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Volumn 57, Issue 5, 2012, Pages 460-468

The optimal dose of recombinant human osteogenic protein-1 enhances differentiation of mouse osteoblast-like cells: An in vitro study

Author keywords

Cell differentiation; Cell proliferation; OP 1

Indexed keywords

ALKALINE PHOSPHATASE; ALKALINE PHOSPHATASE 2, MOUSE; BONE MORPHOGENETIC PROTEIN; CARRIER PROTEIN; COLLAGEN; NOGGIN PROTEIN; OSTEOCALCIN; OSTEOGENIC PROTEIN 1 PUTTY, RECOMBINANT HUMAN; PRIMER DNA; RUNX2 PROTEIN, MOUSE; TRANSCRIPTION FACTOR RUNX2;

EID: 84860226199     PISSN: 00039969     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.archoralbio.2011.10.008     Document Type: Article
Times cited : (25)

References (40)
  • 1
    • 0031909665 scopus 로고    scopus 로고
    • Role of morphogenetic proteins in skeletal tissue engineering and regeneration
    • A.H. Reddi Role of morphogenetic proteins in skeletal tissue engineering and regeneration Nat Biotechnol 16 3 1998 247 252
    • (1998) Nat Biotechnol , vol.16 , Issue.3 , pp. 247-252
    • Reddi, A.H.1
  • 2
    • 34250019537 scopus 로고
    • Bone: Formation by autoinduction
    • M.R. Urist Bone: formation by autoinduction Science 150 698 1965 893 899
    • (1965) Science , vol.150 , Issue.698 , pp. 893-899
    • Urist, M.R.1
  • 3
    • 0037102589 scopus 로고    scopus 로고
    • Overview of bone morphogenetic proteins
    • J.M. Wozney Overview of bone morphogenetic proteins Spine (Phila Pa 1976) 27 16 Suppl. 1 2002 S2 S8
    • (2002) Spine (Phila Pa 1976) , vol.27 , Issue.16 SUPPL. 1
    • Wozney, J.M.1
  • 4
    • 0031155082 scopus 로고    scopus 로고
    • Bone morphogenetic proteins: Background and implications for oral reconstruction A review
    • M.B. Lee Bone morphogenetic proteins: background and implications for oral reconstruction. A review J Clin Periodontol 24 6 1997 355 365 (Pubitemid 127731535)
    • (1997) Journal of Clinical Periodontology , vol.24 , Issue.6 , pp. 355-365
    • Lee, M.B.1
  • 5
    • 0034803019 scopus 로고    scopus 로고
    • Bone morphogenetic protein regulation of forkhead/winged helix transcription factor Foxc2 (Mfh1) in a murine mesodermal cell line C1 and in skeletal precursor cells
    • A. Nifuji, N. Miura, N. Kato, O. Kellermann, and M. Noda Bone morphogenetic protein regulation of forkhead/winged helix transcription factor Foxc2 (Mfh1) in a murine mesodermal cell line C1 and in skeletal precursor cells J Bone Miner Res 16 10 2001 1765 1771 (Pubitemid 32911481)
    • (2001) Journal of Bone and Mineral Research , vol.16 , Issue.10 , pp. 1765-1771
    • Nifuji, A.1    Miura, N.2    Kato, N.3    Kellermann, O.4    Noda, M.5
  • 6
    • 0026575663 scopus 로고
    • The BMP proteins in bone formation and repair
    • V. Rosen, and R.S. Thies The BMP proteins in bone formation and repair Trends Genet 8 3 1992 97 102
    • (1992) Trends Genet , vol.8 , Issue.3 , pp. 97-102
    • Rosen, V.1    Thies, R.S.2
  • 7
    • 16244411961 scopus 로고    scopus 로고
    • The ABCs of BMPs
    • quiz 53-44
    • S.D. Boden The ABCs of BMPs Orthop Nurs 24 1 2005 49 52 quiz 53-44
    • (2005) Orthop Nurs , vol.24 , Issue.1 , pp. 49-52
    • Boden, S.D.1
  • 8
    • 0345151815 scopus 로고    scopus 로고
