT II and REMATCH. Impact of Nicorandil on Angina. Combination Assessment of Ranolazine in Stable Angina. ENhancing Recovery in Coronary Heart Disease patients. Assessment of Cardioversion Using Transoesophageal Echocardiography. AzimiLide post-Infarct surVival Evaluation. Randomised Evaluation of Mechanical Assistance for Treatment of Chronic Heart failure. Eur. J. Heart Fail. 4, 111-116.
-
(2002)
Eur. J. Heart Fail.
, vol.4
, pp. 111-116
-
-
Louis, A.A.1
Manousos, I.R.2
Coletta, A.P.3
Clark, A.L.4
Cleland, J.G.5
-
13
-
-
0032983310
-
A controlled trial with a novel anti-ischemic agent, ranolazine, in chronic stable angina pectoris that is responsive to conventional antianginal agents
-
Ranolazine Study Group
-
Pepine, C.J., Wolff, A.A., 1999. A controlled trial with a novel anti-ischemic agent, ranolazine, in chronic stable angina pectoris that is responsive to conventional antianginal agents. Ranolazine Study Group. Am. J. Cardiol. 84, 46-50.
-
(1999)
Am. J. Cardiol.
, vol.84
, pp. 46-50
-
-
Pepine, C.J.1
Wolff, A.A.2
-
14
-
-
0036936426
-
Ranolazine, a partial fatty acid oxidation (pFOX) inhibitor, improves left ventricular function in dogs with chronic heart failure
-
Sabbah, H.N., Chandler, M.P., Mishima, T., Suzuki, G., Chaudhry, P., Nass, O., Biesiadecki, B.J., Blackburn, B., Wolff, A., Stanley, W.C., 2002. Ranolazine, a partial fatty acid oxidation (pFOX) inhibitor, improves left ventricular function in dogs with chronic heart failure. J. Card. Fail. 8, 416-422.
-
(2002)
J. Card. Fail.
, vol.8
, pp. 416-422
-
-
Sabbah, H.N.1
Chandler, M.P.2
Mishima, T.3
Suzuki, G.4
Chaudhry, P.5
Nass, O.6
Biesiadecki, B.J.7
Blackburn, B.8
Wolff, A.9
Stanley, W.C.10
-
15
-
-
40949140176
-
The cardiac persistent sodium current: An appealing therapeutic target?
-
Saint, D.A., 2008. The cardiac persistent sodium current: an appealing therapeutic target? Br. J. Pharmacol. 153, 1133-1142.
-
(2008)
Br J. Pharmacol.
, vol.153
, pp. 1133-1142
-
-
Saint, D.A.1
-
16
-
-
35148850168
-
Effect of ranolazine, an antianginal agent with novel electrophysiological properties, on the incidence of arrhythmias in patients with non ST-segment elevation acute coronary syndrome: Results from the Metabolic Efficiency with Ranolazine for Less Ischemia in Non ST-Elevation Acute Coronary Syndrome Thrombolysis in Myocardial Infarction 36 (MERLIN-TIMI 36) randomized controlled trial
-
Scirica, B.M., Morrow, D.A., Hod, H., Murphy, S.A., Belardinelli, L., Hedgepeth, C.M., Molhoek, P., Verheugt, F.W., Gersh, B.J., McCabe, C.H., Braunwald, E., 2007. Effect of ranolazine, an antianginal agent with novel electrophysiological properties, on the incidence of arrhythmias in patients with non ST-segment elevation acute coronary syndrome: results from the Metabolic Efficiency With Ranolazine for Less Ischemia in Non ST-Elevation Acute Coronary Syndrome Thrombolysis in Myocardial Infarction 36 (MERLIN-TIMI 36) randomized controlled trial. Circulation 116, 1647-1652.
