A polymorphism at the miR-502 binding site in the 3'-untranslated region of the histone methyltransferase SET8 is associated with hepatocellular carcinoma outcome

International Journal of Cancer

Volumn 131, Issue 6, 2012, Pages 1318-1322

  Guo, Zhanjun ^a   Wu, Chensi ^a   Wang, Xiaoling ^a   Wang, Cuiju ^a   Zhang, Ruixing ^a   Shan, Baoen ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

HCC; microRNA; outcome; polymorphism; SET8

Indexed keywords

CYTOSINE; HISTONE METHYLTRANSFERASE; METHYLTRANSFERASE; MICRORNA; MICRORNA 502; PROTEIN SET8; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ADULT; ARTICLE; BINDING AFFINITY; BINDING SITE; CANCER GENETICS; CANCER PATIENT; CANCER SURVIVAL; CHINESE; CONTROLLED STUDY; FEMALE; GENE; GENE EXPRESSION; GENETIC ASSOCIATION; GENOTYPE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RNA BINDING; SET8 GENE; SINGLE NUCLEOTIDE POLYMORPHISM; SURVIVAL TIME;

3' UNTRANSLATED REGIONS; ADULT; AGED; BINDING SITES; CARCINOMA, HEPATOCELLULAR; FEMALE; GENOTYPE; HISTONE-LYSINE N-METHYLTRANSFERASE; HUMANS; LIVER NEOPLASMS; MALE; MICRORNAS; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PROPORTIONAL HAZARDS MODELS;

EID: 84860346238     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.27352     Document Type: Article

References (29)

