Rethinking the war on cancer: Multidisciplinary collaborations between biologists and physical scientists

Future Oncology

Volumn 8, Issue 4, 2012, Pages 339-341

  Rosenthal, Devin T ^a   Merajver, Sofia D ^b  

^a TUFTS UNIVERSITY   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

breast cancer; collaboration; metastasis; multidisciplinary; p38 MAPK

Indexed keywords

SIGNAL TRANSDUCING ADAPTOR PROTEIN; SYNAPTOPHYSIN; TRASTUZUMAB;

BIOLOGY; BREAST CANCER; CANCER CELL; CANCER RESEARCH; CANCER SURVIVAL; CANCER THERAPY; CELL FUNCTION; CELL INVASION; CELL MOTILITY; CELL PROLIFERATION; CYTOARCHITECTURE; GENE DOSAGE; GENE MUTATION; GENE REGULATORY NETWORK; HUMAN; MICROENVIRONMENT; NATURAL SCIENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; SCIENTIST; SINGLE NUCLEOTIDE POLYMORPHISM; TUMOR SUPPRESSOR GENE;

BIOLOGY; COOPERATIVE BEHAVIOR; HUMANS; NEOPLASMS; PHYSICS; RESEARCH PERSONNEL;

EID: 84860159418     PISSN: 14796694     EISSN: 17448301     Source Type: Journal    
DOI: 10.2217/fon.12.13     Document Type: Review

References (7)

1. Riaz M, Berns EM, Sieuwerts AM et al. Correlation of breast cancer susceptibility loci with patient characteristics, metastasis-free survival, and mRNA expression of the nearest genes. Breast Cancer Res. Treat. doi:10.1007/s10549-011-1663-3 (2011) (Epub ahead of print).
2. Druker BJ, Tamura S, Buchdunger E et al. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat. Med. 2(5), 561-566 (1996).
3. Vogel CL, Cobleigh MA, Tripathy D et al. Effcacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. J. Clin. Oncol. 20(3), 719-726 (2002). (Pubitemid 34111379)
4. Rosenthal DT, Iyer H, Escudero S et al. p38y promotes breast cancer cell motility and metastasis through regulation of RhoC GTPase, cytoskeletal architecture, and a novel leading edge behavior. Cancer Res. 71(20), 6338-6349 (2011).
5. Fu J, Wang YK, Yang MT et al. Mechanical regulation of cell function with geometrically modulated elastomeric substrates. Nat. Methods 7(9), 733-736 (2010).
6. Gupta PB, Fillmore CM, Jiang G et al. Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells. Cell 146(4), 633-644 (2011).
7. Anderson AR, Weaver AM, Cummings PT, Quaranta V. Tumor morphology and phenotypic evolution driven by selective pressure from the microenvironment. Cell 127(5), 905-915 (2006). (Pubitemid 44792251)