Right Ventricular Performance in Chronic Congestive Heart Failure

Cardiology Clinics

Volumn 30, Issue 2, 2012, Pages 271-282

  Sayer, Gabriel T ^a   Semigran, Marc J ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Phosphodiesterase 5 inhibitors; Pulmonary hypertension; Right heart catheterization; Right ventricle; Right ventricular dysfunction; Right ventricular failure; Ventricular interdependence

Indexed keywords

DIGOXIN; DOBUTAMINE; DOPAMINE; ENDOTHELIN RECEPTOR ANTAGONIST; MILRINONE; OXYGEN; PROSTAGLANDIN DERIVATIVE; RIOCIGUAT; SILDENAFIL;

ANATOMY; CARDIOVASCULAR RESPONSE; CHRONIC CONGESTIVE HEART FAILURE; CHRONIC DISEASE; COMORBIDITY; CONGESTIVE HEART FAILURE; DIAGNOSTIC ACCURACY; DISEASE COURSE; DISEASE SEVERITY; FUNCTIONAL ASSESSMENT; HEART AFTERLOAD; HEART ASSIST DEVICE; HEART CATHETERIZATION; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE CONTRACTILITY; HEART PRELOAD; HEART RIGHT VENTRICLE FAILURE; HEART RIGHT VENTRICLE FUNCTION; HEART RIGHT VENTRICLE HYPERTROPHY; HEART RIGHT VENTRICLE OVERLOAD; HEART RIGHT VENTRICLE PRESSURE; HEART TRANSPLANTATION; HEART VENTRICLE CONTRACTILITY; HEART VENTRICULOGRAPHY; HEMODYNAMICS; HUMAN; HYPOXIA; MORTALITY; MYOCARDIAL DISEASE; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PULMONARY HYPERTENSION; REVIEW; TWO DIMENSIONAL ECHOCARDIOGRAPHY;

CARDIAC IMAGING TECHNIQUES; CHRONIC DISEASE; HEART CATHETERIZATION; HEART FAILURE; HUMANS; MYOCARDIAL CONTRACTION; SURVIVAL ANALYSIS; VENTRICULAR DYSFUNCTION, RIGHT; VENTRICULAR FUNCTION, LEFT; VENTRICULAR FUNCTION, RIGHT; VENTRICULAR REMODELING;

EID: 84860367200     PISSN: 07338651     EISSN: 15582264     Source Type: Journal    
DOI: 10.1016/j.ccl.2012.03.011     Document Type: Review

References (72)