    • Recombinant human bone morphogenetic protein-2 overcomes the inhibitory effect of ketorolac, a nonsteroidal anti-inflammatory drug (NSAID), on posterolateral lumbar intertransverse process spine fusion
    • discussion 2193-2184
    • G.J. Martin Jr., S.D. Boden, and L. Titus Recombinant human bone morphogenetic protein-2 overcomes the inhibitory effect of ketorolac, a nonsteroidal anti-inflammatory drug (NSAID), on posterolateral lumbar intertransverse process spine fusion Spine (Phila Pa 1976) 24 21 1999 2188 2193 discussion 2193-2184
    • (1999) Spine (Phila Pa 1976) , vol.24 , Issue.21 , pp. 2188-2193
    • Martin, Jr.G.J.1    Boden, S.D.2    Titus, L.3
  • 9
    • 3042856767 scopus 로고    scopus 로고
    • Development of a New Zealand white rabbit model of spinal pseudarthrosis repair and evaluation of the potential role of OP-1 to overcome pseudarthrosis
    • DOI 10.1097/01.BRS.0000129028.25671.96
    • J.N. Grauer, A.R. Vaccaro, M. Kato, B.K. Kwon, J.M. Beiner, and T.C. Patel Development of a New Zealand white rabbit model of spinal pseudarthrosis repair and evaluation of the potential role of OP-1 to overcome pseudarthrosis Spine (Phila Pa 1976) 29 13 2004 1405 1412 (Pubitemid 38879043)
    • (2004) Spine , vol.29 , Issue.13 , pp. 1405-1412
    • Grauer, J.N.1    Vaccaro, A.R.2    Kato, M.3    Kwon, B.K.4    Beiner, J.M.5    Patel, T.C.6    Hilibrand, A.S.7    Chiba, K.8    Albert, T.J.9
  • 10
    • 0033387455 scopus 로고    scopus 로고
    • Recombinant bone morphogenetic protein-7 as an intracorporal bone growth stimulator in unstable thoracolumbar burst fractures in humans: Preliminary results
    • DOI 10.1007/s005860050210
    • M. Laursen, K. Hoy, E.S. Hansen, J. Gelineck, F.B. Christensen, and C.E. Bunger Recombinant bone morphogenetic protein-7 as an intracorporal bone growth stimulator in unstable thoracolumbar burst fractures in humans: preliminary results Eur Spine J 8 6 1999 485 490 (Pubitemid 30080570)
    • (1999) European Spine Journal , vol.8 , Issue.6 , pp. 485-490
    • Laursen, M.1    Hoy, K.2    Hansen, E.S.3    Gelineck, J.4    Christensen, F.B.5    Bunger, C.E.6
  • 11
    • 0032728667 scopus 로고    scopus 로고
    • Osteogenic activity of OP-1 bone morphogenetic protein (BMP-7) in a human fibular defect
    • R.G. Geesink, N.H. Hoefnagels, and S.K. Bulstra Osteogenic activity of OP-1 bone morphogenetic protein (BMP-7) in a human fibular defect J Bone Joint Surg Br 81 4 1999 710 718
    • (1999) J Bone Joint Surg Br , vol.81 , Issue.4 , pp. 710-718
    • Geesink, R.G.1    Hoefnagels, N.H.2    Bulstra, S.K.3
  • 13
    • 0030885311 scopus 로고    scopus 로고
    • Osteogenic protein-1 and insulin-like growth factor I synergistically stimulate rat osteoblastic cell differentiation and proliferation
    • DOI 10.1210/en.138.10.4181
    • L.C. Yeh, M.L. Adamo, M.S. Olson, and J.C. Lee Osteogenic protein-1 and insulin-like growth factor I synergistically stimulate rat osteoblastic cell differentiation and proliferation Endocrinology 138 10 1997 4181 4190 (Pubitemid 27408459)
    • (1997) Endocrinology , vol.138 , Issue.10 , pp. 4181-4190
    • Yeh, L.-C.C.1    Adamo, M.L.2    Olson, M.S.3    Lee, J.C.4
  • 14
    • 0030056920 scopus 로고    scopus 로고
