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Volumn 51, Issue 5, 2012, Pages 841-851

Association of NOS2 and potential effect of VEGF, IL6, CCL2 and IL1RN polymorphisms and haplotypes on susceptibility to GCA-a simultaneous study of 130 potentially functional SNPs in 14 candidate genes

Author keywords

Genetic risk; Genetic variation; Giant cell arteritis; Haplotypes; Single nucleotide polymorphism

Indexed keywords

CHEMOKINE RECEPTOR CCR7; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 10; INTERLEUKIN 12P35; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; TUMOR NECROSIS FACTOR; VASCULOTROPIN;

EID: 84860249172     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/ker429     Document Type: Article
Times cited : (37)

References (52)
  • 1
    • 47349103031 scopus 로고    scopus 로고
    • Polymyalgia rheumatica and giant-cell arteritis
    • Salvarani C, Cantini F, Hunder GG. Polymyalgia rheumatica and giant-cell arteritis. Lancet 2008;372:234-45.
    • (2008) Lancet , vol.372 , pp. 234-245
    • Salvarani, C.1    Cantini, F.2    Hunder, G.G.3
  • 2
    • 0024314666 scopus 로고
    • Immunohistochemical analysis of lymphoid and macrophage cell subsets and their immunologic activation markers in temporal arteritis
    • Cid MC, Campo E, Ercilla G et al. Immunohistochemical analysis of lymphoid and macrophage cell subsets and their immunologic activation markers in temporal arteritis. Influence of corticosteroid treatment. Arthritis Rheum 1989;32:884-93.
    • (1989) Influence of corticosteroid treatment. Arthritis Rheum , vol.32 , pp. 884-893
    • Cid, M.C.1    Campo, E.2    Ercilla, G.3
  • 3
    • 0038790045 scopus 로고    scopus 로고
    • Medium- and large-vessel vasculitis
    • Weyand CM, Goronzy JJ. Medium- and large-vessel vasculitis. N Engl J Med 2003;349:160-9.
    • (2003) N Engl J Med , vol.349 , pp. 160-169
    • Weyand, C.M.1    Goronzy, J.J.2
  • 4
    • 33750202397 scopus 로고    scopus 로고
    • Association between increased CCL2 (MCP-1) expression in lesions and persistence of disease activity in giant-cell arteritis
    • Cid MC, Hoffman MP, Hernandez-Rodriguez J et al. Association between increased CCL2 (MCP-1) expression in lesions and persistence of disease activity in giant-cell arteritis. Rheumatology 2006;45:1356-63.
    • (2006) Rheumatology , vol.45 , pp. 1356-1363
    • Cid, M.C.1    Hoffman, M.P.2    Hernandez-Rodriguez, J.3
  • 5
    • 12144286228 scopus 로고    scopus 로고
    • Tissue production of pro-inflammatory cytokines (IL-1beta TNFalpha and IL-6) correlates with the intensity of the systemic inflammatory response and with corticosteroid requirements in giant-cell arteritis
    • Hernandez-Rodriguez J, Segarra M, Vilardell C et al. Tissue production of pro-inflammatory cytokines (IL-1beta, TNFalpha and IL-6) correlates with the intensity of the systemic inflammatory response and with corticosteroid requirements in giant-cell arteritis. Rheumatology 2004;43:294-301.
    • (2004) Rheumatology , vol.43 , pp. 294-301
    • Hernandez-Rodriguez, J.1    Segarra, M.2    Vilardell, C.3
  • 6
    • 0032885563 scopus 로고    scopus 로고
    • Formation of new vasa vasorum in vasculitis Production of angiogenic cytokines by multinucleated giant cells
    • Kaiser M, Younge B, Bjornsson J et al. Formation of new vasa vasorum in vasculitis. Production of angiogenic cytokines by multinucleated giant cells. Am J Pathol 1999; 155:765-74.
