메뉴 건너뛰기




Volumn 26, Issue 2, 2012, Pages 141-151

Gastrointestinal lesions and complications of low-dose aspirin in the gastrointestinal tract

Author keywords

Gastrointestinal bleeding; Low dose aspirin; Mortality; Time trends

Indexed keywords

ACETYLSALICYLIC ACID; BICARBONATE; CALGRANULIN; CLOPIDOGREL; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN SYNTHASE; THROMBOXANE A2;

EID: 84860237358     PISSN: 15216918     EISSN: 15321916     Source Type: Journal    
DOI: 10.1016/j.bpg.2012.01.016     Document Type: Article
Times cited : (26)

References (78)
  • 1
    • 65849268320 scopus 로고    scopus 로고
    • Aspirin in the primary and secondary prevention of vascular disease: Collaborative meta-analysis of individual participant data from randomised trials
    • C. Baigent, L. Blackwell, R. Collins, J. Emberson, J. Godwin, and R. Peto Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials Lancet 373 2009 1849 1860
    • (2009) Lancet , vol.373 , pp. 1849-1860
    • Baigent, C.1    Blackwell, L.2    Collins, R.3    Emberson, J.4    Godwin, J.5    Peto, R.6
  • 3
    • 72549091052 scopus 로고    scopus 로고
    • National Health Service Information Centre Available at: [accessed 21.10.11]
    • National Health Service Information Centre Prescription cost analysis for England 2007 2008 Available at: http://www.ic.nhs.uk/webfiles/publications/ PCA%20publication/PCA%202007%20complete%20V2.pdf [accessed 21.10.11]
    • (2008) Prescription Cost Analysis for England 2007
  • 5
    • 27644558549 scopus 로고    scopus 로고
    • Prevalence and incidence of gastroduodenal ulcers during treatment with vascular protective doses of aspirin
    • N.D. Yeomans, A.I. Lanas, N.J. Talley, A.B. Thomson, R. Daneshjoo, and B. Eriksson Prevalence and incidence of gastroduodenal ulcers during treatment with vascular protective doses of aspirin Aliment Pharmacol Ther 22 2005 795 801
    • (2005) Aliment Pharmacol Ther , vol.22 , pp. 795-801
    • Yeomans, N.D.1    Lanas, A.I.2    Talley, N.J.3    Thomson, A.B.4    Daneshjoo, R.5    Eriksson, B.6
  • 6
    • 54049118496 scopus 로고    scopus 로고
    • ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use: A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents
    • D.L. Bhatt, J. Scheiman, N.S. Abraham, E.M. Antman, F.K. Chan, and C.D. Furberg ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use: a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents J Am Coll Cardiol 52 2008 1502 1517
    • (2008) J Am Coll Cardiol , vol.52 , pp. 1502-1517
    • Bhatt, D.L.1    Scheiman, J.2    Abraham, N.S.3    Antman, E.M.4    Chan, F.K.5    Furberg, C.D.6
  • 7
    • 78650443125 scopus 로고    scopus 로고
    • Gastrointestinal bleeding associated with low-dose aspirin use: Relevance and management in clinical practice
    • A. Lanas Gastrointestinal bleeding associated with low-dose aspirin use: relevance and management in clinical practice Expert Opin Drug Saf 10 1 2011 Jan 45 54
    • (2011) Expert Opin Drug Saf , vol.10 , Issue.1 , pp. 45-54
    • Lanas, A.1
  • 8
    • 84860236271 scopus 로고    scopus 로고
    • Prevalence and clinical impact of upper gastrointestinal symptoms in subjects treated with low dose aspirin: The UGLA survey
    • G. Cayla, J.P. Collet, J. Silvain, G. Thiefin, F. Woimant, and G. Montalescot Prevalence and clinical impact of upper gastrointestinal symptoms in subjects treated with low dose aspirin: the UGLA survey Int J Cardiol 2010 Nov 17
    • (2010) Int J Cardiol
    • Cayla, G.1    Collet, J.P.2    Silvain, J.3    Thiefin, G.4    Woimant, F.5    Montalescot, G.6
  • 9
    • 79960671735 scopus 로고    scopus 로고
    • Discontinuation of low-dose acetylsalicylic acid treatment for secondary prevention of cardiovascular outcomes
    • L.A. García Rodríguez, L. Cea Soriano, E. Martín-Merino, and S. Johansson Discontinuation of low-dose acetylsalicylic acid treatment for secondary prevention of cardiovascular outcomes Circulation 120 2009 S480