1. Haddad F., Hunt S.A., Rosenthal D.N., et al. Right ventricular function in cardiovascular disease, part I. Circulation 2008, 117:1436-1448.
2. Sheehan F., Redington A. The right ventricle: anatomy, physiology and clinical imaging. Heart 2008, 94:1510-1515.
3. Dell'Italia L.J. The right ventricle: anatomy, physiology and clinical importance. Curr Probl Cardiol 1991, 16:653-720.
4. Meier G.D., Bove A.A., Santamore W.P., et al. Contractile function in canine right ventricle. Am J Physiol 1980, 239:H794-H804.
5. Shaver J.A., Nadolny R.A., O'Toole J.D., et al. Sound pressure correlates of the second heart sound. An intracardiac sound study. Circulation 1974, 49:316-325.
6. Redington A.N., Gray H.H., Hodson M.E., et al. Characterisation of the normal right ventricular pressure-volume relation by biplane angiography and simultaneous micromanometer pressure measurements. Br Heart J 1988, 59:23-30.
7. Borlaug B.A., Kass D.A. Invasive hemodynamic assessment in heart failure. Heart Fail Clin 2009, 5:217-228.
8. Guazzi M., Pepi M., Maltagliati A. How the two sides of the heart adapt to a graded impedance to venous return with head-up tilting. J Am Coll Cardiol 1995, 26(7):1732-1740.
9. Greyson C.R. Pathophysiology of right ventricular failure. Crit Care Med 2008, 36(Suppl):S57-S65.
10. Starr I., Jeffers W.A., Meade R.H. The absence of conspicuous increments of venous pressure after severe damage to the RV of the dog, with discussion of the relation between clinical congestive heart failure and heart disease. Am Heart J 1943, 26:291-301.
11. Kagan A. Dynamic responses of the right ventricle following extensive damage by cauterization. Circulation 1952, 5:816-823.
12. Damiano R.J., La Follette P., Cox J.L., et al. Significant left ventricular contribution to right ventricular systolic function. Am J Physiol 1991, 261:H1514-H1524.
13. Brooks H., Kirk E.S., Vokonas P.S., et al. Performance of the right ventricle under stress: relation to right coronary flow. J Clin Invest 1971, 50:2176-2183.
14. Webb G., Gatzoulis M.A. Atrial septal defects in the adult. Circulation 2006, 114:1645-1653.
15. Szabo G., Soos P., Bahrle S., et al. Adaptation of the right ventricle to an increased afterload in the chronically volume overloaded heart. Ann Thorac Surg 2006, 82:989-995.
16. Abel F.L., Waldhausen J.A. Effects of alterations in pulmonary vascular resistance on right ventricular function. J Thorac Cardiovasc Surg 1967, 54:886-894.
17. Guyton A.C., Lindsey A.W., Gilluly J.J. The limits of right ventricular compensation following acute increase in pulmonary circulatory resistance. Circ Res 1954, 2:326-332.
18. Haddad F., Doyle R., Murphy D.J., et al. Right ventricular function in cardiovascular disease, Part II. Circulation 2008, 117:1717-1731.
19. Bogaard H.J., Abe K., Noordegraaf A.V., et al. The right ventricle under pressure: cellular and molecular mechanisms of right-heart failure in pulmonary hypertension. Chest 2009, 135:794-804.
20. Lowes B.D., Minobe W., Abraham W.T., et al. Changes in gene expression in the intact human heart: downregulation of alpha-myosin heavy chain in hypertrophied, failing ventricular myocardium. J Clin Invest 1997, 100(9):2315-2324.
21. Bishop J.E., Rhodes S., Laurent G.J., et al. Increased collagen synthesis and decreased collagen degradation in right ventricular hypertrophy induced by pressure overload. Cardiovasc Res 1994, 28:1581-1585.
22. Nootens M., Kaufmann E., Rector T., et al. Neurohormonal activation in patients with right ventricular failure from pulmonary hypertension: relation to hemodynamic variables and endothelin levels. J Am Coll Cardiol 1995, 26:1581-1585.
23. Rouleau J.L., Kapuku G., Pelletier S., et al. Cardioprotective effects of ramipril and losartan in right ventricular pressure overload in the rabbit: importance of kinins and influence on angiotensin II type I receptor signaling pathway. Circulation 2001, 104:939-944.
24. Mancini D.M., Eisen H., Kussmaul W., et al. Value of peak exercise oxygen consumption for optimal timing of cardiac transplantation in ambulatory patients with heart failure. Circulation 1991, 83:778-786.
25. Di Salvo T.G., Mathier M., Semigran M.J., et al. Preserved right ventricular ejection fraction predicts exercise capacity and survival in advanced heart failure. J Am Coll Cardiol 1995, 25:1143-1153.
26. Baker B., Wilen M., Boyd C., et al. Relation of right ventricular ejection fraction to exercise capacity in chronic congestive heart failure. Am J Cardiol 1985, 55:1037-1042.
27. Lewis G.D., Shah R.V., Pappagianopolas P.P., et al. Determinants of ventilator efficiency in heart failure: the role of right ventricular performance and pulmonary vascular tone. Circ Heart Fail 2008, 1:227-233.