    • (1999) Am J Pathol , vol.155 , pp. 765-774
    • Kaiser, M.1    Younge, B.2    Bjornsson, J.3
  • 7
    • 54349106248 scopus 로고    scopus 로고
    • Imatinib mesylate inhibits in vitro and ex vivo biological responses related to vascular occlusion in giant cell arteritis
    • Lozano E, Segarra M, Garcia-Martinez A et al. Imatinib mesylate inhibits in vitro and ex vivo biological responses related to vascular occlusion in giant cell arteritis. Ann Rheum Dis 2008;67:1581-8.
    • (2008) Ann Rheum Dis , vol.67 , pp. 1581-1588
    • Lozano, E.1    Segarra, M.2    Garcia-Martinez, A.3
  • 8
    • 35648987258 scopus 로고    scopus 로고
    • Gelatinase expression and proteolytic activity in giant-cell arteritis
    • Segarra M, Garcia-Martinez A, Sanchez M et al. Gelatinase expression and proteolytic activity in giant-cell arteritis. Ann Rheum Dis 2007;66:1429-35.
    • (2007) Ann Rheum Dis , vol.66 , pp. 1429-1435
    • Segarra, M.1    Garcia-Martinez, A.2    Sanchez, M.3
  • 9
    • 0037504410 scopus 로고    scopus 로고
    • Elevated production of interleukin-6 is associated with a lower incidence of disease-related ischemic events in patients with giant-cell arteritis: angiogenic activity of interleukin-6 as a potential protective mechanism
    • Hernandez-Rodriguez J, Segarra M, Vilardell C et al. Elevated production of interleukin-6 is associated with a lower incidence of disease-related ischemic events in patients with giant-cell arteritis: angiogenic activity of interleukin-6 as a potential protective mechanism. Circulation 2003;107:2428-34.
    • (2003) Circulation , vol.107 , pp. 2428-2434
    • Hernandez-Rodriguez, J.1    Segarra, M.2    Vilardell, C.3
  • 10
    • 77953087545 scopus 로고    scopus 로고
    • Clinical relevance of persistently elevated circulating cytokines (tumor necrosis factor alpha and interleukin-6) in the long-term followup of patients with giant cell arteritis
    • Garcia-Martinez A, Hernandez-Rodriguez J, Espigol-Frigole G et al. Clinical relevance of persistently elevated circulating cytokines (tumor necrosis factor alpha and interleukin-6) in the long-term followup of patients with giant cell arteritis. Arthritis Care Res 2010;62:835-41.
    • (2010) Arthritis Care Res , vol.62 , pp. 835-841
    • Garcia-Martinez, A.1    Hernandez-Rodriguez, J.2    Espigol-Frigole, G.3
  • 11
    • 0028118616 scopus 로고
    • Familial giant cell arteritis: report of an HLA-typed sibling pair and a review of the literature
    • Wernick R, Davey M, Bonafede P. Familial giant cell arteritis: report of an HLA-typed sibling pair and a review of the literature. Clin Exp Rheumatol 1994;12:63-6.
    • (1994) Clin Exp Rheumatol , vol.12 , pp. 63-66
    • Wernick, R.1    Davey, M.2    Bonafede, P.3
  • 12
    • 0041826780 scopus 로고    scopus 로고
    • Genetic markers of disease susceptibility and severity in giant cell arteritis and polymyalgia rheumatica
    • Gonzalez-Gay MA, Amoli MM, Garcia-Porrua C et al. Genetic markers of disease susceptibility and severity in giant cell arteritis and polymyalgia rheumatica. Semin Arthritis Rheum 2003;33:38-48.
    • (2003) Semin Arthritis Rheum , vol.33 , pp. 38-48
    • Gonzalez-Gay, M.A.1    Amoli, M.M.2    Garcia-Porrua, C.3
  • 13
    • 0023922162 scopus 로고
    • Polymyalgia rheumatica: a syndrome associated with HLA-DR4 antigen
    • Cid MC, Ercilla G, Vilaseca J et al. Polymyalgia rheumatica: a syndrome associated with HLA-DR4 antigen. Arthritis Rheum 1988;31:678-82.
