Delays in presenting for tuberculosis treatment associated with fear of learning one is HIV-positive

African Journal of AIDS Research

Volumn 10, Issue 1, 2011, Pages 25-36

  Møller, Valerie ^a   Erstad, Ida ^a   Cramm, Jane M ^b   Nieboer, Anna P ^b   Finkenflügel, Harry ^c   Radloff, Sarah ^a   Ndoro, Tinashe ^a   Kwizera, Stella A ^d  

^a RHODES UNIVERSITY   (South Africa)

^b ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^c 'S Heeren Loo   (Netherlands)

^d WALTER SISULU UNIVERSITY   (South Africa)

Author keywords

Case finding; Diagnosis and treatment; HIV status anxiety; South Africa; Stigma; Tuberculosis

Indexed keywords

ADULT; ANXIETY; DELAYED DIAGNOSIS; FEAR; FEMALE; HEALTH SURVEY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; MALE; REVIEW; SOCIAL STIGMA; SOUTH AFRICA; THERAPY DELAY; TUBERCULOSIS;

EID: 84860389930     PISSN: 16085906     EISSN: 17279445     Source Type: Journal    
DOI: 10.2989/16085906.2011.575545     Document Type: Review

References (52)

1. Barker, R. D., Millard, F. J. C., Malatsi, J., Mkoana, L., Ngoatwana, T., Agarawal, S. & De Valliere, S. (2006) Traditional healers, treatment delay, performance status and death from TB in rural South Africa. International Journal of Tuberculosis and Lung Disease 10(6), pp. 670-675. (Pubitemid 43845029)
2. Bodibe, K. (2010) 'Mass testing of learners opposed.' Health-e news agency, 22 September 2010. Online at: [Accessed 9 November 2010].
3. Bond, V. & Nyblade, L. (2006) The importance of addressing the unfolding TB-HIV stigma in high HIV-prevalence settings. Journal of Community and Applied Social Psychology 16, pp. 452-461. (Pubitemid 44846519)
4. Cambanis, A., Ramsay, A., Yassin, M. A. & Cuevas, L. E. (2007) Duration and associated factors of patient delay during tuberculosis screening in rural Cameroon. Tropical Medicine and International Health 12(11), pp. 1309-1314. (Pubitemid 350191136)
5. Chigwedere, P., Seage, G. R. 3rd, Gruskin, S., Lee, T. H. & Essex, M. (2008) Estimating the lost benefits of antiretroviral drug use in South Africa. Journal of Acquired Immune Deficiency Syndromes 49(4), pp. 410-445.
6. Corbett, E. L., Marston, B., Churchyard, G. J. & De Cock, K. M. (2006) Tuberculosis in sub-Saharan Africa: opportunities, challenges, and change in the era of antiretroviral treatment. The Lancet 367, pp. 926-937.
7. Daftary, A., Padayatchi, N. & Padilla, M. (2007) HIV testing and disclosure: a qualitative analysis of TB patients in South Africa. AIDS Care 19(4), pp. 572-577. (Pubitemid 46598748)
8. Deacon, H. (2005) Understanding HIV/AIDS Stigma. Cape Town, South Africa, HSRC Press.
9. Department of Health (DOH) [South Africa] (2000) The South African Tuberculosis Control Programme Practical Guidelines 2000. Pretoria, South Africa, DOH.
10. Dimitrova, B., Balabanova, D., Atun, R., Drobniewski, F., Levicheva, V. & Coker, R. (2006) Health service providers' perceptions of barriers to tuberculosis care in Russia. Health Policy Plan 21, pp. 265-274. (Pubitemid 43966703)
11. Dodor, E. A., Neal, K. & Kelly, S. (2008) An exploration of the causes of tuberculosis stigma in an urban district in Ghana. International Journal of Tuberculosis and Lung Disease 12(9), pp. 1048-1054.
12. Eastwood, S. V. & Hill, P. C. (2004) A gender-focused qualitative study of barriers to accessing tuberculosis treatment in The Gambia, West Africa. International Journal of Tuberculosis and Lung Disease 8(1), pp. 70-75. (Pubitemid 38120708)
13. Edington, M. E., Sekatane, C. S. & Goldstein, S. J. (2002) Patients' beliefs: Do they affect tuberculosis control? A study in a rural district of South Africa. International Journal of Tuberculosis and Lung Disease 6(12), pp. 1075-1082. (Pubitemid 36054961)
14. Erstad, I. (2007) The resurgence of tuberculosis in South Africa: an investigation into socio-economic aspects of the disease in a context of structural violence in Grahamstown, Eastern Cape. Master's thesis, Rhodes University, Department of Anthropology, Grahamstown, South Africa.
