Autotaxin and its product lysophosphatidic acid suppress brown adipose differentiation and promote diet-induced obesity in mice

Molecular Endocrinology

Volumn 26, Issue 5, 2012, Pages 786-797

  Federico, Lorenzo ^a   Ren, Hongmei ^a   Mueller, Paul A ^a   Wu, Tao ^a   Liu, Shuying ^d   Popovic, Jelena ^a   Blalock, Eric M ^a   Sunkara, Manjula ^a   Ovaa, Huib ^c   Albers, Harald M ^c   Mills, Gordon B ^d   Morris, Andrew J ^a   Smyth, Susan S ^a,b  

^a UNIVERSITY OF KENTUCKY   (United States)

^b LEXINGTON VA MEDICAL CENTER   (United States)

^c NETHERLANDS CANCER INSTITUTE   (Netherlands)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; AUTOTAXIN; COMPLEMENTARY DNA; DEXAMETHASONE; INSULIN; ISOBUTYLMETHYLXANTHINE; LYSOPHOSPHATIDIC ACID; MESSENGER RNA; RECOMBINANT ENZYME; RETINOIC ACID; ROSIGLITAZONE; UNCOUPLING PROTEIN 1;

ADIPOCYTE; ADIPOGENESIS; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BODY FAT; BODY TEMPERATURE; BROWN ADIPOSE TISSUE; CELL CULTURE; CELL DIFFERENTIATION; COLD TOLERANCE; CONTROLLED STUDY; DIET; DUAL ENERGY X RAY ABSORPTIOMETRY; FIBROBLAST CULTURE; GENE EXPRESSION; LIPID DIET; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROADIPOCYTE; TRANSGENIC MOUSE; WHITE ADIPOSE TISSUE; WILD TYPE;

ADIPOGENESIS; ADIPOKINES; ADIPOSE TISSUE, BROWN; ANIMALS; CELLS, CULTURED; CYTOKINES; DIET, HIGH-FAT; EMBRYO, MAMMALIAN; ENZYME INHIBITORS; FIBROBLASTS; GENE EXPRESSION REGULATION; ION CHANNELS; LYSOPHOSPHOLIPIDS; MALE; MICE; MICE, TRANSGENIC; MITOCHONDRIAL PROTEINS; OBESITY; PHOSPHORIC DIESTER HYDROLASES; RANDOM ALLOCATION; RECOMBINANT PROTEINS; RNA, MESSENGER; SUBCUTANEOUS FAT;

MUS; MUS MUSCULUS;

EID: 84860347166     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2011-1229     Document Type: Article

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