Acquired epidermodysplasia verruciformis due to multiple and unusual HPV infection among vertically-infected, HIV-positive adolescents in Zimbabwe

Clinical Infectious Diseases

Volumn 54, Issue 10, 2012, Pages

  Lowe, S M ^a   Katsidzira, L ^a   Meys, R ^b   Sterling, J C ^c   De Koning, M ^d   Quint, W ^d   Nathoo, K ^a   Munyati, S ^a   Ndhlovu, C E ^a   Salisbury, J R ^e   Bunker, C B ^b   Corbett, E L ^f,g   Miller, R F ^b,g   Ferrand, R A ^a,g  

^a UNIVERSITY OF ZIMBABWE   (Zimbabwe)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d DDL DIAGNOSTIC LABORATORY   (Netherlands)

^e KING'S COLLEGE LONDON   (United Kingdom)

^f UNIVERSITY OF MALAWI   (United Kingdom)

^g LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; LAMIVUDINE; NEVIRAPINE; STAVUDINE;

ADOLESCENT; ARTICLE; CASE REPORT; CONDYLOMA ACUMINATUM; DISEASE COURSE; EPIDERMODYSPLASIA VERRUCIFORMIS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN PAPILLOMAVIRUS TYPE 1; HUMAN PAPILLOMAVIRUS TYPE 16; HUMAN PAPILLOMAVIRUS TYPE 19; HUMAN PAPILLOMAVIRUS TYPE 2; HUMAN PAPILLOMAVIRUS TYPE 52; HUMAN PAPILLOMAVIRUS TYPE 6; HUMAN TISSUE; IMMUNE DEFICIENCY; MALE; NONHUMAN; PRIORITY JOURNAL; SKIN BIOPSY; SUN EXPOSURE; TREATMENT RESPONSE; VERTICAL TRANSMISSION; VIRUS IDENTIFICATION; VIRUS TYPING; WART VIRUS; ZIMBABWE;

ADOLESCENT; BIOPSY; CHILD; DNA FINGERPRINTING; EPIDERMODYSPLASIA VERRUCIFORMIS; GENOTYPE; HISTOCYTOCHEMISTRY; HIV INFECTIONS; HUMANS; INFECTIOUS DISEASE TRANSMISSION, VERTICAL; MALE; MICROSCOPY; PAPILLOMAVIRIDAE; SKIN; ZIMBABWE;

EID: 84860228526     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/cid/cis118     Document Type: Article

References (22)

1. Gul U, Kilic A, Gonul M, Cakmak SK, Bayis SS. Clinical aspects of epidermodysplasia verruciformis and review of the literature. Int J Dermatol 2007; 46:1069-72.
2. Jablonska S, Orth G, Jarzabek-Chorzelska M, et al. Epidermodysplasia verruciformis versus disseminated verrucae planae: is epidermodysplasia verruciformis a generalized infection with wart virus? J Invest Dermatol 1979; 72:114-19.
3. Ramoz N, Taieb A, Rueda LA, et al. Evidence for a nonallelic heterogeneity of epidermodysplasia verruciformis with two susceptibility loci mapped to chromosome regions 2p21-p24 and 17q25. J Invest Dermatol 2000; 114:1148-53.
4. Bonamigo R, Maldonado G, Londero RM, Cartell A. Epidermodysplasia verruciformis-like disorder in a teenager with HIV and HCV infections. Pediatr Dermatol 2007; 24:456-7.
5. Barzegar C, Paul C, Saiag P, et al. Epidermodysplasia verruciformis-like eruption complicating human immunodeficiency virus infection. Br J Dermatol 1998; 139:122-7.
6. Davison SC, Francis N, McLean K, Bunker CB. Epidermodysplasia verruciformis-like eruption associated with HIV infection. Clin Exp Dermatol 2004; 29:311-12.
7. Haas N, Fuchs PG, Hermes B, Henz BM. Remission of epidermodysplasia verruciformis-like skin eruption after highly active antiretroviral therapy in a human immunodeficiency virus-positive patient. Br J Dermatol 2001; 145:669-70.
8. Carre D, Dompmartin A, Verdon R, et al. Epidermodysplasia verruciformis in a patient with HIV infection: no response to highly active antiretroviral therapy. Int J Dermatol 2003; 42:296-300.
9. Jacobelli S, Laude H, Carlotti A, et al. Epidermodysplasia verruciformis in human immunodeficiency virus-infected patients: a marker of human papillomavirus-related disorders not affected by antiretroviral therapy. Arch Dermatol 2011; 147:590-6.
10. Lee KC, Risser J, Bercovitch L. What is the evidence for effective treatments of acquired epidermodysplasia verruciformis in HIVinfected patients? Arch Dermatol 2010; 146:903-5.
11. Lowe S, Ferrand RA, Morris-Jones R, et al. Skin disease among human immunodeficiency virus-infected adolescents in Zimbabwe: a strong indicator of underlying HIV infection. Pediatr Infect Dis J 2010; 29: 346-51.
12. Berkhout RJ, Tieben LM, Smits HL, Bavinck JN, Vermeer BJ, ter Schegget J. Nested PCR approach for detection and typing of epidermodysplasia verruciformis-associated human papillomavirus types in cutaneous cancers from renal transplant recipients. J Clin Microbiol 1995; 33:690-5.
13. Harwood CA, Spink PJ, Surentheran T, et al. Degenerate and nested PCR: a highly sensitive and specific method for detection of human papillomavirus infection in cutaneous warts. J Clin Microbiol 1999; 37:3545-55.
14. de Koning M, Quint W, Struijk L, et al. Evaluation of a novel highly sensitive, broad-spectrum PCR-reverse hybridization assay for detection and identification of beta-papillomavirus DNA. J Clin Microbiol 2006; 44:1792-800.
15. de Koning MN, ter Schegget J, Eekhof JA, et al. Evaluation of a novel broad-spectrum PCR-multiplex genotyping assay for identification of cutaneous wart-associated human papillomavirus types. J Clin Microbiol 2010; 48:1706-11.
16. Levi JE, Kleter B, Quint WG, et al. High prevalence of human papillomavirus (HPV) infections and high frequency of multiple HPV genotypes in human immunodeficiency virus-infected women in Brazil. J Clin Microbiol 2002; 40:3341-5.
17. Weissenborn SJ, Wieland U, Junk M, Pfister H. Quantification of betahuman papillomavirus DNA by real-time PCR. Nat Protoc 2010; 5:1-13.
18. Orth G. Host defenses against human papillomaviruses: lessons from epidermodysplasia verruciformis. Curr Top Microbiol Immunol 2008; 321:59-83.
19. Hohenstein E, Rady PL, Hergersberg M, et al. Epidermodysplasia verruciformis in a HIV-positive patient homozygous for the c917A->T polymorphism in the TMC8/EVER2 gene. Dermatology 2009; 218: 114-18.
20. Astori G, Lavergne D, Benton C, et al. Human papillomaviruses are commonly found in normal skin of immunocompetent hosts. J Invest Dermatol 1998; 110:752-5.
21. Moore RL, de Schaetzen V, Joseph M, et al. Acquired epidermodysplasia verruciformis syndrome in HIV-infected pediatric patients: prospective treatment trial with topical glycolic acid and human papillomavirus genotype characterization. Arch Dermatol 2012; 148:128-30.
22. Sehgal VN, Luthra A, Bajaj P. Epidermodysplasia verruciformis: 14 members of a pedigree with an intriguing squamous cell carcinoma transformation. Int J Dermatol 2002; 41:500-3.