Nitric oxide stress in sporadic inclusion body myositis muscle fibres: Inhibition of inducible nitric oxide synthase prevents interleukin-1β- induced accumulation of β-amyloid and cell death

Brain

Volumn 135, Issue 4, 2012, Pages 1102-1114

  Schmidt, Jens ^a   Barthel, Konstanze ^a   Zschüntzsch, Jana ^a   Muth, Ingrid E ^a   Swindle, Emily J ^b   Hombach, Anja ^a   Sehmisch, Stephan ^a   Wrede, Arne ^a   Lühder, Fred ^a   Gold, Ralf ^a   Dalakas, Marinos C ^c  

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^c UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

IL 1 ; myositis; neuroinflammation; nitric oxide; amyloid

Indexed keywords

3 NITROTYROSINE; AMYLOID BETA PROTEIN; DICHLOROFLUORESCEIN; GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; MESSENGER RNA; N [3 (AMINOMETHYL)BENZYL]ACETAMIDINE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; THIOFLAVINE;

ARTICLE; CELL DEATH; CONTROLLED STUDY; DERMATOMYOSITIS; FLOW CYTOMETRY; FLUORESCENCE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INCLUSION BODY MYOSITIS; MAJOR CLINICAL STUDY; MUSCLE; MUSCULAR DYSTROPHY; MYOBLAST; MYOTUBE; OXIDATIVE STRESS; POLYMYOSITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER; UPREGULATION;

EID: 84860197247     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/aws046     Document Type: Article

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