    • (1988) Arthritis Rheum , vol.31 , pp. 678-682
    • Cid, M.C.1    Ercilla, G.2    Vilaseca, J.3
  • 14
    • 77955274178 scopus 로고    scopus 로고
    • Pathogenesis of giant cell arteritis: more than just an inflammatory condition?
    • Ly KH, Regent A, Tamby MC et al. Pathogenesis of giant cell arteritis: more than just an inflammatory condition? Autoimmun Rev 2010;9:635-45.
    • (2010) Autoimmun Rev , vol.9 , pp. 635-645
    • Ly, K.H.1    Regent, A.2    Tamby, M.C.3
  • 15
    • 55849093927 scopus 로고    scopus 로고
    • Giant cell arteritis and polymyalgia rheumatica: role of cytokines in the pathogenesis and implications for treatment
    • Martinez-Taboada VM, Alvarez L, RuizSoto M et al. Giant cell arteritis and polymyalgia rheumatica: role of cytokines in the pathogenesis and implications for treatment. Cytokine 2008;44:207-20.
    • (2008) Cytokine , vol.44 , pp. 207-220
    • Martinez-Taboada, V.M.1    Alvarez, L.2    RuizSoto, M.3
  • 16
    • 0025976087 scopus 로고
    • Epidemiologic and immunogenetic aspects of polymyalgia rheumatica and giant cell arteritis in northern Italy
    • Salvarani C, Macchioni P, Zizzi F et al. Epidemiologic and immunogenetic aspects of polymyalgia rheumatica and giant cell arteritis in northern Italy. Arthritis Rheum 1991; 34:351-6.
    • (1991) Arthritis Rheum , vol.34 , pp. 351-356
    • Salvarani, C.1    Macchioni, P.2    Zizzi, F.3
  • 17
    • 70450278797 scopus 로고    scopus 로고
    • Interleukin-12 gene polymorphisim in patients with giant cell arteritis, polymyalgia rheumatica and elderly-onset rheumatoid arthritis
    • Alvarez-Rodriguez L, Martinez-Taboada VM, Lopez-Hoyos M et al. Interleukin-12 gene polymorphisim in patients with giant cell arteritis, polymyalgia rheumatica and elderly-onset rheumatoid arthritis. Clin Exp Rheumatol 2009;27:S14-18.
    • (2009) Clin Exp Rheumatol , vol.27
    • Alvarez-Rodriguez, L.1    Martinez-Taboada, V.M.2    Lopez-Hoyos, M.3
  • 18
    • 10044259869 scopus 로고    scopus 로고
    • Epistatic interactions between HLA-DRB1 and interleukin 4, but not interferon-gamma, increase susceptibility to giant cell arteritis
    • Amoli MM, Gonzalez-Gay MA, Zeggini E et al. Epistatic interactions between HLA-DRB1 and interleukin 4, but not interferon-gamma, increase susceptibility to giant cell arteritis. J Rheumatol 2004;31: 2413-7.
    • (2004) J Rheumatol , vol.31 , pp. 2413-2417
    • Amoli, M.M.1    Gonzalez-Gay, M.A.2    Zeggini, E.3
  • 19
    • 33845633733 scopus 로고    scopus 로고
    • Interleukin-10 promoter polymorphisms in giant cell arteritis
    • Boiardi L, Casali B, Farnetti E et al. Interleukin-10 promoter polymorphisms in giant cell arteritis. Arthritis Rheum 2006;54:4011-7.
    • (2006) Arthritis Rheum , vol.54 , pp. 4011-4017
    • Boiardi, L.1    Casali, B.2    Farnetti, E.3
  • 20
    • 15044361959 scopus 로고    scopus 로고
    • Interferon-gamma gene microsatellite polymorphisms in patients with biopsy-proven giant cell arteritis and isolated polymyalgia rheumatica
    • Gonzalez-Gay MA, Hajeer AH, Dababneh A et al. Interferon-gamma gene microsatellite polymorphisms in patients with biopsy-proven giant cell arteritis and isolated polymyalgia rheumatica. Clin Exp Rheumatol 2004;22: S18-20.
