Genetic polymorphisms located in TGFB1, AGTR1, and VEGFA genes are associated to chronic renal allograft dysfunction

Cytokine

Volumn 58, Issue 3, 2012, Pages 321-326

  Jiménez Sousa, María A ^a   Fernández Rodríguez, Amanda ^a   Heredia, María ^b   Tamayo, Eduardo ^b   Guzmán Fulgencio, María ^a   Lajo, Carmen ^b   López, Elisabeth ^b   Gómez Herreras, José I ^b   Bustamante, Jesús ^b   Bermejo Martín, Jesús F ^b   Resino, Salvador ^a  

^a INSTITUTO DE SALUD CARLOS III   (Spain)

^b HOSPITAL CLÍNICO UNIVERSITARIO DE VALLADOLID   (Spain)

Author keywords

Allograft rejection; Biomarkers; Grow factors; Kidney transplant; SNPs

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; HLA ANTIGEN; TRANSFORMING GROWTH FACTOR BETA1; VASCULOTROPIN A;

ADULT; AGTR1 GENE; ARTICLE; CHRONIC ALLOGRAFT NEPHROPATHY; COLD ISCHEMIA; CONTROLLED STUDY; FEMALE; GENE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENOTYPE; GRAFT RECIPIENT; HLA TYPING; HUMAN; IMMUNE RESPONSE; IMMUNOPATHOGENESIS; INFLAMMATION; KIDNEY DONOR; KIDNEY TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SINGLE NUCLEOTIDE POLYMORPHISM; TGFB1 GENE; VEGFA GENE;

ADULT; AGED; FEMALE; GRAFT REJECTION; HUMANS; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTOR, ANGIOTENSIN, TYPE 1; RETROSPECTIVE STUDIES; TRANSFORMING GROWTH FACTOR BETA1; TRANSPLANTATION, HOMOLOGOUS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84860345389     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2012.02.017     Document Type: Article

References (32)