    • (2009) Circulation , vol.120 , pp. 480
    • García Rodríguez, L.A.1    Cea Soriano, L.2    Martín-Merino, E.3    Johansson, S.4
  • 10
    • 6444220783 scopus 로고    scopus 로고
    • Impact of prior use or recent withdrawal of oral antiplatelet agents on acute coronary syndromes
    • J.P. Collet, G. Montalescot, B. Blanchet, M.L. Tanguy, J.L. Golmard, and R. Choussat Impact of prior use or recent withdrawal of oral antiplatelet agents on acute coronary syndromes Circulation 110 2004 2361 2367
    • (2004) Circulation , vol.110 , pp. 2361-2367
    • Collet, J.P.1    Montalescot, G.2    Blanchet, B.3    Tanguy, M.L.4    Golmard, J.L.5    Choussat, R.6
  • 11
    • 23844481806 scopus 로고    scopus 로고
    • Effect of discontinuing aspirin therapy on the risk of brain ischemic stroke
    • A.B. Maulaz, D.C. Bezerra, P. Michel, and J. Bogousslavsky Effect of discontinuing aspirin therapy on the risk of brain ischemic stroke Arch Neurol 62 2005 1217 1220
    • (2005) Arch Neurol , vol.62 , pp. 1217-1220
    • Maulaz, A.B.1    Bezerra, D.C.2    Michel, P.3    Bogousslavsky, J.4
  • 12
    • 33750924102 scopus 로고    scopus 로고
    • A systematic review and meta-analysis on the hazards of discontinuing or not adhering to aspirin among 50,279 patients at risk for coronary artery disease
    • G.G. Biondi-Zoccai, M. Lotrionte, P. Agostoni, A. Abbate, M. Fusaro, and F. Burzotta A systematic review and meta-analysis on the hazards of discontinuing or not adhering to aspirin among 50,279 patients at risk for coronary artery disease Eur Heart J 27 2006 2667 2674
    • (2006) Eur Heart J , vol.27 , pp. 2667-2674
    • Biondi-Zoccai, G.G.1    Lotrionte, M.2    Agostoni, P.3    Abbate, A.4    Fusaro, M.5    Burzotta, F.6
  • 13
    • 79960676489 scopus 로고    scopus 로고
    • Discontinuation of low dose aspirin and risk of myocardial infarction: Case-control study in UK primary care
    • 10.1136/bmj.d4094
    • L.A. Rodríguez, L. Cea-Soriano, E. Martín-Merino, and S. Johansson Discontinuation of low dose aspirin and risk of myocardial infarction: case-control study in UK primary care BMJ 343 2011 Jul 19 d4094 10.1136/bmj.d4094
    • (2011) BMJ , vol.343 , pp. 4094
    • Rodríguez, L.A.1    Cea-Soriano, L.2    Martín-Merino, E.3    Johansson, S.4
  • 14
    • 0036829086 scopus 로고    scopus 로고
    • Do changes in visceral sensory function determine the development of dyspepsia during treatment with aspirin?
    • G. Holtmann, J. Gschossmann, L. Buenger, G. Gerken, and N.J. Talley Do changes in visceral sensory function determine the development of dyspepsia during treatment with aspirin? Gastroenterology 123 5 2002 Nov 1451 1458
    • (2002) Gastroenterology , vol.123 , Issue.5 , pp. 1451-1458
    • Holtmann, G.1    Gschossmann, J.2    Buenger, L.3    Gerken, G.4    Talley, N.J.5
  • 15
    • 79951656816 scopus 로고    scopus 로고
    • Aspirin: Old drug, new uses and challenges
    • N.D. Yeomans Aspirin: old drug, new uses and challenges J Gastroenterol Hepatol 26 3 2011 Mar 426 431
    • (2011) J Gastroenterol Hepatol , vol.26 , Issue.3 , pp. 426-431
    • Yeomans, N.D.1
  • 16
    • 0014765042 scopus 로고
    • Profile of gastric potential difference in man. Effects of aspirin, alcohol, bile, and endogenous acid
    • M.G. Geall, S.F. Phillips, and W.H.J. Summerskill Profile of gastric potential difference in man. Effects of aspirin, alcohol, bile, and endogenous acid Gastroenterology 58 1970 437 443
    • (1970) Gastroenterology , vol.58 , pp. 437-443
    • Geall, M.G.1    Phillips, S.F.2    Summerskill, W.H.J.3
  • 17
    • 0030912032 scopus 로고    scopus 로고
    • Inflammatory mediators in gastrointestinal defense and injury
    • J.L. Wallace, and B.C. Chin Inflammatory mediators in gastrointestinal defense and injury Proc Soc Exp Biol Med 214 1997 192 203
