Targeted and intracellular triggered delivery of therapeutics to cancer cells and the tumor microenvironment: Impact on the treatment of breast cancer

Breast Cancer Research and Treatment

Volumn 133, Issue 1, 2012, Pages 61-73

  Moura, Vera ^a,b   Lacerda, Manuela ^c   Figueiredo, Paulo ^c   Corvo, Maria L ^d   Cruz, Maria E M ^d   Soares, Raquel ^e   De Lima, Maria C Pedroso ^a,f   Simões, Sérgio ^a,b   Moreira, João N ^a,b  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c Instituto Portugues de Oncologia Francisco Gentil Centro Regional de Oncologia de Coimbra SA   (Portugal)

^d RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA   (Portugal)

^e University of Porto   (Portugal)

^f UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Angiogenesis; Breast cancer; Drug targeting; Triggered drug release; Tumor microenvironment

Indexed keywords

CELL NUCLEUS RECEPTOR; DOXORUBICIN; LIPOSOME; MACROGOL; NUCLEOLIN RECEPTOR; UNCLASSIFIED DRUG;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG CYTOTOXICITY; DRUG FORMULATION; DRUG RETENTION; ENDOCYTOSIS; ENDOTHELIUM CELL; EX VIVO STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MASTECTOMY; MOLECULARLY TARGETED THERAPY; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; TUMOR MICROENVIRONMENT; TUMOR NECROSIS; TUMOR REGRESSION;

AGED; AGED, 80 AND OVER; AMINO ACID SEQUENCE; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BREAST NEOPLASMS; CELL LINE, TUMOR; DOXORUBICIN; DRUG DELIVERY SYSTEMS; ENDOTHELIAL CELLS; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; LIPOSOMES; MICE; MICE, INBRED BALB C; MICE, NUDE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MOLECULAR TARGETED THERAPY; NANOCAPSULES; NEOVASCULARIZATION, PATHOLOGIC; PEPTIDES; PHOSPHOPROTEINS; RNA-BINDING PROTEINS; TISSUE DISTRIBUTION; TUMOR MICROENVIRONMENT; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84860334520     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-011-1688-7     Document Type: Article

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