Antibodies for assessing circadian clock proteins in the rodent suprachiasmatic nucleus

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  LeSauter, Joseph ^a   Lambert, Christopher M ^b   Robotham, Margaret R ^a   Model, Zina ^a   Silver, Rae ^a,c,d   Weaver, David R ^b  

^a Barnard College of Columbia University   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c Och Spine at New York Presbyterian Hospitals   (United States)

^d NewYork Presbyterian Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CIRCADIAN RHYTHM SIGNALING PROTEIN; PER1 PROTEIN; PER2 PROTEIN; PROTEIN ANTIBODY; PROTEIN BMAL1; TRANSCRIPTION FACTOR CLOCK; ANTIBODY;

ANIMAL CELL; ANIMAL TISSUE; ANTIBODY LABELING; ANTIBODY PRODUCTION; ANTIBODY SPECIFICITY; ANTIGEN ANTIBODY COMPLEX; ARTICLE; CIRCADIAN RHYTHM; CONTROLLED STUDY; GENE DISRUPTION; HAMSTER; IMMUNOASSAY; IMMUNOCYTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TARGETING; SUPRACHIASMATIC NUCLEUS; ANIMAL; C57BL MOUSE; CYTOLOGY; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; STAINING; SYRIAN HAMSTER;

CRICETINAE; MUS; RODENTIA;

ANIMALS; ANTIBODIES; CIRCADIAN CLOCKS; CLOCK PROTEINS; CRICETINAE; MALE; MESOCRICETUS; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; STAINING AND LABELING; SUPRACHIASMATIC NUCLEUS;

EID: 84860427576     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0035938     Document Type: Article

References (46)

