Tissue-destructive macrophages in giant cell arteritis

Circulation Research

Volumn 84, Issue 9, 1999, Pages 1050-1058

  Rittner, Heike L ^a   Kaiser, Markus ^a   Brack, Alexander ^a   Szweda, Luke I ^b   Goronzy, Jörg J ^a   Weyand, Cornelia M ^a  

^a MAYO CLINIC   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Macrophage; Metalloproteinase; Reactive oxygen species; Vasculitis

Indexed keywords

CD68 ANTIGEN; METALLOPROTEINASE; REACTIVE OXYGEN METABOLITE;

ANTIBODY SPECIFICITY; ANTIGEN ANTIBODY COMPLEX; ARTERY OCCLUSION; ARTERY WALL; ARTICLE; BLOOD VESSEL FUNCTION; CLINICAL ARTICLE; GENE EXPRESSION; GENETIC TRANSCRIPTION; GIANT CELL ARTERITIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MACROPHAGE FUNCTION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SYNTHESIS; VASCULITIS;

EID: 0033553413     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.84.9.1050     Document Type: Article

References (27)

1. Huston KA, Hunder GG. Giant cell (cranial) arteritis: a clinical review. Am Heart J. 1980;100:99-105.
2. Weyand CM, Bartley GB. Giant cell arteritis: new concepts in pathogenesis and implications for management. Am J Ophthalmol. 1997;123: 392-395.
3. Evans JM, O'Fallon WM, Hunder GG. Increased incidence of aortic aneurysm and dissection in giant cell (temporal) arteritis: a population-based study. Ann Intern Med. 1995;122:502-507.
4. Martinez-Taboada V, Hunder NN, Hunder GG, Weyand CM, Goronzy JJ. Recognition of tissue residing antigen by T cells in vasculitic lesions of giant cell arteritis. J Mol Med. 1996;74:695-703.
5. Wagner AD, Björnsson J, Bartley GB, Goronzy JJ, Weyand CM. Interferon-gamma-producing T cells in giant cell vasculitis represent a minority of tissue-infiltrating cells and are located distant from the site of pathology. Am J Pathol. 1996;148:1925-1933.
6. Weyand CM, Wagner AD, Björnsson J, Goronzy JJ. Correlation of the topographical arrangement and the functional pattern of tissue-infiltrating macrophages in giant cell arteritis. J Clin Invest. 1996;98:1642-1649.
7. + cells in giant cell arteritis: evidence for two components of the disease. J Clin Invest. 1994;94:1134-1140.
8. Sorbi D, French DL, Nuovo GJ, Kew RR, Arbeit LA, Gruber BL. Elevated levels of 92-kd type IV collagenase (matrix metalloproteinase 9) in giant cell arteritis. Arthritis Rheum. 1996;39:1747-1753.
9. Murphy G, Willenbrock F, Crabbe T, O'Shea M, Ward R, Atkinson S, O'Connell J, Docherty A. Regulation of matrix metalloproteinase activity. Ann N Y Acad Sci. 1994;732:31-41.
10. Clancy RM, Abramson SB. Nitric oxide: a novel mediator of inflammation. Proc Soc Exp Biol Med. 1995;210:93-101.
11. Liang P, Pardee AB. Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. Science. 1992;257:967-971.
12. Esterbauer H, Schaur RJ, Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med. 1991;11:81-128.
13. Li Z, Li L, Zielke HR, Cheng L, Xiao R, Crow MT, Stetler-Stevenson WG, Froehlich J, Lakatta EG. Increased expression of 72-kd type IV collagenase (MMP-2) in human aortic atherosclerotic lesions. Am J Pathol. 1996;148:121-128.
14. Uchida K, Szweda LI, Chae HZ, Stadtman ER. Immunochemical detection of 4-hydroxynonenal protein adducts in oxidized hepatocytes. Proc Natl Acad Sci U S A. 1993;90:8742-8746.
15. Bedetti CD. Immunocytochemical demonstration of cytochrome c oxidase with an immunoperoxidase method: a specific stain for mitochondria in formalin-fixed and paraffin-embedded human tissues. J Histochem Cytochem. 1985;33:446-452.
16. Esterbauer H, Benedetti A, Lang J, Fulceri R, Fauler G, Comporta M. Studies on the mechanism of formation of 4-hydroxynonenal during microsomal lipid peroxidation. Biochim Biophys Acta. 1986;876: 154-166.
17. Rajagopalan S, Meng XP, Ramasamy S, Harrison DG, Galis ZS. Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro: implications for atherosclerotic plaque stability. J Clin Invest. 1996;98:2572-2579.
18. Liu G, Shupak R, Chiu BK. Aortic dissection in giant-cell arteritis. Semin Arthritis Rheum. 1995;25:160-171.
19. Ginsburg R. Aortic aneurysm and dissection in giant cell arteritis. Ann Intern Med. 1996;124:615. Letter.
20. Porges AJ, Redecha PB, Kimberly WT. Csernok E, Gross WL, Kimberly RP. Anti-neutrophil cytoplasmic antibodies engage and activate human neutrophils via Fc gamma RIIa. J Immunol. 1994;153:1271-1280.
21. Chensue SW, Quinlan L, Higashi GI, Kunkel SL. Role of oxygen reactive species in Schistosoma mansoni egg-induced granulomatous inflammation. Biochem Biophys Res Commun. 1984;122:184-190.
22. Jones OT. The regulation of superoxide production by the NADPH oxidase of neutrophils and other mammalian cells. Bioessays. 1994;16: 919-923.
23. Musson RA, McPhail LC, Shafran H, Johnston RB Jr. Differences in the ability of human peripheral blood monocytes and in vitro monocyte-derived macrophages to produce superoxide anion: studies with cells from normals and patients with chronic granulomatous disease. J Reticuloendothel Soc. 1982;31:261-266.
24. Weyand CM, Goronzy JJ. Arterial wall injury in giant cell arteritis. Arthritis Rheum. In press.
25. Kaiser M, Weyand CM, Bjornsson J, Goronzy JJ. Platelet-derived growth factor, intimai hyperplasia, and ischemic complications in giant cell arteritis. Arthritis Rheum. 1998;4:623-633.
26. Brack A, Rittner HL, Younge BR, Kaltschmidt C, Weyand CM, Goronzy JJ. Glucocorticoid-mediated repression of cytokine gene transcription in human arteritis-SCID chimeras. J Clin Invest. 1997;99:2842-2850.
27. Brack A, Geisler A, Martinez-Taboada VM, Younge BR, Goronzy JJ, Weyand CM. Giant cell arteritis is a T cell dependent disease. Mol Med. 1997;3:530-543.