Use of a third-generation perfluorocarbon for preservation of rat DCD liver grafts

Journal of Surgical Research

Volumn 175, Issue 1, 2012, Pages 131-137

  Bezinover, Dmitri ^a   Ramamoorthy, Saravanan ^a   Uemura, Todahiro ^a   Kadry, Zakiyah ^a   McQuillan, Patrick M ^a   Mets, Berend ^a   Falcucci, Octavio ^a   Rannels, Sharon ^a   Ruiz Velasco, Victor ^a   Spiess, Bruce ^b   Liang, John ^a   Mani, Haresh ^a   Lou, Xi ^a   Janicki, Piotr K ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

apoptosis; caspase 3; marginal grafts; perfluorocarbon; warm ischemic time

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CASPASE 3; CASPASE 3 ANTIBODY; EOSIN; FLUOROCARBON; HEMATOXYLIN; UNCLASSIFIED DRUG; UNIVERSITY OF WISCONSIN SOLUTION;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN ANTIBODY REACTION; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CADAVER DONOR; CARDIOPULMONARY ARREST; CELL CONGESTION; CELL COUNT; CELL DEATH; CELL VACUOLE; CONTROLLED STUDY; DONATION AFTER CARDIAC DEATH; GRAFT PRESERVATION; IMMUNOHISTOCHEMISTRY; LIVER GRAFT; LIVER INJURY; LIVER ISCHEMIA; LIVER TRANSPLANTATION; NONHUMAN; PRIORITY JOURNAL; RAT; STAINING;

ADENOSINE; ALLOPURINOL; ANIMALS; DEATH; FLUOROCARBONS; GLUTATHIONE; INSULIN; LIVER; ORGAN PRESERVATION; ORGAN PRESERVATION SOLUTIONS; PERFUSION; RAFFINOSE; RATS; TRANSPLANTS;

EID: 84860339215     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2011.02.046     Document Type: Article

References (32)