15. Farmer, P. (1997) Social inequalities and emerging infectious diseases. Emerging Infectious Diseases 2(4), pp. 259-269.
16. Gebrekristos, H. T., Lurie, M. N., Mthethwa, N. & Karim, Q. A. (2009) Disclosure of HIV status: experiences of patients enrolled in an integrated TB and HAART pilot programme in South Africa. African Journal of AIDS Research (AJAR) 8(1), pp. 1-6.
17. Granich, R. M., Gilks, C. F., Dye, C., De Cock, K. M. & Williams, B. G. (2009) Universal voluntary HIV testing with immediate antiretroviral therapy as a strategy for elimination of HIV transmission: a mathematical model. The Lancet 373, pp. 48-57.
18. Hartley, W. (2010) 'Proposed health office to ensure standards.' Business Day, 26 November 2010, p. 2.
19. Kahn, T. (2010) 'HIV-testing campaign far behind targets.' Business Day, 25 November 2010, p. 4.
20. Kalichman, S. C., Simbayi, L. C., Jooste, S., Toefy, Y., Cain, D., Cherry, C. & Kagee, A. (2005) Development of a brief scale to measure AIDS-related stigma in South Africa. AIDS and Behaviour 9(2), pp. 135-143. (Pubitemid 40884216)
21. Kanyerere, T. & Aase, A. (2005) Delays in TB hospital diagnosis - a major threat for the HIV/AIDS situation in a society: a study of TB as an opportunistic infection in southern Malawi. Norwegian Journal of Geography 59(1), pp. 55-64.
22. Karim, A. S. S., Churchyard, G. J., Karim, A. Q. & Lawn, S. D. (2009) HIV infection and tuberculosis in South Africa: an urgent need to escalate the public health response. The Lancet 374, pp. 921-933.
23. Khan, M. A., Walley, J. D., Witter, S. N., Shah, S. K. & Javeed, S. (2005) Tuberculosis patient adherence to direct observation: results of a social study in Pakistan. Health Policy Plan 20, pp. 354-365. (Pubitemid 41567094)
24. Long, N. H., Johansson, E., Lönnroth, K., Eriksson, B., Winkvist, A. & Diwan, V. K. (1999) Longer delays in tuberculosis diagnosis among women in Vietnam. International Journal of Tuberculosis and Lung Disease 3(5), pp. 388-393. (Pubitemid 29294688)
25. Lönnroth, K., Jaramillo, E., Williams, B. G., Dye, C. & Raviglione, M. (2009) Drivers of tuberculosis epidemics: the role of risk factors and social determinants. Social Science and Medicine 68(12), pp. 2240-2246.
26. Matebesi, Z. & Booysen, F. (2004) Treatment adherence among tuberculosis patients. Acta Academica 36(3), pp. 140-171.
27. Matebesi, S. Z., Meulemans, H. & Timmerman, C. (2005) Healthcare-seeking behaviour among clinic-based tuberculosis patients. Acta Academica Supplementum 2005(1), pp. 154-172.
28. Møller, V. (2010) Strengthening intergenerational solidarity in South Africa - closing the gaps in the social security system for unemployed youth: a case study of the 'perverse incentive.' Journal of Intergenerational Relationships 8(2), pp. 145-160.
29. Møller, V. & Erstad, I. (2006) 'TB is not an easy thing': Focused discussions on the stigma related to tuberculosis in the Eastern Cape in a time of HIV/AIDS. Research Report Series No. 13. Grahamstown, South Africa, Rhodes University, Institute of Social and Economic Research.
30. Møller, V. & Erstad, I. (2007) Stigma associated with tuberculosis in a time of HIV/AIDS: narratives from the Eastern Cape, South Africa. South African Review of Sociology 38(2), pp. 103-119.
31. Møller, V., Erstad, I. & Zani, D. (2010) Drinking, smoking and morality: Do 'drinkers and smokers' constitute a stigmatised stereotype or a real TB risk factor in the time of HIV/AIDS? Social Indicators Research 98(2), pp. 217-238.
32. Møller, V., Theuns, P., Erstad, I. & Bernheim, J. (2008) The best and worst times of life: narratives and assessments of subjective wellbeing by Anamnestic Comparative Self-Assessment (ACSA) in the Eastern Cape, South Africa. Social Indicators Research 89(1), pp. 1-22.
33. Ngamvithayapong, J., Winkvist, A. & Diwan, V. (2000) High AIDS awareness may cause tuberculosis patient delay: results from an HIV epidemic area, Thailand. AIDS 14, pp. 1413-1419. (Pubitemid 30459515)
