The relationship between time to surgical debridement and incidence of infection in grade III open fractures

Strategies in Trauma and Limb Reconstruction

Volumn 7, Issue 1, 2012, Pages 33-37

  Singh, Jagwant ^a   Rambani, Rohit ^a   Hashim, Zaid ^a   Raman, Raghu ^a   Sharma, Hemant Kumar ^a  

^a HULL ROYAL INFIRMARY   (United Kingdom)

Author keywords

Debridement; Grade III open fractures; Infection rate

Indexed keywords

EID: 84860193677     PISSN: 18288936     EISSN: 18288928     Source Type: Journal    
DOI: 10.1007/s11751-012-0130-y     Document Type: Article

References (31)

1. Okike K, Bhattacharyya T (2006) Trends in the management of open fractures. A critical analysis. J Bone Joint Surg Am 88: 2739-2748.
2. Zalavras CG, Marcus RE, Levin LS et al (2008) Management of open fractures and subsequent complications. Instr Course Lect 57: 51-63.
3. Giannoudis PV, Papakostidis C, Roberts C (2006) A review of the management of open fractures of the tibia and femur. J Bone Joint Surg Br 88: 281-289.
4. Cole JD, Ansel LJ, Schwartzberg R (1995) A sequential protocol for management of severe open tibial fractures. Clin Orthop Relat Res 315: 84-103.
5. Webb LX, Bosse MJ, Castillo RC et al (2007) Analysis of surgeon-controlled variables in the treatment of limb-threatening type-III open tibial diaphyseal fractures. J Bone Joint Surg Am 89: 923-928.
6. Al-Arabi YB, Nader M, Hamidian-Jahromi AR et al (2007) The effect of the timing of antibiotics and surgical treatment on infection rates in open long-bone fractures: a 9-year prospective study from a district general hospital. Injury 38: 900-905.
7. Zalavras CG, Marcus RE, Levin LS et al (2007) Management of open fractures and subsequent complications. J Bone Joint Surg Am 89: 884-895.
8. Gregory P, Sanders R (1995) The management of severe fractures of the lower extremities. Clin Orthop Relat Res 318: 95-105.
9. Patzakis MJ, Wilkins J, Moore TM (1983) Considerations in reducing the infection rate in open tibial fractures. Clin Orthop Relat Res 178: 36-41.
10. Gustilo RB, Anderson JT (1976) Prevention of infection in the treatment of one thousand and twenty-five open fractures of long bones: retrospective and prospective analyses. J Bone Joint Surg Am 58: 453-458.
11. Cierny G III, Byrd HS, Jones RE (1983) Primary versus delayed soft tissue coverage for severe open tibial fractures. A comparison of results. Clin Orthop Relat Res178: 54-63.
12. Spencer J, Smith A, Woods D (2004) The effect of time delay on infection in open long-bone fractures: a 5-year prospective audit from a district general hospital. Ann R Coll Surg Engl 86: 108-112.
13. Charalambous CP, Siddique I, Zenios M et al (2005) Early versus delayed surgical treatment of open tibial fractures: effect on the rates of infection and need of secondary surgical procedures to promote bone union. Injury 36: 656-661.
14. Kindsfater K, Jonassen EA (1995) Osteomyelitis in grade II and III open tibia fractures with late debridement. J Orthop Trauma 9: 121-127.
15. Friedrich P (1898) Die Aseptische Versorgung frischer Wundern. Arch Klin Chir 57: 288-310.
16. Robson MC, Duke WF, Krizek TJ (1973) Rapid bacterial screening in the treatment of civilian wounds. J Surg Res 14: 426-430.
17. Gustilo RB, Mendoza RM, Williams DN (1984) Problems in the management of type III (severe) open fractures: a new classification of type III open fractures. J Trauma 24: 742-746.
18. BOA (2009) Standards for the management of open fractures of the lower limb. BAPRAS 1-24. http://www. boa. ac. uk/site/showpublications. aspx?id=59.
19. Robson MC (1997) Wound infection. A failure of wound healing caused by an imbalance of bacteria. Surg Clin North Am 77: 637-650.
20. Kreder HJ, Armstrong P (1995) A review of open tibia fractures in children. J Pediatr Orthop 15: 482-488.
21. Pollak AN, Jones AL, Castillo RC et al (2010) The relationship between time to surgical debridement and incidence of infection after open high-energy lower extremity trauma. J Bone Joint Surg Am 92: 7-15.
22. Sungaran J, Harris I, Mourad M (2007) The effect of time to theatre on infection rate for open tibia fractures. ANZ J Surg 77: 886-888.
23. Skaggs DL, Friend L, Alman B et al (2005) The effect of surgical delay on acute infection following 554 open fractures in children. J Bone Joint Surg Am 87: 8-12.
24. Harley BJ, Beaupre LA, Jones CA et al (2002) The effect of time to definitive treatment on the rate of nonunion and infection in open fractures. J Orthop Trauma 16: 484-490.
25. Bednar DA, Parikh J (1993) Effect of time delay from injury to primary management on the incidence of deep infection after open fractures of the lower extremities caused by blunt trauma in adults. J Orthop Trauma 7: 532-535.
26. Gosselin RA, Roberts I, Gillespie WJ (2004) Antibiotics for preventing infection in open limb fractures. Cochrane Database Syst Rev 1: CD003764.
27. Patzakis MJ, Wilkins J (1989) Factors influencing infection rate in open fracture wounds. Clin Orthop Relat Res 243: 36-40.
28. Gustilo RB, Gruninger RP, Davis T (1987) Classification of type III (severe) open fractures relative to treatment and results. Orthopedics 10: 1781-1788.
29. Naique SB, Pearse M, Nanchahal J (2006) Management of severe open tibial fractures: the need for combined orthopaedic and plastic surgical treatment in specialist centres. J Bone Joint Surg Br 88: 351-357.
30. Worlock P, Slack R, Harvey L et al (1994) The prevention of infection in open fractures: an experimental study of the effect of fracture stability. Injury 25: 31-38.
31. Pallister I, Empson K (2005) The effects of surgical fracture fixation on the systemic inflammatory response to major trauma. J Am Acad Orthop Surg 13: 93-100.