Current status of vaccines against infectious bursal disease

Avian Pathology

Volumn 41, Issue 2, 2012, Pages 133-139

  Müller, Hermann ^a   Mundt, Egbert ^b   Eterradossi, Nicolas ^c   Islam, M Rafiqul ^d  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b IDT Biologika GmbH   (Germany)

^c FRENCH AGENCY FOR FOOD   (France)

^d BANGLADESH AGRICULTURAL UNIVERSITY   (Bangladesh)

Author keywords

[No Author keywords available]

Indexed keywords

LIVE VACCINE; VIRUS ANTIBODY; VIRUS VACCINE;

ANIMAL; ANIMAL DISEASE; ARTICLE; BIRD DISEASE; BIRNAVIRUS INFECTION; CHICKEN; GENETIC ENGINEERING; IMMUNOLOGY; INFECTIOUS BURSAL DISEASE VIRUS; METHODOLOGY; VIROLOGY;

ANIMALS; ANTIBODIES, VIRAL; BIRNAVIRIDAE INFECTIONS; CHICKENS; GENETIC ENGINEERING; INFECTIOUS BURSAL DISEASE VIRUS; POULTRY DISEASES; VACCINES, ATTENUATED; VIRAL VACCINES;

EID: 84860125708     PISSN: 03079457     EISSN: 14653338     Source Type: Journal    
DOI: 10.1080/03079457.2012.661403     Document Type: Article

References (96)

