Short-term antidepressant administration reduces negative self-referential processing in the medial prefrontal cortex in subjects at risk for depression

Molecular Psychiatry

Volumn 17, Issue 5, 2012, Pages 503-510

  Di Simplicio, M ^a,b   Norbury, R ^a,c   Harmer, C J ^a  

^a WARNEFORD HOSPITAL   (United Kingdom)

^b UNIVERSITY OF SIENA   (Italy)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

depression; emotion; neuroticism; prefrontal cortex; self referential; SSRI

Indexed keywords

CITALOPRAM; PLACEBO;

ADULT; ANTERIOR CINGULATE; ARTICLE; CLUSTER ANALYSIS; CONTROLLED STUDY; DEPRESSION; DISEASE COURSE; DOUBLE BLIND PROCEDURE; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HEMOPERFUSION; HIGH RISK POPULATION; HUMAN; HUMAN EXPERIMENT; INFORMATION PROCESSING; MALE; NORMAL HUMAN; ORBITAL CORTEX; PERSONALITY; PHENOTYPE; POPULATION RISK; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; VENTROMEDIAL PREFRONTAL CORTEX;

ADULT; CEREBROVASCULAR CIRCULATION; CITALOPRAM; DEPRESSION; EMOTIONS; FEMALE; FUNCTIONAL NEUROIMAGING; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; PERSONALITY; PREFRONTAL CORTEX; PSYCHIATRIC STATUS RATING SCALES; PSYCHOMOTOR PERFORMANCE;

EID: 84860122364     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/mp.2011.16     Document Type: Article

References (72)