    • Human osteogenic protein-1 induces chondroblastic, osteoblastic, and/or adipocytic differentiation of clonal murine target cells
    • DOI 10.1006/excr.1996.0005
    • I. Asahina, T.K. Sampath, and P.V. Hauschka Human osteogenic protein-1 induces chondroblastic, osteoblastic, and/or adipocytic differentiation of clonal murine target cells Exp Cell Res 222 1 1996 38 47 (Pubitemid 26043710)
    • (1996) Experimental Cell Research , vol.222 , Issue.1 , pp. 38-47
    • Asahina, I.1    Sampath, T.K.2    Hauschka, P.V.3
  • 15
    • 0242443188 scopus 로고    scopus 로고
    • Effects of Osteogenic Protein-1 (OP-1, BMP-7) on Gene Expression in Cultured Medial Collateral Ligament Cells
    • DOI 10.1002/jcb.10666
    • A.D. Tsai, L.C. Yeh, and J.C. Lee Effects of osteogenic protein-1 (OP-1, BMP-7) on gene expression in cultured medial collateral ligament cells J Cell Biochem 90 4 2003 777 791 (Pubitemid 37392468)
    • (2003) Journal of Cellular Biochemistry , vol.90 , Issue.4 , pp. 777-791
    • Tsai, A.D.1    Yeh, L.-C.C.2    Lee, J.C.3
  • 16
    • 74949118565 scopus 로고    scopus 로고
    • The role of BMP-7 in chondrogenic and osteogenic differentiation of human bone marrow multipotent mesenchymal stromal cells in vitro
    • B. Shen, A. Wei, S. Whittaker, L.A. Williams, H. Tao, and D.D. Ma The role of BMP-7 in chondrogenic and osteogenic differentiation of human bone marrow multipotent mesenchymal stromal cells in vitro J Cell Biochem 109 2 2010 406 416
    • (2010) J Cell Biochem , vol.109 , Issue.2 , pp. 406-416
    • Shen, B.1    Wei, A.2    Whittaker, S.3    Williams, L.A.4    Tao, H.5    Ma, D.D.6
  • 17
    • 0033847399 scopus 로고    scopus 로고
    • Osteogenic protein-1 differentially regulates the mRNA expression of bone morphogenetic proteins and their receptors in primary cultures of osteoblasts
    • L.C. Yeh, R. Unda, and J.C. Lee Osteogenic protein-1 differentially regulates the mRNA expression of bone morphogenetic proteins and their receptors in primary cultures of osteoblasts J Cell Physiol 185 1 2000 87 97
    • (2000) J Cell Physiol , vol.185 , Issue.1 , pp. 87-97
    • Yeh, L.C.1    Unda, R.2    Lee, J.C.3
  • 18
    • 0027360838 scopus 로고
    • Human osteogenic protein-1 induces both chondroblastic and osteoblastic differentiation of osteoprogenitor cells derived from newborn rat calvaria
    • DOI 10.1083/jcb.123.4.921
    • I. Asahina, T.K. Sampath, I. Nishimura, and P.V. Hauschka Human osteogenic protein-1 induces both chondroblastic and osteoblastic differentiation of osteoprogenitor cells derived from newborn rat calvaria J Cell Biol 123 4 1993 921 933 (Pubitemid 23333580)
    • (1993) Journal of Cell Biology , vol.123 , Issue.4 , pp. 921-933
    • Asahina, I.1    Sampath, T.K.2    Nishimura, I.3    Hauschka, P.V.4
  • 19
    • 0034957648 scopus 로고    scopus 로고
    • Human BMP-7/OP-1 induces the growth and differentiation of adipocytes and osteoblasts in bone marrow stromal cell cultures
    • DOI 10.1002/jcb.1145
    • T.L. Chen, W.J. Shen, and F.B. Kraemer Human BMP-7/OP-1 induces the growth and differentiation of adipocytes and osteoblasts in bone marrow stromal cell cultures J Cell Biochem 82 2 2001 187 199 (Pubitemid 32606283)
