Tridimensional personalities and polymorphism of dopamine D2 receptor among heroin addicts

Biological Research for Nursing

Volumn 14, Issue 2, 2012, Pages 188-196

  Teh, Lay K ^a   Izuddin, Abu F ^a   Fazleen, H M H ^a   Zakaria, Zainul A ^a,b   Salleh, Mohd Zaki ^a  

^a UNIVERSITI TEKNOLOGI MARA   (Malaysia)

^b UNIVERSITY PUTRA MALAYSIA   (Malaysia)

Author keywords

dopamine D.r.ceptor (DRD2); heroin addicts; Taq1A; Tridimensional Personality Questionnaire (TPQ)

Indexed keywords

DIAMORPHINE; DOPAMINE 2 RECEPTOR; PRIMER DNA;

ARTICLE; GENETIC POLYMORPHISM; GENETICS; HUMAN; MALE; NUCLEOTIDE SEQUENCE; OPIATE ADDICTION; PERSONALITY; PSYCHOLOGICAL ASPECT; QUESTIONNAIRE;

BASE SEQUENCE; DNA PRIMERS; HEROIN; HUMANS; MALE; OPIOID-RELATED DISORDERS; PERSONALITY; POLYMORPHISM, GENETIC; QUESTIONNAIRES; RECEPTORS, DOPAMINE D2;

EID: 84860207826     PISSN: 10998004     EISSN: 15524175     Source Type: Journal    
DOI: 10.1177/1099800411405030     Document Type: Article

References (37)

