Regulation of asthmatic airway relaxation by estrogen and heat shock protein 90

Journal of Cellular Physiology

Volumn 227, Issue 8, 2012, Pages 3036-3043

  Intapad, S ^a,b   Dimitropoulou, C ^a   Snead, C ^a   Piyachaturawat, P ^b   Catravas, J D ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b Mahidol University   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR BETA; GLYCERYL TRINITRATE; HEAT SHOCK PROTEIN 90; NITRIC OXIDE DONOR; NITROPRUSSIDE SODIUM; RADICICOL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTHMA; CONTROLLED STUDY; HUMAN; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRACHEA;

ANIMALS; ASTHMA; CELLS, CULTURED; ESTRADIOL; ESTROGENS; HSP90 HEAT-SHOCK PROTEINS; HUMANS; MACROLIDES; MICE; MICE, INBRED C57BL; MUSCLE RELAXATION; MUSCLE, SMOOTH; NITRIC OXIDE; NITRIC OXIDE DONORS; NITROGLYCERIN; NITROPRUSSIDE; ORGAN CULTURE TECHNIQUES; SERUM; TRACHEA;

EID: 84860436572     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.23045     Document Type: Article

References (40)

1. Austin CE. 2000. Chronic and acute effects of oestrogens on vascular contractility. J Hypertens 18: 1365-1378.
2. Bagatell R, Khan O, Paine-Murrieta G, Taylor CW, Akinaga S, Whitesell L. 2001. Destabilization of steroid receptors by heat shock protein 90-binding drugs: A ligand-independent approach to hormonal therapy of breast cancer. Clin Cancer Res 7: 2076-2084.
3. Bousquet J, Jeffery PK, Busse WW, Johnson M, Vignola AM. 2000. Asthma. From bronchoconstriction to airways inflammation and remodeling. Am J Respir Crit Care Med 161: 1720-1745.
4. Carey MA, Card JW, Bradbury JA, Moorman MP, Haykal-Coates N, Gavett SH, Graves JP, Walker VR, Flake GP, Voltz JW, Zhu D, Jacobs ER, Dakhama A, Larsen GL, Loader JE, Gelfand EW, Germolec DR, Korach KS, Zeldin DC. 2007. Spontaneous airway hyperresponsiveness in estrogen receptor-{alpha}-deficient mice. Am J Respir Crit Care Med 175: 126-135.
5. Cary SP, Winger JA, Marletta MA. 2005. Tonic and acute nitric oxide signaling through soluble guanylate cyclase is mediated by nonheme nitric oxide, ATP, and GTP. Proc Natl Acad Sci USA 102: 13064-13069.
6. Couse JF, Lindzey J, Grandien K, Gustafsson J-A, Korach KS. 1997. Tissue distribution and quantitative analysis of estrogen receptor-{alpha} (ER{alpha}) and estrogen receptor-{beta} (ER{beta}) messenger ribonucleic acid in the wild-type and ER{alpha}-knockout mouse. Endocrinology 138: 4613-4621.
7. Cross S. 1994. Asthma and the menstrual cycle (continuing education credit). Nurs Stand 8: 22-26 (quiz 27-28).
8. Degano B, Prevost MC, Berger P, Molimard M, Pontier S, Rami J, Escamilla R. 2001. Estradiol decreases the acetylcholine-elicited airway reactivity in ovariectomized rats through an increase in epithelial acetylcholinesterase activity. Am J Respir Crit Care Med 164: 1849-1854.
9. Devin-Leclerc J, Meng X, Delahaye F, Leclerc P, Baulieu E-E, Catelli M-G. 1998. Interaction and dissociation by ligands of estrogen receptor and Hsp90: The Antiestrogen RU 58668 induces a protein synthesis-dependent clustering of the receptor in the cytoplasm. Mol Endocrinol 12: 842-854.
10. Dijkstra A, Howard TD, Vonk JM, Ampleford EJ, Lange LA, Bleecker ER, Meyers DA, Postma DS. 2006. Estrogen receptor 1 polymorphisms are associated with airway hyperresponsiveness and lung function decline, particularly in female subjects with asthma. J Allergy Clin Immunol 117: 604-611.
11. Dimitropoulou C, Drakopanagiotakis F, Chatterjee A, Snead C, Catravas JD. 2009. Estrogen replacement therapy prevents airway dysfunction in a murine model of allergen-induced asthma. Lung 187: 116-127.
12. Dimitropoulou C, White RE, Ownby DR, Catravas JD. 2005. Estrogen reduces carbachol-induced constriction of asthmatic airways by stimulating large-conductance voltage and calcium-dependent potassium channels. Am J Respir Cell Mol Biol 32: 239-247.
13. Foster PS, Goldie RG, Paterson JW. 1983. Effect of steroids on beta-adrenoceptor-mediated relaxation of pig bronchus. Br J Pharmacol 78: 441-445.
14. Gaston B, Drazen JM, Loscalzo J, Stamler JS. 1994. The biology of nitrogen oxides in the airways. Am J Respir Crit Care Med 149: 538-551.
15. Haas E, Bhattacharya I, Brailoiu E, Damjanovic M, Brailoiu GC, Gao X, Mueller-Guerre L, Marjon NA, Gut A, Minotti R, Meyer MR, Amann K, Ammann E, Perez-Dominguez A, Genoni M, Clegg DJ, Dun NJ, Resta TC, Prossnitz ER, Barton M. 2009. Regulatory role of G protein-coupled estrogen receptor for vascular function and obesity. Circ Res 104: 288-291.
16. Hakonarson H, Herrick DJ, Grunstein MM. 1995. Mechanism of impaired beta-adrenoceptor responsiveness in atopic sensitized airway smooth muscle. Am J Physiol 269: L645-L652.
