A new analysis approach of epidermal growth factor receptor pathway activation patterns provides insights into cetuximab resistance mechanisms in head and neck cancer

BMC Medicine

Volumn 10, Issue , 2012, Pages

  von der Heyde, Silvia ^a   Beissbarth, Tim ^a  

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

Author keywords

Cetuximab; Drug resistance; EGFR; GSEA; HNSCC; Matrix factorization; Pathway signature

Indexed keywords

CETUXIMAB; EPIDERMAL GROWTH FACTOR RECEPTOR; ANTINEOPLASTIC AGENT; MONOCLONAL ANTIBODY;

CANCER GROWTH; CANCER RESISTANCE; DRUG MECHANISM; GENE EXPRESSION; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; NOTE; SIGNAL TRANSDUCTION; SYSTEMS BIOLOGY; TRANSCRIPTOMICS; ARTICLE; BIOLOGICAL MODEL; DRUG RESISTANCE; GENE EXPRESSION PROFILING; HEAD AND NECK TUMOR; METABOLISM; METHODOLOGY;

ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; DRUG RESISTANCE; GENE EXPRESSION PROFILING; HEAD AND NECK NEOPLASMS; HUMANS; MODELS, BIOLOGICAL; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; SYSTEMS BIOLOGY;

EID: 84860280308     PISSN: None     EISSN: 17417015     Source Type: Journal    
DOI: 10.1186/1741-7015-10-43     Document Type: Note

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