28. Rubis P., Podolec P., Kopec G., et al. The dynamic assessment of right-ventricular function and its relation to exercise capacity in heart failure. Eur J Heart Fail 2010, 12:260-267.
29. Clark A.L., Swan J.W., Laney R., et al. The role of right and left ventricular function in the ventilator response to exercise in chronic heart failure. Circulation 1994, 89:2062-2069.
30. Mullens W., Abrahams Z., Tang W.H., et al. Importance of venous congestion for worsening of renal function in advanced decompensated heart failure. J Am Coll Cardiol 2009, 53(7):589-596.
31. Testani J.M., Khera A.V., St John Sutton M.G., et al. Effect of right ventricular function and venous congestion on cardiorenal interactions during the treatment of decompensated heart failure. Am J Cardiol 2010, 105(4):511-516.
32. Juilliere Y., Barbier G., Feldmann L., et al. Additional predictive value of both left and right ventricular ejection fractions on long-term survival in idiopathic dilated cardiomyopathy. Eur Heart J 1997, 18:276-280.
33. Polak J.F., Holman B.L., Wynne J., et al. Right ventricular ejection fraction: an indicator of increased mortality in patients with congestive heart failure associated with coronary artery disease. J Am Coll Cardiol 1983, 2:217-224.
34. de Groote P., Millaire A., Foucher-Hossein C., et al. Right ventricular ejection fraction is an independent predictor of survival in patients with moderate heart failure. J Am Coll Cardiol 1998, 32:948-954.
35. Ghio S., Gavazzi A., Campana C., et al. Independent and additive prognostic value of right ventricular systolic function and PA pressure in patients with chronic heart failure. J Am Coll Cardiol 2001, 37:183-188.
36. Gavazzi A., Berzuini C., Campana C., et al. Value of right ventricular ejection fraction in predicting short-term prognosis of patients with severe chronic heart failure. J Heart Lung Transplant 1997, 16:774-785.
37. Meyer P., Filippatos G.S., Ahmed M.I., et al. Effects of right ventricular ejection fraction on outcomes in chronic systolic heart failure. Circulation 2010, 121:252-258.
38. Bursi F., McNallan S.M., Redfield M.M., et al. Pulmonary pressures and death in heart failure. J Am Coll Cardiol 2012, 59:222-231.
39. Sanz J., Fernandez-Friera L., Moral S. Imaging techniques and the evaluation of the right heart and the pulmonary circulation. Rev Esp Cardiol 2010, 63(2):209-223.
40. Lang R.M., Bierig M., Devereux R.B., et al. Recommendations for chamber quantification: a report from the American Society of Echocardiography's Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. J Am Soc Echocardiogr 2005, 18:1440-1463.
41. Jenkins C., Chan J., Bricknell K., et al. Reproducibility of right ventricular volumes and ejection fraction using real-time three-dimensional echocardiography: comparison with cardiac MRI. Chest 2007, 131(6):1844-1851.
42. Kjaergaard J., Petersen C.L., Kjaer A., et al. Evaluation of right ventricular volume and function by 2D and 3D echocardiography compared to MRI. Eur J Echocardiogr 2006, 7:430-438.
43. Van der Zwaan H., Helbing W., McGhie J., et al. Clinical value of real-time three-dimensional echocardiography for right ventricular quantification in congenital heart disease: validation with cardiac magnetic resonance imaging. J Am Soc Echocardiogr 2010, 23:134-140.
44. Anavekar N.S., Gerson D., Skali H., et al. Two-dimensional assessment of right ventricular function: an echocardiographic-MRI correlative study. Echocardiography 2007, 24(5):452-456.
45. Anavekar N.S., Skali H., Bourgoun M., et al. Usefulness of right ventricular fractional area change to predict death, heart failure, and stroke following myocardial infarction (from the VALIANT ECHO Study). Am J Cardiol 2008, 101(5):607-612.
46. Zornoff L.A., Skali H., Pfeffer M.A., et al. Right ventricular dysfunction and risk of heart failure and mortality after myocardial infarction. J Am Coll Cardiol 2002, 39(9):1450-1455.
47. Forfia P.R., Fisher M.R., Mathai S.C., et al. Tricuspid annular displacement predicts survival in pulmonary hypertension. Am J Respir Crit Care Med 2006, 174:1034-1041.
48. Engstrom A.E., Vis M.M., Bouma B.J., et al. Right ventricular dysfunction is an independent predictor for mortality in ST-elevation myocardial infarction patients presenting with cardiogenic shock on admission. Eur J Heart Fail 2010, 12(3):276-282.
49. Kjaergaard J., Akkan D., Iversen K.K., et al. Right ventricular dysfunction as an independent predictor of short- and long-term mortality in patients with heart failure. Eur J Heart Fail 2007, 9(6-7):610-616.