    • (2004) Clin Exp Rheumatol , vol.22
    • Gonzalez-Gay, M.A.1    Hajeer, A.H.2    Dababneh, A.3
  • 21
    • 0035990166 scopus 로고    scopus 로고
    • IL-6 promoter polymorphism at position -174 modulates the phenotypic expression of polymyalgia rheumatica in biopsy-proven giant cell arteritis
    • Gonzalez-Gay MA, Hajeer AH, Dababneh A et al. IL-6 promoter polymorphism at position -174 modulates the phenotypic expression of polymyalgia rheumatica in biopsy-proven giant cell arteritis. Clin Exp Rheumatol 2002;20:179-84.
    • (2002) Clin Exp Rheumatol , vol.20 , pp. 179-184
    • Gonzalez-Gay, M.A.1    Hajeer, A.H.2    Dababneh, A.3
  • 22
    • 0036558981 scopus 로고    scopus 로고
    • Lack of association between IL-1 cluster and TNF-alpha gene polymorphisms and giant cell arteritis
    • Gonzalez-Gay MA, Di Giovine FS, Silvestri T et al. Lack of association between IL-1 cluster and TNF-alpha gene polymorphisms and giant cell arteritis. Clin Exp Rheumatol 2002;20:431.
    • (2002) Clin Exp Rheumatol , vol.20 , pp. 431
    • Gonzalez-Gay, M.A.1    Di Giovine, F.S.2    Silvestri, T.3
  • 23
    • 15044361959 scopus 로고    scopus 로고
    • Interferon-gamma gene microsatellite polymorphisms in patients with biopsy-proven giant cell arteritis and isolated polymyalgia rheumatica
    • Gonzalez-Gay MA, Hajeer AH, Dababneh A et al. Interferon-gamma gene microsatellite polymorphisms in patients with biopsy-proven giant cell arteritis and isolated polymyalgia rheumatica. Clin Exp Rheumatol 2004;22: S18-20.
    • (2004) Clin Exp Rheumatol , vol.22
    • Gonzalez-Gay, M.A.1    Hajeer, A.H.2    Dababneh, A.3
  • 24
    • 0033897330 scopus 로고    scopus 로고
    • Association of giant cell arteritis and polymyalgia rheumatica with different tumor necrosis factor microsatellite polymorphisms
    • Mattey DL, Hajeer AH, Dababneh A et al. Association of giant cell arteritis and polymyalgia rheumatica with different tumor necrosis factor microsatellite polymorphisms. Arthritis Rheum 2000;43:1749-55.
    • (2000) Arthritis Rheum , vol.43 , pp. 1749-1755
    • Mattey, D.L.1    Hajeer, A.H.2    Dababneh, A.3
  • 25
    • 34447514112 scopus 로고    scopus 로고
    • Influence of interleukin promoter polymorphisms in susceptibility to giant cell arteritis in northwestern Spain
    • Rueda B, Roibas B, Martin J et al. Influence of interleukin promoter polymorphisms in susceptibility to giant cell arteritis in northwestern Spain. J Rheumatol 2007;34: 1535-9.
    • (2007) J Rheumatol , vol.34 , pp. 1535-1539
    • Rueda, B.1    Roibas, B.2    Martin, J.3
  • 26
    • 27744518363 scopus 로고    scopus 로고
    • Interleukin-6 promoter polymorphism at position -174 in giant cell arteritis
    • Salvarani C, Casali B, Farnetti E et al. Interleukin-6 promoter polymorphism at position -174 in giant cell arteritis. J Rheumatol 2005;32:2173-7.
    • (2005) J Rheumatol , vol.32 , pp. 2173-2177
    • Salvarani, C.1    Casali, B.2    Farnetti, E.3
  • 27
    • 0036840232 scopus 로고    scopus 로고
    • Trapping of misdirected dendritic cells in the granulomatous lesions of giant cell arteritis
    • Krupa WM, Dewan M, Jeon MS et al. Trapping of misdirected dendritic cells in the granulomatous lesions of giant cell arteritis. Am J Pathol 2002;161:1815-23.
