Extent of enthalpy-entropy compensation in protein-ligand interactions

Protein Science

Volumn 20, Issue 9, 2011, Pages 1607-1618

  Olsson, Tjelvar S G ^a,e   Ladbury, John E ^a,f   Pitt, Will R ^b,c   Williams, Mark A ^d  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UCB PHARMA   (Belgium)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d UNIVERSITY OF LONDON   (United Kingdom)

^e CAMBRIDGE CRYSTALLOGRAPHIC DATA CENTRE   (United Kingdom)

^f UNIVERSITY OF TEXAS   (United States)

Author keywords

Binding thermodynamics; Enthalpy entropy compensation; Free energy; Protein complexes; Protein ligand interactions

Indexed keywords

LIGAND; PROTEIN;

ARTICLE; CONTROLLED STUDY; ENERGY EXPENDITURE; ENTHALPY; ENTROPY; ISOTHERMAL TITRATION CALORIMETRY; LIGAND BINDING; PRIORITY JOURNAL; PROBABILITY; PROTEIN EXPRESSION; PROTEIN LIGAND INTERACTION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; QUANTITATIVE ANALYSIS; REGRESSION ANALYSIS; STATISTICAL ANALYSIS; THEORETICAL MODEL; THERMODYNAMICS;

CALORIMETRY; ENTROPY; LIGANDS; MODELS, THEORETICAL; PROTEIN BINDING; PROTEINS; THERMODYNAMICS;

EID: 84860390480     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.692     Document Type: Article

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