    • (2001) Journal of Cellular Biochemistry , vol.82 , Issue.2 , pp. 187-199
    • Chen, T.L.1    Shen, W.-J.2    Kraemer, F.B.3
  • 20
    • 0142029486 scopus 로고    scopus 로고
    • Transcriptional regulation of the human Runx2/Cbfa1 gene promoter by bone morphogenetic protein-7
    • DOI 10.1016/S0303-7207(03)00151-5
    • L. Tou, N. Quibria, and J.M. Alexander Transcriptional regulation of the human Runx2/Cbfa1 gene promoter by bone morphogenetic protein-7 Mol Cell Endocrinol 205 1-2 2003 121 129 (Pubitemid 37297358)
    • (2003) Molecular and Cellular Endocrinology , vol.205 , Issue.1-2 , pp. 121-129
    • Tou, L.1    Quibria, N.2    Alexander, J.M.3
  • 21
    • 32144438313 scopus 로고    scopus 로고
    • Co-transfection with the osteogenic protein (OP)-1 gene and the insulin-like growth factor (IGF)-I gene enhanced osteoblastic cell differentiation
    • DOI 10.1016/j.bbamcr.2005.11.001, PII S0167488905002259
    • L.C. Yeh, and J.C. Lee Co-transfection with the osteogenic protein (OP)-1 gene and the insulin-like growth factor (IGF)-I gene enhanced osteoblastic cell differentiation Biochim Biophys Acta 1763 1 2006 57 63 (Pubitemid 43208732)
    • (2006) Biochimica et Biophysica Acta - Molecular Cell Research , vol.1763 , Issue.1 , pp. 57-63
    • Yeh, L.-C.C.1    Lee, J.C.2
  • 22
    • 33144468578 scopus 로고    scopus 로고
    • C-type natriuretic peptide enhances osteogenic protein-1-induced osteoblastic cell differentiation via smad5 phosphorylation
    • DOI 10.1002/jcb.20657
    • L.C. Yeh, M.C. Zavala, and J.C. Lee C-type natriuretic peptide enhances osteogenic protein-1-induced osteoblastic cell differentiation via Smad5 phosphorylation J Cell Biochem 97 3 2006 494 500 (Pubitemid 43265309)
    • (2006) Journal of Cellular Biochemistry , vol.97 , Issue.3 , pp. 494-500
    • Yeh, L.-C.C.1    Zavala, M.C.2    Lee, J.C.3
  • 23
    • 77953854477 scopus 로고    scopus 로고
    • OP-1 (BMP-7) stimulates osteoprogenitor cell differentiation in the presence of polymethylmethacrylate particles
    • S. Kann, R. Chiu, T. Ma, and S.B. Goodman OP-1 (BMP-7) stimulates osteoprogenitor cell differentiation in the presence of polymethylmethacrylate particles J Biomed Mater Res A 94 2 2010 485 488
    • (2010) J Biomed Mater Res A , vol.94 , Issue.2 , pp. 485-488
    • Kann, S.1    Chiu, R.2    Ma, T.3    Goodman, S.B.4
  • 25
    • 77649263952 scopus 로고    scopus 로고
    • RhBMP2/7 heterodimer: An osteoblastogenesis inducer of not higher potency but lower effective concentration compared with rhBMP2 and rhBMP7 homodimers
    • Y. Zheng, G. Wu, J. Zhao, L. Wang, P. Sun, and Z. Gu rhBMP2/7 heterodimer: an osteoblastogenesis inducer of not higher potency but lower effective concentration compared with rhBMP2 and rhBMP7 homodimers Tissue Eng Part A 16 3 2010 879 887
    • (2010) Tissue Eng Part A , vol.16 , Issue.3 , pp. 879-887
    • Zheng, Y.1    Wu, G.2    Zhao, J.3    Wang, L.4    Sun, P.5    Gu, Z.6
  • 26
    • 0032718092 scopus 로고    scopus 로고
    • In situ measurement of collagen synthesis by human bone cells with a Sirius Red-based colorimetric microassay: Effects of transforming growth factor β2 and ascorbic acid 2-phosphate
    • DOI 10.1007/s004180050447