1. Ball S. A.Personality traits, problems, and disorders: Clinical applications to substance use disorders.Journal of Research in Personality. 2005;39:84-102.
2. Bardo M. T.,Donohew R. L.,Harrington N. G.Psychobiology of novelty seeking and drug seeking behavior.Behavioural Brain Research. 1996;77:23-43.
3. Bechara A.,Dolan S.,Denburg N.,Hindes A.,Anderson S. W.,Nathan P. E.Decision-making deficits, linked to a dysfunctional ventromedial prefrontal cortex, revealed in alcohol and stimulant abusers.Neuropsychologia. 2001;39:376-389.
4. Berggren U.,Fahlke C.,Aronsson E.,Karanti A.,Eriksson M.,Blennow K.,Balldin J.The TAQI DRD2 A1 allele is associated with alcohol-dependence although its effect size is small.Alcohol. 2006;41:479-485.
5. Blum K.,Braverman E. R.,Wood R. C.,Gill J.,Li C.,Chen T. J. H.,Cull J. G.Increased prevalence of the Taq I A1 allele of the dopamine receptor gene (DRD2) in obesity with comorbid substance use disorder: a preliminary report.Pharmacogenetics. 1996;6:287-305.
6. Blum K.,Noble E. P.,Sheridan P. J.,Montgomery A.,Ritchie T.,Jagadeeswaran P.,Cohn J. B.Allelic association of human dopamine D2 receptor gene in alcoholism.Journal of the American Medical Association. 1990;263:2055-2060.
7. Chih-Hung K.,Ju-Yu Y.,Cheng-Chung C.,Sue-Huei C.,Kuanyi W.,Cheng-Fang Y.Tridimensional personality of adolescents with internet addiction and substance use experience.Canadian Journal of Psychiatry. 2006;51:887-894.
8. Cloninger C. R.Neurogenetic adaptive mechanisms in alcoholism.Science. 1987a;236:410-416.
9. Cloninger C. R.A systematic method for clinical description and classification of personality variants: A proposal.Archives of General Psychiatry. 1987b;44:573-588.
10. Cloninger C. R.,Sigvardsson S.,Przybeck T. R.,Svrakic D. M.Personality antecedents of alcoholism in a national area probability sample.European Archives of Psychiatry and Clinical Neuroscience. 1995;245:239-244.
11. Comings D. E.,Muhleman D.,Ahn C.,Gysin R.,Flanagan S. D.The dopamine D2 receptor gene: A genetic risk factor in substance abuse.Drug and Alcohol Dependence. 1994;34:175-180.
12. Dalley J. W.,Fryer T. D.,Brichard L.,Robinson E. S. J.,Theobald D. E. H.,Laane K.Nucleus accumbens D2/3 receptors predict trait impulsivity and cocaine reinforcement.Science. 2007;315:1267-1270.
13. Dawson-Sanders B.,Trapp R. G.Basic and clinical biostatistics. 1994). Basic and clinical biostatistics3rd ed.). Norwalk, CT: Appleton & Lange.Norwalk, CT: Appleton & Lange; 1994:.
14. Foll B. L.,Gallo A.,Strat Y. L.,Lu L.,Gorwood P.Genetics of dopamine receptors and drug addiction: A comprehensive review.Behavioural Pharmacology. 2009;20:1-17.
15. Gelernter J.,Kranzler H.D2 dopamine receptor gene (DRD2) allele and haplotype frequencies in alcohol dependent and control subjects: No association with phenotype or severity of phenotype.Neuropsychopharmacology. 1999;20:640-649.
16. Gerra G. S.,Bertacca S.,Zaimovic A.,Pirani M.,Branchi B.,Ferri M.Relationship of personality traits and drug of choice by cocaine addicts and heroin addicts.Substance Use & Misuse. 2008;43:317-330.
17. Goldman D.,Urbanek M.,Guenther D.,Robin R.,Long J. C.A functionally deficient DRD2 variant [Ser311Cys] is not linked to alcoholism and substance abuse.Alcohol. 1998;16:47-52.
18. Gorwood P.,Wohl M.,Le Strat Y.,Rouillon F.Gene-environment interactions in addictive disorders: Epidemiological and methodological aspects.Comptes Rendus Biologies. 2007;330:329-338.
19. Goudriaan A. E.,Oosterlaan J.,de Beurs E.,Van den Brink W.Pathological gambling: A comprehensive review of biobehavioral findings.Neuroscience and Biobehavioral Reviews. 2004;28:123-141.
20. Hou Q. F.,Li S. B.Potential association of DRD2 and DAT1 genetic variation with heroin dependence.Neuroscience Letters. 2009;464:127-130.
21. Kreek M. J.,Bart G.,Lilly C.,Laforge K. S,Nielsen D. A.Pharmacogenetics and human molecular genetics of opiate and cocaine addiction and their treatments.Pharmacological Reviews. 2005;57:1-26.
22. Lawford B. R.,Young R. M.,Noble E. P.,Sargent J.,Rowell J.,Shadforth S.,Ritchie T.The D(2) dopamine receptor A(1) allele and opioid dependence: Association with heroin use and response to methadone treatment.American Journal of Medical Genetics. 2000;96:592-598.
23. Moyer P.A.Substance abuse. A multidimensional assessment and treatment approach. 1992). Substance abuse. A multidimensional assessment and treatment approach1st ed.). New York: SLACK Inc.New York: SLACK Inc; 1992:.
24. Noble E. P.Phenotypic expression of the D2 dopamine receptor: A reinforcement of reward gene?.Biological Psychiatry. 1997;295:42.
25. Noble E. P.Addiction and its reward process through polymorphisms of the D2 dopamine receptor gene: A review.European Psychiatry. 2000;15:79-89.
26. O'Hara B. F.,Smith S. S.,Bird G.,Persico A. M.,Suarez B. K.,Cutting G. R.Dopamine D2 receptor RFLPs, haplotypes and their association with substance use in Black and Caucasian research volunteers.Human Heredity. 1993;43:209-218.
27. Smith D. E.,Seymour R. B.Clinician's guide to substance abuse. New York: McGraw-Hill; 2001:.
28. Smith L.,Watson M.,Gates S.,Ball D.,Foxcroft D.Meta-analysis of the association of the Taq1A polymorphism with the risk of alcohol dependency: A HuGE gene-disease association review.American Journal of Epidemiology. 2007;167:125-138.
29. Smith S. S.,O'Hara B. F.,Persico A. M.,Gorelick D. A.,Newlin D. B.,Vlahov D.Genetic vulnerability in drug abuse: The dopamine D2 receptor TaqI B RFLP is more frequent in polysubstance abusers.Archives of General Psychiatry. 1992;49:723-727.
30. Spitz M. R.,Shi H.,Yang F.,Hudmon K. S.,Jiang H.,Chamberlain R. M.,Wu X.Case-control study of the D2 dopamine receptor gene and smoking status in lung cancer patients.Journal of the National Cancer Institute. 1998;90:359-363.
31. Tikkanen R.,Holi M.,Lindberg N.,Virkkunen M.Tridimensional Personality Questionnaire data on alcoholic violent offenders: Specific connections to severe impulsive cluster B personality disorders and violent criminality.BioMed Central Psychiatry. 2007;7:1-7.
32. Tyndale R. F.,Droll K. P.,Sellers E. M.Genetically deficient CYP2D6 metabolism provides protection against oral dependence.Pharmacogenetics. 1997;7:375-379.
33. Van den Bosch L.,Verheul R.Patients with addiction and personality disorder: Treatment outcomes and clinical implications.Current Opinions in Psychiatry. 2007;20:67-71.
34. Verdejo-Garcia A.,Perez-Garcia M.Profile of executive deficits in cocaine and heroin polysubstance users: Common and differential effects on separate executive components.Psychopharmacology. 2007;517-530:190.
35. Volkow N. D.,Wang G. J.,Fowler J. S.,Thanos P. P.,Logan J.,Gatley S. J.Brain DA D2 receptors predict reinforcing effects of stimulants in humans: Replication study.Synapse. 2002;46:79-82.
36. Vukov M.,Baba-Milkic N.,Lecic D.Personality dimensions of opiate addicts.Acta Psychiatrica Scandinavica. 1995;91:103-107.
37. Zhang Y.,Bertolino A.,Fazio L.,Blasi G.,Rampino A.,Romano R.,Sadée W.Polymorphisms in human dopamine D2 receptor gene affect gene expression, splicing, and neuronal activity during working memory.Proceedings of the National Academy of Sciences of the United States of America. 2007;104:20552-20557.