1. Price JL, Drevets WC. Neurocircuitry of mood disorders. Neuropsychopharmacology 2010; 35: 192-216.
2. Phillips ML, Drevets WC, Rauch SL, Lane R. Neurobiology of emotion perception I: the neural basis of normal emotion perception. Biol Psychiatry 2003; 54: 504-514. (Pubitemid 37289437)
3. Phan KL,Wager T, Taylor SF, Liberzon I. Functional neuroanatomy of emotion: a meta-analysis of emotion activation studies in PET and fMRI. Neuroimage 2002; 16: 331-348. (Pubitemid 34852450)
4. Rolls ET, Grabenhorst F. The orbitofrontal cortex and beyond: from affect to decision-making. Prog Neurobiol 2008; 86: 216-244.
5. Ochsner KN, Gross JJ. The cognitive control of emotion. Trends Cogn Sci 2005; 9: 242-249. (Pubitemid 40615112)
6. Leppanen JM. Emotional information processing in mood disorders: a review of behavioral and neuroimaging findings. Curr Opin Psychiatry 2006; 19: 34-39. (Pubitemid 44406142)
7. Bradley BP, Mogg K, Millar N. Implicit memory bias in clinical and non-clinical depression. Behav Res Ther 1996; 34: 865-879.
8. Fu CH, Williams SC, Cleare AJ, Scott J, Mitterschiffthaler MT, Walsh ND et al. Neural responses to sad facial expressions in major depression following cognitive behavioral therapy. Biol Psychiatry 2008; 64: 505-512.
9. Yoshimura S, Okamoto Y, Onoda K, Matsunaga M, Ueda K, Suzuki S et al. Rostral anterior cingulate cortex activity mediates the relationship between the depressive symptoms and the medial prefrontal cortex activity. J Affect Disord 2010; 122: 76-85.
10. Beck AT. The evolution of the cognitive model of depression and its neurobiological correlates. Am J Psychiatry 2008; 165: 969-977.
11. Davidson RJ, Irwin W, Anderle MJ, Kalin NH. The neural substrates of affective processing in depressed patients treated with venlafaxine. Am J Psychiatry 2003; 160: 64-75. (Pubitemid 36042428)
12. Chen CH, Suckling J, Ooi C, Fu CH, Williams SC, Walsh ND et al. Functional coupling of the amygdala in depressed patients treated with antidepressant medication. Neuropsychopharmacology 2008; 33: 1909-1918. (Pubitemid 351832606)
13. Mayberg HS, Brannan SK, Tekell JL, Silva JA, Mahurin RK, McGinnis S et al. Regional metabolic effects of fluoxetine in major depression: serial changes and relationship to clinical response. Biol Psychiatry 2000; 48: 830-843.
14. Fu CH, Williams SC, Cleare AJ, Brammer MJ, Walsh ND, Kim J et al. Attenuation of the neural response to sad faces in major depression by antidepressant treatment: a prospective, eventrelated functional magnetic resonance imaging study. Arch Gen Psychiatry 2004; 61: 877-889. (Pubitemid 39181077)
15. Eugene F, Joormann J, Cooney RE, Atlas LY, Gotlib IH. Neural correlates of inhibitory deficits in depression. Psychiatry Res 2010; 181: 30-35.
16. Pardo JV, Sheikh SA, Schwindt GC, Lee JT, Kuskowski MA, Surerus C et al. Chronic vagus nerve stimulation for treatmentresistant depression decreases resting ventromedial prefrontal glucose metabolism. Neuroimage 2008; 42: 879-889.
17. Mayberg HS, Lozano AM, Voon V, McNeely HE, Seminowicz D, Hamani C et al. Deep brain stimulation for treatment-resistant depression. Neuron 2005; 45: 651-660. (Pubitemid 40320700)
18. Goldapple K, Segal Z, Garson C, Lau M, Bieling P, Kennedy S et al. Modulation of cortical-limbic pathways in major depression: treatment-specific effects of cognitive behavior therapy. Arch Gen Psychiatry 2004; 61: 34-41. (Pubitemid 38044639)
19. Dichter GS, Felder JN, Smoski MJ. The effects of Brief Behavioral Activation Therapy for Depression on cognitive control in affective contexts: an fMRI investigation. J Affect Disord 2010; 126: 236-244.
20. Harmer CJ. Serotonin and emotional processing: does it help explain antidepressant drug action? Neuropharmacology 2008; 55: 1023-1028.
21. Harmer CJ, Cowen PJ, Goodwin GM. Efficacy markers in depression. J Psychopharmacol 8 June 2010; e-pub ahead of print.
22. Harmer CJ, Mackay CE, Reid CB, Cowen PJ, Goodwin GM. Antidepressant drug treatment modifies the neural processing of nonconscious threat cues. Biol Psychiatry 2006; 59: 816-820.
23. Norbury R, Taylor MJ, Selvaraj S, Murphy SE, Harmer CJ, Cowen PJ. Short-term antidepressant treatment modulates amygdala response to happy faces. Psychopharmacology (Berl) 2009; 206: 197-204.
24. Murphy SE, Norbury R, O'Sullivan U, Cowen PJ, Harmer CJ. Effect of a single dose of citalopram on amygdala response to emotional faces. Br J Psychiatry 2009; 194: 535-540.