1. Maywood ES, Reddy AB, Wong GK, O'Neill JS, O'Brien JA, et al. (2006) Synchronization and maintenance of timekeeping in suprachiasmatic circadian clock cells by neuropeptidergic signaling. Curr Biol 16: 599-605.
2. Loh DH, Dragich JM, Kudo T, Schroeder AM, Nakamura TJ, et al. (2011) Effects of vasoactive intestinal peptide genotype on circadian gene expression in the suprachiasmatic nucleus and peripheral organs. J Biol Rhythms 26: 200-209.
3. Welsh DK, Takahashi JS, Kay SA, (2010) Suprachiasmatic nucleus: cell autonomy and network properties. Annu Rev Physiol 72: 551-577.
4. Reppert SM, Weaver DR, (2002) Coordination of circadian timing in mammals. Nature 418: 935-941.
5. Lee C, Etchegaray JP, Cagampang FR, Loudon AS, Reppert SM, (2001) Posttranslational mechanisms regulate the mammalian circadian clock. Cell 107: 855-867.
6. Meng QJ, Logunova L, Maywood ES, Gallego M, Lebiecki J, et al. (2008) Setting clock speed in mammals: the CK1 epsilon tau mutation in mice accelerates circadian pacemakers by selectively destabilizing PERIOD proteins. Neuron 58: 78-88.
7. Etchegaray JP, Machida KK, Noton E, Constance CM, Dallmann R, et al. (2009) Casein kinase 1 delta regulates the pace of the mammalian circadian clock. Mol Cell Biol 29: 3853-3866.
8. Walton KM, Fisher K, Rubitski D, Marconi M, Meng QJ, et al. (2009) Selective inhibition of casein kinase 1 epsilon minimally alters circadian clock period. J Pharmacol Exp Ther 330: 430-439.
9. Lee HM, Chen R, Kim H, Etchegaray JP, Weaver DR, et al. (2011) The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1. Proc Natl Acad Sci USA 108: 16451-16456.
10. Maywood ES, Chesham JE, Meng QJ, Nolan PM, Loudon AS, et al. (2011) Tuning the period of the mammalian circadian clock: additive and independent effects of CK1epsilonTau and Fbxl3Afh mutations on mouse circadian behavior and molecular pacemaking. J Neurosci 31: 1539-1544.
11. Hastings MH, Field MD, Maywood ES, Weaver DR, Reppert SM, (1999) Differential regulation of mPER1 and mTIM proteins in the mouse suprachiasmatic nuclei: new insights into a core clock mechanism. J Neurosci 19: RC11.
12. Field MD, Maywood ES, O'Brien JA, Weaver DR, Reppert SM, et al. (2000) Analysis of clock proteins in mouse SCN demonstrates phylogenetic divergence of the circadian clockwork and resetting mechanisms. Neuron 25: 437-447.
13. Bae K, Jin X, Maywood ES, Hastings MH, Reppert SM, et al. (2001) Differential functions of mPer1, mPer2, and mPer3 in the SCN circadian clock. Neuron 30: 525-536.
14. LeSauter J, Yan L, Vishnubhotla B, Quintero JE, Kuhlman SJ, et al. (2003) A short half-life GFP mouse model for analysis of suprachiasmatic nucleus organization. Brain Res 964: 279-287.
15. von Gall C, Noton E, Lee C, Weaver DR, (2003) Light does not degrade the constitutively expressed BMAL1 protein in the mouse suprachiasmatic nucleus. Eur J Neurosci 18: 125-133.
16. Munoz M, Peirson SN, Hankins MW, Foster RG, (2005) Long-term constant light induces constitutive elevated expression of mPER2 protein in the murine SCN: a molecular basis for Aschoff's rule? J Biol Rhythms 20: 3-14.
17. DeBruyne JP, Noton E, Lambert CM, Maywood ES, Weaver DR, et al. (2006) A clock shock: mouse CLOCK is not required for circadian oscillator function. Neuron 50: 465-477.
18. Ramanathan C, Nunez AA, Martinez GS, Schwartz MD, Smale L, (2006) Temporal and spatial distribution of immunoreactive PER1 and PER2 proteins in the suprachiasmatic nucleus and peri-suprachiasmatic region of the diurnal grass rat (Arvicanthis niloticus). Brain Res 1073-1074: 348-358.
19. Saper CB, (2009) A guide to the perplexed on the specificity of antibodies. J Histochem Cytochem 57: 1-5.
20. Bunger MK, Wilsbacher LD, Moran SM, Clendenin C, Radcliffe LA, et al. (2000) Mop3 is an essential component of the master circadian pacemaker in mammals. Cell 103: 1009-1017.
21. Shearman LP, Sriram S, Weaver DR, Maywood ES, Chaves I, et al. (2000) Interacting molecular loops in the mammalian circadian clock. Science 288: 1013-1019.
22. von Gall C, Garabette ML, Kell CA, Frenzel S, Dehghani F, et al. (2002) Rhythmic gene expression in pituitary depends on heterologous sensitization by the neurohormone melatonin. Nat Neurosci 5: 234-238.
23. Jilg A, Moek J, Weaver DR, Korf HW, Stehle JH, et al. (2005) Rhythms in clock proteins in the mouse pars tuberalis depend on MT1 melatonin receptor signalling. Eur J Neurosci 22: 2845-2854.