    • (2002) Am J Pathol , vol.161 , pp. 1815-1823
    • Krupa, W.M.1    Dewan, M.2    Jeon, M.S.3
  • 28
    • 0033553413 scopus 로고    scopus 로고
    • Tissue-destructive macrophages in giant cell arteritis
    • Rittner HL, Kaiser M, Brack A et al. Tissue-destructive macrophages in giant cell arteritis. Circ Res 1999;84: 1050-8.
    • (1999) Circ Res , vol.84 , pp. 1050-1058
    • Rittner, H.L.1    Kaiser, M.2    Brack, A.3
  • 29
    • 0028082171 scopus 로고
    • Distinct vascular lesions in giant cell arteritis share identical T cell clonotypes
    • Weyand CM, Schonberger J, Oppitz U et al. Distinct vascular lesions in giant cell arteritis share identical T cell clonotypes. J Exp Med 1994;179:951-60.
    • (1994) J Exp Med , vol.179 , pp. 951-960
    • Weyand, C.M.1    Schonberger, J.2    Oppitz, U.3
  • 30
    • 23144454259 scopus 로고    scopus 로고
    • PupasView: a visual tool for selecting suitable SNPs, with putative pathological effect in genes, for genotyping purposes
    • Conde L, Vaquerizas JM, Ferrer-Costa C et al. PupasView: a visual tool for selecting suitable SNPs, with putative pathological effect in genes, for genotyping purposes. Nucleic Acids Res 2005;33:W501-5.
    • (2005) Nucleic Acids Res , vol.33
    • Conde, L.1    Vaquerizas, J.M.2    Ferrer-Costa, C.3
  • 31
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: analysis and visualization of LD and haplotype maps
    • Barrett JC, Fry B, Maller J et al. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005;21:263-5.
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3
  • 32
    • 79959503826 scopus 로고    scopus 로고
    • The International HapMap, Project
    • The International HapMap Project. Nature 2003;426: 789-96.
    • (2003) Nature , vol.426 , pp. 789-796
  • 33
    • 1642295096 scopus 로고    scopus 로고
    • Assessing the probability that a positive report is false: an approach for molecular epidemiology studies
    • Wacholder S, Chanock S, Garcia-Closas M et al. Assessing the probability that a positive report is false: an approach for molecular epidemiology studies. J Natl Cancer Inst 2004;96:434-42.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 434-442
    • Wacholder, S.1    Chanock, S.2    Garcia-Closas, M.3
  • 34
    • 18444369013 scopus 로고    scopus 로고
    • The structure of haplotype blocks in the human genome
    • Gabriel SB, Schaffner SF, Nguyen H et al. The structure of haplotype blocks in the human genome. Science 2002; 296:2225-9.
    • (2002) Science , vol.296 , pp. 2225-2229
    • Gabriel, S.B.1    Schaffner, S.F.2    Nguyen, H.3
  • 35
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: a tool set for whole-genome association and populationbased linkage analyses
    • Purcell S, Neale B, Todd-Brown K et al. PLINK: a tool set for whole-genome association and populationbased linkage analyses. Am J Hum Genet 2007;81: 559-75.
    • (2007) Am J Hum Genet , vol.81 , pp. 559-575
    • Purcell, S.1    Neale, B.2    Todd-Brown, K.3
  • 36
    • 0031961899 scopus 로고    scopus 로고
    • Association between strong inflammatory response and low risk of developing visual loss and other cranial ischemic complications in giant cell (temporal) arteritis
    • Cid MC, Font C, Oristrell J et al. Association between strong inflammatory response and low risk of developing visual loss and other cranial ischemic complications in giant cell (temporal) arteritis. Arthritis Rheum 1998;41: 26-32.
    • (1998) Arthritis Rheum , vol.41 , pp. 26-32
    • Cid, M.C.1    Font, C.2    Oristrell, J.3
  • 37
    • 0034769118 scopus 로고    scopus 로고
    • Nitric oxide and the immune response
    • Bogdan C. Nitric oxide and the immune response. Nat Immunol 2001;2:907-16.
