Disulfiram stimulates dopamine release from noradrenergic terminals and potentiates cocaine-induced dopamine release in the prefrontal cortex

Psychopharmacology

Volumn 219, Issue 4, 2012, Pages 1153-1164

  Devoto, Paola ^a,b   Flore, Giovanna ^a   Saba, Pierluigi ^a   Cadeddu, Roberto ^a   Gessa, Gian Luigi ^a  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b BB Brodie Department of Neuroscience   (Italy)

Author keywords

2 Autoreceptors; Cocaine; DBH; Disulfiram; Dopamine; Microdialysis; Noradrenaline; Nucleus accumbens; Prefrontal cortex

Indexed keywords

12 ETHYLSULFONYL 5,8,8A,9,10,11,12,12A,13,13A DECAHYDRO 3 METHOXY 6H ISOQUINO[2,1 G][1,6]NAPHTHYRIDINE; ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CLONIDINE; COCAINE; DISULFIRAM; DOPAMINE; NORADRENALIN; QUINPIROLE; TETRODOTOXIN;

ALPHA ADRENERGIC RECEPTOR BLOCKING; ALPHA ADRENERGIC STIMULATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAUDATE NUCLEUS; CONTROLLED STUDY; DOPAMINE BRAIN LEVEL; DOPAMINE RELEASE; DOPAMINERGIC NERVE CELL; DRUG MECHANISM; INNERVATION; MALE; MEDIAL PREFRONTAL CORTEX; MICRODIALYSIS; NERVE ENDING; NONHUMAN; NORADRENALIN BRAIN LEVEL; NORADRENALIN RELEASE; NORADRENERGIC NERVE; NUCLEUS ACCUMBENS; OCCIPITAL CORTEX; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT;

ANIMALS; BRAIN; COCAINE; COCAINE-RELATED DISORDERS; DISULFIRAM; DOPAMINE; DOPAMINE BETA-HYDROXYLASE; ENZYME INHIBITORS; MALE; MICRODIALYSIS; NOREPINEPHRINE; PREFRONTAL CORTEX; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84860400365     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-011-2447-5     Document Type: Article

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