24. Sheynzon P, Karolczak M, Dehghani F, Korf HW, (2005) Diurnal variation in CREB phosphorylation and PER1 protein levels in lactotroph cells of melatonin-proficient C3H and melatonin-deficient C57BL mice: similarities and differences. Cell Tissue Res 321: 211-217.
25. Ramanathan C, Nunez AA, Smale L, (2008) Daily rhythms in PER1 within and beyond the suprachiasmatic nucleus of female grass rats (Arvicanthis niloticus). Neuroscience 156: 48-58.
26. Ramanathan C, Smale L, Nunez AA, (2008) Rhythms in expression of PER1 protein in the amygdala and bed nucleus of the stria terminalis of the diurnal grass rat (Arvicanthis niloticus). Neurosci Lett 441: 86-89.
27. Ramanathan C, Stowie A, Smale L, Nunez AA, (2010) Phase preference for the display of activity is associated with the phase of extra-suprachiasmatic nucleus oscillators within and between species. Neuroscience 170: 758-772.
28. Lemos DR, Goodspeed L, Tonelli L, Antoch MP, Ojeda SR, et al. (2007) Evidence for circadian regulation of activating transcription factor 5 but not tyrosine hydroxylase by the chromaffin cell clock. Endocrinology 148: 5811-5821.
29. Resuehr HE, Resuehr D, Olcese J, (2009) Induction of mPer1 expression by GnRH in pituitary gonadotrope cells involves EGR-1. Mol Cell Endocrinol 311: 120-125.
30. Tavakoli-Nezhad M, Tao-Cheng JH, Weaver DR, Schwartz WJ, (2007) PER1-like immunoreactivity in oxytocin cells of the hamster hypothalamo-neurohypophyseal system. J Biol Rhythms 22: 81-84.
31. Yan L, Silver R, (2004) Resetting the brain clock: time course and localization of mPER1 and mPER2 protein expression in suprachiasmatic nuclei during phase shifts. Eur J Neurosci 19: 1105-1109.
32. Yasuo S, von Gall C, Weaver DR, Korf HW, (2008) Rhythmic expression of clock genes in the ependymal cell layer of the third ventricle of rodents is independent of melatonin signaling. Eur J Neurosci 28: 2443-2450.
33. Verwey M, Lam GY, Amir S, (2009) Circadian rhythms of PERIOD1 expression in the dorsomedial hypothalamic nucleus in the absence of entrained food-anticipatory activity rhythms in rats. Eur J Neurosci 29: 2217-2222.
34. Bur IM, Zouaoui S, Fontanaud P, Coutry N, Molino F, et al. (2010) The comparison between circadian oscillators in mouse liver and pituitary gland reveals different integration of feeding and light schedules. PLoS One 5: e15316.
35. Hood S, Cassidy P, Cossette MP, Weigl Y, Verwey M, et al. (2010) Endogenous dopamine regulates the rhythm of expression of the clock protein PER2 in the rat dorsal striatum via daily activation of D2 dopamine receptors. J Neurosci 30: 14046-14058.
36. Ramanathan C, Stowie A, Smale L, Nunez A, (2010) PER2 rhythms in the amygdala and bed nucleus of the stria terminalis of the diurnal grass rat (Arvicanthis niloticus). Neurosci Lett 473: 220-223.
37. Schrader JA, Nunez AA, Smale L, (2010) Changes in and dorsal to the rat suprachiasmatic nucleus during early pregnancy. Neuroscience 171: 513-523.
38. Schrader JA, Nunez AA, Smale L, (2011) Site-specific changes in brain extra-SCN oscillators during early pregnancy in the rat. J Biol Rhythms 26: 363-367.
39. Quintero JE, Kuhlman SJ, McMahon DG, (2003) The biological clock nucleus: a multiphasic oscillator network regulated by light. J Neurosci 23: 8070-8076.
40. Foley NC, Tong TY, Foley D, LeSauter J, Welsh DK, et al. (2011) Characterization of orderly spatiotemporal patterns of clock gene activation in mammalian suprachiasmatic nucleus. Eur J Neurosci 33: 1851-1865.
41. Maywood ES, O'Brien JA, Hastings MH, (2003) Expression of mCLOCK and other circadian clock-relevant proteins in the mouse suprachiasmatic nuclei. J Neuroendocrinol 15: 329-334.
42. Wyse CA, Coogan AN, (2010) Impact of aging on diurnal expression patterns of CLOCK and BMAL1 in the mouse brain. Brain Res 1337: 21-31.
43. Beaule C, Cheng H-YM, (2011) The acetyltransferase CLOCK is dispensible for circadian aftereffects in mice. J Biol Rhythms 26: 561-564.
44. Tamaru T, Isojima Y, Yamada T, Okada M, Nagai K, et al. (2000) Light and glutamate-induced degradation of the circadian oscillating protein BMAL1 during the mammalian clock resetting. J Neurosci 20: 7525-7530.
45. Lamont EW, Robinson B, Stewart J, Amir S, (2005) The central and basolateral nuclei of the amygdala exhibit opposite diurnal rhythms of expression of the clock protein Period2. Proc Natl Acad Sci U S A 102: 4180-4184.
46. Carr AJF, Semikhodskii AG, Loudon ASI, (2000) Partial cloning of Syrian hamster Period 2 gene. GenBank entry AF306648.1. NCBI website. Available: http://www.ncbi.nlm.nih.gov/nuccore/10444524. Accessed 2012 Jan 29.