25. Norbury R, Mackay CE, Cowen PJ, Goodwin GM, Harmer CJ. The effects of reboxetine on emotional processing in healthy volunteers: an fMRI study. Mol Psychiatry 2008; 13: 1011-1020.
26. Kendler KS, Gatz M, Gardner CO, Pedersen NL. Personality and major depression: a Swedish longitudinal, population-based twin study. Arch Gen Psychiatry 2006; 63: 1113-1120. (Pubitemid 44498390)
27. Kendler KS, Myers J. The genetic and environmental relationship between major depression and the five-factor model of personality. Psychol Med 2010; 40: 801-806.
28. Chan SW, Goodwin GM, Harmer CJ. Highly neurotic never-depressed students have negative biases in information processing. Psychol Med 2007; 37: 1281-1291. (Pubitemid 47244858)
29. Chan SW, Harmer CJ, Goodwin GM, Norbury R. Risk for depression is associated with neural biases in emotional categorisation. Neuropsychologia 2008; 46: 2896-2903.
30. Canli T. Toward a neurogenetic theory of neuroticism. Ann N Y Acad Sci 2008; 1129: 153-174. (Pubitemid 351994149)
31. Haas BW, Constable RT, Canli T. Stop the sadness: Neuroticism is associated with sustained medial prefrontal cortex response to emotional facial expressions. Neuroimage 2008; 42: 385-392.
32. Eysenck SBG, Eysenck HJ. Manual of the EPQ (Eysenck Personality Questionnaire). University of London Press: London, 1975.
33. Spitzer RL, Williams G, Gibbon M. Structured Clinical Interview for the DSM-IV. New York State Psychiatric Institute: New York, 2002.
34. Spielberger CD, Gorsuch R, Lushene RD. Manual for the State-Trait Anxiety Inventory (STAI). Consulting Psychologists Press: Palo Alto, CA, 1983.
35. Beck AT,Ward CH, Mendelson M, Mock J, Erbaugh J. An inventory for measuring depression. Arch Gen Psychiatry 1961; 4: 561-571.
36. Weisman AN, Beck AT. Development and validation of the Dysfunctional Attitudes Scale: A preliminary investigation. American Education Research Association: Toronto, Canada, 1978.
37. Goodyer IM, Herbert J, Tamplin A, Secher SM, Pearson J. Short-term outcome of major depression: II. Life events, family dysfunction, and friendship difficulties as predictors of persistent disorder. J Am Acad Child Adolesc Psychiatry 1997; 36: 474-480. (Pubitemid 27149184)
38. von Zerssen D, Strian F, Schwarz D. Evaluation of depressive states, especially in longitudinal studies. Mod Probl Pharmacopsychiatry 1974; 7: 189-202.
39. Anderson N. Likeableness ratings of 555 personality-trait words. J Pers Soc Psychol 1968; 9: 272-279.
40. Francis W, Kucera A. Frequency Analysis of English Usage: Lexicon and Grammar. Houghton Mifflin: Boston, MA, 1982.
41. Harmer CJ, Shelley NC, Cowen PJ, Goodwin GM. Increased positive versus negative affective perception and memory in healthy volunteers following selective serotonin and norepinephrine reuptake inhibition. Am J Psychiatry 2004; 161: 1256-1263. (Pubitemid 38859176)
42. Miskowiak K, Papadatou-Pastou M, Cowen PJ, Goodwin GM, Norbury R, Harmer CJ. Single dose antidepressant administration modulates the neural processing of self-referent personality trait words. Neuroimage 2007; 37: 904-911. (Pubitemid 47248316)
43. MacIntosh BJ, Pattinson KTS, Gallichan D, Ahmad I, Miller KL, Feinberg DA et al. Measuring the effects of remifentanil on cerebral blood flow and arterial arrival time using 3D GRASE MRI with pulsed arterial spin labelling. J Cereb Blood Flow Metab 2008; 28: 1514-1522.
44. Smith SM, Jenkinson M, Woolrich MW, Beckmann CF, Behrens TE, Johansen-Berg H et al. Advances in functional and structural MR image analysis and implementation as FSL. Neuroimage 2004; 23(Suppl 1): S208-S219. (Pubitemid 39421720)
45. Jenkinson M, Bannister P, Brady M, Smith SM. Improved optimisation for the robust and accurate linear registration and motion correction of brain images. Neuroimage 2002; 17: 825-841. (Pubitemid 35317016)
46. Smith S. Fast and robust automated brain extraction. Hum Brain Mapp 2002; 17: 143-155. (Pubitemid 35253488)
47. Beckmann CF, Smith SM. Probabilistic independent component analysis for functional magnetic resonance imaging. IEEE Trans on Med Imaging 2004; 23: 137-152.
48. Woolrich MW, Ripley BD, Brady M, Smith SM. Temporal autocorrelation in univariate linear modeling of FMRI data. Neuroimage 2001; 14: 1370-1386. (Pubitemid 33124185)
49. Woolrich MW, Behrens TE, Beckmann CF, Jenkinson M, Smith SM. Multilevel linear modelling for FMRI group analysis using Bayesian inference. Neuroimage 2004; 21: 1732-1747. (Pubitemid 38446594)