    • (2001) Nat Immunol , vol.2 , pp. 907-916
    • Bogdan, C.1
  • 38
    • 78649736380 scopus 로고    scopus 로고
    • The regulatory role of nitric oxide in proinflammatory cytokine expression during the induction and resolution of inflammation
    • Kobayashi Y. The regulatory role of nitric oxide in proinflammatory cytokine expression during the induction and resolution of inflammation. J Leukoc Biol 2010;88: 1157-62.
    • (2010) J Leukoc Biol , vol.88 , pp. 1157-1162
    • Kobayashi, Y.1
  • 39
    • 0032827117 scopus 로고    scopus 로고
    • Genotyping and functional analysis of a polymorphic (CCTTT)(n) repeat of NOS2A in diabetic retinopathy
    • Warpeha KM, Xu W, Liu L et al. Genotyping and functional analysis of a polymorphic (CCTTT)(n) repeat of NOS2A in diabetic retinopathy. FASEB J 1999;13: 1825-32.
    • (1999) FASEB J , vol.13 , pp. 1825-1832
    • Warpeha, K.M.1    Xu, W.2    Liu, L.3
  • 40
    • 27744480043 scopus 로고    scopus 로고
    • Association of a functional inducible nitric oxide synthase promoter variant with susceptibility to biopsy-proven giant cell arteritis
    • Gonzalez-Gay MA, Oliver J, Sanchez E et al. Association of a functional inducible nitric oxide synthase promoter variant with susceptibility to biopsy-proven giant cell arteritis. J Rheumatol 2005;32:2178-82.
    • (2005) J Rheumatol , vol.32 , pp. 2178-2182
    • Gonzalez-Gay, M.A.1    Oliver, J.2    Sanchez, E.3
  • 41
    • 33646107369 scopus 로고    scopus 로고
    • VEGF receptor signalling - in control of vascular function
    • Olsson AK, Dimberg A, Kreuger J et al. VEGF receptor signalling - in control of vascular function. Nat Rev Mol Cell Biol 2006;7:359-71.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 359-371
    • Olsson, A.K.1    Dimberg, A.2    Kreuger, J.3
  • 42
    • 70349499022 scopus 로고    scopus 로고
    • The role of vascular endothelial growth factor SNPs as predictive and prognostic markers for major solid tumors
    • Jain L, Vargo CA, Danesi R et al. The role of vascular endothelial growth factor SNPs as predictive and prognostic markers for major solid tumors. Mol Cancer Ther 2009;8:2496-508.
    • (2009) Mol Cancer Ther , vol.8 , pp. 2496-2508
    • Jain, L.1    Vargo, C.A.2    Danesi, R.3
  • 43
    • 0032960891 scopus 로고    scopus 로고
    • Vascular endothelial growth factor activates nuclear factor-kappaB and induces monocyte chemoattractant protein-1 in bovine retinal endothelial cells
    • Marumo T, Schini-Kerth VB, Busse R. Vascular endothelial growth factor activates nuclear factor-kappaB and induces monocyte chemoattractant protein-1 in bovine retinal endothelial cells. Diabetes 1999;48:1131-7.
    • (1999) Diabetes , vol.48 , pp. 1131-1137
    • Marumo, T.1    Schini-Kerth, V.B.2    Busse, R.3
  • 44
    • 10744228051 scopus 로고    scopus 로고
    • Vascular endothelial growth factor gene polymorphisms in giant cell arteritis
    • Boiardi L, Casali B, Nicoli D et al. Vascular endothelial growth factor gene polymorphisms in giant cell arteritis. J Rheumatol 2003;30:2160-4.
    • (2003) J Rheumatol , vol.30 , pp. 2160-2164
    • Boiardi, L.1    Casali, B.2    Nicoli, D.3
  • 45
    • 0035208145 scopus 로고    scopus 로고
    • New vascular endothelial growth factor isoform generated by internal ribosome entry site-driven CUG translation initiation
    • Huez I, Bornes S, Bresson D et al. New vascular endothelial growth factor isoform generated by internal ribosome entry site-driven CUG translation initiation. Mol Endocrinol 2001;15:2197-210.