    • (1997) Proc Soc Exp Biol Med , vol.214 , pp. 192-203
    • Wallace, J.L.1    Chin, B.C.2
  • 18
    • 0028308080 scopus 로고
    • Markedly reduced intestinal toxicity of a diclofenac derivative
    • B.K. Reuter, G. Cirino, and J.L. Wallace Markedly reduced intestinal toxicity of a diclofenac derivative Life Sci 55 1994 PL1 PL8
    • (1994) Life Sci , vol.55
    • Reuter, B.K.1    Cirino, G.2    Wallace, J.L.3
  • 19
    • 12144290072 scopus 로고    scopus 로고
    • Clinical pharmacology of platelet, monocyte, and vascular cyclooxygenase inhibition by naproxen and low-dose aspirin in healthy subjects
    • M.L. Capone, S. Tacconelli, M.G. Sciulli, M. Grana, E. Ricciotti, and P. Minuz Clinical pharmacology of platelet, monocyte, and vascular cyclooxygenase inhibition by naproxen and low-dose aspirin in healthy subjects Circulation 109 2004 Mar 30 1468 1471
    • (2004) Circulation , vol.109 , pp. 1468-1471
    • Capone, M.L.1    Tacconelli, S.2    Sciulli, M.G.3    Grana, M.4    Ricciotti, E.5    Minuz, P.6
  • 21
    • 4143107932 scopus 로고    scopus 로고
    • Cyclooxygenase isozymes: The biology of prostaglandin synthesis and inhibition
    • D.L. Simmons, R.M. Botting, and T. Hla Cyclooxygenase isozymes: the biology of prostaglandin synthesis and inhibition Pharmacol Rev 56 2004 387 437
    • (2004) Pharmacol Rev , vol.56 , pp. 387-437
    • Simmons, D.L.1    Botting, R.M.2    Hla, T.3
  • 23
    • 0034638656 scopus 로고    scopus 로고
    • Risk of gastrointestinal haemorrhage with long term use of aspirin: Meta-analysis
    • S. Derry, and Y.K. Loke Risk of gastrointestinal haemorrhage with long term use of aspirin: meta-analysis BMJ 321 2000 1183 1187
    • (2000) BMJ , vol.321 , pp. 1183-1187
    • Derry, S.1    Loke, Y.K.2
  • 25
    • 0030599533 scopus 로고    scopus 로고
    • Risk of aspirin-associated major upper-gastrointestinal bleeding with enteric-coated or buffered product
    • J.P. Kelly, D.W. Kaufman, J.M. Jurgelon, J. Sheehan, R.S. Koff, and S. Shapiro Risk of aspirin-associated major upper-gastrointestinal bleeding with enteric-coated or buffered product Lancet 348 9039 1996 Nov 23 1413 1416
    • (1996) Lancet , vol.348 , Issue.9039 , pp. 1413-1416
    • Kelly, J.P.1    Kaufman, D.W.2    Jurgelon, J.M.3    Sheehan, J.4    Koff, R.S.5    Shapiro, S.6
  • 26
    • 0035187293 scopus 로고    scopus 로고
    • Gastro-duodenal mucosal changes associated with low-dose aspirin therapy: A prospective, endoscopic study
    • A. Chowdhury, G. Ganguly, D. Chowdhury, A. Santra, J.D. Gupta, and T. Roy Gastro-duodenal mucosal changes associated with low-dose aspirin therapy: a prospective, endoscopic study Indian J Gastroenterol 20 2001 227 229
    • (2001) Indian J Gastroenterol , vol.20 , pp. 227-229
    • Chowdhury, A.1    Ganguly, G.2    Chowdhury, D.3    Santra, A.4    Gupta, J.D.5    Roy, T.6
  • 27
    • 0035512676 scopus 로고    scopus 로고
    • Association between aspirin and upper gastrointestinal complications: Systematic review of epidemiologic studies
    • L.A. Garcia Rodriguez, S. Hernandez-Diaz, and F.J. de Abajo Association between aspirin and upper gastrointestinal complications: systematic review of epidemiologic studies Br J Clin Pharmacol 52 2001 563 571
    • (2001) Br J Clin Pharmacol , vol.52 , pp. 563-571
    • Garcia Rodriguez, L.A.1    Hernandez-Diaz, S.2    De Abajo, F.J.3
  • 29
    • 3242706202 scopus 로고    scopus 로고
    • The effects of aspirin on gastric mucosal integrity, surface hydrophobicity, and prostaglandin metabolism in cyclooxygenase knockout mice
    • R.L. Darling, J.J. Romero, E.J. Dial, J.K. Akunda, R. Langenbach, and L.M. Lichtenberger The effects of aspirin on gastric mucosal integrity, surface hydrophobicity, and prostaglandin metabolism in cyclooxygenase knockout mice Gastroenterology 127 2004 94 104
    • (2004) Gastroenterology , vol.127 , pp. 94-104
