Simultaneous detection of seventeen drugs of abuse and metabolites in hair using solid phase micro extraction (SPME) with GC/MS

Forensic Science International

Volumn 218, Issue 1-3, 2012, Pages 31-36

  Aleksa, Katarina ^a,b   Walasek, Paula ^a   Fulga, Netta ^a   Kapur, Bhushan ^a,c   Gareri, Joey ^a,c   Koren, Gideon ^a,b,c,d  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF WATERLOO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Drugs of abuse; GC MS; Hair

Indexed keywords

3,4 METHYLENEDIOXYAMPHETAMINE; 3,4 METHYLENEDIOXYMETHAMPHETAMINE; AMPHETAMINE; BENZOYLECGONINE; COCAINE; CODEINE; HOMOCOCAINE; HYDROCODONE; HYDROMORPHONE; METHADONE; METHAMPHETAMINE; MORPHINE; MORPHINE 6 ACETATE; NORCOCAINE; OXYCODONE; OXYMORPHONE; PETHIDINE;

ARTICLE; CONTROLLED STUDY; DRUG ABUSE; HAIR ANALYSIS; HAIR LEVEL; HUMAN; HUMAN TISSUE; LIMIT OF DETECTION; LIMIT OF QUANTITATION; MASS FRAGMENTOGRAPHY; PRIORITY JOURNAL; PROCESS DEVELOPMENT; SENSITIVITY AND SPECIFICITY; SOLID PHASE MICROEXTRACTION; VALIDATION PROCESS;

EID: 84860252005     PISSN: 03790738     EISSN: 18726283     Source Type: Journal    
DOI: 10.1016/j.forsciint.2011.10.002     Document Type: Article

References (10)

1. Porter R.S., Kaplan J.L. Drugs in Pregnancy. The Merck Manual On-line Edition 2011, 18th edition.
2. R. Mathias, NIDA Notes: Women and Drugs: NIDA Survey Provides First National Data on Drug Use During Pregnancy 10 (1) (1995).
3. Ontario doctors tackle opioid abuse Oxycontin implicated in increasing numbers of addictions, deaths, CBC News Canada, 08.09.10.
4. Substance Abuse and Mental Health Services Administration, Pregnancy and Illicit Drug Use, NHSDA Report, 31.12.08.
5. Ostrea E.M., Knapp D.K., Tannenbaum L., et al. Estimates of illicit drug use during pregnancy by maternal interview, hair analysis, and meconium analysis. J. Pediatr. 2001, 138:344-348.
6. Moller M., Aleksa K., Walasek P., Karaskov T., Koren G. Solid-phase microextraction for the detection of codeine, morphine and 6-monoacetylmorphine in human hair by gas chromatography-mass spectrometry. Forensic Sci. Int. 2010, 196:64-69.
7. Miguez-Framil M., Moreda-Pineiro A., Bermejo-Barrera P., Lopez P., Tabernero M.J., Bermejo A.M. Improvements on enzymatic hydrolysis of human hair for illicit drug determination by gas chromatography/mass spectrometry. Anal. Chem. 2007, 79:8564-8570.
8. Cordero R., Paterson S. Simultaneous quantification of opiates, amphetamines, cocaine and metabolites and diazepam and metabolite in a single hair sample using GC-MS. J. Chromatogr. B: Anal. Technol. Biomed. Life Sci. 2007, 850:423-431.
9. Barroso M., Dias M., Vieira D.N., Lopez-Rivadulla M., Queiroz J.A. Mixed-mode solid-phase extraction for sample cleanup in hair analysis for methadone and its main metabolite. Biomed. Chromatogr. 2010, 24:1240-1246.
10. Barroso M., Dias M., Vieira D.N., Lopez-Rivadulla M., Queiroz J.A. Simultaneous quantitation of morphine, 6-acetylmorphine, codeine, 6-acetylcodeine and tramadol in hair using mixed-mode solid-phase extraction and gas chromatography-mass spectrometry. Anal. Bioanal. Chem. 2010, 396:3059-3069.