1. Levey A.S., Atkins R., Coresh J., Cohen E.P., Collins A.J., Eckardt K.U., et al. Chronic kidney disease as a global public health problem: approaches and initiatives - a position statement from kidney disease improving global outcomes. Kidney Int 2007, 72:247-259.
2. Howard K., Salkeld G., White S., McDonald S., Chadban S., Craig J.C., et al. The cost-effectiveness of increasing kidney transplantation and home-based dialysis. Nephrology (Carlton) 2009, 14:123-132.
3. Campistol J.M., Boletis I.N., Dantal J., de Fijter J.W., Hertig A., Neumayer H.H., et al. Chronic allograft nephropathy - a clinical syndrome: early detection and the potential role of proliferation signal inhibitors. Clin Transplant 2009, 23:769-777.
4. Joosten S.A., Sijpkens Y.W., van Kooten C., Paul L.C. Chronic renal allograft rejection: pathophysiologic considerations. Kidney Int 2005, 68:1-13.
5. Sellares J., de Freitas D.G., Mengel M., Sis B., Hidalgo L.G., Matas A.J., et al. Inflammation lesions in kidney transplant biopsies: association with survival is due to the underlying diseases. Am J Transplant 2011, 11:489-499.
6. Racusen L.C., Regele H. The pathology of chronic allograft dysfunction. Kidney Int 2010, 78(Suppl. 119):S27-S32.
7. Perco P., Oberbauer R. Integrative analysis of - omics data and histologic scoring in renal disease and transplantation: renal histogenomics. Semin Nephrol 2010, 30:520-530.
8. Grafals M., Kamal L., Chung D., Abdi R. Gene polymorphisms in renal transplantation. Semin Nephrol 2010, 30:418-425.
9. Kocierz M., Siekiera U., Kolonko A., Karkoszka H., Chudek J., Cierpka L., et al. 174G/C interleukin-6 gene polymorphism and the risk of transplanted kidney failure or graft loss during a 5-year follow-up period. Tissue Antigens 2011, 77:283-290.
10. Kasiske B.L., Andany M.A., Danielson B. A thirty percent chronic decline in inverse serum creatinine is an excellent predictor of late renal allograft failure. Am J Kid Dis 2002, 39:762-768.
11. Ribases M., Ramos-Quiroga J.A., Sanchez-Mora C., Bosch R., Richarte V., Palomar G., et al. Contribution of LPHN3 to the genetic susceptibility to ADHD in adulthood: a replication study. Genes Brain Behav 2010, 10:149-157.
12. Sole X., Guino E., Valls J., Iniesta R., Moreno V. SNPStats: a web tool for the analysis of association studies. Bioinformatics 2006, 22:1928-1929.
13. Rao M., Guo D., Jaber B.L., Tighiouart H., Pereira B.J., Balakrishnan V.S. Transforming growth factor-beta 1 gene polymorphisms and cardiovascular disease in hemodialysis patients. Kidney Int 2004, 66:419-427.
14. Wang Z., Burge C.B. Splicing regulation: from a parts list of regulatory elements to an integrated splicing code. RNA 2008, 14:802-813.
15. Poole K.L., Gibbs P.J., Evans P.R., Sadek S.A., Howell W.M. Influence of patient and donor cytokine genotypes on renal allograft rejection: evidence from a single centre study. Transpl Immunol 2001, 8:259-265.
16. Adamopoulos S., Kolokathis F., Gkouziouta A., Georgiadou P., Chaidaroglou A., Karavolias G.K., et al. Cytokine gene polymorphisms are associated with markers of disease severity and prognosis in patients with idiopathic dilated cardiomyopathy. Cytokine 2011, 54:68-73.
17. Xu H.Y., Hou X.W., Wang L.F., Wang N.F., Xu J. Association between transforming growth factor beta1 polymorphisms and left ventricle hypertrophy in essential hypertensive subjects. Mol Cell Biochem 2010, 335:13-17.
18. Densem C.G., Hutchinson I.V., Yonan N., Brooks N.H. Donor and recipient-transforming growth factor-beta 1 polymorphism and cardiac transplant-related coronary artery disease. Transpl Immunol 2004, 13:211-217.
19. Valladares-Salgado A., Angeles-Martinez J., Rosas M., Garcia-Mena J., Utrera-Barillas D., Gomez-Diaz R., et al. Association of polymorphisms within the transforming growth factor-beta1 gene with diabetic nephropathy and serum cholesterol and triglyceride concentrations. Nephrology (Carlton) 2010, 15:644-648.
20. Chen Y., Dawes P.T., Packham J.C., Mattey D.L. Interaction between smoking and polymorphism in the promoter region of the VEGFA gene is associated with ischemic heart disease and myocardial infarction in rheumatoid arthritis. J Rheumatol 2011, 38:802-809.
21. Heldal K., Hartmann A., Leivestad T., Foss A., Midtvedt K. Risk variables associated with the outcome of kidney recipients >70years of age in the new millennium. Nephrol Dial Transplant 2011, 26:2706-2711.
22. Howell W.M., Ali S., Rose-Zerilli M.J., Ye S. VEGF polymorphisms and severity of atherosclerosis. J Med Genet 2005, 42:485-490.
23. Lemos F.B., Mol W.M., Roodnat J.I., Uitterlinden A., Ijzermans J.N., Weimar W., et al. The beneficial effects of recipient-derived vascular endothelial growth factor on graft survival after kidney transplantation. Transplantation 2005, 79:1221-1225.
24. Szeto C.C., Chow K.M., Poon P., Szeto C.Y., Wong T.Y., Li P.K. Genetic polymorphism of VEGF: impact on longitudinal change of peritoneal transport and survival of peritoneal dialysis patients. Kidney Int 2004, 65:1947-1955.
25. Yosypiv I.V. Renin-angiotensin system in ureteric bud branching morphogenesis: insights into the mechanisms. Pediatr Nephrol 2011, 26:1499-1512.
26. Conne B., Stutz A., Vassalli J.D. The 3' untranslated region of messenger RNA: a molecular 'hotspot' for pathology?. Nat Med 2000, 6:637-641.
27. Sethupathy P., Borel C., Gagnebin M., Grant G.R., Deutsch S., Elton T.S., et al. Human microRNA-155 on chromosome 21 differentially interacts with its polymorphic target in the AGTR1 3' untranslated region: a mechanism for functional single-nucleotide polymorphisms related to phenotypes. Am J Hum Genet 2007, 81:405-413.
28. Kocierz M., Kujawa-Szewieczek A., Kolonko A., Chudek J., Wiecek A. The influence of selected cytokine gene polymorphisms on the occurrence of acute and chronic rejection and on kidney graft survival. Postepy Hig Med Dosw (Online) 2009, 63:613-626.
29. Lee Y.T., Chiu H.C., Huang C.T., Su H.M., Wang C.L., Lin T.H., et al. The A1166C polymorphism of angiotensin II type 1 receptor as a predictor of renal function decline over 4years follow-up in an apparently healthy Chinese population. Clin Nephrol 2009, 72:457-467.
30. Chen S., Lee J.S., Iglesias-de la Cruz M.C., Wang A., Izquierdo-Lahuerta A., Gandhi N.K., et al. Angiotensin II stimulates alpha3(IV) collagen production in mouse podocytes via TGF-beta and VEGF signalling: implications for diabetic glomerulopathy. Nephrol Dial Transplant 2005, 20:1320-1328.
31. Perneger T.V. What's wrong with Bonferroni adjustments. BMJ 1998, 316:1236-1238.
32. Burton P.R., Tobin M.D., Hopper J.L. Key concepts in genetic epidemiology. Lancet 2005, 366:941-951.