    • Darling, R.L.1    Romero, J.J.2    Dial, E.J.3    Akunda, J.K.4    Langenbach, R.5    Lichtenberger, L.M.6
  • 30
    • 0021972799 scopus 로고
    • Effect of 16,16-dimethyl prostaglandin E2 on the surface hydrophobicity of aspirin-treated canine gastric mucosa
    • L.M. Lichtenberger, J.E. Richards, and B.A. Hills Effect of 16,16-dimethyl prostaglandin E2 on the surface hydrophobicity of aspirin-treated canine gastric mucosa Gastroenterology 88 1985 308 314
    • (1985) Gastroenterology , vol.88 , pp. 308-314
    • Lichtenberger, L.M.1    Richards, J.E.2    Hills, B.A.3
  • 31
    • 34248352504 scopus 로고    scopus 로고
    • Aspirin dose for the prevention of cardiovascular disease: A systematic review
    • C.L. Campbell, S. Smyth, G. Montalescot, and S.R. Steinhubl Aspirin dose for the prevention of cardiovascular disease: a systematic review JAMA 297 2007 2018 2024
    • (2007) JAMA , vol.297 , pp. 2018-2024
    • Campbell, C.L.1    Smyth, S.2    Montalescot, G.3    Steinhubl, S.R.4
  • 32
    • 0019954651 scopus 로고
    • Mechanism of aspirin injury to human gastroduodenal mucosa
    • M.M. Cohen, and W.C. MacDonald Mechanism of aspirin injury to human gastroduodenal mucosa Prostaglandins Leukot Med 9 1982 241 255
    • (1982) Prostaglandins Leukot Med , vol.9 , pp. 241-255
    • Cohen, M.M.1    MacDonald, W.C.2
  • 35
    • 0026458334 scopus 로고
    • Gastric changes in coronary-operated patients with low-dose aspirin
    • M. Leivonen, P. Sipponen, and E. Kivilaakso Gastric changes in coronary-operated patients with low-dose aspirin Scand J Gastroenterol 27 1992 912 916
    • (1992) Scand J Gastroenterol , vol.27 , pp. 912-916
    • Leivonen, M.1    Sipponen, P.2    Kivilaakso, E.3
  • 37
    • 34548266239 scopus 로고    scopus 로고
    • How to advise aspirin use in patients who need NSAIDs
    • F. Sopeña, and A. Lanas How to advise aspirin use in patients who need NSAIDs Curr Pharm Des 13 2007 2248 2260
    • (2007) Curr Pharm des , vol.13 , pp. 2248-2260
    • Sopeña, F.1    Lanas, A.2
  • 41
    • 0029002627 scopus 로고
    • Protective effect of omeprazol against low dose acetylsalicylic acid. Endoscopic controlled double-blind study in healthy subjects
    • B. Simon, H. Elsner, and P. Muller Protective effect of omeprazol against low dose acetylsalicylic acid. Endoscopic controlled double-blind study in healthy subjects Arzneimittelforshung 45 1995 701 703
    • (1995) Arzneimittelforshung , vol.45 , pp. 701-703
    • Simon, B.1    Elsner, H.2    Muller, P.3
  • 42
    • 0030796880 scopus 로고    scopus 로고
    • Studies on protective effect of lansoprazole on human gastric mucosa against low-dose acetylsalicylic. An endoscopic controlled double-blind study
    • P. Muller, W. Fuchs, and B. Simon Studies on protective effect of lansoprazole on human gastric mucosa against low-dose acetylsalicylic. An endoscopic controlled double-blind study Arzneimittelforshung 47 1997 758 760
    • (1997) Arzneimittelforshung , vol.47 , pp. 758-760
    • Muller, P.1    Fuchs, W.2    Simon, B.3
  • 44
    • 4143087071 scopus 로고    scopus 로고
    • Ulcer formation with low-dose enteric-coated aspirin and the effect of COX-2 selective inhibition: A double-blind trial
    • L. Laine, E.S. Maller, C. Yu, H. Quan, and T. Simon Ulcer formation with low-dose enteric-coated aspirin and the effect of COX-2 selective inhibition: a double-blind trial Gastroenterology 127 2 2004 Aug 395 402
    • (2004) Gastroenterology , vol.127 , Issue.2 , pp. 395-402
    • Laine, L.1    Maller, E.S.2    Yu, C.3    Quan, H.4    Simon, T.5
  • 45
    • 0037021982 scopus 로고    scopus 로고
    • Eradication of Helicobacter pylori and risk of peptic ulcers in patients starting long-term treatment with non-steroidal anti-inflammatory drugs: A randomised trial
    • F.K. Chan, K.F. To, J.C. Wu, M.Y. Yung, W.K. Leung, and T. Kwok Eradication of Helicobacter pylori and risk of peptic ulcers in patients starting long-term treatment with non-steroidal anti-inflammatory drugs: a randomised trial Lancet 359 9300 2002 Jan 5 9 13