50. Vogel M., Derrick G., White P.A., et al. Validation of myocardial acceleration during isovolumic contraction as a novel noninvasive index of right ventricular contractility: comparison with ventricular pressure-volume relations in an animal model. Circulation 2002, 105:1693-1699.
51. Tei C., Dujardin K.S., Hodge D.O., et al. Doppler echocardiographic index for assessment of global right ventricular function. J Am Soc Echocardiogr 1996, 9:838-847.
52. Pavlicek M., Wahl A., Rutz T., et al. Right ventricular systolic function assessment: rank of echocardiographic methods vs. cardiac magnetic resonance imaging. Eur J Echocardiogr 2011, 12(11):871-880.
53. Yeo T.C., Dujardin K.S., Tei C. Value of a Doppler-derived index combining systolic and diastolic time intervals in predicting outcome in primary pulmonary hypertension. Am J Cardiol 1998, 81:1157-1161.
54. Harjai K.L., Scott L., Vivekananthan K., et al. The Tei index: a new prognostic index for patients with symptomatic heart failure. J Am Soc Echocardiogr 2002, 15(9):864-868.
55. Bourantas C.V., Loh H.P., Bragadeesh T., et al. Relationship between right ventricular volumes measured by cardiac magnetic resonance imaging and prognosis in patients with chronic heart failure. Eur J Heart Fail 2011, 13(1):52-60.
56. van Wolferen S.A., Marcus J.T., Boonstra A., et al. Prognostic value of right ventricular mass, volume, and function in idiopathic pulmonary arterial hypertension. Eur Heart J 2007, 28(10):1250-1257.
57. Knauth A.L., Gauvreau K., Powell A.J., et al. Ventricular size and function assessed by cardiac MRI predict major adverse clinical outcomes late after tetralogy of Fallot repair. Heart 2008, 94(2):211-216.
58. Wilkoff B.L., Bello D., Taborsky M., et al. Magnetic resonance imaging in patients with a pacemaker system designed for the magnetic resonance environment. Heart Rhythm 2011, 8:65-73.
59. Chatterjee N.A., Lewis G.D. What is the prognostic significance of pulmonary hypertension in heart failure?. Circ Heart Fail 2011, 4(5):541-545.
60. Costard-Jackle A., Fowler M.B. Influence of preoperative pulmonary artery pressure on mortality after heart transplantation: testing of potential reversibility of pulmonary hypertension with nitroprusside is useful in defining a high risk group. J Am Coll Cardiol 1992, 19:48-54.
61. Champion H.C., Michelakis E.F., Hassoun P.M. Comprehensive invasive and noninvasive approach to the right ventricle - Pulmonary Circulation Unit. Circulation 2009, 120:992-1007.
62. Barst R.J., Gibbs J.S., Ghofrani H.A., et al. Updated evidence-based treatment algorithm in pulmonary arterial hypertension. J Am Coll Cardiol 2009, 54(Suppl 1):S78-S84.
63. Humbert M., Sitbon O., Simonneau G. Treatment of pulmonary arterial hypertension. N Engl J Med 2004, 351(14):1425-1436.
64. Lewis G.D., Lachmann J., Camuso J., et al. Sildenafil improves exercise hemodynamics and oxygen uptake in patients with systolic heart failure. Circulation 2007, 115(1):59-66.
65. Guazzi M., Samaja M., Arena R., et al. Long-term use of sildenafil in the therapeutic management of heart failure. J Am Coll Cardiol 2007, 50:2136-2144.
66. Lewis G.D., Shah R., Shahzad K. Sildenafil improves exercise capacity and quality of life in patients with systolic heart failure and secondary pulmonary hypertension. Circulation 2007, 116(14):1555-1562.
67. Guazzi M., Vicenzi M., Arena R., et al. Pulmonary hypertension in heart failure with preserved ejection fraction: a target of phosphodiesterase-5 inhibition in a 1-year study. Circulation 2011, 124(2):164-174.
68. Califf R.M., Adams K.F., McKenna W.J., et al. A randomized controlled trial of epoprostenol therapy for severe congestive heart failure: The Flolan International Randomized Survival Trial (FIRST). Am Heart J 1997, 134(1):44-54.
69. Kalta P.R., Moon J.C., Coats A.J. Do the results of the ENABLE (Endothelin Antagonist Bosentan for Lowering Cardiac Events in Heart Failure) study spell the end for non-selective endothelin antagonism in heart failure?. Int J Cardiol 2002, 85(2-3):195-197.
70. Kaluski E., Cotter G., Leitman M., et al. Clinical and hemodynamic effects of bosentan dose optimization in symptomatic heart failure patients with severe systolic dysfunction, associated with secondary pulmonary hypertension - a multi-center randomized study. Cardiology 2008, 109:273-280.
71. Rich S., Seidlitz M., Dodin E., et al. The short-term effects of digoxin in patients with right ventricular dysfunction from pulmonary hypertension. Chest 1998, 114(3):787-792.
72. Nagendran J., Archer S.L., Soliman D., et al. Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility. Circulation 2007, 116:238-248.