TBI sex dependently upregulates ET-1 to impair autoregulation, which is aggravated by phenylephrine in males but is abrogated in females

Journal of Neurotrauma

Volumn 29, Issue 7, 2012, Pages 1483-1490

  Armstead, William M ^a   Riley, John ^a   Vavilala, Monica S ^b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

cerebral autoregulation; endothelin; K channels; signal transduction; TBI

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN 1; MITOGEN ACTIVATED PROTEIN KINASE; PEGORGOTEIN; PHENYLEPHRINE; POTASSIUM CHANNEL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOREGULATION; BRAIN PERFUSION; CHILDHOOD INJURY; CONTROLLED STUDY; DATA ANALYSIS; FEMALE; HEMODYNAMIC PARAMETERS; HUMAN; HYPOTENSION; HYPOTHESIS; MALE; MEDICAL RECORD; NONHUMAN; PROTEIN BLOOD LEVEL; SEX DIFFERENCE; TRAUMATIC BRAIN INJURY; UPREGULATION; VASODILATATION;

ANIMALS; ANIMALS, NEWBORN; BRAIN INJURIES; ENDOTHELIN-1; FEMALE; HOMEOSTASIS; MALE; PHENYLEPHRINE; SEX CHARACTERISTICS; SWINE; UP-REGULATION;

EID: 84860307850     PISSN: 08977151     EISSN: 15579042     Source Type: Journal    
DOI: 10.1089/neu.2011.2248     Document Type: Article

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