    • H. Tullberg-Reinert, and G. Jundt In situ measurement of collagen synthesis by human bone cells with a sirius red-based colorimetric microassay: effects of transforming growth factor beta2 and ascorbic acid 2-phosphate Histochem Cell Biol 112 4 1999 271 276 (Pubitemid 29515494)
    • (1999) Histochemistry and Cell Biology , vol.112 , Issue.4 , pp. 271-276
    • Tullberg-Reinert, H.1    Jundt, G.2
  • 27
    • 0026068646 scopus 로고
    • Bone morphogenetic protein-2 stimulates alkaline phosphatase activity and collagen synthesis in cultured osteoblastic cells, MC3T3-E1
    • Y. Takuwa, C. Ohse, E.A. Wang, J.M. Wozney, and K. Yamashita Bone morphogenetic protein-2 stimulates alkaline phosphatase activity and collagen synthesis in cultured osteoblastic cells, MC3T3-E1 Biochem Biophys Res Commun 174 1 1991 96 101
    • (1991) Biochem Biophys Res Commun , vol.174 , Issue.1 , pp. 96-101
    • Takuwa, Y.1    Ohse, C.2    Wang, E.A.3    Wozney, J.M.4    Yamashita, K.5
  • 28
    • 0026325169 scopus 로고
    • Bone morphogenetic proteins (BMP-2 and BMP-3) promote growth and expression of the differentiated phenotype of rabbit chondrocytes and osteoblastic MC3T3-E1 cells in vitro
    • Y. Hiraki, H. Inoue, C. Shigeno, Y. Sanma, H. Bentz, and D.M. Rosen Bone morphogenetic proteins (BMP-2 and BMP-3) promote growth and expression of the differentiated phenotype of rabbit chondrocytes and osteoblastic MC3T3-E1 cells in vitro J Bone Miner Res 6 12 1991 1373 1385
    • (1991) J Bone Miner Res , vol.6 , Issue.12 , pp. 1373-1385
    • Hiraki, Y.1    Inoue, H.2    Shigeno, C.3    Sanma, Y.4    Bentz, H.5    Rosen, D.M.6
  • 29
    • 0026739256 scopus 로고
    • Recombinant human osteogenic protein-1 (hOP-1) induces new bone formation in vivo with a specific activity comparable with natural bovine osteogenic protein and stimulates osteoblast proliferation and differentiation in vitro
    • T.K. Sampath, J.C. Maliakal, P.V. Hauschka, W.K. Jones, H. Sasak, and R.F. Tucker Recombinant human osteogenic protein-1 (hOP-1) induces new bone formation in vivo with a specific activity comparable with natural bovine osteogenic protein and stimulates osteoblast proliferation and differentiation in vitro J Biol Chem 267 28 1992 20352 20362
    • (1992) J Biol Chem , vol.267 , Issue.28 , pp. 20352-20362
    • Sampath, T.K.1    Maliakal, J.C.2    Hauschka, P.V.3    Jones, W.K.4    Sasak, H.5    Tucker, R.F.6
  • 30
    • 0034574298 scopus 로고    scopus 로고
    • How cells read TGF-beta signals
    • J. Massague How cells read TGF-beta signals Nat Rev Mol Cell Biol 1 3 2000 169 178
    • (2000) Nat Rev Mol Cell Biol , vol.1 , Issue.3 , pp. 169-178
    • Massague, J.1
  • 31
    • 0042834336 scopus 로고    scopus 로고
    • BMP signaling components are expressed in human fracture callus
    • DOI 10.1016/S8756-3282(03)00191-1
    • P. Kloen, M. Di Paola, O. Borens, J. Richmond, G. Perino, and D.L. Helfet BMP signaling components are expressed in human fracture callus Bone 33 3 2003 362 371 (Pubitemid 37103253)
    • (2003) Bone , vol.33 , Issue.3 , pp. 362-371
    • Kloen, P.1    Di Paola, M.2    Borens, O.3    Richmond, J.4    Perino, G.5    Helfet, D.L.6    Goumans, M.J.7
  • 32
    • 2542441495 scopus 로고    scopus 로고
