Evaluation of the anxiolytic properties of Tetrahydropalmatine, a Corydalis yanhusuo compound, in the male Sprague-Dawley rat

AANA Journal

Volumn 79, Issue SUPPL. 4, 2011, Pages

  Henkes, Herman ^a   Franz, Michael ^b   Kendall, Orin ^c   Monroe, Jacqueline ^c   Legaspi, Anna ^d   LeDoux, Joann ^e   Haese, Christopher ^e,f   Williams, Daniel ^e   McCall, Suzanne ^g   Johnson, Arthur Don ^h   Ceremuga, Thomas E ^g  

^a MADIGAN ARMY MEDICAL CENTER   (United States)

^b Irwin Army Community Hospital   (United States)

^c CARL R DARNALL ARMY MEDICAL CENTER   (United States)

^d WILLIAM BEAUMONT ARMY MEDICAL CENTER   (United States)

^e WOMACK ARMY MEDICAL CENTER   (United States)

^f LANDSTUHL REGIONAL MEDICAL CENTER   (Germany)

^g BROOKE ARMY MEDICAL CENTER   (United States)

^h BAYLOR UNIVERSITY   (United States)

Author keywords

Anxiolysis; Corydalis yanhusuo; Elevated plus maze; Sprague Dawley rat; Tetrahydropalmatine

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; FLUMAZENIL; MIDAZOLAM; TETRAHYDROPALMATINE;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY DISORDER; ARTICLE; BINDING SITE; CHINESE HERB; CONTROLLED STUDY; CORYDALIS; CORYDALIS YANHUSUO; DRUG BINDING SITE; MALE; MOTOR ACTIVITY; NONHUMAN; POST HOC ANALYSIS; RAT; SEDATION; TRANQUILIZING ACTIVITY;

ANIMALS; ANTI-ANXIETY AGENTS; CORYDALIS; DRUG THERAPY, COMBINATION; DRUGS, CHINESE HERBAL; FLUMAZENIL; GABA MODULATORS; MALE; MAZE LEARNING; MIDAZOLAM; MOTOR SKILLS; MULTIVARIATE ANALYSIS; PHYTOTHERAPY; PROSPECTIVE STUDIES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84860405444     PISSN: 00946354     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Anxiety Disorders Association of America. Statistics and Facts about Anxiety Disorders. http://www.adaa.org/AboutADAA/PressRoom/Stats&Facts.asp. Accessed December 8, 2009.
2. Levy MN, Koeppen BM, Stanton BA. Berne & Levy Principles of Physiology. 4th ed. Philadelphia, PA: Elsevier Mosby; 2006:693-698.
3. Morgan GE Jr, Mikhail MS, Murray MJ. Clinical Anesthesiology. 4th ed. New York, NY: Lange Medical Books/McGraw-Hill; 2006:187-189.
4. Barnes P, Bloom B, Nahin R. Complementary and Alternative Medicine Use Among Adults and Children: United States, 2007. National Health Statistics Reports. Number 12. December 10, 2008. http://nccam.nih.gov/news/camstats/2007/camsurvey_fs1.htm.
5. Ang-Lee MK, Moss J, Yuan CS. Herbal medicines and perioperative care. JAMA 2001;286(2):208-216.
6. Joint Commission. http://www.jointcommissioninternational.org/Medication-Safety-Articles/. Accessed December 8, 2009.
7. Sabar R, Kaye AD, Frost EA. Perioperative considerations for the patient on herbal medicines. Middle East J Anesthesiol. 2001;16(3): 287-314.
8. Wren KR, Kimbrall S, Norred CL. Complementary and alternative medicine use by surgical patients. J Perianesthesia Nurs. 2002;17(3):170-177.
9. Hu J, Xie J, Hu J, Zhang Y, Wang J, Chen R. Effect of some drugs on electroacupuncture analgesia and cytosolic free Ca2+ concentration of mice brain [in Chinese]. Zhen Ci Yan Jiu. 1994;19(1):55-58.
10. Chang CK, Lin MT. DL-Tetrahydropalmatine may act through inhibition of amygdaloid release of dopamine to inhibit an epileptic attack in rats. Neurosci Lett. 2001;307(3):163-166.
11. Chan P, Chiu WT, Chen YJ, Wu PJ, Cheng JT. Calcium influx inhibition: possible mechanism of the negative effect of tetrahydropalmatine on left ventricular pressure in isolated rat heart. Planta Med. 1999;65(4):340-342.
12. Lin MT, Chueh FY, Hsieh MT, Chen CF. Antihypertensive effects of DL-tetrahydropalmatine: an active principle isolated from Corydalis. Clin Exp Pharmacol Physiol. 1996;23(8):738-742.
13. Hong Z, Fan G, Le J, Chai Y, Yin X, Wu Y. Brain pharmacokinetics and tissue distribution of tetrahydropalmatine enantiomers in rats after oral administration of the racemate. Biopharm Drug Dispos. 2006;27(3):111-117.
14. Lin MT, Wang JJ, Young MS. The protective effect of dl-tetrahydropalmatine against the development of amygdale kindling seizures in rats. Neurosci Lett. 2002;320(3):113-116.
15. Chueh FY, Hsieh MT, Chen CF, Lin MT. DL-tetrahydropalmatineproduced hypotension and bradycardia in rats through the inhibition of central nervous dopaminergic mechanisms. Pharmacology. 1995;51(4):237-244.
16. Zhao DK, Zhao GS, Qiu PL. Effects of dl-tetrahydropalmatine on contractions of rabbit aortic strips [in Chinese]. Zhongguo Yao Xue Bao. 1988;9(2):153-155.
17. Sun F, Li DX. Effects of l-tetrahydropalmatine on isolated rabbit arterial strips [in Chinese]. Zhongguo Yao Li Xue Bao. 1989;10(1):30-33.
18. Wu L, Ling H, Jiang L, He M. Beneficial effects of the extract from Corydalis yanhusuo in rats with heart failure following myocardial infarction. J Pharm Pharmacol. 2007;59(5):695-701.
19. Xi ZX, Yang Z, Li SJ, et al. Levo-tetrahydropalmatine inhibits cocaine's rewarding effects: experiments with self-administration and brainstimulation reward in rats. Neuropharmacology.2007;53(6):771-782.
20. Chu H, Jin G, Friedman E, Zhen X. Recent development in studies of tetrahydroprotoberberines: mechanism in antinociception and drug addiction. Cell Mol Neurobiol. 2008;28(4):491-499.
21. Yang Z, Shao Y, Li S, et al. Medication of l-tetrahydropalmatine significantly ameliorates opiate craving and increases the abstinence rate in heroin users: a pilot study. Acta Pharmacol Sin. 2008;29(7):781-788.
22. Leung WC, Zheng H, Huen M, Law SL, Xue H. Anxiolytic-like action of orally administered dl-tetrahydropalmatine in elevated plus-maze. Prog Neuropsychopharmacol Biol Psychiatry. 2003;27(5):775-779.
23. Pellow S, Chopin P, File SE, Briley M. Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J Neurosci Methods. 1985;14(3):149-167.
24. Montgomery KC. The relation between fear induced by novel stimulation and exploratory behavior. J Comp Physiol Psychol. 1955;48(4):254-260.
25. Reves JG, Glass PS, Lubarsky DA, McEvoy MD. Intravenous nonopioid anesthetics. In: Miller RD, ed. Miller's Anesthesia. 6th ed. Philadelphia, PA: Elsevier Mosby; 2005:317-378.