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European Journal of Medicinal Chemistry

Volumn 51, Issue , 2012, Pages 286-293

Structure-activity relationship of selected polyphenol derivatives as inhibitors of Bax/Bcl-xL interaction

(4) Vo, Duc Duy a Gautier, Fabien b,c Juin, Philippe b Grée, René a

a UNIVERSITÉ DE RENNES 1 (France)

b UNIVERSITÉ DE NANTES (France)

c Centre de Recherche en Cancérologie ^* (France)

Author keywords

Apoptosis; Bax; Bcl xL; BRET; Cancer; Phenol

Indexed keywords

4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; [3 (4 FLUOROBENZYL) 4,5 DIMETHOXYPHENYL](4 PHENOXYPHENYL)METHANONE; [5 (4 FLUOROBENZYL) 2,3 DIMETHOXYPHENYL](4 PHENOXYPHENYL)METHANONE; [5 (4 FLUOROBENZYL) 2,3,4 TRIMETHOXYPHENYL](4 PHENOXYPHENYL)METHANONE; POLYPHENOL DERIVATIVE; PROTEIN BAX; PROTEIN BCL XL; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; PROTEIN PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; HELA CELLS; HUMANS; POLYPHENOLS; PROTEIN BINDING; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84860285341 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2012.02.036 Document Type: Article

Times cited : (15)

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