    • Bone morphogenetic protein-7 signals opposing transforming growth factor β in mesangial cells
    • DOI 10.1074/jbc.M311998200
    • S. Wang, and R. Hirschberg Bone morphogenetic protein-7 signals opposing transforming growth factor beta in mesangial cells J Biol Chem 279 22 2004 23200 23206 (Pubitemid 38685626)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.22 , pp. 23200-23206
    • Wang, S.1    Hirschberg, R.2
  • 33
    • 72049100698 scopus 로고    scopus 로고
    • The role of collagen crosslinking in differentiation of human mesenchymal stem cells and MC3T3-E1 cells
    • H. Fernandes, K. Dechering, E. Van Someren, I. Steeghs, M. Apotheker, and A. Leusink The role of collagen crosslinking in differentiation of human mesenchymal stem cells and MC3T3-E1 cells Tissue Eng Part A 15 12 2009 3857 3867
    • (2009) Tissue Eng Part A , vol.15 , Issue.12 , pp. 3857-3867
    • Fernandes, H.1    Dechering, K.2    Van Someren, E.3    Steeghs, I.4    Apotheker, M.5    Leusink, A.6
  • 34
    • 0034990212 scopus 로고    scopus 로고
    • Effect of bone morphogenetic protein-6 on haemopoietic stem cells and cytokine production in normal human bone marrow stroma
    • DOI 10.1006/cbir.2000.0662
    • N. Ahmed, J. Sammons, R.J. Carson, M.A. Khokher, and H.T. Hassan Effect of bone morphogenetic protein-6 on haemopoietic stem cells and cytokine production in normal human bone marrow stroma Cell Biol Int 25 5 2001 429 435 (Pubitemid 32530355)
    • (2001) Cell Biology International , vol.25 , Issue.5 , pp. 429-435
    • Ahmed, N.1    Sammons, J.2    Carson, R.J.3    Khokher, M.A.4    Hassan, H.T.5
  • 36
    • 0346996354 scopus 로고    scopus 로고
    • Hedgehog stimulates only osteoblastic differentiation of undifferentiated KS483 cells
    • DOI 10.1016/j.bone.2003.07.004
    • G. van der Horst, H. Farih-Sips, C.W. Lowik, and M. Karperien Hedgehog stimulates only osteoblastic differentiation of undifferentiated KS483 cells Bone 33 6 2003 899 910 (Pubitemid 37543566)
    • (2003) Bone , vol.33 , Issue.6 , pp. 899-910
    • Van Der Horst, G.1    Farih-Sips, H.2    Lowik, C.W.G.M.3    Karperien, M.4
  • 39
    • 67349155526 scopus 로고    scopus 로고
    • New insights into BMP-7 mediated osteoblastic differentiation of primary human mesenchymal stem cells
    • K. Lavery, S. Hawley, P. Swain, R. Rooney, D. Falb, and M.H. Alaoui-Ismaili New insights into BMP-7 mediated osteoblastic differentiation of primary human mesenchymal stem cells Bone 45 1 2009 27 41
    • (2009) Bone , vol.45 , Issue.1 , pp. 27-41
    • Lavery, K.1    Hawley, S.2    Swain, P.3    Rooney, R.4    Falb, D.5    Alaoui-Ismaili, M.H.6
  • 40
    • 0032535785 scopus 로고    scopus 로고
    • Bone morphogenetic proteins induce the expression of noggin, which limits their activity in cultured rat osteoblasts
    • E. Gazzerro, V. Gangji, and E. Canalis Bone morphogenetic proteins induce the expression of noggin, which limits their activity in cultured rat osteoblasts J Clin Invest 102 12 1998 2106 2114 (Pubitemid 29018817)
    • (1998) Journal of Clinical Investigation , vol.102 , Issue.12 , pp. 2106-2114
    • Gazzerro, E.1    Gangji, V.2    Canalis, E.3


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