Members of the NODE (Nanog and Oct4-associated deacetylase) complex and SOX-2 promote the initiation of a natural cellular reprogramming event in vivo

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 17, 2012, Pages 6596-6601

  Kagias, Konstantinos ^a   Ahier, Arnaud ^a   Fischer, Nadine ^a   Jarriault, Sophie ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

Metaplasia; Regenerative medicine; SANT; Transdifferentiation

Indexed keywords

HISTONE DEACETYLASE; HOX PROTEIN; NOTCH RECEPTOR; OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2;

ARTICLE; CAENORHABDITIS ELEGANS; CELL DIVISION; CELL MIGRATION; CHROMATIN; CYTOPLASM; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; ENZYME ACTIVITY; GENETIC ANALYSIS; IN VIVO STUDY; MOTONEURON; NONHUMAN; NUCLEAR REPROGRAMMING; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; RNA INTERFERENCE; WORM;

ANIMALS; CAENORHABDITIS ELEGANS; CELL DIFFERENTIATION; HELA CELLS; HOMEODOMAIN PROTEINS; HUMANS; OCTAMER TRANSCRIPTION FACTOR-3; SOXB1 TRANSCRIPTION FACTORS;

EID: 84860176217     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1117031109     Document Type: Article

References (36)

1. Takahashi K, Yamanaka S (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126:663-676. (Pubitemid 44233629)
2. Hajduskova M, Ahier A, Daniele T, Jarriault S (2012) Cell plasticity in Caenorhabditis elegans: From induced to natural cell reprogramming. Genesis 50:1-17.
3. Chambers I, Tomlinson SR (2009) The transcriptional foundation of pluripotency. Development 136:2311-2322.
4. Liang J, et al. (2008) Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells. Nat Cell Biol 10:731-739. (Pubitemid 351772939)
5. Yuri S, et al. (2009) Sall4 is essential for stabilization, but not for pluripotency, of embryonic stem cells by repressing aberrant trophectoderm gene expression. Stem Cells 27:796-805.
6. Tsubooka N, et al. (2009) Roles of Sall4 in the generation of pluripotent stem cells from blastocysts and fibroblasts. Genes Cells 14:683-694.
7. Wong CC, Gaspar-Maia A, Ramalho-Santos M, Reijo Pera RA (2008) High-efficiency stem cell fusion-mediated assay reveals Sall4 as an enhancer of reprogramming. PLoS ONE, 10.1371/journal.pone.0001955.
8. Sakaki-Yumoto M, et al. (2006) The murine homolog of SALL4, a causative gene in Okihiro syndrome, is essential for embryonic stem cell proliferation, and cooperates with Sall1 in anorectal, heart, brain and kidney development. Development 133:3005-3013. (Pubitemid 44314277)
9. Zhang J, et al. (2006) Sall4 modulates embryonic stem cell pluripotency and early embryonic development by the transcriptional regulation of Pou5f1. Nat Cell Biol 8:1114-1123. (Pubitemid 44473607)
10. Manavathi B, Kumar R (2007) Metastasis tumor antigens, an emerging family of multifaceted master coregulators. J Biol Chem 282:1529-1533. (Pubitemid 47076673)
11. Xue Y, et al. (1998) NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities. Mol Cell 2:851-861. (Pubitemid 128378992)
12. Lauberth SM, Rauchman M (2006) A conserved 12-amino acid motif in Sall1 recruits the nucleosome remodeling and deacetylase corepressor complex. J Biol Chem 281:23922-23931. (Pubitemid 44274167)
13. Kiefer SM, McDill BW, Yang J, Rauchman M (2002) Murine Sall1 represses transcription by recruiting a histone deacetylase complex. J Biol Chem 277:14869-14876. (Pubitemid 34952560)
14. Jarriault S, Schwab Y, Greenwald I (2008) A Caenorhabditis elegans model for epithelial-neuronal transdifferentiation. Proc Natl Acad Sci USA 105:3790-3795. (Pubitemid 351723477)