-
(2007)
Circulation
, vol.116
, pp. 1647-1652
-
-
Scirica, B.M.1
Morrow, D.A.2
Hod, H.3
Murphy, S.A.4
Belardinelli, L.5
Hedgepeth, C.M.6
Molhoek, P.7
Verheugt, F.W.8
Gersh, B.J.9
McCabe, C.H.10
Braunwald, E.11
-
17
-
-
77952762318
-
The endothelial saga: The past, the present, the future
-
Serban, D.N., Nilius, B., Vanhoutte, P.M., 2010. The endothelial saga: the past, the present, the future. Pflugers Arch. 459, 787-792.
-
(2010)
Pflugers Arch.
, vol.459
, pp. 787-792
-
-
Serban, D.N.1
Nilius, B.2
Vanhoutte, P.M.3
-
18
-
-
3242778566
-
Antagonism by ranolazine of the pro-arrhythmic effects of increasing late INa in guinea pig ventricular myocytes
-
Song, Y., Shryock, J.C., Wu, L., Belardinelli, L., 2004. Antagonism by ranolazine of the pro-arrhythmic effects of increasing late INa in guinea pig ventricular myocytes. J. Cardiovasc. Pharmacol. 44, 192-199.
-
(2004)
J. Cardiovasc. Pharmacol.
, vol.44
, pp. 192-199
-
-
Song, Y.1
Shryock, J.C.2
Wu, L.3
Belardinelli, L.4
-
19
-
-
3042595438
-
Raloxifene relaxes rat cerebral arteries in vitro and inhibits L-type voltage-sensitive Ca2+ channels
-
Tsang, S.Y., Yao, X., Essin, K., Wong, C.M., Chan, F.L., Gollasch, M., Huang, Y., 2004. Raloxifene relaxes rat cerebral arteries in vitro and inhibits L-type voltage-sensitive Ca2+ channels. Stroke 35, 1709-1714.
-
(2004)
Stroke
, vol.35
, pp. 1709-1714
-
-
Tsang, S.Y.1
Yao, X.2
Essin, K.3
Wong, C.M.4
Chan, F.L.5
Gollasch, M.6
Huang, Y.7
-
20
-
-
3342882854
-
Antiarrhythmic effects of ranolazine in a guinea pig in vitro model of long-QT syndrome
-
Wu, L., Shryock, J.C., Song, Y., Li, Y., Antzelevitch, C., Belardinelli, L., 2004. Antiarrhythmic effects of ranolazine in a guinea pig in vitro model of long-QT syndrome. J. Pharmacol. Exp. Ther. 310, 599-605.
-
(2004)
J. Pharmacol. Exp. Ther.
, vol.310
, pp. 599-605
-
-
Wu, L.1
Shryock, J.C.2
Song, Y.3
Li, Y.4
Antzelevitch, C.5
Belardinelli, L.6
-
21
-
-
71049154222
-
Synthesis of ranolazine metabolites and their anti-myocardial ischemia activities
-
Yao, Z., Gong, S., Guan, T., Li, Y., Wu, X., Sun, H., 2009. Synthesis of ranolazine metabolites and their anti-myocardial ischemia activities. Chem. Pharm. Bull.(Tokyo) 57, 1218-1222.
-
(2009)
Chem. Pharm. Bull.(Tokyo)
, vol.57
, pp. 1218-1222
-
-
Yao, Z.1
Gong, S.2
Guan, T.3
Li, Y.4
Wu, X.5
Sun, H.6
-
22
-
-
79958284578
-
Antiadrenergic and hemodynamic effects of ranolazine in conscious dogs
-
Zhao, G., Walsh, E., Shryock, J.C., Messina, E., Wu, Y., Zeng, D., Xu, X., Ochoa, M., Baker, S.P., Hintze, T.H., Belardinelli, L., 2011. Antiadrenergic and hemodynamic effects of ranolazine in conscious dogs. J. Cardiovasc. Pharmacol. 57, 639-647.
-
(2011)
J. Cardiovasc. Pharmacol.
, vol.57
, pp. 639-647
-
-
Zhao, G.1
Walsh, E.2
Shryock, J.C.3
Messina, E.4
Wu, Y.5
Zeng, D.6
Xu, X.7
Ochoa, M.8
Baker, S.P.9
Hintze, T.H.10
Belardinelli, L.11
|