34. Oeser, C. C., Escombe, A. R., Gilman, R. H., Friedland, J. S., Evans, C. A. W. & Moore, D. A. J. (2005) Does traditional medicine use hamper efforts at tuberculosis control in urban Peru? American Journal of Tropical Medicine and Hygiene 73(3), pp. 571-575. (Pubitemid 41324262)
35. Peltzer, K., Matseke, G., Mzolo, T. & Majaja, M. (2009) Determinants of knowledge of HIV status in South Africa: results from a population-based HIV survey. BMC Public Health 9, pp. 174-184.
36. Pronyk, P. M., Kahn, K. & Tollman, S. M. (2007) Using health and demographic surveillance to understand the burden of disease in populations: the case of tuberculosis in rural South Africa. Scandinavian Journal of Public Health 35(supplement 69), pp. 45-51. (Pubitemid 47241579)
37. Rajeswari, R., Muniyandi, M., Balasubramanian, R. & Narayanan, P. R. (2005) Perceptions of tuberculosis patients about their physical, mental and social wellbeing: a field report from south India. Social Science and Medicine 60, pp. 1845-1853. (Pubitemid 40431017)
38. Reniers, G. & Tesfai, R. (2009) Health services utilization during terminal illness in Addis Ababa, Ethiopia. Health Policy and Planning 24(4), pp. 312-319.
39. Rintiswati, N., Mahendradhata, Y., Suharna, S., Purwanta, Y. S., Varkevisser, C. M. & Van der Werf, M. J. (2009) Journeys to tuberculosis treatment: a qualitative study of patients, families and communities in Jogjakarta, Indonesia. BMC Public Health 9, pp. 158-167.
40. Rowe, K. A., Makhubele, B., Hargreaves, J. R., Porter, J. D., Hausler, H. P. & Pronyk, P. M. (2005) Adherence to TB preventive therapy for HIV-positive patients in rural South Africa: Implications for antiretroviral delivery in resource-poor settings? International Journal of Tuberculosis and Lung Disease 9(3), pp. 263-269. (Pubitemid 40392940)
41. Sagbakken, M., Frich, J. C. & Gunnar, A. B. (2008) Perception and management of tuberculosis symptoms in Addis Ababa, Ethiopia. Qualitative Health Research 18(10), pp. 1356-1366.
42. Shisana, O., Rehle, T., Simbayi, L. C., Zuma, K., Jooste, S., Pillay-Van Wyck, V., Mbelle, N., Van Zyl, J., Parker, W., Zungu, N. P., Pezi, S. & The SABSSM III Implementation Team (2009) South African National HIV Prevalence, Incidence, Behaviour and Communication Survey 2008: A Turning Tide among Teenagers? Cape Town, South Africa, HSRC Press.
43. Skordis-Worrall, J., Hanson, K. & Mills, A. (2010) Confusion, caring and tuberculosis diagnostic delay in Cape Town, South Africa. International Journal of Tuberculosis and Lung Disease 14(2), pp. 171-180.
44. Somma, D., Thomas, B. E., Karim, F., Kemp, J., Arias, N., Auer, C., Gosoniu, G. D., Abouihia, A. & Weiss, M. G. (2008) Gender and socio-cultural determinants of TB-related stigma in Bangladesh, India, Malawi and Colombia. International Journal of Tuberculosis and Lung Disease 12(7), pp. 856-866. (Pubitemid 351976724)
45. South African Institute of Race Relations (SAIRR) (2009) South Africa Survey 2008/2009. Johannesburg, South Africa, SAIRR.
46. South African National AIDS Council (SANAC) (2010) The National HIV Counselling and Testing Campaign Strategy. February 2010. Available at: [Accessed 9 November 2010].
47. Steinberg, J. (2008) Three-Letter Plague. Johannesburg, South Africa, Jonathan Ball Publishers.
48. Van Rensburg, D., Van Rensburg-Bonthuyzen, E. J., Heunis, C. & Meulemans, H. (2005) Tuberculosis control in South Africa: reasons for persistent failure. Acta Academica Supplementum 2005(1), pp. 1-55.
49. Woith, W. M. & Larson, J. L. (2008) Delay in seeking treatment and adherence to tuberculosis medications in Russia: a survey of patients from two clinics. International Journal of Nursing Studies 45(8), pp. 1163-1174.
50. Wood, R. (2007) Challenges of TB diagnosis and treatment in South Africa. Southern African Journal of HIV Medicine 27, pp. 44-48.
51. World Health Organization (WHO) (2010) Global Tuberculosis Control 2010. Geneva, WHO. Available at: .
52. Zhang, T., Liu, X., Bromley, H. & Tang, S. (2007) Perceptions of tuberculosis and health-seeking behaviour in rural Inner Mongolia, China. Health Policy 81(2/3), pp. 155-165. (Pubitemid 46436178)