Development and utilization of activated STAT3 detection assays for screening a library of secreted proteins

Assay and Drug Development Technologies

Volumn 9, Issue 4, 2011, Pages 420-429

  Fursov, Natalie ^a   Gates, Irina V ^a   Panavas, Tadas ^a   Giles Komar, Jill ^a   Powers, Gordon ^a  

^a CENTOCOR INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN GP 130; INTERLEUKIN 6; JANUS KINASE; PEPTIDE LIBRARY; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BIOLOGICAL ACTIVITY; CELL NUCLEUS; CHEMOLUMINESCENCE; CONTROLLED STUDY; CYTOKINE RELEASE; DIMERIZATION; DRUG RESEARCH; DRUG TARGETING; ELECTROCHEMICAL DETECTION; FLUORESCENCE IMAGING; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; LASER SCANNING CYTOMETRY; LIGAND BINDING; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; RELIABILITY;

CELL LINE, TUMOR; CYTOKINE RECEPTOR GP130; DRUG DISCOVERY; FLUORESCENCE; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; INTERLEUKIN-6; JANUS KINASES; PHOSPHORYLATION; PROTEINS; SIGNAL TRANSDUCTION; SMALL MOLECULE LIBRARIES; STAT3 TRANSCRIPTION FACTOR;

EID: 84860419274     PISSN: 1540658X     EISSN: 15578127     Source Type: Journal    
DOI: 10.1089/adt.2010.0348     Document Type: Article

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