Synthesis and biological evaluation of oleanolic acid derivatives as antitumor agents

Journal of Asian Natural Products Research

Volumn 14, Issue 4, 2012, Pages 355-363

  Chen, Lei ^a   Wu, Jian Bo ^a   Lei, Fan ^a   Qian, Shan ^b   Hai, Li ^a   Wu, Yong ^a  

^a SICHUAN UNIVERSITY   (China)

^b XIHUA UNIVERSITY   (China)

Author keywords

Antitumor; Derivatives; Inhibition ratio; Oleanolic acid; Synthesis

Indexed keywords

2 CYANO 3 OXO 28 (BETA NITRO)VINYLOLEAN 1,12(13) DIENE; 2 CYANO 3 OXOOLEAN 1,12(13) DIEN 28 ALDEHYDE; 2 CYANO 3 OXOOLEAN 1,12(13) DIEN 28 OL; 2 CYANO 3 OXOOLEAN 12(13) EN 28 OL; 2 HYDROXYMETHYLENE 3 OXOOLEAN 12(13) EN 28 OL; 3 OXO 12 EN 28 (2' NITRO VINYL)OLEAN; ANTINEOPLASTIC AGENT; ISOXAZOLO[4, 5 B]OLEAN 12(13) EN 28 OL; OLEAN 12 EN 28 (2' AMINO ETHYL) 3 SPIRO[1',2']DIOXOLANE; OLEAN 12 EN 28 (2' NITRO VINYL) 3 SPIRO [1', 2']DIOXOLANE; OLEAN 12 EN 28 ALDEHYDE 3 SPIRO[1', 2']DIOXOLANE; OLEANIC ACID; OLEANOLIC ACID DERIVATIVE; PACLITAXEL; UNCLASSIFIED DRUG; DRUG DERIVATIVE; OLEANOLIC ACID;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CELL STRAIN COL 02; CELL STRAIN HEPG2; COLON CANCER; CONTROLLED STUDY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION; CHEMICAL STRUCTURE; CHEMISTRY; SYNTHESIS;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; DRUG SCREENING ASSAYS, ANTITUMOR; HEP G2 CELLS; HUMANS; MOLECULAR STRUCTURE; OLEANOLIC ACID; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84860258095     PISSN: 10286020     EISSN: 14772213     Source Type: Journal    
DOI: 10.1080/10286020.2011.654110     Document Type: Article

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