1. P. Muiesan, R. Girlanda, and W. Jassem Single-center experience with liver transplantation from controlled non-heart-beating donors: A viable source of grafts Ann Surg 242 2005 732
2. B.D. Spiess Perfluorocarbon emulsions as a promising technology: A review of tissue and vascular gas dynamics J Appl Physiol 106 2009 1444
3. L.C. Clark, F. Becattini, and S. Kaplan The physiological effects of artificial blood made from inert organic solvents Ala J Med Sci 9 1972 16
4. Leone BJ. Artificial blood: What is it? Will I use it? Jacksonville Medicine [serial on the Internet] Available at: http://dcmsonline.org/jax- medicine/1998journals/december98/artificialblood.htm. Accessed November 9, 2009.
5. N. Kamada, R.Y. Caln, and D.G.D. Wight Ortotopic rat liver transplantation after long-term preservation by continues perfusion with fluorcarbon emulsion Transplantation 30 1980 43
6. O.N. Reznik, S.F. Bagnenko, and I.V. Loginov The use of oxygenated perfluorocarbonic emulsion for initial in situ kidney perfusion Transplant Proc 40 2008 1027
7. S. Matsumoto, and Y. Kuroda Perfluorocarbon for organ preservation before transplantation Transplantation 74 2002 1804
8. D.G. Maluf, V.R. Mas, and K. Yanek Molecular markers in stored kidney using perfluorocarbon-based preservation solution, preliminary results Transplant Proc 38 2006 1243
9. S. Suzuki, L.H. Toledo-Pereyra, and F.J. Rodriguez Neutrophil infiltration as an important factor in liver ischemia and reperfusion injury. Modulating effects of FK506 and cyclosporine Transplantation 55 1993 1265
10. K. Hashimoto, and C. Miller The use of marginal grafts in liver transplantation J Hepatobiliary Pancreat Surg 15 2008 92
11. R. Mateo, Y. Cho, and G. Singh Risk factors for graft survival after liver transplantation from donation after cardiac death donors: An analysis of OPTN/UNOS data Am J Transplant 6 2006 791
12. L. Triner, M. Verosky, and D.V. Habif Perfusion of isolated liver with fluorocarbon emulsions Fed Proc 29 1970 1778
13. J.K. Brunelle, and N.S. Chandel Oxygen deprivation induced cell death: An update Apoptosis 7 2002 475
14. J.D. Symons, X. Sun, and S.F. Flaim Perflubron emulsion improves tolerance to low-flow ischemia in isolated rabbit hearts J Cardiovasc Pharmacol 34 1999 108
15. S.A. Hosgood, and M.L. Nicholson The role of perfluorocarbon in organ preservation Transplantation 89 2010 1169
16. P.T. Brinkkoetter, H. Song, and R. Losel Hypothermic injury: The mitochondrial calcium, ATP and ROS love-hate triangle out of balance Cell Physiol Biochem 22 2008 195
17. F.O. Belzer, and J.H. Southard The future of kidney preservation Transplantation 30 1980 161
18. T. Minor, and M. Kotting Gaseous oxygen for hypothermic preservation of predamaged liver grafts: Fuel to cellular homeostasis or radical tissue alteration? Cryobiology 40 2000 182
19. T. Minor, M. Sitzia, and F. Dombrowski Kidney transplantation from nonheart-beating donors after oxygenated low-flow machine perfusion preservation with histidine-tryptophan-ketoglutarate solution Transpl Int 17 2005 707
20. S. Ramachandran, N.M. Desai, and T.A. Goers Improved islet yields from pancreas preserved in perfluorocarbon is via inhibition of apoptosis mediated by mitochondrial pathway Am J Transplant2006 6 1696
21. A. Otero, M. Gomez-Gutierrez, and F. Suarez Liver transplantation from Maastricht category 2 non-heart-beating donors Transplantation 76 2003 1068
22. A. Casavilla, C. Ramirez, and R. Shapiro Experience with liver and kidney allografts from non-heart-beating donors Transplantation 59 1995 197
23. A.M. D'Alessandro, R.M. Hoffmann, and S.J. Knechtle Liver transplantation from controlled non-heart-beating donors Surgery 128 2000 579
24. P. Abt, M. Crawford, and N. Desai Liver transplantation from controlled non-heart-beating donors: An increased incidence of biliary complications Transplantation 75 2003 1659
25. E.Y. Chan, L.C. Olson, and J.A. Kisthard Ischemic cholangiopathy following liver transplantation from donation after cardiac death donors Liver Transpl 14 2008 604
26. X.N. Feng, X. Xu, and S.S. Zheng Current status and perspective of liver preservation solutions Hepatobiliary Pancreat Dis Int 5 2006 490
27. C. Moench, K. Moench, and A.W. Lohse Prevention of ischemic-type biliary lesions by arterial back-table pressure perfusion Liver Transpl 9 2003 285
28. A. Maheshwari, W. Maley, and Z. Li Biliary complications and outcomes of liver transplantation from donors after cardiac death Liver Transpl 13 2007 1645
29. R. Merion, S.J. Pelletier, and N. Goodrich Donation after cardiac death as a strategy to increase diseased donor liver availability Ann Surg 244 2006 555
30. K. Bando, S. Teramoto, and M. Tago Oxygenated perfluorocarbon, recombinant human superoxide dismutase, and catalase ameliorate free radical induced myocardial injury during heart preservation and transplantation J Thorac Cardiovasc Surg 96 1988 930
31. W.P. Daugherty, J.E. Levasseur, and D. Sun Perfluorocarbon emulsion improves cerebral oxygenation and mitochondrial function after fluid percussion brain injury in rats Neurosurgery 54 2004 1223
32. M.D. Kay, S.A. Hosgood, and A. Bagul Comparison of preservation solutions in an experimental model of organ cooling in kidney transplantation Br J Surg 96 2009 1215