    • (2001) Mol Endocrinol , vol.15 , pp. 2197-2210
    • Huez, I.1    Bornes, S.2    Bresson, D.3
  • 46
    • 0031741862 scopus 로고    scopus 로고
    • Two independent internal ribosome entry sites are involved in translation initiation of vascular endothelial growth factor mRNA
    • Huez I, Creancier L, Audigier S et al. Two independent internal ribosome entry sites are involved in translation initiation of vascular endothelial growth factor mRNA. Mol Cell Biol 1998;18:6178-90.
    • (1998) Mol Cell Biol , vol.18 , pp. 6178-6190
    • Huez, I.1    Creancier, L.2    Audigier, S.3
  • 47
    • 0041903805 scopus 로고    scopus 로고
    • VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death
    • Lambrechts D, Storkebaum E, Morimoto M et al. VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death. Nat Genet 2003;34:383-94.
    • (2003) Nat Genet , vol.34 , pp. 383-394
    • Lambrechts, D.1    Storkebaum, E.2    Morimoto, M.3
  • 48
    • 0028362019 scopus 로고
    • Multiple regulatory elements in the interleukin-6 gene mediate induction by prostaglandins, cyclic AMP, and lipopolysaccharide
    • Dendorfer U, Oettgen P, Libermann TA. Multiple regulatory elements in the interleukin-6 gene mediate induction by prostaglandins, cyclic AMP, and lipopolysaccharide. Mol Cell Biol 1994;14:4443-54.
    • (1994) Mol Cell Biol , vol.14 , pp. 4443-4454
    • Dendorfer, U.1    Oettgen, P.2    Libermann, T.A.3
  • 49
    • 0032189103 scopus 로고    scopus 로고
    • The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis
    • Fishman D, Faulds G, Jeffery R et al. The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis. J Clin Invest 1998;102:1369-76.
    • (1998) J Clin Invest , vol.102 , pp. 1369-1376
    • Fishman, D.1    Faulds, G.2    Jeffery, R.3
  • 50
    • 33645800794 scopus 로고    scopus 로고
    • Relationship between interleukin 6 promoter polymorphism at position -174, IL-6 serum levels, and the risk of relapse/recurrence in polymyalgia rheumatica
    • Boiardi L, Casali B, Farnetti E et al. Relationship between interleukin 6 promoter polymorphism at position -174, IL-6 serum levels, and the risk of relapse/recurrence in polymyalgia rheumatica. J Rheumatol 2006;33:703-8.
    • (2006) J Rheumatol , vol.33 , pp. 703-708
    • Boiardi, L.1    Casali, B.2    Farnetti, E.3
  • 51
    • 0035715670 scopus 로고    scopus 로고
    • Influence of the IL-1Ra gene polymorphism on in vivo synthesis of IL-1Ra and IL-1beta after live yellow fever vaccination
    • Hacker UT, Erhardt S, Tschop K et al. Influence of the IL-1Ra gene polymorphism on in vivo synthesis of IL-1Ra and IL-1beta after live yellow fever vaccination. Clin Exp Immunol 2001;125:465-9.
    • (2001) Clin Exp Immunol , vol.125 , pp. 465-469
    • Hacker, U.T.1    Erhardt, S.2    Tschop, K.3
  • 52
    • 58149468067 scopus 로고    scopus 로고
    • Interleukin-1RN gene polymorphisms in elderly patients with rheumatic inflammatory chronic conditions: association of IL-1RN*2/2 genotype with polymyalgia rheumatica
    • Alvarez-Rodriguez L, Carrasco-Marin E, Lopez-Hoyos M et al. Interleukin-1RN gene polymorphisms in elderly patients with rheumatic inflammatory chronic conditions: association of IL-1RN*2/2 genotype with polymyalgia rheumatica. Hum Immunol 2009;70:49-54.
    • (2009) Hum Immunol , vol.70 , pp. 49-54
    • Alvarez-Rodriguez, L.1    Carrasco-Marin, E.2    Lopez-Hoyos, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.