1. Allan, W.H., Faragher, J.T. and Cullen, G.A. 1972. Immunosuppression by the infectious bursal agent in chickens immunized against Newcastle disease. Veterinary Record, 90: 511-512.
2. Azad, A.A., Jagadish, M.N., Brown, M. and Hudson, P. 1987. Deletion mapping and expression in E. coli of the large segment of a birnavirus. Virology, 161: 145-152.
3. Bayliss, C.D., Peters, R.W., Cook, J.K., Reece, R.L., Howes, K., Binns, M.M. and Boursnell, M.E. 1991. A recombinant fowlpox virus that expresses the VP2 antigen of infectious bursal disease virus induces protection against mortality by the virus. Archives of Virology, 120: 193-205.
4. Becht, H., Müller, H. and Müller, H.K. 1988. Comparative studies and antigenic properties of two serotypes of infectious bursal disease virus. Journal of General Virology, 69: 631-640.
5. Block, H., Meyer-Block, K., Rebeski, D.E., Scharr, H., de Wit, S., Rohn, K. and Rautenschlein, S. 2007. A field study on the significance of vaccination against infectious bursal disease virus (IBDV) at the optimal time point in broiler flocks with maternally derived IBDV antibodies. Avian Pathology, 36: 401-409.
6. Box, P. 1989, High maternal antibodies help chicks beat virulent strains. World Poultry, March, 17-19.
7. Bublot, M., Pritchard, N., Le Gros, F.X. and Goutebroze, S. 2007. Use of vectored vaccine against infectious bursal disease of chickens in the face of high-titred maternally derived antibody. Journal of Comparative Pathology, 137: S81-S84.
8. Cao, Y.C., Shi, Q.C., Ma, J.Y., Xie, Q.M. and Bi, Y.Z. 2005. Vaccination against very virulent infectious bursal disease virus using recombinant T4 bacteriophage displaying viral protein VP2. Acta Biochimica Biophysica Sinica (Shanghai), 37: 657-664.
9. Chettle, N., Stuart, J.C. and Wyeth, P.J. 1989. Outbreak of virulent infectious bursal disease in East Anglia. Veterinary Record, 125: 271-272.
10. Cosgrove, A.S. 1962. An apparently new disease of chickens-avian nephrosis. Avian Diseases, 6: 385-389.
11. Darteil, R., Bublot, M., Laplace, E., Bouquet, J.-F., Audonnet, J.-C. and Rivière, M. 1995. Herpesvirus of turkey recombinant viruses expressing infectious bursal disease virus (IBDV) VP2 immunogen induce protection against an IBDV virulent challenge in chickens. Virology, 211: 481-490.
12. Davison, F., Magor, K.E. and Kaspers, B. 2008. "Structure and evolution of avian immunoglobulins". In Avian Immunology, 1st edn, Edited by: Davison, F., Kaspers, B. and Schat, K.A. 107-128. London: Academic Press.
13. Delmas, B. 2008. "Birnaviruses". In Encyclopedia of Virology, 3rd edn, Edited by: Mahy, B.W.J. and van Regenmortel, M.H.V. Vol. 1, 321-328. Oxford: Elsevier.
14. De Wit, J.J. 1998. Gumboro disease: estimation of optimal time of vaccination by the Deventer formula. Polish Veterinary Journal, 3: 19-22.
15. Dobos, P., Hill, B.J., Hallet, R., Kells, D.T., Becht, H. and Tenninges, D. 1979. Biophysical and biochemical characterization of five animal viruses with bisegmented double-stranded RNA genomes. Journal of Virology, 32: 593-605.
16. Eterradossi, N. and Saif, Y.M. 2008. "Infectious bursal disease". In Diseases of Poultry, 12th edn, Edited by: Saif, Y.M., Fadly, A.M., Glisson, J.R., McDougald, L.R., Nolan, L.K. and Swayne, D.E. 185-208. Ames, IA: Blackwell Publishing.
17. Eterradossi, N., Gauthier, C., Reda, I., Comte, S., Rivallan, G., Toquin, D., De Boisseson, C., Lamande, J., Jestin, V., Morin, Y., Cazaban, C. and Borne, P.M. 2004. Extensive antigenic changes in an atypical isolate of infectious bursal disease virus and experimental clinical control of this virus with an antigenically classical live vaccine. Avian Pathology, 33: 423-431.
18. Fahey, K.J., Crooks, J.K. and Fraser, R.A. 1987. Assessment by ELISA of passively aquired protection against infectious bursal disease virus in chickens. Australian Veterinary Journal, 64: 203-207.
19. Fahey, K.J., Erny, K. and Crooks, J. 1989. A conformational immunogen on VP2 of infectious bursal disease virus that induces virus-neutralizing antibodies that passively protect chickens. Journal of General Virology, 70: 1473-1481.
20. Fahey, K.J., Chapman, A.J., Macreadie, I.G., Vaughan, P.R., McKern, N.M., Skicko, J.I., Ward, C.W. and Azad, A.A. 1991. A recombinant subunit vaccine that protects progeny chickens from infectious bursal disease. Avian Pathology, 20: 447-460.
