Tumor-dependent down-regulation of the ζ-chain in T-cells is detectable in early breast cancer and correlates with immune cell function

International Journal of Cancer

Volumn 131, Issue 1, 2012, Pages 129-139

  Boniface, J De ^a,b   Poschke, I ^a   Mao, Y ^a   Kiessling, R ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

breast cancer; immunosuppression; NK cells; T cells; zeta chain

Indexed keywords

CYTOKINE; NATURAL KILLER CELL RECEPTOR; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR ZETA CHAIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BLOOD SAMPLING; BREAST CANCER; BREAST TUMOR; CANCER STAGING; CANCER SURGERY; CD8+ T LYMPHOCYTE; CELL ACTIVITY; CELL FUNCTION; CELL PROLIFERATION; CELL STIMULATION; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; EARLY CANCER; EX VIVO STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCOMPETENT CELL; LYMPH NODE; LYMPHOCYTE SUBPOPULATION; NATURAL KILLER CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ADULT; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; CD8-POSITIVE T-LYMPHOCYTES; CYTOKINES; FEMALE; HUMANS; KI-67 ANTIGEN; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; MIDDLE AGED; NEOPLASM STAGING; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 84860220430     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.26355     Document Type: Article

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