    • (2002) Lancet , vol.359 , Issue.9300 , pp. 9-13
    • Chan, F.K.1    To, K.F.2    Wu, J.C.3    Yung, M.Y.4    Leung, W.K.5    Kwok, T.6
  • 46
    • 70349667386 scopus 로고    scopus 로고
    • Evidence for endoscopic ulcers as meaningful surrogate endpoint for clinically significant upper gastrointestinal harm
    • A. Moore, I. Bjarnason, B. Cryer, L. Garcia-Rodriguez, L. Goldkind, and A. Lanas Evidence for endoscopic ulcers as meaningful surrogate endpoint for clinically significant upper gastrointestinal harm Clin Gastroenterol Hepatol 7 11 2009 Nov 1156 1163
    • (2009) Clin Gastroenterol Hepatol , vol.7 , Issue.11 , pp. 1156-1163
    • Moore, A.1    Bjarnason, I.2    Cryer, B.3    Garcia-Rodriguez, L.4    Goldkind, L.5    Lanas, A.6
  • 47
    • 14644408717 scopus 로고    scopus 로고
    • Nonsteroidal antiinflammatory drugs and the small intestine
    • P.J. Fortun, and C.J. Hawkey Nonsteroidal antiinflammatory drugs and the small intestine Curr Opin Gastroenterol 21 2005 169 175
    • (2005) Curr Opin Gastroenterol , vol.21 , pp. 169-175
    • Fortun, P.J.1    Hawkey, C.J.2
  • 48
    • 38849084090 scopus 로고    scopus 로고
    • Faecal blood loss with aspirin, nonsteroidal anti-inflammatory drugs and cyclo-oxygenase-2 selective inhibitors: Systematic review of randomized trials using autologous chromium-labelled erythrocytes
    • R.A. Moore, S. Derry, and H.J. McQuay Faecal blood loss with aspirin, nonsteroidal anti-inflammatory drugs and cyclo-oxygenase-2 selective inhibitors: systematic review of randomized trials using autologous chromium-labelled erythrocytes Arthritis Res Ther 10 2008 R7
    • (2008) Arthritis Res Ther , vol.10 , pp. 7
    • Moore, R.A.1    Derry, S.2    McQuay, H.J.3
  • 49
    • 67349099080 scopus 로고    scopus 로고
    • Low-dose aspirin affects the small bowel mucosa: Results of a pilot study with a multidimensional assessment
    • E. Smecuol, M.I. Pinto Sanchez, A. Suarez, J.E. Argonz, E. Sugai, and H. Vazquez Low-dose aspirin affects the small bowel mucosa: results of a pilot study with a multidimensional assessment Clin Gastroenterol Hepatol 7 5 2009 May 524 529
    • (2009) Clin Gastroenterol Hepatol , vol.7 , Issue.5 , pp. 524-529
    • Smecuol, E.1    Pinto Sanchez, M.I.2    Suarez, A.3    Argonz, J.E.4    Sugai, E.5    Vazquez, H.6
  • 50
    • 33749536913 scopus 로고    scopus 로고
    • Cardioprotective aspirin users and their excess risk of upper gastrointestinal complications
    • S. Hernández-Díaz, and L.A. García Rodríguez Cardioprotective aspirin users and their excess risk of upper gastrointestinal complications BMC Med 4 2006 Sep 20 22
    • (2006) BMC Med , vol.4 , pp. 22
    • Hernández-Díaz, S.1    García Rodríguez, L.A.2
  • 51
    • 0034699601 scopus 로고    scopus 로고
    • Nitrovasodilators, low-dose aspirin, other nonsteroidal antiinflammatory drugs, and the risk of upper gastrointestinal bleeding
    • A. Lanas, E. Bajador, P. Serrano, J. Fuentes, S. Carreño, and J. Guardia Nitrovasodilators, low-dose aspirin, other nonsteroidal antiinflammatory drugs, and the risk of upper gastrointestinal bleeding N Engl J Med 343 2000 834 839
    • (2000) N Engl J Med , vol.343 , pp. 834-839
    • Lanas, A.1    Bajador, E.2    Serrano, P.3    Fuentes, J.4    Carreño, S.5    Guardia, J.6
  • 52
    • 0036113540 scopus 로고    scopus 로고
    • Helicobacter pylori increases the risk of upper gastrointestinal bleeding in patients taking low-dose aspirin
    • A. Lanas, J. Fuentes, R. Benito, P. Serrano, E. Bajador, and R. Sainz Helicobacter pylori increases the risk of upper gastrointestinal bleeding in patients taking low-dose aspirin Aliment Pharmacol Ther 16 2002 779 786
    • (2002) Aliment Pharmacol Ther , vol.16 , pp. 779-786