50. Friston K, Worsley KJ, farckowiak RSJ, Mazziotta JC, Evans AC. Assessing the significance of focal activations using their spatial extent. Hum Brain Mapp 1994; 1: 210-220.
51. Talaraich J, Tournoux P. Co-planar stereotaxic atlas of the human brain: three-dimensional proportional system. Thieme Medical, New York, 1988.
52. Chappell MA, Okell TW, Jezzard P, Woolrich MW. Vascular territory image analysis using vessel encoded arterial spin labeling. Med Image Comput Comput Assist Interv 2009; 12 (Part 2): 514-521.
53. Nichols TE, Holmes AP. Nonparametric permutation tests for functional neuroimaging: a primer with examples. Hum Brain Mapp 2002; 15: 1-25. (Pubitemid 34020610)
54. Rudebeck PH, Bannerman DM, Rushworth MF. The contribution of distinct subregions of the ventromedial frontal cortex to emotion, social behavior, and decision making. Cogn Affect Behav Neurosci 2008; 8: 485-497.
55. Carmichael ST, Price JL. Sensory and premotor connections of the orbital and medial prefrontal cortex of macaque monkeys. J Comp Neurol 1995; 363: 642-664. (Pubitemid 26028726)
56. Bush G, Luu P, Posner MI. Cognitive and emotional influences in anterior cingulate cortex. Trends Cogn Sci 2000; 4: 215-222. (Pubitemid 30332147)
57. Haas BW, Omura K, Constable RT, Canli T. Emotional conflict and neuroticism: personality-dependent activation in the amygdala and subgenual anterior cingulate. Behav Neurosci 2007; 121: 249-256. (Pubitemid 47445076)
58. Mannie ZN, Norbury R, Murphy SE, Inkster B, Harmer CJ, Cowen PJ. Affective modulation of anterior cingulate cortex in young people at increased familial risk of depression. Br J Psychiatry 2008; 192: 356-361. (Pubitemid 351692380)
59. Gotlib IH, Hamilton JP, Cooney RE, Singh MK, Henry ML, Joormann J. Neural processing of reward and loss in girls at risk for major depression. Arch Gen Psychiatry 2010; 67: 380-387.
60. Longe O, Maratos FA, Gilbert P, Evans G, Volker F, Rockliff H et al. Having a word with yourself: neural correlates of self-criticism and self-reassurance. Neuroimage 2010; 49: 1849-1856.
61. Eugene F, Levesque J, Mensour B, Leroux JM, Beaudoin G, Bourgouin P et al. The impact of individual differences on the neural circuitry underlying sadness. Neuroimage 2003; 19 (2 Part 1): 354-364. (Pubitemid 39665686)
62. Ochsner KN, Ray RD, Cooper JC, Robertson ER, Chopra S, Gabrieli JD et al. For better or for worse: neural systems supporting the cognitive down-and up-regulation of negative emotion. Neuroimage 2004; 23: 483-499. (Pubitemid 39370600)
63. Cunningham WA, Raye CL, Johnson MK. Implicit and explicit evaluation: FMRI correlates of valence, emotional intensity, and control in the processing of attitudes. J Cogn Neurosci 2004; 16: 1717-1729. (Pubitemid 40052454)
64. Raichle ME, Snyder AZ. A default mode of brain function: a brief history of an evolving idea. Neuroimage 2007; 37: 1083-1090; discussion 97-9. (Pubitemid 47385262)
65. Sheline YI, Price JL, Yan Z, Mintun MA. Resting-state functional MRI in depression unmasks increased connectivity between networks via the dorsal nexus. Proc Natl Acad Sci USA 2010; 107: 11020-11025.
66. Sheline YI, Barch DM, Price JL, Rundle MM, Vaishnavi SN, Snyder AZ et al. The default mode network and self-referential processes in depression. Proc Natl Acad Sci USA 2009; 106: 1942-1947.
67. Lemogne C, Mayberg H, Bergouignan L, Volle E, Delaveau P, Lehericy S et al. Self-referential processing and the prefrontal cortex over the course of depression: a pilot study. J Affect Disord 2010; 124: 196-201.
68. Grimm S, Ernst J, Boesiger P, Schuepbach D, Hell D, Boeker H et al. Increased self-focus in major depressive disorder is related to neural abnormalities in subcortical-cortical midline structures. Hum Brain Mapp 2009; 30: 2617-2627.
69. Papageorgiou C, Wells A (eds). Depressive ruminatio: nature, theory and treatment. John Wiley and Sons: West Sussex, 2004.
70. Harmer CJ, Goodwin GM, Cowen PJ. Why do antidepressants take so long to work? A cognitive neuropsychological model of antidepressant drug action. Br J Psychiatry 2009; 195: 102-108.
71. Rawlings N, Norbury R, Cowen PJ, Harmer CJ. A single dose of mirtazapine modulates neural responses to emotional faces in healthy people. Psychopharmacology (Berl) 2010; 212: 625-634.
72. Harmer CJ, O'Sullivan U, Favaron E, Massey-Chase R, Ayres R, Reinecke A et al. Effect of acute antidepressant administration on negative affective bias in depressed patients. Am J Psychiatry 2009; 166: 1178-1184.