Synthesis, evaluation and application of polycyclic fluorescent analogues as N-methyl-d-aspartate receptor and voltage gated calcium channel ligands

European Journal of Medicinal Chemistry

Volumn 46, Issue 10, 2011, Pages 5010-5020

  Joubert, Jacques ^a,b   Dyk, Sandra Van ^a   Green, Ivan R ^b   Malan, Sarel F ^a,b  

^a NORTH WEST UNIVERSITY   (South Africa)

^b UNIVERSITY OF THE WESTERN CAPE   (South Africa)

Author keywords

Amantadine; Calcium channels; Fluorescent ligands; NMDAR; Polycyclic

Indexed keywords

2 [3 (1 ADAMANTYLAMINO)PROPYL]ISOINDOLE 1 CARBONITRILE; 3 (1 ADAMANTYLAMINO)PROPIONITRILE; 3 [4 AZA 8 OXO HEPTACYCLO [0.4.1.0 2,10 .0 3,14 .0 4,9 . 09,13 .0 12,15]TETRADECYL] 2 (METHYLAMINO)BENZOATE; 3 [4 AZA 8 OXO HEPTACYCLO[0.4.1.0 2,10 .0 3,14 .0 4,9 . 09,13 .0 12,15]TETRADECYL] 1H INDAZOLE 3 CARBOXYLATE; 3 HYDROXY 4 AZA 8 OXO HEPTACYCLO[9.4.1.0 2,10 .0 3,14 .0 4,9 .0 12,15]TETRADECANE; AMANTADINE DERIVATIVE; DIZOCILPINE; FLUORESCENT DYE; N (1 ADAMANTYL) 1,3 PROPANEDIAMINE; N (1 ADAMANTYL) 2 OXO CHROMENE 3 CARBOXAMIDE; N (1 CYANO 2H ISOINDOL 2 YL)ADAMANTAN 1 AMINE; N (2,4 DINITROPHENYL)ADAMANTAN 1 AMINE; N (ADAMANTAN 1 YL) N' (2,4 DINITROPHENYL)PROPANE 1,3 DIAMIANE; N [3 (1 ADAMANTYLAMINO)PROPYL] 1H INDAZOLE 3 CARBOXAMIDE; N [3 (1 ADAMANTYLAMINO)PROPYL] 2 METHYLAMINOBENZAMIDE; N [3 (1 ADAMANTYLAMINO)PROPYL] 5 DIMETHYLAMINONAPHTHALENE 1 SULFONAMIDE; N ADAMANTAN 1 YL 1H INDAZOLE 3 CARBOXAMIDE; N ADAMANTAN 1 YL 2 (METHYLAMINO) BENZAMIDE; N ADAMANTAN 1 YL 5 DIMETHYL AMINO 1 NAPHTHALENESULFONIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING COMPETITION; BRAIN SYNAPTOSOME; CALCIUM TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG BINDING SITE; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SYNTHESIS; FLUORESCENCE ANALYSIS; MALE; NONHUMAN; RAT; RECEPTOR AFFINITY;

AMANTADINE; ANIMALS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; FLUORESCENT DYES; LIGANDS; MALE; POLYCYCLIC HYDROCARBONS, AROMATIC; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; SYNAPTOSOMES;

EID: 84860390424     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.08.008     Document Type: Article

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