    • Lanas, A.1    Fuentes, J.2    Benito, R.3    Serrano, P.4    Bajador, E.5    Sainz, R.6
  • 53
    • 80052026195 scopus 로고    scopus 로고
    • Low doses of acetylsalicylic acid increase risk of gastrointestinal bleeding in a meta-analysis
    • A. Lanas, P. Wu, J. Medin, and E.J. Mills Low doses of acetylsalicylic acid increase risk of gastrointestinal bleeding in a meta-analysis Clin Gastroenterol Hepatol 9 9 2011 Sep 762 768
    • (2011) Clin Gastroenterol Hepatol , vol.9 , Issue.9 , pp. 762-768
    • Lanas, A.1    Wu, P.2    Medin, J.3    Mills, E.J.4
  • 54
  • 55
    • 0036828646 scopus 로고    scopus 로고
    • Risk of upper gastrointestinal bleeding in patients taking low-dose aspirin for the prevention of cardiovascular diseases
    • P. Serrano, A. Lanas, M.T. Arroyo, and I.J. Ferreira Risk of upper gastrointestinal bleeding in patients taking low-dose aspirin for the prevention of cardiovascular diseases Aliment Pharmacol Ther 16 2002 1945 1951
    • (2002) Aliment Pharmacol Ther , vol.16 , pp. 1945-1951
    • Serrano, P.1    Lanas, A.2    Arroyo, M.T.3    Ferreira, I.J.4
  • 56
    • 25444437492 scopus 로고    scopus 로고
    • Bleeding complications related to aspirin dose
    • L. Laine, and K. McQuaid Bleeding complications related to aspirin dose Am J Cardiol 96 7 2005 Oct 1 1035 1036
    • (2005) Am J Cardiol , vol.96 , Issue.7 , pp. 1035-1036
    • Laine, L.1    McQuaid, K.2
  • 57
    • 77956290748 scopus 로고    scopus 로고
    • Dose comparisons of clopidogrel and aspirin in acute coronary syndromes
    • Current-Oasis 7 Investigators
    • CURRENT-OASIS 7 Investigators, S.R. Mehta, J.P. Bassand, S. Chrolavicius, R. Diaz, J.W. Eikelboom, and K.A. Fox Dose comparisons of clopidogrel and aspirin in acute coronary syndromes N Engl J Med 363 10 2010 Sep 2 930 942
    • (2010) N Engl J Med , vol.363 , Issue.10 , pp. 930-942
    • Mehta, S.R.1    Bassand, J.P.2    Chrolavicius, S.3    Diaz, R.4    Eikelboom, J.W.5    Fox, K.A.6
  • 58
    • 50849128455 scopus 로고    scopus 로고
    • Clinical trial: The incidence and early mortality after peptic ulcer perforation, and the use of low-dose aspirin and nonsteroidal anti-inflammatory drugs
    • A.S. Taha, W.J. Angerson, R. Prasad, C. McCloskey, D. Gilmour, and C.G. Morran Clinical trial: the incidence and early mortality after peptic ulcer perforation, and the use of low-dose aspirin and nonsteroidal anti-inflammatory drugs Aliment Pharmacol Ther 28 7 2008 Oct 1 878 885
    • (2008) Aliment Pharmacol Ther , vol.28 , Issue.7 , pp. 878-885
    • Taha, A.S.1    Angerson, W.J.2    Prasad, R.3    McCloskey, C.4    Gilmour, D.5    Morran, C.G.6
  • 59
    • 0018826501 scopus 로고
    • Comparison of the effects of regular and enteric-coated aspirin on gastroduodenal mucosa of man
    • J.W. Hoftiezer, G.R. Silvoso, M. Burks, and K.J. Ivey Comparison of the effects of regular and enteric-coated aspirin on gastroduodenal mucosa of man Lancet 2 8195 pt 1 1980 Sep 20 609 612
    • (1980) Lancet , vol.2 , Issue.8195 PART 1 , pp. 609-612
    • Hoftiezer, J.W.1    Silvoso, G.R.2    Burks, M.3    Ivey, K.J.4
  • 61
    • 0026674243 scopus 로고
    • Objective evidence of aspirin use in both ulcer and non-ulcer upper and lower gastrointestinal bleeding
    • A. Lanas, M.C. Sekar, and B.I. Hirschowitz Objective evidence of aspirin use in both ulcer and non-ulcer upper and lower gastrointestinal bleeding Gastroenterology 103 1992 862 869
    • (1992) Gastroenterology , vol.103 , pp. 862-869
    • Lanas, A.1    Sekar, M.C.2    Hirschowitz, B.I.3
  • 62
    • 0021959535 scopus 로고
    • Use of anti-inflammatory drugs by patients admitted with small or large bowel perforations and haemorrhage
    • M.J. Langman, L. Morgan, and A. Worrall Use of anti-inflammatory drugs by patients admitted with small or large bowel perforations and haemorrhage Br Med J (Clin Res Ed) 290 6465 1985 Feb 2 347 349
