Strong immunogenicity and cross-reactivity of Mycobacterium tuberculosis ESX-5 type VII secretion-encoded PE-PPE proteins predicts vaccine potential

Cell Host and Microbe

Volumn 11, Issue 4, 2012, Pages 352-363

  Sayes, Fadel ^a,b   Sun, Lin ^a,b,e   Di Luca, Mariagrazia ^c   Simeone, Roxane ^a   Degaiffier, Nathalie ^a,b   Fiette, Laurence ^a,d   Esin, Semih ^c   Brosch, Roland ^a   Bottai, Daria ^c   Leclerc, Claude ^a,b   Majlessi, Laleh ^a,b  

^a INSTITUT PASTEUR   (France)

^b INSERM   (France)

^c UNIVERSITY OF PISA   (Italy)

^d LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

^e YANGZHOU UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BCG VACCINE; CULTURE FILTRATE PROTEIN 10; EARLY SECRETORY ANTIGENIC TARGET 6; EPITOPE; GAMMA INTERFERON; HERMES ANTIGEN; INTERLEUKIN 2; PROTEIN; PROTEIN PE; PROTEIN PPE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL VIRULENCE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL MATURATION; CELLULAR IMMUNITY; CONTROLLED STUDY; CROSS REACTION; FEMALE; GENETIC CODE; IMMUNOCOMPETENCE; IMMUNOGENICITY; INNATE IMMUNITY; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; TUBERCULOSIS;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, BACTERIAL; ANTIGENIC VARIATION; BACTERIAL PROTEINS; BACTERIAL SECRETION SYSTEMS; CROSS REACTIONS; FEMALE; HUMANS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, SCID; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM TUBERCULOSIS; PROTEIN TRANSPORT; TUBERCULOSIS; TUBERCULOSIS VACCINES;

EID: 84859965450     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2012.03.003     Document Type: Article

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