1. Gomaa AI, Khan SA, Toledano MB, Waked I, Taylor-Robinson SD,. Hepatocellular carcinoma: epidemiology, risk factors and pathogenesis. World J Gastroenterol 2008; 14: 4300-8.
2. Caldwell S, Park SH,. The epidemiology of hepatocellular cancer: from the perspectives of public health problem to tumor biology. J Gastroenterol 2009; 44: 96-101.
3. Lu FM, Zhuang H,. Management of hepatitis B in China. Chin Med J 2009; 122: 3-4.
4. Lu L, Wang X,. Drug addiction in China. Ann NY Acad Sci 2008; 1141: 304-17.
5. Maki A, Kono H, Gupta M, Asakawa M, Suzuki T, Matsuda M, Fujii H, Rusyn I,. Predictive power of biomarkers of oxidative stress and inflammation in patients with hepatitis C virus-associated hepatocellular carcinoma. Anal Surg Oncol 2007; 14: 1182-90.
6. Okada S, Shimada K, Yamamoto J, Takayama T, Kosuge T, Yamasaki S, Sakamoto M, Hirohashi S,. Predictive factors for postoperative recurrence of hepatocellular carcinoma. Gastroenterology 1994; 106: 1618-24.
7. Minagawa M, Makuuchi M, Takayama T, Kokudo N,. Selection criteria for repeat hepatectomy in patients with recurrent hepatocellular carcinoma. Ann Surg 2003; 238: 703-10.
8. Wang C, Zhang F, Fan H, Peng L, Zhang R, Liu S, Guo Z,. Sequence polymorphisms of mitochondrial D-loop and hepatocellular carcinoma outcome. Biochem Biophys Res Commun 2011; 406: 493-6.
9. Bartel DP,. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116: 281-97.
10. Ambros V,. The functions of animal microRNAs. Nature 2004; 431: 350-5.
11. Lewis BP, Burge CB, Bartel DP,. Conserved seed pairing, often flanked by adenosines, indicated that thousands of human genes are microRNA target. Cell 2005; 120: 15-20.
12. Zeng Y, Yi R, Cullen BR,. MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms. Proc Natl Acad Sci USA 2003; 100: 9779-84.
13. Zeng Y, Wagner EJ, Cullen BR,. Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells. Mol Cell 2002; 9: 1327-33.
14. Chin LJ, Ratner E, Leng S, Zhai R, Nallur S, Babar I, Muller RU, Straka E, Su L, Burki EA, Crowell RE, Patel R, et al. A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. Cancer Res 2008; 68: 8535-40.
15. Brendle A, Lei H, Brandt A, Johansson R, Enquist K, Henriksson R, Hemminki K, Lenner P, Försti A,. Polymorphisms in predicted microRNA-binding sites in integrin genes and breast cancer: ITGB4 as prognostic marker. Carcinogenesis 2008; 29: 1394-9.
16. Yu Z, Li Z, Jolicoeur N, Zhang L, Fortin Y, Wang E, Wu M, Shen S-H,. Aberrant allele frequencies of the SNPs located in microRNA target sites are potentially associated with human cancers. Nucleic Acids Res 2007; 35: 4535-41.
17. Landi D, Gemignani F, Naccarati A, Pardini B, Vodicka P, Vodickova L, Novotny J, Forsti A, Hemminki K, Canzian F, Landi S,. Polymorphisms within micro-RNA-binding sites and risk of sporadic colorectal cancer. Carcinogenesis 2008; 29: 579-84.
18. Saunders MA, Liang H, Li W-H,. Human polymorphism at microRNA and microRNA target sites. Proc Natl Acad Sci USA 2007; 9: 3300-5.
19. Gao Y, He Y, Ding J, Wu K, Hu B, Liu Y, Wu Y, Guo B, Shen Y, Landi D, Landi S, Zhou Y, Liu H,. An insertion/deletion polymorphism at miRNA-122-binding site in the interleukin-1alpha 3' untranslated region confers risk for hepatocellular carcinoma. Carcinogenesis 2009; 30: 2064-9.
20. Fang J, Feng Q, Ketel CS, Wang H, Cao R, Xia L, Erdjument-Bromage H, Tempst P, Simon JA, Zhang Y,. Purification and functional characterization of SET8, a nucleosomal histone H4-lysine 20-specific methyltransferase. Curr Biol 2002; 12: 1086-99.
21. Nishioka K, Rice JC, Sarma K, Erdjument-Bromage H, Werner J, Wang Y, Chuikov S, Valenzuela P, Tempst P, Steward R, Lis JT, Allis CD, et al. PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin. Mol Cell 2002; 9: 1201-13.
22. Wu S, Wang W, Kong X, Congdon LM, Yokomori K, Kirschner MW, Rice JC,. Dynamic regulation of the PR-Set7 histone methyltransferase is required for normal cell cycle progression. Genes Dev 2010; 24: 2531-42.
23. Song F, Zheng H, Liu B, Wei S, Dai H, Zhang L, Calin GA, Hao X, Wei Q, Zhang W, Chen K,. An miR-502-binding site single-nucleotide polymorphism in the 3'-untranslated region of the SET8 gene is associated with early age of breast cancer onset. Clin Cancer Res 2009; 19: 6292-300.
24. Singh M, Zaino RJ, Filiaci VJ, Leslie KK,. Relationship of estrogen and progesterone receptors to clinical outcome in metastatic endometrial carcinoma: A Gynecologic Oncology Group Study. Gynecol Oncol 2007; 106: 325-33.
25. Merritt WM, Lin YG, Han LY, Kamat AA, Spannuth WA, Schmandt R, Urbauer D, Pennacchio LA, Cheng JF, Nick AM, Deavers MT, Mourad-Zeidan A, et al. Dicer, Drosha, and outcomes in patients with ovarian cancer. N Engl J Med 2008; 359: 2641-50.
26. Horikawa Y, Wood CG, Yang H, Zhao H, Ye Y, Gu J, Lin J, Habuchi T, Wu X,. Single nucleotide polymorphisms of microRNA machinery genes modify the risk of renal cell carcinoma. Clin Cancer Res 2008; 14: 7956-62.
27. Hu Z, Chen J, Tian T, Zhou X, Gu H, Xu L, Zeng Y, Miao R, Jin G, Ma H, Chen Y, Shen H,. Genetic variants of miRNA sequences and non-small cell lung cancer survival. J Clin Invest 2008; 118: 2600-8.
28. Shi X, Kachirskaia I, Yamaguchi H, West LE, Wen H, Wang EW, Dutta S, Appella E, Gozani O,. Modulation of p53 function by SET8-mediated methylation at lysine 382. Mol Cell 2007; 27: 636-46.
29. Iorio MV, Ferracin M, Liu CG, Veronese A, Spizzo R, Sabbioni S, Magri E, Pedriali M, Fabbri M, Campiglio M, Ménard S, Palazzo JP, et al. MicroRNA gene expression deregulation in human breast cancer. Cancer Res 2005; 65: 7065-70.