    • (1985) Br Med J (Clin Res Ed) , vol.290 , Issue.6465 , pp. 347-349
    • Langman, M.J.1    Morgan, L.2    Worrall, A.3
  • 63
    • 0030962702 scopus 로고    scopus 로고
    • Nonsteroidal antiinflammatory drugs are associated with both upper and lower gastrointestinal bleeding
    • C.M. Wilcox, L.N. Alexander, G.A. Cotsonis, and W.S. Clark Nonsteroidal antiinflammatory drugs are associated with both upper and lower gastrointestinal bleeding Dig Dis Sci 42 1997 990 997
    • (1997) Dig Dis Sci , vol.42 , pp. 990-997
    • Wilcox, C.M.1    Alexander, L.N.2    Cotsonis, G.A.3    Clark, W.S.4
  • 64
    • 0031056625 scopus 로고    scopus 로고
    • Evidence of aspirin use in both upper and lower gastrointestinal perforation
    • A. Lanas, P. Serrano, E. Bajador, F. Esteva, R. Benito, and R. Sainz Evidence of aspirin use in both upper and lower gastrointestinal perforation Gastroenterology 112 1997 683 689
    • (1997) Gastroenterology , vol.112 , pp. 683-689
    • Lanas, A.1    Serrano, P.2    Bajador, E.3    Esteva, F.4    Benito, R.5    Sainz, R.6
  • 65
    • 25644452810 scopus 로고    scopus 로고
    • A nationwide study of mortality associated with hospital admission due to severe gastrointestinal events and those associated with nonsteroidal antiinflammatory drug use
    • A. Lanas, M.A. Perez-Aisa, F. Feu, J. Ponce, E. Saperas, and S. Santolaria A nationwide study of mortality associated with hospital admission due to severe gastrointestinal events and those associated with nonsteroidal antiinflammatory drug use Am J Gastroenterol 100 2005 1685 1693
    • (2005) Am J Gastroenterol , vol.100 , pp. 1685-1693
    • Lanas, A.1    Perez-Aisa, M.A.2    Feu, F.3    Ponce, J.4    Saperas, E.5    Santolaria, S.6
  • 66
    • 79955455089 scopus 로고    scopus 로고
    • Use of aspirin or nonsteroidal anti-inflammatory drugs increases risk for diverticulitis and diverticular bleeding
    • [Epub 2011 Feb 12]
    • L.L. Strate, Y.L. Liu, E.S. Huang, E.L. Giovannucci, and A.T. Chan Use of aspirin or nonsteroidal anti-inflammatory drugs increases risk for diverticulitis and diverticular bleeding Gastroenterology 140 5 2011 May 1427 1433 [Epub 2011 Feb 12]
    • (2011) Gastroenterology , vol.140 , Issue.5 , pp. 1427-1433
    • Strate, L.L.1    Liu, Y.L.2    Huang, E.S.3    Giovannucci, E.L.4    Chan, A.T.5
  • 67
    • 77958510011 scopus 로고    scopus 로고
    • Long-term use of aspirin and the risk of gastrointestinal bleeding in a prospective, population-based cohort
    • E. Huang, L.L. Strate, W. Ho, S.S. Lee, and A.T. Chan Long-term use of aspirin and the risk of gastrointestinal bleeding in a prospective, population-based cohort Gastroenterology 138 Suppl. 1 2010 475e
    • (2010) Gastroenterology , vol.138 , Issue.SUPPL. 1
    • Huang, E.1    Strate, L.L.2    Ho, W.3    Lee, S.S.4    Chan, A.T.5
  • 68
    • 73849146970 scopus 로고    scopus 로고
    • HCUP Statistical Brief #65 Agency for Healthcare Research and Quality Rockville, MD
    • Y. Zhao, and W. Encinosa Hospitalizations for gastrointestinal bleeding 1998 and 2006 HCUP Statistical Brief #65 December 2008 Agency for Healthcare Research and Quality Rockville, MD http://www.hcup-us.ahr.gov/reports/ statbriefs/sb65.pdf
    • (2008) Hospitalizations for Gastrointestinal Bleeding 1998 and 2006
    • Zhao, Y.1    Encinosa, W.2
  • 70
    • 55349127823 scopus 로고    scopus 로고
    • First International Working Party on gastrointestinal and cardiovascular effects of nonsteroidal anti-inflammatory drugs and anti-platelet agents. Management of patients on nonsteroidal anti-inflammatory drugs: A clinical practice recommendation from the First International Working Party on gastrointestinal and cardiovascular effects of nonsteroidal anti-inflammatory drugs and anti-platelet agents