17. Hogan AM, Kennelly R, Collins D, Baird AW, Winter DC. 2009. Oestrogen inhibits human colonic motility by a non-genomic cell membrane receptor-dependent mechanism. Br J Surg 96: 817-822.
18. Jensen-Jarolim E, Untersmayr E. 2008. Gender-medicine aspects in allergology. Allergy 63: 610-615.
19. Keung W, Chan ML, Ho EY, Vanhoutte PM, Man RY. 2011. Non-genomic activation of adenylyl cyclase and protein kinase G by 17beta-estradiol in vascular smooth muscle of the rat superior mesenteric artery. Pharmacol Res 64: 509-516.
20. Lancaster J Jr, Langrehr J, Bergonia H, Murase N, Simmons R, Hoffman R. 1992. EPR detection of heme and nonheme iron-containing protein nitrosylation by nitric oxide during rejection of rat heart allograft. J Biol Chem 267: 10994-10998.
21. Larsson A-K, Back M, Lundberg J, Dahlen S-E. 2009. Specific mediator inhibition by the NO donors SNP and NCX 2057 in the peripheral lung: Implications for allergen-induced bronchoconstriction. Respiratory Research 10: 46.
22. Lindsey SH, Cohen JA, Brosnihan KB, Gallagher PE, Chappell MC. 2009. Chronic treatment with the G protein-coupled receptor 30 agonist G-1 decreases blood pressure in ovariectomized mRen2.Lewis Rats. Endocrinology 150: 3753-3758.
23. Martin J, Duguet A, Eidelman D. 2000. The contribution of airway smooth muscle to airway narrowing and airway hyperresponsiveness in disease. Eur Respir J 16: 349-354.
24. Montgomery S, Shaw L, Pantelides N, Taggart M, Austin C. 2003. Acute effects of oestrogen receptor subtype-specific agonists on vascular contractility. Br J Pharmacol 139: 1249-1253.
25. Mullershausen F, Russwurm M, Friebe A, Koesling D. 2004. Inhibition of phosphodiesterase type 5 by the activator of nitric oxide-sensitive guanylyl cyclase BAY41-2272. Circulation 109: 1711-1713.
26. Nilsson BO, Olde B, Leeb-Lundberg LM. 2011. G protein-coupled oestrogen receptor 1 (GPER1)/GP R30: A new player in cardiovascular and metabolic oestrogenic signalling. Br J Pharmacol 163: 1131-1139.
27. Papapetropoulos A, Simoes DC, Xanthou G, Roussos C, Gratziou C. 2006. Soluble guanylyl cyclase expression is reduced in allergic asthma. Am J Physiol 290: L179-L184.
28. Papapetropoulos A, Zhou Z, Gerassimou C, Yetik G, Venema RC, Roussos C, Sessa WC, Catravas JD. 2005. Interaction between the 90-kDa heat shock protein and soluble guanylyl cyclase: Physiological significance and mapping of the domains mediating binding. Mol Pharmacol 68: 1133-1141.
29. Redington AE, Meng Q-H, Springall DR, Evans TJ, Creminon C, Maclouf J, Holgate ST, Howarth PH, Polak JM. 2001. Increased expression of inducible nitric oxide synthase and cyclo-oxygenase-2 in the airway epithelium of asthmatic subjects and regulation by corticosteroid treatment. Thorax 56: 351-357.
30. Ricciardolo FL, Sterk PJ, Gaston B, Folkerts G. 2004. Nitric oxide in health and disease of the respiratory system. Physiol Rev 84: 731-765.
31. Russwurm M, Koesling D. 2004a. Guanylyl cyclase: NO hits its target. Biochem Soc Sym 51-63.
32. Russwurm M, Koesling D. 2004b. NO activation of guanylyl cyclase. EMBO J 23: 4443-4450.
33. Satouchi M, Maeda H, Yu Y, Yokoyama M. 1996. Clinical significance of the increased peak levels of exhaled nitric oxide in patients with bronchial asthma. Intern Med 35: 270-275.
34. Seow CY, Schellenberg RR, Pare PD. 1998. Structural and functional changes in the airway smooth muscle of asthmatic subjects. Am J Respir Crit Care Med 158: S179-S186.
35. Shore SA, Moore PE. 2003. Regulation of beta-adrenergic responses in airway smooth muscle. Respir Physiol Neurobiol 137: 179-195.
36. Smith D, Toft D. 1993. Steroid receptors and their associated proteins. Mol Endocrinol 7: 4-11. DOI: 10.1210/me.7.1.4.
37. Thomas P, Pang Y, Filardo EJ, Dong J. 2005. Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells. Endocrinology 146: 624-632.
38. Venema RC, Venema VJ, Ju H, Harris MB, Snead C, Jilling T, Dimitropoulou C, Maragoudakis ME, Catravas JD. 2003. Novel complexes of guanylate cyclase with heat shock protein 90 and nitric oxide synthase. Am J Physiol Heart Circ Physiol 285: H669-H678.
39. Yetik-Anacak G, Xia T, Dimitropoulou C, Venema RC, Catravas JD. 2006. Effects of hsp90 binding inhibitors on sGC-mediated vascular relaxation. Am J Physiol Heart Circ Physiol 291: H260-H268.
40. Yu X, Ma H, Barman SA, Sellers M, Stallone JN, Prossnitz ER, White RE, Han G. Activation of G protein-coupled estrogen receptor (GPER) induces endothelium-independent relaxation of coronary artery smooth muscle. Am J Physiol Endocrinol Metab 2011 [Epub ahead of print].