21. Faragher, J.T., Allan, W.H. and Wyeth, C.J. 1974. Immunosuppressive effect of infectious bursal agent on vaccination against Newcastle disease. Veterinary Record, 95: 385-388.
22. Fodor, I., Horváth, E., Fodor, N., Nagy, E., Rencendorsh, A., Vakharia, V.N. and Dube, S.K. 1999. Induction of protective immunity in chickens immunised with plasmid DNA encoding infectious bursal disease virus antigens. Acta Veterinaria Hungarica, 47: 481-492.
23. Francois, A., Chevalier, C., Delmas, B., Eterradossi, N., Toquin, D., Rivallan, G. and Langlois, P. 2004. Avian adenovirus CELO recombinants expressing VP2 of infectious bursal disease virus induce protection against bursal disease in chickens. Vaccine, 22: 2351-2360.
24. Giambrone, J.J., Dormitorio, T. and Brown, T. 2001. Safety and efficacy of in ovo administration of infectious bursal disease viral vaccines. Avian Diseases, 45: 144-148.
25. st International Symposium on Infectious Bursal Disease and Chicken Infectious Anaemia 286 304. Rauischholzhausen, Germany.
26. Haddad, E.E., Whitfill, C.E., Avakian, A.P., Ricks, C.A., Andrews, P.D., Thoma, J.A. and Wakenell, P.S. 1997. Efficacy of a novel infectious bursal disease virus (IBDV) immune complex vaccine in broiler chickens. Avian Diseases, 41: 882-889.
27. Haygreen, E.A., Kaiser, P., Burgess, S.C. and Davison, T.F. 2006. In ovo DNA immunisation followed by a recombinant fowlpox boost is fully protective to challenge with virulent IBDV. Vaccine, 24: 4951-4961.
28. Heine, H.G. and Boyle, D.B. 1993. Infectious bursal disease virus structural protein VP2 expressed by a fowlpox virus recombinant confers protection against disease in chickens. Archives of Virology, 131: 277-292.
29. Hitchner, S.B. 1970. Infectivity of infectious bursal disease virus for embryonating eggs. Poultry Science, 49: 511-516.
30. Hsieh, M.K., Wu, C.C. and Lin, T.L. 2007. Priming with DNA vaccine and boosting with killed vaccine conferring protection of chickens against infectious bursal disease. Vaccine, 25: 5417-5427.
31. Hsieh, M.K., Wu, C.C. and Lin, T.L. 2010. DNA-mediated vaccination conferring protection against infectious bursal disease in broiler chickens in the presence of maternal antibody. Vaccine, 28: 3936-3943.
32. Huang, Z., Elankumaran, S., Yunus, A.S. and Samal, S.K. 2004. A recombinant Newcastle disease virus (NDV) expressing VP2 protein of infectious bursal disease virus (IBDV) protects against NDV and IBDV. Journal of Virology, 78: 10054-10063.
33. Hulse, D.J. and Romero, C.H. 2004. Partial protection against infectious bursal disease virus through DNA-mediated vaccination with the VP2 capsid protein and chicken IL-2 genes. Vaccine, 22: 1249-1259.
34. Icard, A.H., Sellers, H.S. and Mundt, E. 2008. Detection of infectious bursal disease virus isolates with unknown antigenic properties by reverse genetics. Avian Diseases, 52: 590-598.
35. Ignjatovic, J., Gould, G., Trinidad, L. and Sapats, S. 2006. Chicken recombinant antibodies against infectious bursal disease virus are able to form antibody-virus immune complex. Avian Pathology, 35: 293-301.
36. Islam, M.R., Zierenberg, K. and Müller, H. 2001a. The genome segment B encoding the RNA-dependent RNA polymerase protein VP1 of very virulent infectious bursal disease virus (IBDV) is phylogenetically distinct from that of all other IBDV strains. Archives of Virology, 146: 2481-2492.
37. Islam, M.R., Zierenberg, K., Raue, R. & Müller, H. 2001b, Molecular cloning and sequencing of a Bangladeshi strain of very virulent infectious bursal disease virus and its adaptation in tissue culture by site-directed mutagenesis. In Proceedings of the II. International Symposium on Infectious bursal Disease and Chicken Anaemia 30-39. Rauischholzhausen, Germany.
38. Iván, J., Velhner, M., Ursu, K., Germán, P., Mató, T., Drén, C.N. and Mészáros, J. 2005. Delayed vaccine virus replication in chickens vaccinated subcutaneously with an immune complex infectious bursal disease vaccine: quantification of vaccine virus by real-time polymerase chain reaction. Canadian Journal of Veterinary Research, 69: 135-142.
39. Jackwood, D.J., Cookson, K.C., Sommer-Wagner, S.E., Le Galludec, H. and de Wit, J.J. 2006. Molecular characteristics of infectious bursal disease viruses from asymptomatic broiler flocks in Europe. Avian Diseases, 50: 532-536.