15. Bantignies F, Cavalli G (2006) Cellular memory and dynamic regulation of polycomb group proteins. Curr Opin Cell Biol 18:275-283.
16. Kaji K, Nichols J, Hendrich B (2007) Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells. Development 134:1123-1132. (Pubitemid 46630080)
17. Richard JP, et al. (2011) Direct in vivo cellular reprogramming involves transition through discrete, non-pluripotent steps. Development 138:1483-1492.
18. Kamath RS, et al. (2003) Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 421:231-237. (Pubitemid 36139121)
19. Solari F, Bateman A, Ahringer J (1999) The Caenorhabditis elegans genes egl-27 and egr-1 are similar to MTA1, a member of a chromatin regulatory complex, and are redundantly required for embryonic patterning. Development 126:2483-2494. (Pubitemid 29299017)
20. Herman MA, et al. (1999) EGL-27 is similar to a metastasis-associated factor and controls cell polarity and cell migration in C. elegans. Development 126:1055-1064. (Pubitemid 29142012)
21. de la Cruz X, Lois S, Sánchez-Molina S, Martínez- Balbás MA (2005) Do protein motifs read the histone code? Bioessays 27:164-175. (Pubitemid 40292388)
22. Yu J, Li Y, Ishizuka T, Guenther MG, Lazar MA (2003) A SANT motif in the SMRT corepressor interprets the histone code and promotes histone deacetylation. EMBO J 22:3403-3410. (Pubitemid 36834870)
23. Wang L, Charroux B, Kerridge S, Tsai CC (2008) Atrophin recruits HDAC1/2 and G9a to modify histone H3K9 and to determine cell fates. EMBO Rep 9:555-562. (Pubitemid 351772919)
24. Bürglin TR, Ruvkun G (2001) Regulation of ectodermal and excretory function by the C. elegans POU homeobox gene ceh-6. Development 128:779-790. (Pubitemid 32229254)
25. Reményi A, et al. (2003) Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancers. Genes Dev 17:2048-2059. (Pubitemid 36999330)
26. Mallanna SK, et al. (2010) Proteomic analysis of Sox2-associated proteins during early stages of mouse embryonic stem cell differentiation identifies Sox21 as a novel regulator of stem cell fate. Stem Cells 28:1715-1727.
27. Pardo M, et al. (2010) An expanded Oct4 interaction network: Implications for stem cell biology, development, and disease. Cell Stem Cell 6:382-395.
28. van den Berg DL, et al. (2010) An Oct4-centered protein interaction network in embryonic stem cells. Cell Stem Cell 6:369-381.
29. Ch'ng Q, Kenyon C (1999) egl-27 generates anteroposterior patterns of cell fusion in C. elegans by regulating Hox gene expression and Hox protein function. Development 126:3303-3312. (Pubitemid 29396771)
30. Elling U, Klasen C, Eisenberger T, Anlag K, Treier M (2006) Murine inner cell mass-derived lineages depend on Sall4 function. Proc Natl Acad Sci USA 103:16319-16324. (Pubitemid 44715194)
31. Nichols J, et al. (1998) Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 95:379-391. (Pubitemid 28507326)
32. Avilion AA, et al. (2003) Multipotent cell lineages in early mouse development depend on SOX2 function. Genes Dev 17:126-140. (Pubitemid 36062514)
33. Pevny L, Placzek M (2005) SOX genes and neural progenitor identity. Curr Opin Neurobiol 15:7-13. (Pubitemid 40249955)
34. Christen B, Robles V, Raya M, Paramonov I, Izpisúa Belmonte JC (2010) Regeneration and reprogramming compared. BMC Biol, 10.1186/1741-7007-8-5.
35. Neff AW, et al. (2005) Expression of Xenopus XlSALL4 during limb development and regeneration. Dev Dyn 233:356-367. (Pubitemid 40734037)
36. Zuryn S, Le Gras S, Jamet K, Jarriault S (2010) A strategy for direct mapping and identification of mutations by whole-genome sequencing. Genetics 186:427-430.