    • F.K. Chan, N.S. Abraham, J.M. Scheiman, and L. Laine First International Working Party on gastrointestinal and cardiovascular effects of nonsteroidal anti-inflammatory drugs and anti-platelet agents. Management of patients on nonsteroidal anti-inflammatory drugs: a clinical practice recommendation from the First International Working Party on gastrointestinal and cardiovascular effects of nonsteroidal anti-inflammatory drugs and anti-platelet agents Am J Gastroenterol 103 2008 2908 2918
    • (2008) Am J Gastroenterol , vol.103 , pp. 2908-2918
    • Chan, F.K.1    Abraham, N.S.2    Scheiman, J.M.3    Laine, L.4
  • 71
    • 12944262286 scopus 로고    scopus 로고
    • Clinical trends in ulcer diagnosis in a population with high prevalence of Helicobacter pylori infection
    • M.A. Pérez-Aisa, D. Del Pino, M. Siles, and A. Lanas Clinical trends in ulcer diagnosis in a population with high prevalence of Helicobacter pylori infection Aliment Pharmacol Ther 21 2005 65 67
    • (2005) Aliment Pharmacol Ther , vol.21 , pp. 65-67
    • Pérez-Aisa, M.A.1    Del Pino, D.2    Siles, M.3    Lanas, A.4
  • 72
    • 65549161327 scopus 로고    scopus 로고
    • The role of proton pump inhibitors in the management of upper gastrointestinal bleeding
    • G.I. Leontiadis, and C.W. Howden The role of proton pump inhibitors in the management of upper gastrointestinal bleeding Gastroenterol Clin North Am 38 2009 199 213
    • (2009) Gastroenterol Clin North Am , vol.38 , pp. 199-213
    • Leontiadis, G.I.1    Howden, C.W.2
  • 73
    • 62949245938 scopus 로고    scopus 로고
    • Endoscopic hemostasis in peptic ulcer bleeding for patients with high-risk lesions: A series of meta-analyses
    • A.N. Barkun, M. Martel, Y. Toubouti, E. Rahme, and M. Bardou Endoscopic hemostasis in peptic ulcer bleeding for patients with high-risk lesions: a series of meta-analyses Gastrointest Endosc 69 2009 786 799
    • (2009) Gastrointest Endosc , vol.69 , pp. 786-799
    • Barkun, A.N.1    Martel, M.2    Toubouti, Y.3    Rahme, E.4    Bardou, M.5
  • 74
    • 73849149849 scopus 로고    scopus 로고
    • Editorial: Upper GI bleeding-associated mortality: Challenges to improving a resistant outcome
    • A. Lanas Editorial: upper GI bleeding-associated mortality: challenges to improving a resistant outcome Am J Gastroenterol 105 1 2010 Jan 90 92
    • (2010) Am J Gastroenterol , vol.105 , Issue.1 , pp. 90-92
    • Lanas, A.1
  • 76
    • 0037373349 scopus 로고    scopus 로고
    • Gastrointestinal safety of NO-aspirin (NCX 4016) in healthy human volunteers: A proof of concept endoscopic study
    • S. Fiorucci, L. Santucci, P. Gresele, R.M. Faccino, P. Del Soldato, and A. Morelli Gastrointestinal safety of NO-aspirin (NCX 4016) in healthy human volunteers: a proof of concept endoscopic study Gastroenterology 124 2003 600 607
    • (2003) Gastroenterology , vol.124 , pp. 600-607
    • Fiorucci, S.1    Santucci, L.2    Gresele, P.3    Faccino, R.M.4    Del Soldato, P.5    Morelli, A.6
  • 77
    • 0029147850 scopus 로고
    • In vitro recovery of canine gastric mucosal surface hydrophobicity and potential difference after aspirin damage
    • P.J. Goddard, and L.M. Lichtenberger In vitro recovery of canine gastric mucosal surface hydrophobicity and potential difference after aspirin damage Dig Dis Sci 40 1995 1357 1359
    • (1995) Dig Dis Sci , vol.40 , pp. 1357-1359
    • Goddard, P.J.1    Lichtenberger, L.M.2
  • 78
    • 79751528169 scopus 로고    scopus 로고
    • Low-dose aspirin-induced ulceration is attenuated by aspirin- phosphatidylcholine: A randomized clinical trial
    • B. Cryer, D.L. Bhatt, F.L. Lanza, J.F. Dong, L.M. Lichtenberger, and U.K. Marathi Low-dose aspirin-induced ulceration is attenuated by aspirin-phosphatidylcholine: a randomized clinical trial Am J Gastroenterol 106 2011 272 277
    • (2011) Am J Gastroenterol , vol.106 , pp. 272-277
    • Cryer, B.1    Bhatt, D.L.2    Lanza, F.L.3    Dong, J.F.4    Lichtenberger, L.M.5    Marathi, U.K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.