Defining the Mer1 and Nam8 meiotic splicing regulons by cDNA rescue

RNA

Volumn 17, Issue 9, 2011, Pages 1648-1654

  Qiu, Zhicheng R ^a   Schwer, Beate ^b   Shuman, Stewart ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

AMA1; MER2; MER3; SPO22

Indexed keywords

AMA1 PROTEIN; COMPLEMENTARY DNA; FUNGAL PROTEIN; MER1 PROTEIN; MER2 PROTEIN; MER3 PROTEIN; MESSENGER RNA PRECURSOR; NAM8 PROTEIN; PCH2 PROTEIN; POLYPEPTIDE; RNA; RRM1 PROTEIN; RRM2 PROTEIN; RRM3 PROTEIN; SPO22 PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DIPLOIDY; GENE EXPRESSION; GENE MUTATION; INTRON; MEIOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN TARGETING; REGULON; RNA BINDING; RNA SPLICING; SACCHAROMYCES CEREVISIAE; SPOROGENESIS; YEAST;

SACCHAROMYCETALES;

EID: 84860412668     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.2792011     Document Type: Article

References (25)

1. Balzer R.J., Henry M.F. 2008. Snu56p is required for Mer1p-activates meiotic splicing. Mol Cell Biol 28: 2497-2508. (Pubitemid 351542352)
2. Cooper K.F., Mallory M.J., Egeland D.B., Jarnik M., Strich R. 2000. Ama1p is a meiosis-specific regulator of the anaphase promoting complex/cyclosome in yeast. Proc Natl Acad Sci 97: 14548-14553. (Pubitemid 32016613)
3. Engebrecht J., Roeder G.S. 1990. MER1, a yeast gene required for chromosome pairing and genetic recombination is induced in meiosis. Mol Cell Biol 10: 2379-2389.
4. Engebrecht J., Voelkel-Meiman K., Roeder G.S. 1991. Meiosis-specific RNA splicing in yeast. Cell 66: 1257-1268. (Pubitemid 121001414)
5. Fabrizio P., Dannenberg J., Dube P., Kastner B., Stark H., Urlaub H., Lührmann R. 2009. The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome. Mol Cell 36: 593-608.
6. Goldstein A.L., McCusker J.H. 1999. Three new dominant drug resistance cassettes for gene disruption in Saccharomyces cerevisiae. Yeast 15: 1541-1553. (Pubitemid 29472165)
7. Gottschalk A., Tang J., Puig O., Salgado J., Neubauer G., Colot H.V., Mann M., Séraphin B., Rosbash M., Lührmann R., et al. 1998. A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins. RNA 4: 374-393. (Pubitemid 28160780)
8. Juneau K., Palm C., Miranda M., Davis R.W. 2007. High-density yeast-tiling array reveals previously undiscovered introns and extensive regulation of meiotic splicing. Proc Natl Acad Sci 104: 1522-1527. (Pubitemid 46214623)
9. Maleki S., Neale M.J., Arora C., Henderson K.A., Keeney S. 2007. Interaction between Mei4, Rec114, and other proteins required for meiotic double-strand break formation in Saccharomyces cerevisiae. Chromosoma 116: 471-486. (Pubitemid 47456915)
10. Munding E.M., Igel A.H., Shiue L., Dorighi K.M., Trevino L.R., Ares M. 2010. Integration of a splicing network within the meiotic gene expression program of Saccharomyces cerevisiae. Genes Dev 24: 2693-2704.
11. Nakagawa T., Ogawa H. 1997. Involvement of the MRE2 gene of yeast in formation of meiosis-specific double-strand breaks and cross-over recombination through RNA splicing. Genes Cells 2: 65-79. (Pubitemid 127688559)
12. Nakagawa T., Ogawa H. 1999. The Saccharomyces cerevisiae MER3 gene, encoding a novel helicase-like protein, is required for crossover control in meiosis. EMBO J 18: 5714-5723. (Pubitemid 29486389)
13. Nandabalan K., Price L., Roeder G.S. 1993. Mutations in U1 snRNA bypass the requirement for a cell type-specific RNA splicing factor. Cell 73: 407-415. (Pubitemid 23123317)
14. Nilsen T.W., Graveley B.R. 2010. Expansion of the eukaryotic proteome by alternative splicing. Nature 463: 457-463.
15. Oelschlaegel T., Schwickart M., Matos J., Bogdanova A., Mamasses A., Havlis J., Shevchenko A., Zachariae W. 2005. The yeast APC/C subunit Mnd2 prevents premature sister chromatid separation triggered by the meiosis-specific APC.C-Ama1. Cell 120: 773-788. (Pubitemid 40568796)
16. Penkner A.M., Prinz S., Ferscha S., Klein F. 2005. Mnd2, an essential antagonist of the anaphase-promoting complex during meiotic prophase. Cell 120: 789-801. (Pubitemid 40568797)
17. Primig M., Williams R.M., Winzeler E.A., Tevzadze G.G., Conway A.R., Hwang S.Y., Davis R.W., Esposito R.E. 2000. The core meiotic transcriptome in budding yeast. Nat Genet 26: 415-423.
18. Qiu Z.R., Schwer B., Shuman S. 2011a. Determinants of Nam8-dependent splicing of meiotic pre-mRNAs. Nucleic Acids Res 39: 3427-3445.
19. Qiu Z.R., Shuman S., Schwer B. 2011b. An essential role for trimethylguanosine RNA caps in Saccharomyces cerevisiae meiosis and their requirement for splicing of SAE3 and PCH2 meiotic pre-mRNAs. Nucleic Acids Res doi: 10.1093/nar/gkr083.
20. Rabitsch K.P., Toth A., Galova M., Schleiffer A., Schaffner G., Aigner E., Rupp C., Penkner A.M., Moreno-Borchart A.C., Primig M., et al. 2001. A screen for genes required for meiosis and spore formation based on whole-genome expression. Curr Biol 11: 1001-1009. (Pubitemid 32632714)
21. San-Segundo P.A., Roeder G.S. 1999. Pch2 links chromatin silencing to meiotic checkpoint control. Cell 97: 313-324. (Pubitemid 29214588)
22. Sickmier E.A., Frato K.E., Shen H., Paranawithana S.R., Green M.R., Kielkopf C.L. 2006. Structural basis for polypyrimidine tract recognition by the essential pre-mRNA splicing factor U2AF65. Mol Cell 23: 49-59. (Pubitemid 43963446)
23. Spingola M., Ares M. 2000. A yeast intronic splicing enhancer and Nam8p are required for Mer1p-activated splicing. Mol Cell 6: 329-338.
24. Spingola M., Armisen J., Ares M. 2004. Mer1p is a modular splicing factor whose function depends on the conserved U2 snRNP protein Snu17p. Nucleic Acids Res 32: 1242-1250. (Pubitemid 38854725)
25. Wach A., Brachat A., Pohlmann R., Philippsen P. 1994. New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae. Yeast 10: 1793-1808.