40. Jackwood, D.J. and Sommer-Wagner, S.E. 2011. Amino acids contributing to antigenic drift in the infectious bursal disease Birnavirus (IBDV). Virology, 409: 33-37.
41. Jeon, W.J., Choi, K.S., Lee, D.W., Lee, E.K., Cha, S.H., Cho, S.H., Kwon, J.H., Yoon, Y.S., Kim, S.J., Kim, J.H. and Kwon, H.J. 2009. Molecular epizootiology of infectious bursal disease (IBD) in Korea. Virus Genes, 39: 342-351.
42. Jeurissen, S.H., Janse, E.M., Lehrbach, P.R., Haddad, E.E., Avakian, A. and Whitfill, C.E. 1998. The working mechanism of an immune complex vaccine that protects chickens against infectious bursal disease. Immunology, 95: 494-500.
43. Kumar, K., Singh, K.C. and Prasad, C.B. 2000. Immune responses to intermediate strain IBD vaccine at different levels of maternal antibody in broiler chickens. Tropical Animal Health and Production, 32: 357-360.
44. Le Nouen, C., Rivallan, G., Toquin, D., Darlu, P., Morin, Y., Beven, V., De Boisseson, C., Cazaban, C., Comte, S., Gardin, Y. and Eterradossi, N. 2006. Very virulent infectious bursal disease virus: reduced pathogenicity in a rare natural segment B-reassorted isolate. Journal of General Virology, 87: 209-216.
45. Le Gros, F.X., Dancer, A., Giacomini, C., Pizzoni, L., Bublot, M., Graziani, M. and Prandini, F. 2009. Field efficacy trial of a novel HVT-IBD vector vaccine for 1-day-old broilers. Vaccine, 22: 592-596.
46. Letzel, T., Coulibaly, F., Rey, F.A., Delmas, B., Jagt, E., van Loon, A.A. and Mundt, E. 2007. Molecular and structural bases for the antigenicity of VP2 of infectious bursal disease virus. Journal of Virology, 81: 12827-12835.
47. Li, J., Huang, Y., Liang, X., Lu, M., Li, L., Yu, L. and Deng, R. 2003. Plasmid DNA encoding antigens of infectious bursal disease viruses induce protective immune responses in chickens: factors influencing efficacy. Virus Research, 98: 63-74.
48. Li, J., Liang, X., Huang, Y., Meng, S., Xie, R., Deng, R. and Yu, L. 2004. Enhancement of the immunogenicity of DNA vaccine against infectious bursal disease virus by co-delivery with plasmid encoding chicken interleukin 2. Virology, 329: 89-100.
49. Li, L., Fang, W., Li, J., Huang, Y. & Yu, L. 2006, Oral DNA vaccination with the polyprotein gene of infectious bursal disease virus (IBDV) delivered by the attenuated Salmonella elicits protective immune responses in chickens. Vaccine, 24, 5919-5927.
50. Liu, Y., Wei, Y., Wu, X. and Yu, L. 2005. Preparation of ChIL-2 and VP2 fusion protein by baculovirus expression system. Cellular & Molecular Immunology, 2: 231-235.
51. Mahmood, M.S., Hussain, I., Siddique, M., Akhtar, M. and Ali, S. 2007. DNA vaccination with VP2 gene of very virulent infectious bursal disease virus (vvIBDV) delivered by transgenic E. coli DH5alpha given orally confers protective immune responses in chickens. Vaccine, 25: 7629-7635.
52. Martinez-Torrecuadrada, J.L., Sauri, N., Pagès-Manté, A., Castón, J.R., Espuña, E. and Casal, J.I. 2003. Structure-dependent efficacy of infectious bursal disease virus (IBDV) recombinant vaccines. Vaccine, 21: 3342-3350.
53. Mazariegos, L.A., Lukert, P.D. and Brown, J. 1990. Pathogenicity and immunosuppressive properties of infectious bursal disease "intermediate" strains. Avian Diseases, 34: 203-208.
54. Meeusen, E.N.T., Walker, J., Peters, A., Pastoret, P.-P. and Jungersen, G. 2007. Current status of veterinary vaccines. Clinical Microbiology Reviews, 20: 489-510.
55. Müller, H., Scholtissek, C. and Becht, H. 1979. The genome of infectious bursal disease virus consists of two segments of double-stranded RNA. Journal of Virology, 31: 584-589.
56. Müller, H., Schnitzler, D., Bernstein, F., Becht, H., Cornelissen, D. and Lütticken, D.H. 1992. Infectious bursal disease of poultry: antigenic structure of the virus and control. Veterinary Microbiology, 33: 175-183.
57. Müller, H., Islam, M.R. and Raue, R. 2003. Research on infectious bursal disease-the past, the present and the future. Veterinary Microbiology, 97: 153-165.
58. Müller, R., Käufer, I., Reinacher, M. and Weiss, E. 1979. Immunofluorescent studies of early virus propagation after oral infection with infectious bursal disease virus (IBDV). Journal of Veterinary Medicine, B, 26: 345-352.
59. Mundt, E. and Müller, H. 1995. Complete nucleotide sequences of 5'- and 3'-noncoding regions of both genome segments of different strains of infectious bursal disease virus. Virology, 209: 10-18.
60. Mundt, E. and Vakharia, V.N. 1996. Synthetic transcripts of double-stranded Birnavirus genome are infectious. Proceedings of the National Academy of Sciences U S A., 93: 11131-11136.
61. Mundt, E., de Haas, N. and van Loon, A.A. 2003. Development of a vaccine for immunization against classical as well as variant strains of infectious bursal disease virus using reverse genetics. Vaccine, 21: 4616-4624.
62. Noor, M. 2009, Development of infectious bursal disease virus vaccine candidates by reverse genetics. PhD Thesis, Bangladesh Agricultural University, Mymensingh Bangladesh.
63. Oberländer, Y. 2004, Generation and characterization of serotype 1-/serotype 2-recombinants of infectious bursal disease virus (IBDV). PhD Thesis, University of Leipzig, Leipzig Germany.
64. Öppling, V., Müller, H. and Becht, H. 1989. Heterogeneity of the antigenic site responsible for the induction of neutralizing antibodies in infectious bursal disease virus. Archives of Virology, 119: 211-223.
65. Oshop, G.L., Elankumaran, S., Vakharia, V.N. and Heckert, R.A. 2003. In ovo delivery of DNA to the avian embryo. Vaccine, 21: 1275-1281.
66. Park, J.H., Sung, H.W., Yoon, B.I. and Kwon, H.M. 2009. Protection of chicken against very virulent IBDV provided by in ovo priming with DNA vaccine and boosting with killed vaccine and the adjuvant effects of plasmid-encoded chicken interleukin-2 and interferon-gamma. Journal of Veterinary Science, 10: 131-139.
67. Perozo, F., Villegas, A.P., Fernandez, R., Cruz, J. and Pritchard, N. 2009. Efficacy of single dose recombinant herpesvirus of turkey infectious bursal disease virus (IBDV) vaccination against a variant IBDV strain. Avian Diseases, 53: 624-628.
68. Phenix, K.V., Wark, K., Luke, C.J., Skinner, M.A., Smyth, J.A., Mawhinney, K.A. and Todd, D. 2001. Recombinant Semliki Forest virus vector exhibits potential for avian virus vaccine development. Vaccine, 19: 3116-3123.
69. Pitcovski, J., Gutter, B., Gallili, G., Goldway, M., Perelman, B., Gross, G., Krispel, S., Barbakov, M. and Michael, A. 2003. Development and large-scale use of recombinant VP2 vaccine for the prevention of infectious bursal disease of chickens. Vaccine, 21: 4736-4743.
70. Raue, R., Islam, M.R., Islam, M.N., Islam, K.M., Badhy, S.C., Das, P.M. and Müller, H. 2004. Reversion of molecularly engineered, partially attenuated, very virulent infectious bursal disease virus during infection of commercial chickens. Avian Pathology, 33: 181-189.
71. Rautenschlein, S., Yeh, H.Y. and Sharma, J.M. 2002. The role of T cells in protection by an inactivated infectious bursal disease virus vaccine. Veterinary Immunology and Immunopathology, 89: 159-167.
72. Rautenschlein, S., Kraemer, Ch., Vanmarcke, J. and Montiel, E. 2005. Protective efficacy of intermediate and intermediate plus infectious bursal disease virus (IBDV) vaccines against very virulent IBDV in commercial broilers. Avian Diseases, 49: 231-237.
73. Rong, J., Jiang, T., Cheng, T., Shen, M., Du, Y., Li, S., Wang, S., Xu, B. and Fan, G. 2007. Large-scale manufacture and use of recombinant VP2 vaccine against infectious bursal disease in chickens. Vaccine, 25: 7900-7908.
74. Rosales, A.G., Villegas, P., Lukert, P.D., Fletcher, O.J. and Brown, J. 1989. Immunosuppressive potential and pathogenicity of a recent isolate of infectious bursal disease virus in commercial broiler chickens. Avian Diseases, 33: 724-728.
75. th Poultry Diseases Conference 105-109. Davis, California, USA.
76. Rosenberger, J.K., Cloud, S.S., Gelb, J., Odor, E. & Dohms, S.E. 1985, Sentinel birds survey of Delmarva broiler flocks. In Proceedings of the 20th National Meeting on Poultry Health and Condemnation 94-101. Ocean City, MD, USA.
77. Saif, Y. M. 1984, Infectious bursal disease virus type. In Proceedings of the 19th National Meeting on Poultry Health and Condemnations 105-107. Ocean City, MD, USA.
78. Saif, Y.M. 2004. Control of infectious bursal disease virus by vaccination. Developmental Biology, 119: 143-146.
79. Sapats, S.I., Trinidad, L., Gould, G., Heine, H.G., van den Berg, T.P., Eterradossi, N., Jackwood, D., Parede, L., Toquin, D. and Ignjatovic, J. 2006. Chicken recombinant antibodies specific for very virulent infectious bursal disease virus. Archives of Virology, 151: 1551-1566.
80. Schijns, V.E.J.C., Sharma, J. and Tarpy, I. 2008. "Practical aspects of poultry vaccination". In Avian Immunology, 1st edn, Edited by: Davison, F., Kaspers, B. and Schat, K.A. 373-393. London: Academic Press.
81. Schnitzler, A., Bernstein, F., Müller, H. and Becht, H. 1993. The genetic basis of the VP2 protein of the infectious bursal disease virus. Journal of General Virology, 74: 1563-1571.
82. Schröder, A., van Loon, A.A., Goovaerts, D. and Mundt, E. 2000. Chimeras in noncoding regions between serotypes I and II of segment A of infectious bursal disease virus are viable and show pathogenic phenotype in chickens. Journal of General Virology, 81: 533-540.
83. Schröder, A., van Loon, A.A., Goovaerts, D., Teifke, J.P. and Mundt, E. 2001. VP5 and the N terminus of VP2 are not responsible for the different pathotype of serotype I and II infectious bursal disease virus. Journal of General Virology, 82: 159-169.
84. Sun, J.H., Yan, Y.X., Jiang, J. and Lu, P. 2005. DNA immunization against very virulent infectious bursal disease virus with VP2-4-3 gene and chicken IL-6 gene. Journal of Veterinary Medicine, B, 52: 1-7.
85. Tsukamoto, K., Tanimura, N., Kakita, S., Ota, K., Mase, M., Imai, K. and Hihara, H. 1995. Efficacy of three live vaccines against highly virulent infectious bursal disease virus in chickens with or without maternal antibodies. Avian Diseases, 39: 218-229.
86. Tsukamoto, K., Kojima, C., Komori, Y., Tanimura, N., Mase, M. and Yamaguchi, S. 1999. Protection of chickens against very virulent infectious bursal disease virus (IBDV) and Marek's disease virus (MDV) with a recombinant MDV expressing IBDV VP2. Virology, 257: 352-362.
87. Tsukamoto, K., Saito, S., Saeki, S., Sato, T., Tanimura, N., Isobe, T., Mase, M., Imada, T., Yuasa, N. and Yamaguchi, S. 2002. Complete, long-lasting protection against lethal infectious bursal disease virus challenge by a single vaccination with an avian herpesvirus expressing VP2 antigens. Journal of Virology, 76: 5637-5645.
88. Vakharia, V.N., Snyder, D.B., He, J., Edwards, G.H., Savage, P.K. and Mengel-Whereat, S.A. 1993. Infectious bursal disease virus structural proteins expressed in a baculovirus recombinant confer protection in chickens. Journal of General Virology, 74: 1201-1206.
89. van den Berg, T. 2000. Acute infectious bursal disease in poultry: a review. Avian Pathology, 29: 175-194.
90. van Loon, A.A., de Haas, N., Zeyda, I. and Mundt, E. 2002. Alteration of amino acids in VP2 of very virulent infectious bursal disease virus results in tissue culture adaptation and attenuation in chickens. Journal of General Virology, 83: 121-129.
91. Wang, Y.S., Fan, H.J., Li, Y., Shi, Z.L., Pan, Y. and Lu, C.P. 2007. Development of a multi-mimotope peptide as a vaccine immunogen for infectious bursal disease virus. Vaccine, 25: 4447-4455.
92. Whitfill, C.E., Haddad, E.E., Ricks, C.A., Skeeles, J.K., Newberry, L.A., Beasley, J.N., Andrews, P.D., Thoma, J.A. and Wakenell, P.S. 1995. Determination of optimum formulation of a novel infectious bursal disease virus (IBDV) vaccine constructed by mixing bursal disease antibody with IBDV. Avian Diseases, 39: 687-699.
93. Wu, H., Singh, N.K., Locy, R.D., Scissum-Gunn, K. and Giambrone, J.J. 2004. Immunization of chickens with VP2 protein of infectious bursal disease virus expressed in Arabidopsis thaliana. Avian Diseases, 48: 663-668.
94. Wyeth, P.J. and Chettle, N. 1990. Use of infectious bursal disease vaccines in chicks with maternally derived antibodies. Veterinary Record, 126: 577-578.
95. Zierenberg, K., Nieper, H., van den Berg, Th., Ezeokoli, C.D., Voss, M. and Müller, H. 1999. The VP2 variable region of African and German isolates of infectious bursal disease virus: comparison with very virulent, "classical" virulent, and attenuated tissue culture-adapted strains. Archives of Virology, 144: 1-13.
96. Zierenberg, K., Raue, R., Nieper, H., Islam, M.R., Eterradossi, N., Toquin, D. and Müller, H. 2004. Reassortant serotype 1/serotype 2 infectious bursal disease viruses show that genome segment A determines bursa tropism whereas segment B is involved in the efficiency of viral replication. Virus Research, 105: 23-34.